Cooperri Celulare Directe

Activarea LyB prin antigene T-dependente:

APC foliculare + LyB
APC medulare + LyTh0 -> LyTh2
LyB + LyTh2 -> Activarea LyB
Activarea LyT:
APC + LyTh0 -> LyTh1/2/17
APC + LyTc -> Activare LyTc
LyTc + Celule Infectate (Fas-FasL) -> Inducere Apoptoz
 Cooperri Celulare Indirecte
Activarea LyTh
M + LyTh0 -> LyTh1 (IL-12, IL-18, TNFa, TNFb)
M + LyTh0 -> LyTh2 (IL-4, aciune autocrin)
M + LyTh0 -> LyTh17 (IL-1, IL-6, IL-23)

LyTh1 + LyTc -> Activare LyTc (IL-2)

LyTh1 + M -> Activarea M (IFN-g)
LyTh2 + LyB -> Activare LyB (IL-4)
LyTh2 + LyB -> Switch al izotipului Ac LyB (IL-6)