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(Q.5) All are indications for post operative radiotherapy in a case of Carcinoma Endometrium EXCEPT?
(a) Myometrial invasion >1/2 thickness
(b) Positive lymph nodes
(c) Endocervical involvement
(d) Tumor positive for estrogen receptors
Your Response : d
Correct Answer : D
Exp: Tumor positive for estrogen receptors
Receptor positivity have no influence on postop radiotherapy.
As far as receptor status is concerned, the best correlation is that of a good prognosis with hig
progesterone receptors rather than a poor prognosis with high estrogen receptors
The best prognostic factor of cancer endometrium, amongst others, is the Histological gradin
disease
Other important predictors are:
Depth of myometrial invasion
Status of pelvic and para-aortic lymph nodes
Malignant cells in peritoneal washings
Lymph vascular invasion
Cervical invasion
(Q.13) A pregnant 35-yrs-old patient is at highest risk for the concurrent development of which malignancies?
(a) Cervix
(b) Ovary
(c) Breast
(d) Vagina
Your Response : c
Correct Answer : A
Exp: Cervix
Cervical cancer is a more common gynecologic malignancy in pregnancy than ovarian or br
due to the fact that it is a disease of younger women.
Management of cervical intraepithelial lesions is complicated in pregnancy because of increa
vascularity of the cervix and because of the concern that manipulation and trauma to the ce
compromise continuation of the pregnancy.
A traditional cone biopsy is only indicated in the presence of apparent microinvasive disease
colposcopically directed cervical biopsy Otherwise, more limited procedures such as shallow
are more appropriate.
If invasive cancer is diagnosed, the decision to treat immediately or wait until fetal viability d
on the gestational age at which the diagnosis is made and the severity o disorder.
Survival is decreased for malignancies discovered later in pregnancy Radiation therapy almo
results in spontaneous abortion, in part because the fetus is particularly radiosensitive.
Chemotherapy is associated with higher than expected rates of fetal malformations consiste
antimetabolite effects of agents used. Specific malformations depend on the agent used and
pregnancy at which the exposure occurs.
(Q.21) Premenopausal peripheral conversion of estrogen precursors in the obese patient results in formation of:
(a) Estriol
(b) Estradiol
(c) Estrone
(d) Androstenedione
Your Response : a
Correct Answer : C
Exp: Most common in non-pregnant women
In premenopausal adult women, most of the estrogen in the body is derived from ovarian se
estradiol, but a significant portion comes also from the extraglandular conversion of andros
estrone. To a lesser extent, testosterone conversion to estradiol also contributes to the estr
Muscle and adipose tissue are the major sites of aromatization. When there is an increase in
obese persons, estrogen levels will be higher, because adipose tissue exhibits a greater aro
androstenedione to estrone than does muscle.
(Q.22) A 59-yrs-old woman undergoes vaginal hysterectomy and anteroposterior repair for uterine prolapse. Which of the fo
complication of this procedure that often develops within 2 weeks of surgery?
(a) Dyspareunia
(b) Stress urinary incontinence
(c) Nonfistulous fecal incontinence
(d) Enterocele
Your Response : b
Correct Answer : B
Exp: Stress urinary incontinence
Many patients who have uterine prolapse or a large protuberant cystocele will be continent
urethra obstruction caused by the cystocele or prolapse.
In fact, at times these patients may need to reduce the prolapse in order to void. Following s
if the urethrovesical junction is not properly elevated, urinary incontinence may result.
This incontinence may present within the first few days following surgery.
Dyspareunia can be caused by shortening of the vagina or constriction at the introitus after h
complete.
If the vaginal vault is not properly suspended and the uterosacral ligaments plicated, vaginal
or enterocele may occur at a later date. Fecal incontinence is not a complication of vaginal h
with repair. It may occur, however, if a fistula is formed through unrecognized damage to th
mucosa.
(Q.23) Velamentous insertion of the cord is associated with an increased risk for:
(a) Premature rupture of the membranes
(b) Fetal exsanguinations before labor
(c) Torsion of the umbilical cord
(d) Fetal malformations
Your Response : b
Correct Answer : B
Exp: Fetal exsanguinations before labor
With velamentous insertion of the cord, the umbilical vessels separate in the membranes at
from the placental margin, which they reach surrounded only by amnion. It occurs in about 1
gestations but is quite common in multiple pregnancies. Feta malformations are more comm
mentous insertion the umbilical cord. When fetal vessels cross the internal us (vasa previa),
membranes may be accompanied by rupture of a fetal vessel, leading to fetal exsanguinatio
risk of premature rupture of membranes and of torsion of the umbilical cord has not been d
association with velamentous insertion of the cord.
(Q.25) A 65- year old woman complains of leakage of urine. The most common cause of this condition in such patient is
(a) Anatomic stress urinary incontinence
(b) Urethral diverticula
(c) Overflow incontinence
(d) Unstable bladder
Your Response : a
Correct Answer : D
Exp: Unstable bladder
As patients age, the incidence of vesicle instability or unstable bladder increases dramaticall
estrogen has been reported to decrease urgency, frequency, and nocturia in menopausal wo
on correction of stress urinary incontinence or vesicle instability is unclear. In the elderly pop
are also many transient causes of incontinence that the physician should consider. These inc
dementia, medications (especially a-adrenergic blockers), decreased patient mobility, endoc
abnormalities (hypercalcemia, hypothyroidism), stool impaction, and urinary tract infections
(Q.26) A 26-yrs-old patient has had three consecutive spontaneous abortions early in the second trimester. As part of an eva
this problem, the least useful test would be:
(a) Hysterosalpinogram
(b) Chromosomal analysis of the couple
(c) Endometrial biopsy in the luteal phase
(d) Postcoital test
Your Response : d
Correct Answer : D
Exp: Postcoital test
A major cause of spontaneous abortions in the first trimester is chromosomal abnormalitie
the causes of losses in the second trimester are more likely to be uterine or environmental in
Patients should be screened for thyroid function, diabetes mellitus, and collagen vascular dis
is also a correlation between patients with a positive lupus anticoagulant and recurrent misc
hysterosalpingogram should be performed to rule out uterine structural abnormalities, such
uterus, septate uterus, unicornuate uterus, submucous fibroids, or intrauterine adhesions. E
biopsy is performed to rule out an insufficiency of the uterus. If no abnormalities are found,
husband and wife should be karyotyped to see if a balanced translocation or 45,X mosaicism
A postcoital test is useful for couples who can not conceive, but does not address postconc
(Q.34) A 20 year old woman gives a history of sharp pain in the lower abdomen for 2-3 days every month approximately 2 w
the menses: The most probable etiology for her pain is
(a) Endometriosis
(b) Dysmenorrhea
(c) Pelvic tuberculosis
(d) Mittelschmerz
Your Response : a
Correct Answer : D
Exp: Mittelschmerz - Midcycle ovulatory pain occurs during oocyte release from an ovarian folicle
produces lateral pain that migrates from one side to the other from month to month.
Cyclic causes - include primary dysmenorrhea in which periods are painful but no pelvic path
Secondary dysmenorrhea due to endometriosis, adenomyosis, or perhaps chronic salpingitis
Gynecological causes of continuous pain include - later stages of endometriosis, adenomyos
prolapse, and chronic salpingitis or pelvic adhesions
Ovarian remment syndrome - occurs after oophorectomy when residual ovarian tissue is tra
retroperitoneal location.
(Q.35) Stain used for maturity assessment of amniotic fluid cells is:
(a) Congo red
(b) Lehman's stain
(c) Sudan red stain
(d) Nile blue sulphate
Your Response : d
Correct Answer : D
Exp: new question
With advancing maturity increasing numbers of cornified skin cells are shed into the amnioti
fetus. Because some come from sebaceous glands they contain lipid which when stained wit
sulphate become orange and when 10% of cells from an amniocentesis sample of fluid stain
pregnancy has reached at least 38 weeks and it has reached term or beyond when 50% reac
(Q.36) Complete or incomplete uterine inversion depends on whether fundus has passed through:-
(a) Cervix
(b) Vagina
(c) Introitus
(d) Hymen
Your Response : a
Correct Answer : A
Exp: Cervix
Types of inversion of uterus:
a. ONE: Complete. Visible outside thecervix.
b. TWO: Incomplete. Visible only at the cervix
Other way to describe inversion is first, second, third, or fourth degree. Acute inversion occu
hrs of delivery and is most common type. Subacute inversion presents from 24 hrs to 4 week
or chronic inversion which presents 4 weeks after delivery.
(Q.40) Technique used for aspiration of sperm directly from testes for in vitro fertilization is:
(a) TESA
(b) MESA
(c) GIFT
(d) IVF
Your Response : b
Correct Answer : A
Exp: TES(A).
Sperm aspiration technique involves the use of minor surgical procedures to collect sperms f
within the genital tract. In men in whom transport of sperms is not possible.
This may involve aspiration of sperms from the vas deferens, epididymis, or testicles.
In vitro fertilization is required to achieve pregnancy with the majority of these extraction pr
Procedure Source IVF
Vasal aspiration Vas deferens May be
Epididymal aspiration Epididymis Yes
Testicular aspiration Testicle Yes
Epididymal aspiration: is of two types:
- MESA: Microsurgical Epididymal Sperm
Aspiration
- PESA: Percutaneous Epididymal Sperm Aspiration
This is performed in situations in which vas is either not present or is scarred from prior surg
or infection.
Testicular sperm extraction (TESE, TESA)
The newest of the three aspiration techniques, testicular sperm retrieval is a breakthrough a
demonstrates that sperms donot have to mature and pass through epididymis in order to fe
Because of their immaturity, however, testicular sperms need to be injected directly into the
(intra cytoplasmic sperm injection) for fertilization to occur. Testicular sperm extraction is in
patients in whom there is blockade in the epididymis very close to where it attaches to the t
blockade with in ducts that conduct sperm out of the testis.
IVF( in vitro fertilization)
In this induction of ovulation is done followed by aspiration of mature oocytes under ultraso
50000 selected sperms are used for insemination and at 2 to 4 cell stage, three embryo tran
uterine cavity 1 cm below the fundus is performed.
GIFT(gamete intra fallopian transfer technique)
It involves aspiration of oocytes following ovulation induction. These are mixed with 50,000
sperms and transferred to ampullary portions of both the fallopian tubes 4 cm from the fimb
MESA and TESA are both techniques of sperm aspiration but since the question specifically a
aspiration directly from the testes, TESA is the most appropriate ans here.
(Q.41) All of the following are ultrasonographic fetal growth parameters except
(a) Head circumference
(b) Trans cerebellar diameter
(c) Femur length
(d) Biparietal diameter
Your Response : a
Correct Answer : B
Exp: Trans cerebellar diameter
Ultrasound imaging: Standard morphometric measurements are as under: Fetal crown-rump
trimester); Biparietal diameter; Head circumference;
Abdominal circumference; Femur length; and Total intrauterine volume.
(Q.42) The lesion listed below that would most likely pursue a benign course is :-
(a) Vaginal adenosis
(b) Adenomyosis
(c) Extramammary Pagets disease
(d) Endometrial hyperplasia
Your Response : a
Correct Answer : B
Exp: Adenomyosis
Adenomyosis is the presence of benign glands and stroma within the myometrium. It is a co
of diffuse uterine enlargement and menstrual irregularities; however, it is not a precancerou
Vaginal adenosis is a DES-related precursor lesion for clear cell adenocarcinoma- of the va
Extramammary Pagets disease is an intraepithelial adenocarcinoma. Endometrial hyperplas
precursor lesion of endometrial carcinoma. Anadenoacanthoma is an endometrial adenocar
benign component of mature squamous cells.
(Q.46) Nulliparity and late menopause are risk factors for which of the following group of diseases
(a) Cervical cancer and endometrial hyperplasia
(b) Ovarian cancer and endometrial polyp
(c) Vulvar cancer and endometrial cancer
(d) Endometrial cancer and breast cancer
Your Response : d
Correct Answer : D
Exp: Endometrial cancer and breast cancer
Nulliparity and late menopause are factors associated with increased exposure to estrogen,
are operative in endometrial hyperplasia, Unopposed estrogen stimulation is not operative i
polyps, cervical cancer, or vulvar cancer
(Q.48) Which of the following is correct for the calculation of Pearl index?
(No. of accidental pregnancies x 1200) / (No. of patients observed x months
(a) of use)
(b) (No. of accidental pregnancies x 1200) / (No. of patients observed x 2400)
(c) (No. of patients observed x months of use) / (No. of accidental pregnancies)
(d) (No. of patients observed) / (No. of accidental pregnancies x 2400)
Your Response
a
:
Correct Answer
A
:
Exp: (No. of accidental pregnancies x 1200) / (No. of patients observed x months
of use)
Pearl Index: Failure rate of any contraceptive is calculate din terms of
pregnancy rate per hundred women years of use. It is calculated by
following formula:
Number of accidental pregnancy x 1200
Pearl index = --------------------------------------------------
Number of patients observed x months of use
Here 1200 is the number of months in 100 years
(Q.49) There is a mid-cycle shift in the basal body tempt. after ovulation in women. This is caused by:
(a) FSH-peak
(b) LH-peak
(c) Estradiol
(d) Progesterone
Your Response : d
Correct Answer : D
Exp: Progesterone
Biphasic changes in basal body temperature are characteristic of the ovulatory cycle and are
alterations in progesterone levels. An increase in basal body temperature by 0.3 to 0.5C beg
ovulation, persists during the luteal phase, and returns to the normal baseline (36.2 to 36.4
onset of the subsequent menstruation.
(Q.50) A 24-year-old patient presents to OPD at 18 weeks of pregnancy with a previous history of a child with Down syndrom
appropriate is
(a) Triple test
(b) Chorionic villous biopsy
(c) Amniocentesis
(d) Cordocentesis
Your Response : b
Correct Answer : C
Exp: Amniocentesis
"Tripple test gives risk ratio and for further confirmation amniocenteses has to be done" Trip
(MSAFP,hCG, UE3) it is performed at 15-18 weeks while amniocenteses in performed at 16 w
pregnancy
The ultrasound nuchal translucency (NT) is now appreciated as a sensitive marker for Down
screening and other aneuploidies between 10 and 13 weeks.
Outside that range, the NT disappears. Although some centers have had superb results, othe
done well.
Blood free -hCG and PAPP-A in the first trimester, and double (AFP and hCG) or triple (AFP, h
at 15 to 20 weeks) evaluations are statistically comparable. The combination of NT and first-
biochemistry will likely be the optimal approach.
Biochemistry does not work well for multiple gestations. Ultrasound can also detect structur
but often high-quality ultrasound services require patients to travel long distances, whereas
shipped from essentially anywhere to a competent lab.
Quadruple test is use o Inhibin along with the standard three parameters
Cordocentesis (Percutaneous umbilical cord sampling) usually performed after 18 weeks ges
(Q.51) Most common serotype of HPV associated with invasive cervical carcinoma is?
(a) HPV 16
(b) HPV 18
(c) HPV 32
(d) HPV 36
Your Response : a
Correct Answer : A
Exp: HPV 16
HPV is associated with 80% of CIN and over 90% of invasive carcinoma
'HPV -16 is most common HPV associated with squamous cell carcinoma. HPV -18 is most co
associated with Aden carcinoma.' -CGDT 9th ed pg 904
As it is well known that histologically 95% of cervical ca are SCC and only 5% adenoca. Hence
most common serotype of HPV associated with cervical ca.
On the basis of strength of association to cacervix, HPV has been classified into:
Low risk type-6, 11, 42, 43
Causes CIN and condyloma acuminate
Intermediate risk-33, 35, 55, 52
Causes CINI and CIN that don't progress.
High risk- 16, 18,31,39,45,56,48,59
Causes high grade CIN that progresses to invasive ca.
(Q.53) A 32-week-pregnant woman with a history of two previous mid trimester abortions presents with regular contraction
The cervix is 2 cm dilated. All the following are done EXCEPT
(a) Tocolytics
(b) Dexamethasone
(c) Antibiotics
(d) Emergency encirclage
Your Response : d
Correct Answer : D
Exp: Emergency encirclage
Glucocorticoids (Dexamethasone) is advocated where the pregnancy is less than 34 weeks, t
fetal lung maturation so that the incidence of respiratory distress can be minimized
Antibiotics - Prophylactive antibiotics are given to minimize maternal and perinatal risk of in
ampicillin
Tocolytics - arrest the preterm labour and inhibit uterine contractions
Circlage operation - the operation should be done around 14 weeks of pregnancy or at leas
earlier than the lowest period of previous wastage, as early as the 10th weeks
Second trimester abortion - mostly due to cervical incompetence.
(Q.54) A 16-year-old girl presents with blind vaginal pouch with absence of uterus. Investigation to be done is
(a) Prolactin levels
(b) Karyotyping
(c) IVP
(d) FSH levels
Your Response : b
Correct Answer : B
Exp: Karyotyping - Indications
Patients with malformations suggestive of one of the recognized syndromes associated with a
chromosome aberration
Patients of any age who are grossly retarded physically or mentally especially if there are asso
anomalies
Any patients with ambiguous internal or external genitalia or suspected hermaphroditisms
Girl with primary amenorrhoea and boys with delayed pubertal development.
Males with learning or behavioral disorders who are taller than expected (Based on parental
Certain malignant & pre malignant disease
Parents of a patients with chromosomal translocations
Couples with history of multiple spontaneous abortion of unknown cause
Couples who are infertile after more common obstetric and urologic causes have been exclud
Prenatal diagnosis - advanced maternal age, previous child with chromosome aberration, intr
growth delay
(Q.57) A 17 year old unmarried girl presents with fever, nausea, vomiting, pallor and pain abdomen. She is having foul smell
stained discharge per vaginum. Your most likely diagnosis of this case IS
(a) Twisted ovarian cyst
(b) Typhoid with enteric perforation
(c) Pelvic abscess with septic peritonitis
(d) Ruptured ectopic pregnancy
Your Response : d
Correct Answer : C
Exp: Pelvic abscess with septic peritonitis
It is a case of septic abortion complicated by septic peritonitis and pelvic abscess. As the pat
unmarried she had some procedure as criminal abortion to terminate unwanted pregnancy.
twisted ovarian cyst, fever and vaginal discharge are absent. In ruptured ectopic pregnancy,
are there but fever is usually absent and vaginal discharge is not foul smelling, there is only s
per vaginam.
(Q.58) All the conditions mentioned below are associated with decreased fetal heart rate except
(a) Fetal movement
(b) Chronic hypoxia
(c) Cord compression
(d) Head compression
Your Response : a
Correct Answer : A
Exp: Fetal movement
Fetal movement is associated with increase in fetal heart rate .This forms the basis of non st
compression leads to vagal stimulation and thus bradycardia. Hypoxia and cord compression
hypoxia) will also lead to bradycardia.
(Q.59) With reference to fetal heart rate, a non-stress test is considered reactive when:
(a) Two fetal heart rate accelerations are noted in 20 mins
(b) One fetal heart rate acceleration is noted in 20 mins
(c) Two fetal heart rate accelerations are noted in 10 mins
(d) Three fetal heart rate accelerations are noted in 30 mins
Your Response : a
Correct Answer : A
Exp: Two fetal heart rate accelerations are noted in 20 mins
Ref: Dutta, 6th Edition (Revised 2009), Page no 609
Non-Stress Test: It is a non-invasive test designed to monitor fetal responses to movements
fetal heart rate with perceived fetal movements.
With movement, the fetus will increase its heart rate and should maintain this increase for s
seconds. If the movement stresses the fetus, the heart rate will drop quickly.
This test monitors the acceleration of heart rate and whether the fetus becomes stressed or
mother is asked to lay down for while the fetal heart rate is recorded with a disc-shaped Dop
ultrasound strapped around her abdomen, similar to the Doppler equipment used to listen t
heart rate.
The Doppler is attached to a monitor that graphs the fetal heart rate. She will report each tim
the baby move by pressing a button that makes an arrow on the graph. A normal fetus will r
rate at least 15 beats whenever it moves. If the baby shows two accelerations in heart rate l
15 seconds during the 20-minute test, it is read as normal or "reactive."
A reactive non-stress test (NST) is a reassuring sign of fetal well being. If the heart rate does
with movement or another 20 minutes of observation fails to meet the criteria, and then the
test is considered "non-reactive."
(Q.61) The following statements are true about intrauterine devices (IUD) except:
(a) Levonorgestrel releasing IUD has an effective life of 5 years
(b) IUD can be used for emergency contraception within 5 days
(c) The pregnancy rate of Lippes loop and Cu- T 200 are similar
(d) Multiload Cu-375 is a third generation IUD
Your Response : b
Correct Answer : D
Exp: USG
Ref: Dutta, 6th Edition (Revised 2009), Page no 549
Generation Device Example
First generation Non-medicated or inert Lippes Loop
IUDs
Second generation Copper IUDs Cu-7, Cu T 200; T Cu-220 C, T Cu-380 A
or
Ag; Nova T; Multiload devices (ML - Cu -
250 & ML- Cu -375)
Third generation Hormone releasing IUDs Progestasert
(Q.66) All the following are indications for termination of pregnancy in an APH patient EXCEPT
(a) 37 weeks
(b) IUD
(c) Transverse lie
(d) Significant bleeding
Your Response : d
Correct Answer : C
Exp: Transverse lie
The definite management - comprises prompt delivery, this is considered when ever
The patient has her first bout of bleeding after 37 completed weeks. Successful conservative
brings the patients upto 37 weeks. If the initial or a subsequent bout of bleeding is very seve
Patient is in labour
Evidence of maternal or fetal jeopardy
Intrauterine fetal death
(Q.71) Following suction evacuation for 10 weeks old missed abortion the lady presented with bleeding PV and pain after 4 d
probable cause would be?
(a) Uterine atony
(b) Cervical trauma
(c) Retained placental bits
(d) Uterine rupture
Your Response : c
Correct Answer : C
Exp: Retained placental bits
Incomplete abortion or retained products will present in this manner. Uterine atony and cer
would present preoperatively . Uterine perforation should also be identified at the time of p
sudden loss of resistance/ pressure. If missed and presenting later the patient would presen
abdominal symptoms as the risk of bowel injury is higher with suction and evacuation.
(Q.78) A patient with positive antiphospholipid antibodies would have all the following EXCEPT
(a) Recurrent foetal loss
(b) Venous thrombosis
(c) Thrombocytosis
(d) Neurological complications
Your Response : c
Correct Answer : C
Exp: Thrombocytosis
Ref: Dutta, 6th Edition (Revised 2009), Page no 169, 343, 636
Common obstetric complications associated with antiphosphoid syndrome
Recurrent fetal loss
IUGR
PIH venous thrombosis)
Placental abruption (2nd trimester
Recurrent thrombotic events (Arterial
Thrombocytopenia
Auto immune or connective tissue disease
Many of these patients have SLE like symptoms, but do not meet specific diagnostic
criteria for that disease
Livedo reticularis, skin ulcers, mental status changes and mitral regurgitation are also
noted
(Q.80) All are the criteria for medical management of ectopic pregnancy
except:
(a) Asymptomatic patient.
(b) Serum r3-hCG level < 2000 IU/L.
(c) Pregnancy diameter <5 cm.
(d) Unruptured tube.
Your
b
Response :
Correct
C
Answer :
Exp: Pregnancy diameter <5 cm
Criteria are:
Asymptomatic patient.
Serum -hCG level < 2000 IU/L.
Pregnancy diameter <2 cm.
Unruptured tube.
Non-active bleeding.
No fetal cardiac activity on USG.
< 100 ml blood in the pouch of Douglas.
(Q.89) A 20 year old primi at 32 weeks of gestation has polyhydraminos. She should be advised:-
(a) Bed Rest
(b) Artificial rupture of membranes
(c) Oral indomethacin
(d) Restriction of oral fluid
Your Response : d
Correct Answer : C
Exp: Oral indomethacin
Ref: Dutta, 6th Edition (Revised 2009), Page no 213
Medical treatment of hydramnios is indomethacin in dose of 2mgmlkg/day orally. It reduces
by foetal kidney. Such therapy may cause premature closure of ductus arteriosus. If the pat
respiratory distress due to hydramnios, then amniotic fluid is drained by amniocentesis. The
drainage is maintained at about 500 ml/hr, and a total of 1500 to 2000 ml is withdrawn such
drainage docs not increase the risk of placental abruption. Amniocentesis may cause entry o
organism into the amniotic cavity & development of chorioamnionitis which should be watc
(Q.90) A 28 year old female present with acute abdominal pain, vaginal bleeding, severe pallor, hypotension with amenorrh
weeks. The provisional diagnosis is:
(a) Uterine fibroid
(b) Ovarian cyst
(c) Ruptured ectopic pregnancy
(d) inevitable abortion
Your Response : c
Correct Answer : C
Exp:
Ref: Dutta, 6th Edition (Revised 2009), Page no 179 - 189
Diagnosis is a classical case of ruptured ectopic pregnant)'. Uterine fibroid usually present w
menorrhagia, amenorrhea is absent. Ovarian' cyst until twisted does not cause acute abdom
(Q.91) A 34-year-old female present with copious vaginal discharge with odour. Discharge is gray in color microscopic exami
clue cells. The treatment of choice is:-
(a) Azithromycin
(b) Fluconazole
(c) Metronidazole
(d) Clotrimazole
Your Response : c
Correct Answer : C
Exp: Ruptured ectopic pregnancy
Diagnosis is bacterial vaginosis. Clue cells are vaginal epithelium cells studded with coccobac
Metronidazole is drug of choice, organism is Gardnerella vaginalis. Discharge gives fishy sme
whiff test) on treating with KO(B).
(Q.92) Which of the following test is used to estimate the amount of feto-maternal hemorrhage?
(a) Coombs test
(b) Kleihauer betke test
(c) Lielys spectrophotometer
(d) Schrills test
Your Response : d
Correct Answer : B
Exp: Kleihauer betke test
Kleihauer-Betke test is used to estimate amount of fetal maternal hemorrhage. A maternal b
treated with an acid-dilution procedure allowing identification of fetal blood cells. Combs te
detection of antibodies (Rh) in Rh negative mother as a screening test. Liley spectrophotome
plotting amniotic fluid bilirubin in case of Rh sensitized mother after Amniocentesis. Shrill te
biopsy test in suspected Ca cervix. Gram iodine is used as a Stainer. Healthy' tissue stains bro
carcinomatous are a remains unstained.
(Q.93) In obstretics ultra sound commonly employed range of frequency is:-
(a) 3.5-5 MHZ (Million Cycle per second)
(b) 5 7.5 MHZ
(c) 1 2.5 MHZ
(d) 8 10 MHZ
Your Response : b
Correct Answer : A
Exp: 3.5-5 MHZ (Million Cycle per second)
Ref: Dutta, 6th Edition (Revised 2009), Page no 643
3.5- 5 MHZ is commonly used frequency of ultra sonic waves for obstetric ultra sound. A pie
crystal is used to generate the sound waves.
(Q.96) A 25 year old infertile lady is having menorrhagia. On examination an abdominal mass is palpable which is immobile.
examination- uterus and appendages are fixed. The most appropriate first line treatment in this case is
(a) Exploratory laparotomy
(b) Tubal microsurgery
(c) Anti tubercular drugs
(d) Hysterectomy
Your Response : c
Correct Answer : C
Exp: Anti tubercular drugs
Immobile abdominal mass with fixed uterus and appendages, when associated with menstru
an infertile woman, strongly favours the diagnosis of genital tuberculosis. The first line treat
tubercular drugs. Surgery in from of TAH with BSO required as last option. Tubal microsurge
contraindicated in genital tuberculosis. Exploratory laparotomy not done as first line measur
required when there is confusion in diagnosis.
(Q.99) A young woman presented with infertility. Hysterosalpingogram shows beaded fallopian tubes with clubbing of the a
Most likely diagnosis is
(a) Gonococcal infection
(b) Chlamydial infection
(c) Tuberculosis
(d) Herpes genitalis
Your Response : c
Correct Answer : C
Exp: Tuberculosis
Following findings strongly suggests tuberculosis salpingitis in Hysterosalpingo gram
(a) A rigid non peristaltic pipe-like tube, called lead pipe appearance
(b) Beading an variation in filling density
(c) Calcification of the tube
(d) Cornual block
(e) A jagged fluffiness of the tubal outline
(f) Vascular or lymphatic intravasation of the dye
(g) Tobacco-pouch seen at naked eye examination
**In a proven case of genital tuberculosis, hysterosalpingography is contraindicated, as it ma
infection
(Q.100) A 45-year-old female presents with polymenorrhoea for 6 months. On examination nothing abnormal was found. W
following is the next best line of management
(a) Give progesterone for 3 cycles
(b) Give OCP for 3 cycles
(c) Dilation and curettage
(d) Hysterectomy
Your Response : b
Correct Answer : C
Exp: Dilation and curettage
Poly menorrhea - or epimenorrhea, the menstrual cycle is reduced from the normal of 28 d
of two to three weeks and remain constant at that frequency.
Treatment - Dilation and curettage is a most effective short term method of controlling ute
longer term treatments will generally be directed towards the cause of the abnormal uterin
DUB due to chronic anovulation is treated with cyclic progestin therapy with OCP
Severe and intractable bleeding of a dysfunctional nature may rarely require hysterectomy
(Q.101) All the following are associated with breech presentation at full term EXCEPT?
(a) Cornual implantation of the placenta
(b) Congenital malformation
(c) Uterine anomaly
(d) Placenta accreta
Your Response : b
Correct Answer : D
Exp: Placenta Accreta.
Ref: Dutta, 6th Edition (Revised 2009), Page no 375
The following are the known factors responsible for breech presentation. In a significant n
cases, the cause remains obscure.
Prematurity It is the commonest cause of breech presentation.
Factors preventing spontaneous version: (a) Breech with extended legs (b) Twins (c) Oligoh
Congenital malformation of the uterus such as septate or bicornuate uterus (e) short cord,
absolute (e) intrauterine death of the fetus.
Favourable adaptation : (a) Hydrocephalus big head can be well accomdated in the wide f
Placenta praevia (c) Contracted pelvis (d) Cornufundal attachment of the placenta minim
of the fundus where the smaller head can be placed comfortably.
Undue mobility of the fetus: (a) Hydramnios (b) Multiparae with lax abdominal wall.
Fetal abnormality : Trisomies 13, 18, 21 and myotonic dystrophy due to alteration of fetal m
and mobility.
(Q.103) At what stage of delivery antibiotic prophylaxis should be given in caesarian section?
(a) At the onset of labour pain
(b) At rupture of membrane
(c) When umbilical cord has been clamped
(d) After placenta delivery
Your Response : b
Correct Answer : C
Exp: When umbilical cord has been clamped
Ref: Dutta, 6th Edition (Revised 2009), Page no 640
Infective agents are mostly polymicrobial, including gram positive, gram negative aerobes a
Generally antibiotics with broad spectrum activity are better. Use of ceftriaxone (1 gm), Ce
gm) or amoxicillin clavulanic acid (1.2 gm), by intravenous route is a reasonable choice. Sh
of 1-3 doses are to be given. This can reduce the cost compared to a full seven day course.
the mother is given after the umbilical cord has been clamped. This avoids antibiotic expos
baby. Bacteriology pattern and antibiotic sensitivity need to be monitored regularly by the
laboratory.
(Q.105) Provisional short antiretroviral regime given in peripartum period reduces risk of vertical transmission by
(a) 35%
(b) 50%
(c) 65%
(d) 75%
Your Response : b
Correct Answer : B
Exp: 50%
Ref: Dutta, 6th Edition (Revised 2009), Page no 300
Most transmission of HIV occurs during pregnancy and birth, breast feeding may account fo
infants becoming infected after delivery.
Studies have demonstrated that truncated regimens of zidovudine alone or with Lamivudin
mother during last few weeks of pregnancy or even during labour & delivery & to the infan
less reduced transmission to infant by 50% compared to placebo.
(Q.108) A 55 year old lady presenting to OPD with postmenopausal bleeding for 3 months has a 1 x1 an nodule on the anter
cervix, The most appropriate investigation to be done subsequently is
(a) Pap smear
(b) Punch biopsy
(c) Endocervical curettage.
(d) Colposcopy
Your Response : a
Correct Answer : B
Exp: Punch biopsy
Punch biopsy is required in all cases in which there is visible area of redness, an iodine nega
area of colposcopic abnormality.
A cone biopsy and curettage should be done when cytologic examination reveals moderate
dysplasia, carcinoma in situ, or perhaps invasive carcinoma.
(Q.110) A case of Gestational trophoblastic neoplasia belongs to high risk group if disease develop
after
(a) Hydatidiform mole
(b) Full term pregnancy
(c) Spontaneous
(d) Ectopic pregnancy abortion
Your Response
a
:
Correct
B
Answer :
Exp: Full term pregnancy
Ref: Dutta, 6th Edition (Revised 2009), Page no 193-202
Classification of gestational trophoblastic disease
H. mole - 1. Complete 2. Partial
Gestational trophoblastic tumors
Non metastatic
Metastatic - Low risk - no risk factors
High risk - any risk factors
Pyretherapy hCG level> 40,000 miu/mL
Duration> 4 months
Brain or liver metastasis
Prior chemotherapy failure
Antecedent term pregnancy
(Q.112) Which of the following hepatitis virus have significant perinatal transmission
(a) Hepatitis-E virus
(b) Hepatitis-C virus
(c) Hepatitis-B virus
(d) Hepatitis-A virus
Your Response : a
Correct Answer : C
Exp: Hepatitis-B virus
Ref: Dutta, 6th Edition (Revised 2009), Page no 291
Perinatal transmission
Hepatitis -B
The risk of chronic hepatitis B infection in neonate who does not receive immunoprophylax
vaccination is 40%
Vertical transmission is 10% in mother with negative HBe Ag
When the women are infected during the 2nd and 3rd trimester the neonatal infection is 6
respectively and virtually all are infected in the perinatal period
Hepatitis - C
A marked variation is noted in vertical transmission rates of HCV is 0- 36%
In hepatitis C VIR positive, HIV negative mothers, without history of IV drugs abuse or trans
exposure, the risk of HCV vertical transmission is 0-18%
In patients who are HIV negative with ongoing IV drug abuse or blood transfusion during pr
- 23% HIV positive mothers vertical transmission rates - 6 - 36%
(Q.120) A patient is receiving external beam radiation for treatment of metastatic endometrial cancer. The treatment field i
entire pelvis. Which of the following tissues within this radiation field is the most radiosensitive?
(a) Vagina
(b) Ovary
(c) Rectovaginal septum
(d) Bladder
Your Response : b
Correct Answer : B
Exp: Ovary
Different tissues tolerate different doses of radiation, but the ovaries are by far the most ra
They tolerate up to 2,500 rads, while the other tissues listed tolerate between 5,000 and 20
Acute evidence of excessive radiation exposure includes tissue necrosis and inflammation,
enteritis, cystitis, vulvitis, proctosigmoiditis, and possible bone marrow suppression.
Chronic effects of excessive radiation exposure are manifest months to years after therapy
vasculitis, fibrosis, and deficient cellular regrowth; these can result in proctitis, cystitis, fistu
and stenosis.
Successful radiation depends on (1) the greater sensitivity of the cancer cell compared with
and (2) the greater ability of normal tissue to repair itself after irradiation.
The maximal resistance to ionizing radiation depends on an intact circulation and adequate
oxygenation. Resistance also depends on total dose, number of portions, and time intervals
The relative resistance of normal tissue (cervix and vagina) in cervical cancer allows high su
approaching 15,000 to 20,000 rads to be delivered to the tumor with intracavitary devices,
of the inverse square law, significantly lower doses of radiation reach the bladder and rectu
The greater the fractionalization (number of portions the total dose is broken into), the bet
tissue tolerance of that radiation dose; hence 5,000 rads of pelvic radiation is usually given
fractions over 5 weeks, with approximately 200 rads being administered each day
(Q.123) The most important reason pelvic inflammatory disease (PID) must be recognized and treated promptly is to preven
(a) Pelvic pain syndrome
(b) Infertility
(c) Ectopic pregnancy
(d) Sepsis
Your Response : b
Correct Answer : D
Exp: Sepsis
Untreated PID can lead to formation of tubo-ovarian abscess (TOA). Mortali
rare, does occur, particularly in neglected cases in 'which a ruptured TOA ca
septic shock and death. In the United States, more than 150 deaths annually
attributed to PI(D).
(Q.124) Spiegelberg criteria is used for the diagnosis of
(a) Tubal pregnancy
(b) Ovarian pregnancy
(c) Cervical pregnancy
(d) Abdominal pregnancy
Your Response : b
Correct Answer : B
Exp: Ovarian pregnancy
The most common site of ectopic pregnancy is fallopian tube. Ectopic at other sites is seco
ruptured ectopic from fallopian tube unless proved otherwise. The criteria defining primary
these uncommon sites are as follows
Rubins----primary cervical, Speigelberg-----primary ovarian, Studdiford---------primary ab
pregnancy
(Q.126) A woman is found to have a unilateral invasive carcinoma of vulva that is 2 cm in diameter but not associated with e
lymph node spread. Initial management should consists of :
(a) Chemotherapy
(b) Radiation therapy
(c) Radical vulvectomy
(d) Radical vulvectomy and bilateral inguinal lymphadenectomy
Your Response : d
Correct Answer : D
Exp: Radical vulvectomy and bilateral inguinal lymphadenectomy
Women who have invasive vulvar carcinoma usually are treated surgically. If the lesion is u
associated with fixed or ulcerated inguinal lymph nodes, and does not involve the urethra,
or rectum, then treatment usually consists of radical vulvectomy and bilateral inguinal lymp
If inguinal lymph nodes show evidence of metastatic disease, bilateral pelvic lymphadenect
performed. Radiation therapy, though not a routine part of the management of women wh
vulvar carcinoma, is employed (as an alternative to pelvic exenteration with radical vulvect
treatment of women who have local, advanced carcinoma.
(Q.127) The ovarian tumor which is most likely to be associated with virilization
(a) Granulosa tumor
(b) Sertoli-Leydig cell tumor
(c) Immature teratoma
(d) Gonadoblastoma
Your Response : d
Correct Answer : B
Exp: Sertoli-Leydig cell tumor
Sertoli-Leydig cell tumors, which represent less than 1% of ovarian tumors, may produce s
virilization. Histologically, they resemble fetal testes; clinically, they must be distinguished f
functioning ovarian neoplasms as well as from tumors of the adrenal glands, since both adr
and Sertoli-Leydig tumors produce androgens. The androgen production can result in sebor
menstrual irregularity, hirsutism, breast atrophy, alopecia, deepening of the voice, and clito
Recurrences of Sertoli-Leydig cell tumors, which seem to have a low malignant potential, u
within 3 years of the original diagnosis. Granulosa and theca cell tumors are often associate
excessive estrogen production, which may cause pseudoprecocious puberty, post- menopa
or menorrhagia. These tumors are associated with endometrial carcinoma in 15% of patien
these tumors are quite friable, affected women frequently present with symptoms caused
rupture and intraperitoneal bleeding. Granulosa tumors are low-grade malignancies that te
more than 5 years after the initial diagnosis. Because their malignant potential is impossible
histologically, long- term follow-up is mandatory.
(Q.128) A 30-yrs-old diabetic female is concerned about pregnancy. She can be assured that which of the following risks is th
as for the general population.
(a) Preeclampsia and eclampsia
(b) Infection
(c) Fetal cystic fibrosis
(d) Postpartum hemorrhage after vaginal delivery
Your Response : d
Correct Answer : C
Exp: Cystic fibrosis
Maternal diabetes mellitus can affect a pregnant woman and her fetus in many ways. The d
of preeclampsia or eclampsia is about 4 times as likely as among nondiabetic women. Inf
more likely not only to occur but to be severe. The incidences of fetal macrosomia or death
dystocia are increased, and hydramnios is common. The likelihood of postpartum hemorrh
vaginal delivery and the frequency of cesarean section are both increased in diabetic wome
incidence of fetal genetic disorders such as cystic fibrosis is unaffected by diabetes.
(Q.132) A 21-yrs-old has difficulty voiding 6 hrs postpartum. The least likely cause is?
(a) Preeclampsia
(b) Infusion of oxytocin after delivery
(c) Vulvar hematoma
(d) Urethral trauma
Your Response : b
Correct Answer : A
Exp: Preeclampsia
An inability to void often leads to the diagnosis of a vulvar hematoma. Such hematomas are
enough to apply pressure on the urethra. Pain from urethral laceration is another reason w
difficulty voiding after delivery. Both general anesthesia, which temporarily disturbs neural
bladder, and oxytocin, which has an antidiuretic effect, can lead to an over distended bladd
inability to void. In this case an indwelling catheter should be inserted and left in for at leas
recovery of normal bladder tone and sensation. Preeclampsia often leads to edema, which
to diuresis postpartum.
(Q.135) A 27years old G2P2 comes to your clinic to take advice about contraceptive measure. She has delivered a male child
and presently lactating. She has no contraindication of any hormone use. She can be given-
(a) DMPA
(b) Minipill
(c) Levonorgestrol implants
(d) All of the above
Your Response : b
Correct Answer : B
Exp: Minipill
'Progesterone only contraceptives' including minipills, DMPA and LNG implants don't affe
of milk, therefore, they are the contraceptive of choice for breast feeding women.
ACDG recommendations for hormonal contraception fused by breast feeding women proge
contraceptives prescribed or dispended at discharge from the hospital to be starte2-3 week
(e.g. the first Sunday after the newborn is 2 weeks old).
Depot medroxyprogesterone acetate initiated at 6 weeks postpartum
Hormonal implants inserted at 6 weeks postpartum.
Combined estrogen-contraceptive, if prescribed, should not be started before weeks postp
when lactation is well established and the infant's nutritional status is well-monitored.
(Q.140) A 23-year old patient diagnosed with stage IA malignant ovarian germ cell tumor. Which of the following would be t
treatment-
(a) Unilateral oophorectomy
(b) Bilateral oophorectomy and hysterectomy
(c) Unilateral oophorectomy followed by chemotherapy
(d) Ovarian biopsy followed by chemotherapy
Your Response : b
Correct Answer : C
Exp: Unilateral oophorectomy followed by chemotherapy
Approximately 50% to 70% of germ cell malignancies are stage 1. Except for dysgenuinoma
incidence of bilaterality is 10-15%, these tumors are very rarely b/L. Therefore, U/L salpinn
oophorectomy, preserving the contra lateral and uterus, combined with surgical staging c
performed in most patients (particularly in young patient where fertility-sparing surgery is
few exceptions, all germ cell malignancies require postoperative chemotherapy.
(Q.142) 25 years old 2nd gravida with B negative blood group reaches in labour room in full dilatation. All the following norm
followed except:
(a) Cord blood to be saved in 2 vial plain & EDTA vial
(b) Early clamping of cord
(c) Avoidance of manual removal of placenta
(d) Liberal prophylactic use of ergometrine
Your Response : c
Correct Answer : D
Exp: Liberal prophylactic use of ergometrine
Use of ergot derivatives is contraindicated in Rh negative mother to avoid chances of feto
micro transfusions.
(Q.144) Which of the following methods of treating eclampsia has the LEAST effect on neonates
(a) Lytic cocktail regime
(b) MgSO4 regime
(c) Diazepam therapy
(d) Phenobarbitone therapy
Your Response : b
Correct Answer : B
Exp: MgSO4 regime
Magnesium sulfate to control convulsions
In more severe cases of preeclampsia as well as eclampsia, magnesium sulfate administere
is the effective anti convulsant agent without producing CNS depression in either the moth
infants
Because labour and delivery is a more likely time for convulsions to develop, women with p
Eclampsia usually are given magnesium sulfate during labour and for 24 hours postpartum
Magnesium sulfate is not given to treat hypertension
Monitoring with (I) Knee jerk (II) Urine out put (III) Respiratory rate
(Q.145) All of the followings are true regarding the pudendal nerve, except
(a) Sensory and motor
(b) Derived from S2,3,4
(c) Comes out through the lesser sciatic foramen
(d) Main nerve supply of pelvic organs
Your Response : b
Correct Answer : C
Exp: Comes out through the lesser sciatic foramen
The pudendal nerve is a mixed nerve in the pelvic region that innervates the skin over exte
of both sexes, as well as sphincters for the bladder and the rectum
The pudendal nerve originates in the sacral plexus; it derives its fibers from the ventral bra
second, third, and fourth sacral nerves (S2, S3, and S4)
It passes between the piriformis and coccygeus muscles and leaves the pelvis through the l
thegreater sciatic foramen
Remember: PIN structures leaves greater sciatic foramen and re-enters lesser sciatic fora
It crosses the spine of the ischium (lies posterior to it), and re-enters the pelvis through the
foramen.
It accompanies the internal pudendal vessels upward and forward along the lateral wall of
fossa, being contained in a sheath of the obturator fascia termed the pudendal canal
The pudendal nerve gives off the inferior rectal nerves. It soon divides into two terminal br
theperineal nerve, and the dorsal nerve of the penis (males) or the dorsal nerve of the clito
females).
The pudendal nerve innervates the penis and clitoris, bulbospongiosus and ischiocavernosu
areas around the scrotum, perineum, and anus.
At sexual climax, the spasms in the bulbospongiosus and ischiocavernous results in ejaculat
male and most of the feelings of orgasm in both sexes.
(Q.149) Using histological criteria to date endometrial development, which of the following is the earliest sign of ovulation?
(a) Gland coiling
(b) Stromal edema
(c) Neovascularization
(d) Glycogen accumulation
Your Response : d
Correct Answer : D
Exp: Glycogen accumulation
After ovulation the estrogen-primed endometrium responds to rising levels of progesteron
predictable manner. By day 17, glycogen accumulates in the basal portion of the glandula
creating subnuclear vacuoles and pseudo stratification. This is the first sign of ovulation th
in histological changes, and it is likely the result of direct progesterone action through prog
receptors expressed in the glandular cells.
(Q.150) Gender of the fetus is first evident by what gestational age (weeks) ?
(a) 6
(b) 8
(c) 12
(d) 16
Your Response : b
Correct Answer : C
Exp: 12
By the end of the 12th week of pregnancy, when the uterus usually is just palpable above t
pubis, the crown-rump length of the fetus is 6 to 7 cm. Centers of ossification have appeare
the fetal bones, and the fingers and toes have become differentiated. Skin and nails have d
scattered rudiments of hair appear. The external genitalia are beginning to show definitive
or female gender. The fetus begins to make spontaneous movements.
(Q.151) All are true statements about puerperal venous thrombosis except.
(a) It is most common (10 times) with caesarean section
(b) Heparin is contraindicated
(c) Dehydration correction during delivery is a preventive measure
(d) Advancing parity is a high risk factor
Your Response : c
Correct Answer : B
Exp: Heparin is contraindicated
The 3 important predisposing factors for puerperal venous thrombosis include - trauma, se
anemia.
Dehydration during delivery should be promptly corrected. Other risk factors are - advancin
parity, caesarean section (10 times more than vaginal birth), use of oestrogen in suppressio
obesity heart disease, antiphospholipid antibody syndrome.
Management include bed rest with foot end elevated, analgesics and anticoagulants - Hepa
N followed by 10000 U 5-6 hourly for 4-6 injections, to be continued for at least 7-10 days.
commonly used orally and used for maintenance of therapy.
(Q.152) In presence of secondary sexual characters cause screening for primary amenorrhea is done at
(a) 12years
(b) 14 years
(c) 16 years
(d) 18 years
Your Response : b
Correct Answer : C
Exp: 16 years
Primary amenorrhoea is defined as the absence of secondary sexual characters by 14 yrs
absence of menarche in the presence of secondary sexual characters till 16 yrs of age, In
of pubertal development the changes are as follows thelarche, increased growth spurt,
pubarche, menarche. As menarche is the last stage ,in case secondary sexual characters ha
to account for constitutional delay investigation is begun at 16 years.
(Q.155) Mothers with phenylketonuria (PKU) are at increased risk of having children with :
(a) Hydrocephaly
(b) Spina bifida
(c) Skeletal dysplasia
(d) Mental retardation
Your Response : d
Correct Answer : D
Exp: Mental retardation
Women with PKU who plan to conceive and are not already on a phenylalanine-restricted d
counseled to adhere to the diet before conception and throughout pregnancy. Phenylalanin
crosses the placenta, and high maternal serum levels can result in damage to the fetus or p
Hyperphenylalaninemia causes microcephaly with mental retardation and cardiac defects i
heterozygote fetus who otherwise would not be affected. Importantly, these defects can b
with maternal dietary treatment.
(Q.158) Meconium-stained amnionic fluid is closely associated with following neonatal outcome?
(a) Death
(b) Cerebral palsy
(c) Necrotizing enterocolitis
(d) None of the above
Your Response : c
Correct Answer : D
Exp: None of the above
Obstetrical teaching throughout the past century has included the concept that meconium
potential warning of fetal asphyxia.
In an investigation from Parkland Hospital, meconium was found to be a "low-risk" obstetri
because the perinatal mortality attributable to meconium was 1 death per 1000 live births.
(Q.161) Which is a true statement regarding the psychological symptoms of the climacteric?
(a) They are considerably less important than hormone levels
(b) They commonly include insomnia, irritability, frustration, and malaise
(c) They are related to a drop in gonadotropin levels
(d) They are not affected by environmental factors
Your Response : b
Correct Answer : B
Exp: They commonly include insomnia, irritability, frustration, and malaise.
Psychological symptoms during the climacteric occur at a time when much is changing in a
Steroid hormone levels are dropping, and the menses is stop ping. However, studies show t
factors to be unrelated to emotional symptoms in most women. Many factors, such as horm
environmental, and intrapsychic elements, combine to cause the symptoms of the climacte
insomnia; vasomotor instability (hot flushes, hot flashes); emotional lability; and genital tra
with vulvar, vaginal, and urinary symptoms.
(Q.163) Which of the following fetal factors are NOT associated with postterm pregnancy?
(a) Renal agenesis
(b) X-linked placental sulfatase deficiency
(c) Adrenal hypoplasia
(d) Anencephaly
Your Response : a
Correct Answer : A
Exp: Renal agenesis
Fetal-placental factors that have been reported as predisposing to postterm pregnancy incl
anencephaly, adrenal hypoplasia, and X-linked placental sulfatase deficiency.
These cause a lack of the usually high estrogen levels of normal pregnancy.
(Q.164) Which ultrasound measurements is the most reliable index of fetal size?
(a) Biparietal diameter
(b) Abdominal circumference
(c) Femur length
(d) Intrathoracic ratio
Your Response : c
Correct Answer : B
Exp: Abdominal circumference
The optimal ultrasonic method of estimating fetal size, and therefore growth restriction, w
Manning. Combining head, abdomen, and femur dimensions should in theory enhance the
predictions of fetal size. Unfortunately, any potential improvement is apparently lost by the
error inherent in measurement of each individual fetal dimension. As a result, abdominal ci
measurements have been accepted by most experts as the most reliable index of fetal size.
(Q.166) Which one of the following tumors involving the female genital tract has the WORST prognosis?
(a) Dysgerminoma in a 35-year-old
(b) Uterine choriocarcinoma in a 25-year-old with a recent history of molar pregnancy
(c) Granulosa cell tumor in a 40-year-old
(d) Serous cystadenocarcinoma of the ovary in a 45-year-old
Your Response : b
Correct Answer : D
Exp: Serous cystadenocarcinoma of the ovary in' a 45-year-old
Around 75% of serous cystadenocarcinoma of the ovary are in an advanced stage at
the time of diagnosis.
These tumors have a worse prognosis than any of the other tumors listed.
(Q.167) Treatment option in 34 weeks with uterine contraction
(a) Tocolytics for 3 more weeks
(b) Dexamethasone should be given
(c) Vacuum assisted delivery
(d) Caesarean section
Your Response : c
Correct Answer : A
Exp: Tocolytics for 3 more weeks
At 34 weeks there is no indication of caesarean section or vacuum assisted delivery. There
of dexamethasone at or more 34weeks. As no other details are mentioned the best option
3 weeks. If the question had specified 34 weeks with placenta previa with contractions then
option would be caesarean section.
(Q.168) The WORST prognosis in patients with endometrial carcinoma is found in patients with tumor involvement of the:
(a) Uterine cervix
(b) Upper vagina
(c) Bladder mucosa
(d) Parametrium
Your Response : c
Correct Answer : C
Exp: Bladder mucosa
Involvement of the bladder mucosa constitutes a stage IV tumor. The other examples give
stage II or III. The more advanced the stage of a tumor, the worse the prognosis.
(Q.170) Pregnant female with history of previous LSCS comes in labor with hematuria. The diagnosis is?
(a) Impending scar rupture
(b) Prolonged labor
(c) Urethral trauma
(d) Cystitis
Your Response
b
:
Correct Answer
A
:
Exp: Impending scar rupture
Rupture Uterus
Definition: Dissolution in the continuity of uterine wall anytime beyond 28
weeksQ of pregnancy.
Features of Uterine rupture (during labour)
a) Failure in progress of labour. b) Suprapubic pain.
c) Slight bleeding PV and Hematuria. d) Alteration in fetal heart rate.
e) Unexplained maternal tachycardia. f) Hypotension.
g) Tenderness over scar. h) Bladder tenesmus.
i) Ballooning of lower segment.
(Q.172) On follow up study, elevated CA 125 in a case of epithelial ovarian tumor should be further evaluated with?
(a) MRI
(b) CT Scan
(c) Yearly follow up
(d) Clinical examination and serial CA 125 monitoring
Your Response : d
Correct Answer : B
Exp: CT Scan
Evaluation of patients with suspected ovarian cancer should include measurement of serum
tumor marker CA-125.
CA-125 determinants are glycoproteins with molecular masses from 220 to 1000 kDa, and
radioimmunoassay is used to determine circulating CA-125 antigen levels. Between 80 an
patients with epithelial ovarian cancer have levels of CA-125 _ 35 U/mL.
Other malignant tumors can also elevate CA-125 levels, including cancers of the endometri
fallopian tubes, pancreas, breast, lung, and colon.
Certain nonmalignant conditions that can produce moderate elevations of CA-125 levels in
pregnancy, endometriosis, pelvic inflammatory disease, and uterine fibroids. About 1% of n
have serum CA-125 levels _35 U/mL.
(Q.175) The Investigation of choice in a 55-year-old postmenopausal women who has presented with postmenopausal bleed
is:
(a) Pap smear
(b) Fractional curettage
(c) Transvaginal ultrasound
(d) CA-125 estimation
Your Response : a
Correct Answer : B
Exp: Fractional curettage
Common causes of postmenopausal bleeding
Genital malignancy (Me)
Decubitus ulcer
DUB .
Urethral caruncle .
Senile endometritis
DIAGNOSIS
Speculum Examination
If a growth is found, punch biopsy is to be taken.
If no growth is visible and the cervix looks apparently healthy
. Cervical smear
Aspiration cytology
Fractional curettage, if the cervical cytology becomes negative.
Hysteroscopic evaluation and directed biopsy.
Laparoscopy in suspected cases of ovarian or adnexal mass.
Detection of a benign lesion should not prevent further detailed investigations to rule out
malignancy.
(Q.177) If the twins are formed by fertilization of two separate ova, which of the following condition could not occur?
(a) Fetus papyraceous
(b) Fetus acardiacus
(c) Vanishing twin
(d) Pre-eclampsia
Your Response : a
Correct Answer : B
Exp: Fetus acardiacus
Fetus acardiacus occurs only in monozygotic twins. Parts of the fetus remains amorphous a
parasitic without a heart.
(Q.179) All are true about non-immune fetal hydrops (NIFH) Except
(a) May be related to toxoplasma infection
(b) Accumulation of extracellular fluid in tissues and serous cavities
(c) In presence of structural abnormality prognosis is usually good
(d) Doppler's flow study is useful in prenatal diagnosis
Your Response : b
Correct Answer : C
Exp: In presence of structural abnormality prognosis is usually good
NIHF is defined as accumulation of extra-cellular fluid in tissues and serous cavities in cond
than Rh incompatibility. The various etiologies are chromosomal, congenital, structural ano
hematological infections, placental factors, maternal diseases and idiopathic. Parvovirus, to
syphilis and rubella may cause NIHF. Prenatal diagnosis is possible with high resolution ultr
Doppler's flow study and cordocentesis. Perinatal mortality is high in 50-100%. Prognosis is
worse with presence of structural abnormalities.
(Q.183) Intrapartum automated fetal ECG has the advantage over conventional cardiotocography of :
(a) Improving neonatal outcome
(b) Decreasing caesarean section rate
(c) Decreasing need for fetal blood sampling during labour.
(d) All of the above
Your Response : b
Correct Answer : C
Exp: Decreasing the need for fetal blood sampling during labour.
Intrapartum automated fetal electrocardiography decreases the need for fetal blood sampl
labour in comparison with conventional cardiotocography, however it has no impact on ne
come and it does not decreases caesarean section rate.
(Q.188) Fetal biophysical profile used for the assessment of fetal well being does not
includes:
(a) Fetal breathing movements
(b) Fetal tone
(c) Amount fluid volume
(d) Fetal blood PH
Your
d
Response :
Correct
D
Answer :
Exp: Fetal blood PH
Fetal biophysical profile considers several parameters, which
includes:
. Non Stress test . Fetal breathing movements
. Gross body movements . Fetal muscle tone . Amniotic
fluid volume
(Q.5) Most common serotype of HPV associated with invasive cervical carcinoma is?
(a) HPV 16
(b) HPV 18
(c) HPV 32
(d) HPV 36
Your Response :
Correct Answer : a
Exp: HPV is associated with 80% of CIN and over 90% of invasive carcinoma
'HPV -16 is most common HPV associated with squamous cell carcinoma. HPV
common HPV associated with Aden carcinoma.' -CGDT 9th ed pg 904
As it is well known that histologically 95% of cervical ca are SCC and only 5% a
Hence HPV is the most common serotype of HPV associated with cervical ca.
On the basis of strength of association to cacervix, HPV has been classified int
Low risk type-6, 11, 42, 43
Causes CIN and condyloma acuminate
Intermediate risk-33, 35, 55, 52
Causes CINI and CIN that don't progress.
High risk- 16, 18,31,39,45,56,48,59
Causes high grade CIN that progresses to invasive ca.
(Q.6) Shape of nulliparous cervix is:
(a) Transverse
(b) Longitudinal
(c) Circular
(d) T shaped
Your Response :
Correct Answer : c
Exp: Shape of nulliparous cervix is circular the cervix is spindle shaped and measure
is bounded above by internal os and below by external os. In nulliparous wom
external os is circular whereas parous cervix is characterized by a transverse s
(Q.21) All the following drugs are used for postcoital contraception except
(a) Danazol
(c) Levonorgestrel
(d) Mifepristone
Your Response :
Correct Answer : a
Exp:
Postcoital contraceptive agents interfere with postovulatory events leading t
and are known as interceptive. They are chiefly used following rape, unprote
intercourse or accidental rupture of a condom during coitus which takes plac
ovulation. These agents are:
1. 2 tablets of relatively high doses of combined pill containing
100g ethinyl estradioland 1mg norethisterone are taken within 72 hours of
followed by 2 tablets taken 12 hours later.
2. Ethinyl estradiol 5 mg daily for 5 days starting within 72 hours of exposu
Stilboestrol 50 mg daily for 5 days.
3. IV equine conjugated estrogen twice daily
4. Levonorgestrel 600 g and d norgestrel .5-4 mg for 5 days.
5. RU 486 (Mifepristone)
(Q.22) Treatment of choice for carcinoma cervix stage IB is:
(a) Radiotherapy
(b) External hysterectomy
(c) Abdominal hysterectomy
(d) Pan-hysterectomy
Your Response :
Correct Answer : a
Exp: Carcinoma cervix in situ (stage 0) can generally be successfully managed by c
or by abdominal hysterectomy. For stage I disease, results appear equivalent
radical hysterectomy or radiation therapy. Patients with stages II to IV diseas
primarily managed with radical radiation therapy.
(Q.33) All of the following ovarian tumours arise from surface epithelium EXCEPT:
(a) Mucinous cystadenoma
(b) Endometrial carcinoma
(c) Brenner tumour
(d) Benign cystic teratoma
Your Response
:
Correct
d
Answer :
Exp: NOTE: Teratoma is a germ cell tumour. Other ovarian germ
cell tumours are:
1. Dysgerminoma
2. Endo dermal sinus (yolk sac) tumour
3. Chorio carcinoma
4. Embryonal cell carcinoma
Serous cystadenoma arises from surface epithelium,
Sex - cord stromal tumours of ovary
1. Granulosa cell tumour
2. Theca cell tumour
3. Arrhenoblastoma
4. Gynandroblastoma
5. Hilus cell tumour
Most common connective tissue tumour of ovary is ovarian
fibroma.
(Q.34) Which of the following type of anesthesia is frequently associated with fetalbradycardia:
(a) Paracervical block
(b) Pudendal block
(c) Spinal block
(d) Epidural block
Your Response :
Correct Answer : a
Exp: Pudendal block is perhaps the most common form of anesthesia used for vag
delivery. It provides adequate pain relief for episiotomy, spontaneous deliver
delivery, or vacuum extraction. The success of a pudendal block depends on
understanding of the anatomy of the pudendal nerve and its surroundings.
Complications (vaginal hematomas, retropsoas, or pelvic abscesses) are quite
Paracervical block was a popular form of anesthesia for the first stage of labo
was implicated in several fetal deaths. It has been shown that paracervical bl
associated with fetal bradycardia in 25 to 35% of cases, probably the respons
uptake of the drug from the highly vascular paracervical space with a resultan
of uteroplacental blood flow. Death in some cases was related to direct injec
local anesthetic into the fetus.
(Q.43) Ideal time for post partum ligation of fallopian tube in a patient of heart disease is:
(a) Immediately after delivery
(b) One day after delivery
(c) One week after delivery
(d) Six weeks after delivery
Your Response :
Correct Answer : c
Exp: The operation should be done under local anaesthesia by minilap technique
IMPORTANT: Oral contraceptive pill is contraindicated in heart disease as it m
precipitate thromboembolic phenomenon. lUCDs are contraindicated due to
infection. Barrier contraceptive is the best if the family is not complete.
(Q.44) A pelvis characterized by an anteroposterior diameter of the inlet greater than the transverse diam
classified as
(a) Gynecoid
(b) Android
(c) Anthropoid
(d) Platypelloid
Your Response :
Correct Answer : c
Exp: By tradition, pelvis are classified as belonging to one of four major groups. Th
pelvis is the classic female pelvis with a posterior sagittal diameter of the inle
slightly shorter than the anterior sagittal diameter. In the android pelvis, the
sagittal diameter at the inlet is much shorter than the anterior sagittal diame
the use of the posterior space by the fetal head. In the anthropoid pelvis, the
anteroposterior (AP) diameter of the inlet is greater than the transverse diam
resulting in an oval with large sacrosciatic notches and convergent side walls.
spines are likely to be prominent. The platypelloid pelvis is flattened with a sh
wide transverse diameter. Wide sacrosciatic notches are common. The pelve
women do not fall into a pure type and are blends of one or more of the abo
(Q.47) During the delivery, it is necessary to do an episiotomy. The tear extends through sphincter of the
the rectal mucosa is intact. How would you classify this type of episiotomy?
(a) First- degree
(b) Second-degree
(c) Third-degree
(d) Fourth-degree
Your Response :
Correct Answer : c
Exp: A first-degree tear involves the vaginal mucosa or perineal skin, but not the u
tissue. In a second-degree episiotomy, the underlying subcutaneous tissue is
involved, but not the rectal sphincter or rectal mucosa. In a third-degree tear
sphincter is affected. A fourth-degree episiotomy involves a tear that extend
rectal mucosa.
(Q.48) Episiotomy is best done:
(a) Medially
(b) Laterally
(c) Mediolaterally
(d) J shaped
Your
Response :
Correct
c
Answer :
Exp: (Ref. Textbook of Obstetrics D.C. Dutta 6th Ed.
606)
Types of episiotomy:
Mediolateral (best and routinely done)
Median
Lateral
J shaped
Only mediolateral or median episiotomy is done
commonly.
(Q.51) Which of the following abnormalities of labor is associated with a significantly increased incidence
neonatal morbidity?
(a) Prolonged latent phase
(b) Protracted descent
(c) Secondary arrest of dilation
(d) Protracted active-phase dilation
Your Response :
Correct Answer : c
Exp: Three significant advances in the treatment of uterine dysfunction have redu
of perinatal morbidity and mortality: (1) the avoidance of undue prolongation
(2) the use of intravenous oxytocin in the treatment of some patterns of uter
dysfunction; and (3) the liberal use of cesarean section (rather than midforce
to effect delivery when oxytocin fails. Prolonged latent phase is not associate
increased risk of perinatal morbidity (PNM) or low Apgar scores and should b
therapeutic rest. Pro traction disorders have a higher rate of PNM and low Ap
but not if spontaneous labor follows the abnormality Arrest disorders are ass
significantly higher rates of PNM following either spontaneous or instrument
delivery
(Q.52) Emergency contraception is contraception provided to:
(a) Contraceptive failure
(b) Couple not wanting to use other contraceptives
(c) Contraception provided to couple living in camps provided by governmen
(d) Unprotected intercourse
Your Response :
Correct Answer : d
Exp: Emergency postcoital contraception is defined as the use of a drug or device
pregnancy after unprotected sexual intercourse. Candidates for emergency
contraception include reproductive-aged women who have had unprotected
intercourse within 72 hours of presentation independent of the menstrual cy
(Q.53) Secondary amenorrhoea after abortion due to intrauterine adhesions is seen in:
(a) Uterine inertia
(b) Imperforate hymen
(c) Bicomuate uterus
(d) Asherman's syndrome
Your Response :
Correct Answer : d
Exp: Causes of Asherman 's syndrome are
i. Vigorous curettage ii. Abortion and MTP
iii. Puerperal infection iv. Endometrial tuberculosis
Diagnostic investigations for Asherman's syndrome - hysterosalpingography
and hysteroscopy.
Treatment of choice - Breaking of intrauterine adhesions by uterine sound
under anaesthesia.
(Q.54) False regarding dermoid cyst of ovary is:
(a) Bilateral in 35% of cases
(b) > 10 cm
(c) Lined by epithelial cells
(d) Has sebaceous material
Your Response :
Correct Answer : a
Exp: Of all cystic tumors of ovary 5-1 0% are dermoids. Dermoid cysts are usually u
swelling with smooth surfaces, seldom attaining more than 15 cm in diamete
contain sebaceous material and hair and the wall is lined in part by squamou
which contains hair follicles and sebaceous glands. Teeth, bone, cartilage, thy
and bronchial mucous membrane are often found in the wall. Dermoid cysts
arise in association with pseudomucinous cystadenomas to form a combined
They are not infrequently bilateral, 12%. Dermoid cysts are innocent ovarian
epidermoid carcinoma occurs in 1.7% of all dermoids and sarcomatous chang
also been described.
Your Response :
Correct Answer : d
Exp:
(Q.67) A patient treated for infertility presents with 8 weeks' amenorrhoea, retention of urine and abdom
Diagnosis is
(a) Impacted cervical fibroid
(b) Retroverted gravid fibroid
(c) Pelvic hematocele
(d) Uterine hematoma
Your Response :
Correct Answer : c
Exp: Pelvic hematocele - may follow an instrumental delivery, a paracervical or pu
block anaesthesia, vigorous ironing of the lower vagina and perineum during
even rarely after a normal delivery.
Retroverted gravid uterus - causes urinary retention at 12 weeks of gestation
The patients treated with infertility most likely the incidence of ectopic pregn
much higher presents with amenorrhoea (75%), Abdominal pain (95%), vagin
retention of urine
Retention of urine - In a subacute variety of ectopic pregnancy, the blood col
pouch of Douglas to form a pelvic haemotocele, this haematocele forms an ir
mass of differing consistency due to a mixture of clot and blood, and bulges f
displacing the cervix against the bladder and leading to retention of urine
Cervical fibroid in the cervix or lower uterine segment may obstruct labour an
confused with the fetal head.
(Q.68) Puerperium is the period:
(a) 6 wks following delivery
(b) 3 wks following delivery
(c) 1 wk following delivery
(d) None of the above
Your Response :
Correct Answer : a
Exp: (Ref. Textbook of Obstetrics D.C. Dutta 6th Ed. 153)
Purperium begins as soon as the placenta is expelled and lasts for approxima
when the uterus becomes regressed almost to the nonpregnant size.
(Q.69) A 30-year-old female has a history of two previous anencephalic pregnancies. The chances of the n
pregnancy being anencephalic are
(a) 10%
(b) 40%
(c) 20%
(d) 25%
Your Response :
Correct Answer : a
Exp: Anencephali - most severe defect in which the forebrain meninges, vault of t
scalp all fail to form
Recurrence rate
7.8% with high spina bifida
0.7% with low spina bifida
2.2% with anencephaly and no increased risk of r craniorachischisis, encepha
multiple defects
Neural tube defects are classical examples of multi factorial inheritance
The empirical recurrence risk of first degree relatives is usually quoted as 2-3
factorial inheritance
(Q.70) Best reversal after tubectomy is in which of the following types?
(a) Isthemo-isthemic
(b) Isthemo-ampullary
(c) Ampullo-ampullary
(d) Cornual implantation
Your Response :
Correct Answer : a
Exp: Tubal ligation reversal utilizes the techniques of microsurgery to open and re
fallopian tube segments that are remaining after a tubal sterilization procedu
Microsurgery minimizes tissue damage and bleeding during surgery.
Essential elements of microsurgical technique include gentle tissue handling,
the operating field, keeping body tissues in their normal state with warmed i
fluids, and using the smallest sutures with the thinnest needles capable of ho
tubal ends together to promote proper healing of the rejoined tubal segmen
An Isthemo-isthemic anastomosis has the best outcome with live birth rates
provided that the reconstructed tube is longer than 4cm and the ampullary p
more than 1cm.
(Q.75) Technique used for aspiration of sperm directly from testes for in vitro fertilization is:
(a) TESA
(b) MESA
(c) GIFT
(d) IVF
Your Response :
Correct Answer : b
Exp: Sperm aspiration technique involves the use of minor surgical procedures to
sperms from organs within the genital tract. In men in whom transport of spe
possible.
This may involve aspiration of sperms from the vas deferens, epididymis, or t
In vitro fertilization is required to achieve pregnancy with the majority of the
extraction procedures.
Procedure Source IVF
Vasal aspiration Vas deferens May be
Epididymal aspiration Epididymis Yes
Testicular aspiration Testicle Yes
Epididymal aspiration: is of two types:
- MESA: Microsurgical Epididymal Sperm
Aspiration
- PESA: Percutaneous Epididymal Sperm Aspiration
This is performed in situations in which vas is either not present or is scarred
surgery, trauma, or infection.
Testicular sperm extraction (TESE, TESA)
The newest of the three aspiration techniques, testicular sperm retrieval is a
breakthrough as it demonstrates that sperms donot have to mature and pass
epididymis in order to fertilize an egg. Because of their immaturity, however,
sperms need to be injected directly into the egg with ICSI (intra cytoplasmic s
injection) for fertilization to occur. Testicular sperm extraction is indicated fo
whom there is blockade in the epididymis very close to where it attaches to t
a blockade with in ducts that conduct sperm out of the testis.
IVF( in vitro fertilization)
In this induction of ovulation is done followed by aspiration of mature oocyte
ultrasonic guidance. 50000 selected sperms are used for insemination and at
stage, three emryo transfer into the uterine cavity 1 cm below the fundus is p
GIFT(gamete intra fallopian transfer technique)
It involves aspiration of oocytes following ovulation induction. These are mix
50,000 prepared sperms and transferred to ampullary portions of both the fa
tubes 4 cm from the fimbrial end. Thus MESA and TESA are both techniques o
aspiration but since the question specifically asks about aspiration directly fro
testes, TESA is the most appropriate ans here.
Of all the choices mentioned, MESA is a choice which can be answered Gene
ba choice between MESA and PESA is given, then PESA is the answer as PESA
simpler.
(a) PGE1
(b) PGI2
(c) PGA2
Your Response :
Correct Answer : d
Exp:
(Ref. Textbook of Obstetrics D.C. Dutta 6th Ed. 186)
Methods of termination of pregnancy:
Second Trimester (13-20 weeks):
1. Intrauterine instillation of hypertonic solutions
1. Intra amniotic 20% saline, 40% urea mannitol
2. Extra amniotic Ethacrydine lactate
2. Prostaglandins F2a and E2
3. Oxytocin infusion
4. Hysterotomy
(Q.82) A case of gestational trophoblastic neoplasia is detected to have lung metastasis. She should be st
as:
(a) Stage I
(b) Stage II
(c) Stage III
(d) Stage IV
Your Response :
Correct Answer : c
Exp: Anatomic staging for gestational trophoblastic tumors (GTT)-a FIGO
guideline
Stage I The lesion is confined to the uterus
Stage II The lesion spreads outside the uterus but is confined to the genital
organs
Stage III The lesion metastasizes to the lungs
Stage IV The lesion metastasizes to sites such as brain, liver and GI tract
(Q.85) Which of the following is the most common cause of persistent trophoblastic disease after H. Mol
evacuation?
(a) Choriocarcinoma
(b) Invasive mole
(c) Placental site trophoblastic tumor
(d) Residual Mole
Your Response :
Correct Answer : d
Exp: Upto 20% of women with H. Mole show persistence of tumor in uterus follow
evacuation.
15% persist as persistant or residual mole.
5% develop choriocarcinoma.
Trophoblastic tumors diagnosed for upto 6 months following an abortion or m
often
An invasive mole, but the one diagnosed after 6 months is usually choriocarc
It is to be noted that trophoblastic tumor developing after a full term pregna
always a choriocarcinoma.
(Q.86) Misoprostol has been found to be effective in all of the following, except
(a) Missed abortion
(b) Induction of labor
(c) Menorrhagia
(d) Prevention of postpartum hemorrhage (PPH)
Your Response :
Correct Answer : c
Exp: Studies in humans have shown that Misoprostol causes an increase in the fre
intensity of uterine contractions. Misoprostol administration has also been a
with a higher incidence of uterine bleeding and expulsion of uterine contents
(c) Thalassanemia
Exp:
Chorionic villous sampling (CVS) is generally performed at 10 to 13 weeks.
1. Second trimester amniocentesis - for genetic diagnosis is usually performed betw
20 weeks.
2. Early amniocentesis - this is performed between 11 and 14 weeks CVS fortropho
(derived embryologically from the same fertilized eggs as the fetus is usually done du
gestational weeks 11-13
The advantage of CVS is that the results are available early in pregnancy
Indications - Advanced maternal age (> 35 years), previous child with chromosomal a
abnormal parenteral karyotype, inversion, balanced or reciprocal
translocation, Robertsonian, foetal karyotyping for X-linked disorder, maternal anxiet
inborn error of metabolism.
Lipid storage disease
- Gaucher's disease, Fabry disease. Krabbe disease metachromaticleukodystrophy, Nie
syndrome mucolipidosis II sialidosis
Mucopolysaccharide disorder- Hunter, Hurler and Sanfilippo syndrome
Carbohydrate disorder - galactosemia, glyco eft storage (type n & IV) Aminoacidopath
Homocystinuria, cystinosis, tyrosinemia, maple syrup urine disease. Autosomal domin
disorders - adult polycystic kidney disease. myotonic dystrophy, Huntington's
chorea,osteogenesis imperfecta, retinoblastoma
Autosomal recessive disorders - a and thalassanemia, al antitrypsin deficiency,
CAH,phenylketonuria, cystic fibrosis sickle cell disease
Sex linked disorders - Duchenne's A & B, chronic granulomatous disease, Norrie's dise
retinitis pigmentosa
Relative contraindications
1. Vaginal bleeding or spotting
2. Extreme ante-or retroversion of the uterus
3. Patient body habitus precluding easy access to the uterus
4. Clear visualization of its content with ultrasound
5. Active infection.
(Q.97) Which one of the following is the best drug of choice for treatment of bacterial vaginosis during
pregnancy?
(a) Clindamycin
(b) Metronidazole
(c) Erythromycin
(d) Rovamycine
Your Response :
Correct Answer : b
Exp: Treatment of bacterial vaginosis:
Sensitive to metronidazole / clindamycin
Metronidazole use in the first trimester - no human evidence of terratogenesi
Topical therapy using vaginal gel is effective but may not reduce the risk of pr
delivery.
(Q.98) IUCD is absolutely contraindicated in all the following EXCEPT
(a) Undiagnosed vaginal bleeding
(b) Suspected pregnancy
(c) Congenital malformation of uterus
(d) PID
Your Response :
Correct Answer : c
Exp: Contraindication of IUCD
Absolute Relative
1. Suspected pregnancy 1. Anaemia
2. PID 2. Menorrhagia
3. Vaginal bleeding of 3. H/o PID since last pregnancy
undiagnosed
Aetiology 4. Pure lent cervical discharge
4. Cancer of the cervix, uterus or
adnexa and other pelvic 5. Distortions of the uterine cavity due t
tumours
5. Previous ectopic pregnancy congenital malformations, fibroids
6. Unmotivated person
(Q.99) Antenatal diagnosis can be made from all the following EXCEPT
(a) Foetal blood
(b) Maternal blood
(c) Amniotic fluid
(d) Decidua
Your Response :
Correct Answer : d
Exp: Foetal blood - for anemia, bleeding disorders, Rh disease Non-Immune hydro
fetalisMaternal blood - for alfa feto protein estimation for congenital disease
Amniotic fluid - assessing the fetal maturity, diagnosis of various malformatio
fetus and monitoring well being of the fetus in high risk, pregnancies.
Deciduae - the endometria lining of the uterus is called decidua during pregn
is shed after delivery, and no role for antenatal diagnosis.
(Q.100) Drug not used in the management of PPH?
(a) Mifepristone
(b) Misoprostol
(c) Oxytocin
(d) Ergotamine
Your Response :
Correct Answer : a
Exp: Drugs used in the management of Postpartum Hemorrhage
Oxytocin can be administered as a 5-U intravenous bolus, as 20 U in 1 L of N
intravenously run as fast as possible, or as 10 U intramyometrially with a spi
no immediate intravenous access is available.
The traditional second-line agent for uterine atony has been ergonovine (or
given as an initial dose of 100 or 125 mcg intravenously or intramyometriall
250 mcg intramuscularly.
The maximum total dose is 1.25 mg. Hypertension is a relative contraindicat
regions, the availability of ergot preparations has become problematic. Ever
should be made to secure supplies of this inexpensive and useful agent.
Many authorities now recommend the use of intramuscular carboprost as th
line agent when it is available. The recommended dose is 250 mcg intramus
intramyometrially, not to exceed 2 mg (8 doses). Asthma is a relative contra
Carboprost has been shown to be 80-90% effective in stopping PPH in cases
to oxytocin and ergonovine. Intramuscular administration of these agents is
recommended if the patient demonstrates evidence of shock because absor
be compromised.
Misoprostol may also become a valuable agent in the treatment of PPH. The
the drug and its heat stability (does not require refrigeration) makes it espec
appealing for use in the developing world. More trials are pending.
(Q.101) Carcinoma cervix extends to the lateral pelvic wall in which stage
(a) Stage I
(b) Stage II
(c) Stage III
(d) Stage IV
Your Response :
Correct Answer : c
Exp: Stage III B more precisely.
FIGO staging of cancer of cervix
Preinvasive carcinoma
Stage 0 carcinoma in situ
Invasive carcinoma
Stage 1
IA Carcinoma strictly extend to the cervix
Invasive cancer diagnosed only by microscopy.
All gross lesions, even with superficial invasions are stage m
IA1 Measured invasion of stroma no greater then 3 mm in depth and no wid
mm
IA2 Measured invasion of stroma greater than 3 nun in depth and no longer
in depth
and no wider than 7 mm
IB Clinical lesion confined to the cervix or preclinical lesions greater tha
IB1 Clinical lesion on greater than 4 cm
IB2 Clinical lesions greater than 4 cm
Stage II Carcinoma extends beyond the cervix but has not extended to the
the carcinoma involves of vagina but not as far as lower third
IIA No obvious parametrial involvement
IIB Obvious parametrial involvement
Stage III Carcinoma has extended either to the lower third of the vagina o
pelvic sidewall, all cases of hydronephrosis
IIIA Involvement of lower third of vagina, no extension to pelvic side wa
IIIB Extension on the pelvic wall and/or hydronephrosis or non function
Stage IV Carcinoma extended beyond the true pelvis or clinically involving
of the bladder or rectum
IVA Spread of growth ot adjacent organs
IVB Smead of growth to distant organs
(Q.102) The weight of the uterus at 8 weeks postpartum is
(a) 100 g
(b) 500 g
(c) 700 g
(d) 900 g
Your Response :
Correct Answer : a
Exp: The uterus weight about 1000 to 1200 gm immediately after delivery, As a r
involution, it decreases in weight to about 500 gm by one week, and to abou
the end of second week
At the end of 6 weeks its measurement is almost similar to that of the non-p
state and weight about 60 gm.
(Q.113) All of the following autoimmune disorder are more common in females except?
(a) ITP
(b) Multiple sclerosis
(c) Type I diabetes
(d) Scleroderma
Your Response :
Correct Answer : c
Exp: Most autoimmune disorders occur more commonly in women than in men;
include autoimmune thyroid and liver diseases, lupus, rheumatoid arthritis (
scleroderma, multiple sclerosis (MS), and idiopathic thrombocytopenic purp
However, there is no sex difference in the incidence of type 1 DM
(Q.114) Paramesonephric duct develop into:
(a) Vas deferens
(b) Seminal vesicle
(c) Ureter
(d) Uterus
Your Response :
Correct Answer : d
Exp: Male Female
Mesonephric duct Duct of epididymis Duct of epoophoron
(Wolffian duct) Ductus deferens Part of bladder and
urethra
Ejaculatory duct
Part of bladder and
prostatic urethra
Female Appendix of testis Uterine tube
(Paramesonephric or Prostatic utricle Uterus
Mullerian duct)
Vagina (?)
(Q.115) HRT is helpful in all of the following except:
(a) Vaginal atrophy
(b) Flushing
(c) Osteoporosis
(d) Coronary heart disease
Your Response :
Correct Answer : d
Exp: Consequence of HRT
1. Benefits
Decreased incidence of
a. Hip# b. Vertebral # c. Wrist # d. Colon cancer
Harms:
Increased incidence of
a. Coronary heart disease b. Thromboembolic events c. Breast
cancer d. Cholecystitis
2. Uncertain benefits
Prevention of dementia
(Q.116) Advantages of ultrasound nuchal translucency over biochemical screening for Downsyndrome in
(a) Uses transvaginal approach
(b) More consistent measurements than lab tests
(c) Better in multiple gestation
(d) Wide gestational age range
Your Response :
Correct Answer : c
Exp: The ultrasound nuchal translucency (NT) is now appreciated as a sensitive m
Down syndrome and other aneuploidies between 10 and 13 weeks. Outside
the NT disappears. Although some centers have had superb results, others h
done well. Blood free -hCG and PAPP-A in the first trimester, and double (AF
or triple (AFP, hCG, and estriol at 15 to 20 weeks) evaluations are statisticall
comparable. The combination of NT and first-trimester biochemistry will like
optimal approach. Biochemistry does not work well for multiple gestations.
can also detect structural anomalies, but often high-quality ultrasound servi
patients to travel long distances, whereas blood can be shipped from essent
anywhere to a competent lab.
(Q.119) Ramkali, a 37-year-old, is a case of polycystic ovary disease. LH/FSH estimation has to be done in
of the menstruation cycle
(a) 1-4 days
(b) 8-10 days
(c) 13-15 days
(d) 24-26 days
Your Response :
Correct Answer : b
Exp: Pre-ovulatory, LH, FSH level will need to be estimated
Menstrual 1-3 days
Preovulatory 8-10 days
Ovulatory -13-15 days
Post ovulatory or premenstrual- 26-28 days
(Q.120) 18year old girl presents with amenorrhoea, milk discharge, weight loss. Diagnosis is
(a) Pitutary Cancer
(b) Anorexia nervosa
(c) Hypothyroidism
(d) Hypohalamic cause
Your Response :
Correct Answer : a
Exp: Its tempting here to go for Hypothyroidism but that is usually associated wit
gain. However, pituitary tumors and craniopharyngiomas can cause increase
consequent galactorrheaweight loss attributed then to the malignant proc
(Q.121) Which of the following is the biochemical marker of choice from cholestatic jaundice of pregnanc
(a) Serum Bilirubin
(b) Bile acids
(c) Bile salts
(d) Alkaline phosphatase levels
Your Response :
Correct Answer : b
Exp: (Ref. Dutta Obstetrics 6th/ 291; H-17th/ 265)
Cholestasis of pregnancy occurs in the second and third trimesters and reso
delivery. Its cause is unknown, but the condition is probably inherited and c
can be triggered by estrogen administration. In cases of intrahepatic cholest
pregnancy,bile acids are cleared incompletely and accumulate in the dermis
causes intense itching. These patients develop pruritus in late pregnancy; th
characteristic skin changes or rashes except in women who develop excoria
scratching. Cholestyramine is often used in cases of cholestasis of pregnancy
serum bile salts and decrease pruritus. 16 weeks. In some cases, there can b
transient hepatic dysfunction. Intrahepatic cholestasis of pregnancy is chara
pruritus and/or icterus. Some women develop cholestasis in the third trimes
secondary to estrogen-induced changes. There is an accumulation of serum
which causes the pruritus. Liver enzymes are seldom elevated above 250 U/
(Q.122) In postmenopausal women, estrogen is metabolized mostly into:
(a) Estriol
(b) Estrone
(c) Estradiol
(d) Androstenedione
Your Response :
Correct Answer : b
Exp: Circulating estrogens In the ovulating woman are derived from two source
Sixty percent of mean estrogen formation during the menstrual cycle is in th
estradiol Q, formed primarily by ovaries.
Remainder is estrone formed mainly in extraglandular tissues from androste
After menopause extraglandular estrogen formation is the major pathway fo
synthesis Q Estrogen production by the menopausal ovary is minimal Plasma
estradiol are lower in postmenopausal women than levels of estrone The ra
peripheral formation of estrone increases in menopausal women so that est
production is only slightly less than it was prior to the menopause despite th
plasma androstenedione. The predominant estrogen formed is ESTRONE rat
estradiol. Q
(Q.125) Which of the following neoplasms has been associated with the use of oral contraceptives?
(a) Breast cancer
(b) Ovarian cancer
(c) Endometrial cancer
(d) Hepatic adenoma
Your Response :
Correct Answer : d
Exp: Beginning with high dose combination contraceptive pills used over 20 year
have been studied extensively for a possible association with neoplasia.
There is only scant evidence from this experience that use of oral contracep
increases the risk of any type of cancer.
Actually, the progestational component of combination pills (or progestin-o
may confer a protective effect against carcinoma of the breast and endome
avoiding ovulation may decrease the risk of developing ovarian carcinoma.
A slightly higher risk of cervical carcinoma was observed in some studies of u
contraceptives. These studies were not controlled, however, for confoundin
such as multiple partners or age at onset of sexual intercourse, and it is gen
believed now that any increased risk in contraceptive pill users would be att
these other factors and not the steroids themselves. Although the risk of de
benign liver adenoma is there with with the use of oral contraceptives.
(Q.126) A case of Gestational trophoblastic neoplasia belongs to high risk group if disease develop after
(a) Hydatidiform mole
(b) Full term pregnancy
(c) Spontaneous
(d) Ectopic pregnancy abortion
Your Response :
Correct Answer : b
Exp: Classification of gestational trophoblastic disease
H. mole - 1. Complete 2. Partial
Gestational trophoblastic tumors
Non metastatic
Metastatic - Low risk - no risk factors
High risk - any risk factors
Pyretherapy hCG level> 40,000 miu/mL
Duration> 4 months
Brain or liver metastasis
Prior chemotherapy failure
Antecedent term pregnancy
Hydatidiform mole (181 H &B) - It is regarded as a benign neoplasm of the c
a high malignant potential, It may result in one of the most fatal malignancie
and is also potentially the most curable due to recent advances in diagnosis
management.
(Q.127) Mrs Shikha, 50-yrs-old woman is diagnosed with cervical cancer. Which lymph node group would
involved in metastatic spread of this disease beyond the cervix and uterus?
(a) Common iliac nodes
(b) Parametrial nodes
(c) External iliac nodes
(d) Paracervical or ureteral nodes
Your Response :
Correct Answer : d
Exp: The main routes of spread of cervical cancer include vaginal mucosa, myom
paracervical lymphatics, and direct extension into the parametrium. The pre
lymph node disease correlates with the stage of malignancy Primary node g
involved in the spread of cervical cancer include the paracervical, parametri
obturator, hypogastric, external iliac, and sacral nodes, essentially in that or
commonly, there is involvement in the common iliac, inguinal, and paraaort
stage I, the pelvic nodes are positive in approximately 15% of cases and the
nodes in 6%. In stage II, pelvic nodes are positive in 28% of cases and paraao
in 16%. In stage III, pelvic nodes are positive in 47% of cases and paraaortic n
28%.
(Q.128) Normal stature with minimal or absent pubertal development may be seen in
(a) Testicular feminization
(b) Kallmann syndrome
(c) Pure gonadal dysgenesis
(d) Turner syndrome
Your Response :
Correct Answer : b
Exp: Testicular feminization is a syndrome of androgen insensitivity in genetic ma
characterized by a normal 46,X genotype, normal female phenotype during
tall stature, and normal breast development with absence of axillary and p
Breast development (gynecomastia) occurs in these males because high leve
circulating testosterone (which cannot act at its receptor) are aromatized to
which then acts on the breast. The external genitalia develop as those of a f
because testosterone cannot masculinize them, while the Mullerian structu
absent because of testicular secretion of Mullerian-inhibiting factor in utero
dysgenesis (e.g., 45,X Turner syndrome) is characterized by short stature an
pubertal development; in these girls the ovaries are either absent or streak
are nonfunctional. In either case, estrogen production is possible, and there
isosexual pubertal development does not occur. Mailman syndrome (hypog
hypogonadism) should be suspected in patients of normal stature with dela
absent pubertal development, especially when associated with the classic fi
anosmia. These individuals have a structural defect of the CNS involving the
hypothalamus and the olfactory bulbs (located in close proximity to the hyp
such that the hypothalamus does not secrete GnRH in normal pulsatile fashi
Other causes of minimal or absent pubertal development with normal statu
malnutrition; anorexia nervosa; severe systemic disease; and intensive athle
particularly ballet and running.
(Q.133) Which of the following cancer is commonly predisposed in the Lynch syndrome?
(a) Nonpolyposis colon cancer
(b) Ovarian cancer
(c) Endometrial cancer
(d) All of the above
Your Response :
Correct Answer : d
Exp: The Lynch syndrome occurs in families with an autosomal dominant mutatio
mismatch repair genes MLH1, MSH2, MSH6, and PMS2, which predispose to
nonpolyposis colon cancer as well as endometrial and ovarian cancer.
(Q.134) The most common pure germ cell tumor of the ovary is:
(a) Choriocarcinoma
(b) Dysgerminoma
(c) Embryonal cell tumor
(d) Malignant teratoma
Your
Response :
Correct
b
Answer :
Exp: (Ref. Shaws textbook of Gynacology-13th Edn-361)
Dysgerminoma:
It is the most common pure germ cell tumor of ovary.
It corresponds to Seminoma.
It is common under the age of 20.
It is usually unilateral.
It is neutral.
It secrets placental alkaline phosphatase.
It may be associated is hypoplasia or aplasia of part of
genital tract.
It is very radiosensitive.
It is potentially malignant with malignancy rate of 30-50%.
Endodermal sinus/yolk sac tumor is 2nd most common
germ cell tumor.
Embryonal cell tumor is rare.
(a) Submentobregmatic
(b) Submentovertical
(c) Mentovertical
(d) Occipitofrontal
Your Response :
Correct Answer : c
Exp: Various diameter:
Sub-occipitobregmatic diameter: Measured from below the occipital protub
the centre of the bregma or anterior fontanelle
Sub-occipitofrontal diameter: Measured from below the occipital protubera
centre of the frontal suture
Occipitofrontal diameter: Measure from the occipital protuberance to the g
root of the nose
Mentovertical diameter: Measured from the point of the chin to the highest
the vertex
Sub-mentovertical diameter: measured from the point where the chinjoints
the highest point of the vertex
Sub-mentobregmatic diameter: measured from the point where the chin joi
to the centre of the bregma
Biparietal diameter: The diameter between the two parietal eminences
Bitemporal diameter: The diameter between the furthest points of the coro
at the temples
(Q.140) In which of the following heart diseases is maternal mortality during pregnancy is found to be th
(a) Coarctation of aorta
(b) Eisenmengers complex
(c) Aortic stenosis
(d) Mitral Stenosis
Your Response :
Correct Answer : b
Exp: PULMONARY HYPERTENSION Maternal mortality in the setting of severe pu
hypertension is high, and primary pulmonary hypertension is a contraindica
pregnancy. Termination of pregnancy may be advisable in these circumstan
preserve the life of the mother. In the Eisenmenger syndrome, i.e., the com
pulmonary hypertension with right-to-left shunting due to congen-, ital abn
maternal and fetal death occur frequently. Systemic hypotension may occur
loss, prolonged Valsalva maneuver, or regional anesthesia; sudden death se
hypotension is a dreaded complication. Management of these patients, is ch
and invasive hemodynamic monitoring during labor and delivery is generally
recommended. In patients with pulmonary hypertension, vaginal delivery is
stressful hemodynamically than Cesarean section, which should be reserved
accepted obstetric indications.
(Q.143) All of the following drugs are commonly use in treatment of malignant germ cell tumor except:
(a) Bleomycin
(b) Etoposide
(c) Cisplatin
(d) Doxorubicin
Your Response :
Correct Answer : d
Exp: Most of the malignant germ cell tumors are managed with chemotherapy af
Regimens similar to those used in testicular cancer, such as BEP (bleomycin,
and cisplatin), with three or four courses given at 21-day intervals, have pro
long-term survival in patients with disease stages IIII. This regimen is the tr
choice for all malignant germ cell tumors except grade I, stage I immature te
where surgery alone is adequate, and perhaps early-stage dysgerminoma, w
surgery and radiation therapy are used.
(Q.144) Most preferable contraceptive device for a female suffering from Rheumatic Heart Disease who
completed her family is:
(a) IUCD
(b) Tubal ligation
(c) Norplant
(d) Barrier method
Your Response :
Correct Answer : b
Exp: Tubal ligation under local anaesthesia by minilap technique is the procedure
for permanent sterilization in a female with RHD who has completed her fam
The best time for the procedure is at the end of the first week in the puerpe
the heart is well compensated.
(Q.147) The most sensitive method for detecting cervical Chlamydia trachomatis infection is:
(a) Direct fluorescent antibody test
(b) Enzyme immunoassay
(c) Culture on irradiated MacConkey cells
(d) Polymerase chain reaction
Your Response :
Correct Answer : d
Exp: Nucleic acid probes have been developed for use in amplification assays suc
chain reaction and polymerase chain reaction (PCR). These tests are now the
sensitive chlamydial diagnostic methods available, being the first non-cultur
actually to surpass culture itself in sensitivity.
(Q.148) Pressure of normal uterine contractions isbetween 190-300. It is measured in terms of?
(a) Montevideo units
(b) Mm of Hg
(c) Cm of water
(d) Joules/kg
Your Response :
Correct Answer : a
Exp: (Ref. Williams obstetrics 22nd ed., p 466; Danforths Obstetrics and Gyneco
ed., ch 9)
The Montevideo unit =
The Average intensity of the uterine contractions X Number of contractions
minute period (expressed as mm Hg/10 min).
UTERINE ACTIVITY - STRENGTH
The strength of the contractions can only be assessed with the direct Intrau
Pressure Catheters (IUPC).
The normal baseline uterine pressure between contractions is approximatel
Abnormally high baseline pressures in excess of 20 mm Hg may result from
hyperstimulation or occasionally from overdistention of the uterus by exces
amnioinfusion, polyhydramnios, or fetal macrosomia.
During contractions, normal uterine pressure ranges from 30 to 80 mm Hg,
pressures in excess of 80 mm Hg may be observed during the second stage o
Many different quantitative approaches to uterine contractility have been
using IUPC technology.
(a) Face
(b) Vertex
(c) Aftercoming head in breech
(d) Brow
Your Response :
Correct Answer : d
Exp: Simpson forcepsare the most commonly used among the types of forceps a
elongated cephalic curve. These are used when there is substantialmolding,
temporary elongation of the fetal head as it moves through the birth canal
There is the ample pelvic curve in the single blade above and the cephalic cu
in the articulated blades below. The fenestrated blade and the wide shank in
the English-style lock characterize the Simpson forceps.
(Q.166) Highest rate of transmission of toxoplasmosis in pregnancy is:
(a) Puerperium
(b) 3rd trimester
(c) 2nd trimester
(d) 1 st trimester.
Your Response :
Correct Answer : b
Exp: About 1/3rd of all women infected with Toxoplasma gondii during pregnanc
the parasite to the fetus; the remainder will give birth to normal, un infecte
the various factors that influence fetal outcome, gestational age at the time
is the most critical. In pregnancy, if the mother becomes infected during the
trimester, the incidence of transplacental infection is lowest (about 15 %), b
disease in the neonate is most severe. If maternal infection occurs during th
trimester, the incidence of transplacental infection is greatest (65 %), but th
usually asymptomatic at birth.
(Q.169) All of the following are causes of intrauterine growth retardation, except
(a) Anemia
(b) Pregnancy induced hypertension
(c) Maternal heart disease
(d) Gestational diabetes
Your Response :
Correct Answer : d
Exp: Maternal causes of IUGR
Small women Maternal genetic and racial factors
Malnutrition during Anemia
pregnancy
Hypertension Antiphospholipid syndrome
Poor weight gain during Cyanotic heart disease
pregnancy
Malabsorption syndrome Alcohol drinking
Cigarette smoking Chronic renal failure
Chronic UTI
(Q.170) Which of the following cardiac disorder is very common in pregnancy?
(a) Supraventricular tachycardia
(b) Restrictive cardiomyopathy
(c) Ventricular ectopic
(d) Type II B block
Your Response :
Correct Answer : a
Exp: Supraventricular tachycardia is a common cardiac complication of pregnanc
Treatment is the same as in the nonpregnant patient, and fetal tolerance of
such as adenosine and calcium channel blockers is acceptable. When necess
electrocardioversion may be performed and is generally well tolerated by m
fetus.
(Q.173) Which of the following is the most common cause of postpartum hemorrhage mandating hystere
(a) Uterine atony
(b) Placenta previa
(c) Placenta accreta
(d) Genital tract laceration
Your Response :
Correct Answer : c
Exp: An abnormally adherent placenta, although an uncommon condition, assum
considerable significance clinically because of morbidity and, at times, mort
severe hemorrhage, uterine perforation, and infection. Abnormally adheren
placentation caused 65 percent of cases of intractable postpartum hemorrh
requiring emergency peripartum hysterectomy.
(Q.174) All the following are TRUE about Manning score EXCEPT
(a) Non-stress test
(b) Oxytocin challenge test
(c) Body movement
(d) Respiratory activity of a child
Your Response :
Correct Answer : b
Exp: Manning score - A method of biophysical scoring system based on multiple p
determined at real time ultrasound scanning forms the basis of the test.
It has been of great help in the management of high risk pregnancies includi
cases in determining the timing and mode of pregnancy termination, when
fetus seems to be in imminent jeopardy,
The parameter that constitute the biophysical profile include
(A) Non stress test (B) Fetal breathing (C) Fetal tone (D) Gross body moveme
Volume of amniotic fluid present.
Each parameter is given a score of 2 points, A score of 8 to 10 correlates we
good pregnancy outcome A score of less than 6 should be viewed with cauti
should be repeated within 24 to 48 hours
A score of less than 2 is associated with poor fetal outcome.
(Q.175) HIV transmission to the fetus from mother occurs most commonly at what gestational age?
(a) Ist trimester
(b) IInd trimester
(c) III trimester
(d) During birth
Your Response :
Correct Answer : d
Exp: Virologic analysis of aborted fetuses indicate that HIV can be transmitted to
early as the first and second trimester of pregnancy. However, maternal tra
the fetus occurs most commonly in the perinatal period. Studies indicate tha
relative proportions of mother-to-child transmissions were 2330% before b
65% during birth, and 1220% via breast-feeding.
(Q.176) A young girl presents with primary amenorrhoea, grade V thelarche, grade II pubarche and no ax
The most probable diagnosis is
(a) Testicular feminization
(b) Mullerian agenesis
(c) Turner syndrome
(d) Gonadal dysgenesis
Your Response :
Correct Answer : a
Exp: Testicular feminization syndrome - complete androgen resistance, presents
phenotypic young woman without sexual hair but with normal breast develo
primary amenorrhoea
Gonadal dysgenesis (Turner syndrome) 45X, 46XX characterized by primary
amenorrhea, sexual infantilism short stature, bilateral gonads streaks, in ph
woman
Mullerian agenesis - Congenital absence of the vagina, is the second to gona
dysgenesis as a cause of primary amenorrhoea, the height is normal and the
axillary and pubic hair, and habitus are feminine in character
(Q.177) A 15-year-old girl presents with a large unilateral adnexal mass and ascites. Which lesion is MOS
this patient?
(a) Immature teratoma
(b) Brenner tumor
(c) Granulosa cell tumor
(d) Serous adenocarcinoma
Your Response :
Correct Answer : a
Exp: Immature teratomas consist of fetal or embryonic tissue. These ovarian tum
most commonly in prepubertal adolescents. They grow rapidly and frequent
the peritoneum, resulting in ascites. Many may metastasize to distant sites.
(Q.178) All of the following may be observed in a normal pregnancy EXCEPT
(a) Fall in serum iron concentration falls
(b) Increase in serum iron binding capacity
(c) Increase in blood viscosity increases
(d) Increase in blood oxygen carrying capacity
Your Response :
Correct Answer : c
Exp: Physiological changes in termed physiological anemia of pregnancy, Iron
supplementation augments the RBC mass during pregnancy, There are distin
advantages, in the hemodilution, It lowers the viscosity of the maternal bloo
adequate gaseous exchange between the maternal and fetal blood, it also p
mother against the adverse effects of blood loss during the delivery Hemato
changes Increased
Plasma volume, RBC volume
Total haemoglobin
Plasma iron binding capacity
Iron absorption doubles
WBC counts
Factor I, VII, VIII, IX, X
Platelet survival time XI, XIII
Plasminogen levels fibrinogen
Albumin levels, ESR
Albumin: globulin ratio
Platelet count is generally normal, bleeding and clotting times remains norm
as factor II, V and XII remain unchanged
(a) Cytomegalovirus
Your Response :
Correct Answer : c
Exp:
Group A -hemolytic streptococci can cause puerperal or postoperative pelv
Outbreaks of puerperal fever are still reported on obstetric services, though
anywhere near the frequency of 50 years ago. When the disease does occur
source among the hospital personnel should be suspected. Group B -hemo
streptococci, which can also cause puerperal fever, have recently been reco
major cause of severe neonatal infection. The organism can be isolated from
cervixes of about 5% of all pregnant women; infection of the infant, which c
sepsis, occurs as the infant passes through the vagina T gondii, a protozoan
transmitted by flies from cat feces to human food. Thus, humans can becom
by consuming infected meat that is inadequately cooked or by coming in dir
with feces of an infected cat. Acute toxoplasmosis in a pregnant woman ma
a fulminantfetal infection; infected neonates may be born with microcephal
intracranial calcification, or other symptoms. An effective attenuated virus v
available for immunization against rubella. However, its use is generally con
for pregnant women and commonly is associated with development of arth
adults. Rubella syndrome has not been seen in fetuses when mothers are va
and vaccination can be considered if a pregnant woman is exposed to the vi
(Q.180) Formation of one of the following is essential for success of this instrument?
(a) Caput
(b) Chignon
(c) Phlegmon
(d) None of the above.
Your Response :
Correct Answer : b
Exp: CMI Tender Touch extractor cup.
Comparisons to other forms of assisted delivery
A. Positive aspects
An episiotomy may not be required.
The mother still takes an active role in the birth.
No special anesthesia is required.
The force applied to the baby can be less than that of a forceps delivery, and
no marks on the face.
There is less potential for maternal trauma compared to forceps and caesare
section.
B. Negative aspects
The baby will be left with a temporary lump on its head, known as a chignon
There is a possibility of cephalohematoma formation, or subgaleal hemorrha
(Q.183) The following surgical procedure is done in which phase of the menstrual cycle?
(Q.185) A patient underwent surgery for ovarian mass diagnosed on ultrasound. The tumor markers wer
At laparotomy peritoneal washings were taken and after thorough inspection of
abdomen Ipsilateral salpingo-oophorectomy was performed. The lateral end of the pedicle is for
(Q.193) A patient with severe pregnancy induced hypertension presents with cardiac failure after 1 week
uneventful normal vaginal delivery. The chest roentgenogram demonstrates enlargement of the
silhouette, suggestive of Dilated cardiomyopathy. Themortality in this condition is ?
(a) 10%
(b) 30%
(c) 50%
(d) 70%
Your Response :
Correct Answer : a
Exp: Cardiac dilatation and CHF may develop during the last trimester of pregnan
6 months of delivery. The cause is unknown, although inflammatory myocar
immune activation, and gestational hypertension have all been incriminated
patient who develops peripartum cardiomyopathy typically is multiparous a
years, although the disease may be found in a wide spectrum of patients.
The mortality rate of this disorder is around 10%.
The prognosis is related to whether the heart size returns to normal after th
episode of CHF. If it does, subsequent pregnancies may sometimes be tolera
with an increased risk of recurrent CHF; if the heart remains enlarged, and/o
ejection fraction (EF) remains depressed after 6 months, the prognosis is po
further pregnancies frequently produce additional myocardial damage, ultim
leading to refractory CHF. Patients who recover from peripartum cardiomyo
should be encouraged to avoid further pregnancies, particularly if LV dysfun
persists.
(Q.194) Cause of post-menopausal bleeding is:
(a) Arrhenoblastoma
(b) Cystadenoma
(c) Granulosa cell tumour
(d) Hilus cell tumour
Your Response :
Correct Answer : c
Exp: Another frequently asked ovarian tumour to cause post-menopausal bleedi
theca cell tumour.
Both granulosa cell tumour and theca cell tumour are feminising sex-cord
tumours of the ovary.
(Q.197) Which surgical procedure has the highest incidence of ureteric injury?
(a) Vaginal hysterectomy
(b) Abdominal hysterectomy
(c) Wertheims hysterectomy
(d) Anterior colporrhaphy
Your Response :
Correct Answer : c
Exp: Wertheims requires dissection of the periureteral tissues and removing the
surrounding the course of the ureter. This can devascularize the ureter caus
fistulas. The next most common cause of ureteric injury is abdominal hyster
Another common cause ( and generally missed ) is the entrapment of the u
repairing high tears in the vaginal vault during cervical or vaginal lacerations
(Q.198) Most common cause of acute cervicitis is:
(a) E. Coli
(b) Chlamydia
(c) Pseudomonas
(d) Gonococcus
Your Response :
Correct Answer : d
Exp: Causes of acute cervicitis are : 1. Gonorrhoea 2. Septic
abortion 3.Puerperal Sepsis.