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BC-3300
Service Manual
Copyright
2008-2011 Shenzhen Mindray Bio-medical Electronics Co., Ltd. All rights Reserved.
For this Service Manual, the issued Date is 2011-02 (Version: 1.0).
Mindray intends to maintain the contents of this manual as confidential information. Disclosure
of the information in this manual in any manner whatsoever without the written permission of
Mindray is strictly forbidden.
All information contained in this manual is believed to be correct. Mindray shall not be liable for
errors contained herein nor for incidental or consequential damages in connection with the
furnishing, performance, or use of this manual.
Mindray is responsible for safety, reliability and performance of this product only in the
condition that:
the electrical installation of the relevant room complies with the applicable national
I
and local requirements;
Be sure to operate the analyzer under the situation specified in this manual;
otherwise, the analyzer will not work normally and the analysis results will
be unreliable, which would damage the analyzer components and cause
personal injury.
II
Warranty
Exemptions
Mindray's obligation or liability under this warranty does not include any transportation or other
charges or liability for direct, indirect or consequential damages or delay resulting from the
improper use or application of the product or the use of parts or accessories not approved by
Mindray or repairs by people other than Mindray authorized personnel.
any Mindray product which has been subjected to misuse, negligence or accident;
any Mindray product from which Mindray's original serial number tag or product
identification markings have been altered or removed;
Return Policy
Return Procedure
In the event that it becomes necessary to return this product or part of this product to Mindray,
the following procedure should be followed:
1. Obtain return authorization: Contact the Mindray Service Department and obtain a
Customer Service Authorization (Mindray) number. The Mindray number must appear
on the outside of the shipping container. Returned shipments will not be accepted if
the Mindray number is not clearly visible. Please provide the model number, serial
III
number, and a brief description of the reason for return;
2. Freight policy: The customer is responsible for freight charges when this product is
shipped to Mindray for service (this includes customs charges);
3. Return address: Please send the part(s) or equipment to the address offered by
Customer Service department.
Company Contact
Phone: 0049-40-2513175
Fax: 0049-40-255726
IV
Table of Contents
Copyright I
Intellectual Property Statement I
Responsibility on the Manufacturer Party I
WarrantyIII
Exemptions III
Return PolicyIII
3 Upgrade 3-1
3.1 Software upgrade 3-1
5 Fluidic System 51
5.1 Fluidic Components and Functions 5-1
5.2 Reagent Consumption 5-2
5.3 Sample Dilution Flowchart 5-3
5.4 Introduction of Fluidic Channels 5-5
5.5 Introduction of Basic Sequence 5-6
1
Table of Contents
7 Servicing 7-1
7.1 General 7-1
7.2 Disassembling the Panels 7-2
7.3 Replacing the Hardware parts and Cable connection 7-6
7.4 Replacing the Power Supply Assembly 7-16
7.5 Replacing the Display Assembly 7-17
7.6 Replacing the Touch Screen 7-18
7.7 Replacing the Recorder Assembly 7-19
7.8 Replacing the valve, pumps, and other liquid system parts 7-20
7.9 Replacing the counting bath assembly 7-29
7.10 Replacing the syringe assembly 7-35
7.11 Replacing the sample probe assembly 7-37
7.12 Replacing the sample compartment assembly 7-47
7.13 Replacing the start key 7-56
7.14 Micro-Switch Assembly Replacement 7-57
7.15 Fluidic Support-bracket Assembly 7-58
7.16 Front Panel Detection Assembly 7-59
7.17 Ambient Temperature Sensor Replacement 7-60
7.18 Cap Assembly 7-61
7.19 Gain Adjustment 7-62
7.20 Motor Type, Position and Different Application List 7-64
7.21 The Check List After Material Replacement 7-64
10 Appendices A-1
2
1 Using This Manual
This chapter explains how to use this service manual. This manual states in detail the way to
service the BC-3600 and BC-3300 analyzers. Before servicing the BC-3600 and BC-3300,
read and understand the manual carefully for servicing the equipment properly and for your
safety.
This manual is to be used in conjunction with the operator's manuals of BC-3600 and
BC-3300.It does not contain information and procedures already covered in the operator's
manuals of BC-3600 and BC-3300.
Be sure to operate and service the analyzer strictly as instructed in this manual and the
operator's manuals.
1-1
Using This Manual
1.1. Scope
1.2. Introduction
This manual comprises 9 chapters and 6 appendices. Refer to the table below to find the
information you need.
1-2
Using This Manual
This manual uses certain typographical conventions to clarify meaning in the text:
Format Meaning
all capital letters enclosed in [ ] indicate a key name (either on
[]
the pop-up keyboard or the external keyboard)
letters included in " " indicate text you can find on the screen
of BC-3600 and BC-3300
italic letters indicate titles of the chapters that are referred
to
"Menu"
the " " button on the screen.
All illustrations in this manual are provided as examples only. They may not necessarily reflect
your analyzer setup or data displayed.
1-3
Using This Manual
1.5. Symbols
You may find the following symbols on the analyzer, reagents, controls or calibrators.
BIOLOGICAL RISK
HIGH VOLTAGE
ALTERNATING CURRENT
1-4
Using This Manual
BATCH CODE
USE BY (YYYY-MM-DD)
SERIAL NUMBER
MEASUREMENT AUTHORIZATION
SYMBOL
DATE OF MANUFACTURE
MANUFACTURER
THIS ELECTRO-INFORMATIONAL
PRODUCT CONTAINS CERTAIN
POISONOUS OR HARMFUL SUBSTANCE.
ITS ENVIRONMENTAL LIFT TIME IS 20
YEARS. IT CAN BE USED WHTHIN 20
YEARS, AFTER THAT IT SHALL BE
RECYCLED.
Be sure to observe the following precautions for the safety of patients and operators when you
are servicing the analyzer.
When servicing the analyzer, be sure to turn off the power. Servicing the
analyzer when it is on may bring risk of electric shock or damage to
electronic components.
Connect the analyzer to a socket having sole fuse and protective switch. Do
1-5
Using This Manual
not use the same fuse and protective switch with other equipment (e.g. life
supporting equipment). Otherwise, the equipment failure, over current or
impulse current that occurs at the startup moment may lead to tripping.
To prevent personal injury during maintenance, keep your clothes, hairs and
hands from the moving parts, such as sample probe, clipper and piercer.
The reagents are irritating to eyes, skin and mucosa. Wear proper personal
protective equipment (e.g. gloves, lab coat, etc.) and follow safe laboratory
procedures when handling them in the laboratory.
If the reagents accidentally spill on your skin, wash them off with plenty of
water and if necessary, go see a doctor; if the reagents accidentally spill into
your eyes, wash them off with plenty of water and immediately go see a
doctor.
When the front cover is open, be sure to close the sample compartment door,
or the sample compartment assembly or the front cover may be damaged.
When transporting the analyzer, the screw at its bottom may scratch your
hands, please exercise caution or wear gloves.
1-6
Using This Manual
All the analyzer components and surfaces are potentially infectious. Take
proper protective measures for operation or maintenance.
The sample probe tip is sharp and may contain biohazardous materials.
Exercise caution to avoid contact with the probe when working around it.
Figure 1-1
1-7
Using This Manual
Warning, potential biohazardous risk.
1-8
Using This Manual
Figure 1-2
Warning, the sample probe is sharp and may contain biohazardous substance. Exercise
caution to avoid contact with the probe when working around it.
1-9
Using This Manual
Figure 1-3
Warning, make sure the protective cover is properly installed before operation.
Warning
Do not put your hands close to the sampling assembly when the analyzer is running.
Warning, the sample probe is sharp and may contain biohazardous substance.
Exercise caution to avoid contact with the probe when working around it.
Warning, the sample probe is sharp and may contain biohazardous substance. Exercise
1-10
Using This Manual
caution to avoid contact with the probe when working around it.
Figure 1-4
Warning, risk of electric shock.
1-11
Using This Manual
1.6. Definitions
There are two sampling mode: open vial mode and closed tube mode.
The operator presents the tube or open vial evacuated collection tube containing blood sample
to the sample probe, and press the "Aspirate" key to collect sample.
The analyzer of which the sampling mode is open vial is called open vial analyzer.
The operator puts the capped tube into the sample compartment, the analyzer collects sample
1-12
2 Analyzer Structure
Voltage (100V-240V)10%
Input Power 180 VA
Frequency 50/601Hz
2-1
Analyzer Structure
Height
Depth
Width
2.2.4 Throughput
The throughput of open vial analyzers under whole blood mode is no less than 60 samples per
hour; the time needed for the analysis of one sample is no more than 60s (the sample dilution
time is not included for predilute mode).
The throughput of closed tube analyzers under whole blood mode is no less than 60 samples
per hour; the time needed for the analysis of one sample is no more than 60s (the sample
dilution time is not included for predilute mode).
2.2.5 Parameters
The analyzer determines 21 parameters (WBC, RBC, PLT, HGB, etc.) and 3 histograms
(WBC, RBC and PLT) of blood samples.
2-2
Analyzer Structure
Table2-4Table of histograms
Parameter Requirement
0.3 10 / L
9
WBC
12
RBC 0.03 10 / L
HGB 1g/L
HCT 0.5 %
9
PLT 5 10 / L
2-3
Analyzer Structure
2.2.6.2 Reproducibility
Run the sample meeting the reproducibility requirements for 10 consecutive times on the
analyzer, then calculate the CV(%) and SD, the requirements in Table 2-6 and 2-7 must be
met.
WBC
4.0 ~ 6.9 10 / L
9
3.5
3.50 ~ 6.50 10
12
/L 2.0
RBC
100 ~ 180 g/L 1.5
HGB
70.0~ 110.0 fL 0.5
MCV
4.0
150 ~ 500 10 / L
9
PLT 9
5.0
100~149 10 / L
3050% 3.0
HCT
Lymph% 2050 1.5SD
2-4
Analyzer Structure
12 12 12
RBC 08.0010 /L 0.0510 /L or 5 0.0510 /L or 5
HGB 0280g/L 2g/L or 2 2g/L or 3
9 9 9
PLT 0100010 /L 1010 /L or 10 1010 /L or 10
9
1001300010 /L 12 20
4% (HCT value) or 6% /
HCT 060%
(deviation)
Test suggestion:
12
When testing RBC linearity range 7.008.0010 /L, use sample of which the HCT 60%;
9
When testing PLT linearity range 1001300010 /L, use sample of which the RBC 6.
2.2.6.4 Carryover
Test method: mix the high value sample (centrifuged high value control or specialized high
value linearity control) within the range of Table 2-9, test the sample for 3 consecutive times,
and then mix and test the low value sample (diluted low value control, dilution rate 1:10) within
the range of Table 2-9 for 3 consecutive times, then calculate the carryover. The requirements
in Table 2-10 must be met.
Table 2-9 Requirements on high and low value controls of carryover calculation
Parameter Carryover
WBC 0.5
RBC 0.5
HGB 0.5
PLT 1.0
2.2.7 Functions
2.2.7.1 Startup and Shutdown
When starting up the analyzer, initialization will be performed to prepare the analyzer for
counting. Different startup cleaning sequence will be performed base on the latest shutdown
status to ensure the success of background counting. The analyzer provides the function to
skip fluidics initialization to the users of service level and above.
2-5
Analyzer Structure
2-6
Analyzer Structure
2-7
Analyzer Structure
2.3.2 Reagents
In order to ensure the accuracy of analysis results, you shall use the reagents, controls
and calibrators specified by Shenzhen Mindray Bio-medical Electronics Co., Ltd. For
details, refer to Table 2-12.
Item Name
2-8
Analyzer Structure
2-9
Analyzer Structure
2-10
Analyzer Structure
2.4.2 Password
The login service ID is "Service", password is "s 3600!", case sensitive and space required.
With service access level, you can perform all functions that are open to common users and
some other special functions:
1 Transfer factor calibration function:
1 Under whole blood mode, click "Menu">"Calibration">"Calibrator", finish the
calibration successfully, exit and save the calibration factors.
2 Click "Menu">"Calibration">"Transfer factor" to enter the screen in Figure 2-8,
run the sample used in the above step for 5 consecutive times under whole blood
mode, check if CV(%) meets the requirements in Table 2-13; if not, cancel a abnormal
result and calculate again (results of at least 5 analyses required), then check if the
requirements in Table 2-13 are met.
2-11
Analyzer Structure
3 Click the "Predilute" button to switch to the screen of predilute mode, as Figure 2-9
shows;
2-12
Analyzer Structure
4 Click the Diluent icon, perform diluent dispensing for 7 consecutive times;
5 Add 140l of calibrator in to the diluent, mix thoroughly and then run the mixture for
more than 5 times under the predilute mode. The CV(%) values must meet the
requirements of Table 2-14, and the calibration factors are within the range [0.75,
1.25].
Table 2-14 Range of CV value under predilute mode
Param WBC RBC HGB MCV PLT
eter
CV 4.0% 2.0% 2.0% 1.5% 8.0%
value
2 The gain of WBC and RBC can be adjusted, see Figure 2-10;
2-13
Analyzer Structure
3 In the service setup screen, you can set up languages, software upgrade, volume of the
volumetric tube, analyzer SN, sample probe positioning adjustment, background
information monitoring (auto adjust of analysis time), rinse photocoupler calibration, etc.
The following section will introduce the sample probe positioning adjustment and rinse
photocoupler calibration functions.
1) Sample probe positioning adjustment:
Tool: the positioning calibration clamp of sample probe sampling position
Procedure: open the cover as Figure 2-11 shows, open the sample compartment door,
take out the tube holder adapter from the compartment, put the positioning calibration
clamp to the sample compartment, and then close the compartment door.
2-14
Analyzer Structure
2-15
Analyzer Structure
2-16
Analyzer Structure
Click "Start" and then click "OK", the dialog box "Priming diluent" will pop up, then an
instruction message will be displayed, use the slot-headed screwdriver to rotate the
potentiometer VR1(RINSE) on the drive board (see Figure 2-15) counter-clockwise
until the D22 (RINSE-LED) turns on. Note: continue to rotate the VR1 for 180 degrees
after the D22 turns on.
Figure 2-15
Connect the connector of the rinse pickup tube to the fitting on the back panel of the
analyzer, click "OK" and then click "Finish", the dialog box "Priming rinse" will pop up,
check the calibration status then: if "Pass" is displayed (see Figure 2-16), that means
the calibration succeeded. The reference voltage and measured voltage are displayed
as "Reference(V)" (1.8-3.0V) and Actual(V) in Figure 2-16.
"PASS"
displayed
Figure 2-16
Note:
Rotate the VR1 for 180 degrees more after the D22 turns on, and make sure the LED
is illuminated.
Do not modify the value in the edit box Max(V), Min(V) and Factor(V);
If calibration cannot be done successfully due to the quality of the photocoupler itself
and the PCBA or photocoupler must be replaced, then recalibration is needed. The
dialog box "Remove the Rinse tube from the container and press [OK] to continue."
will pop up, press [OK] to drain the tubing; then do as instructed by the prompt - "1.
Adjust rinse photocoupler potentiometer till the RINSE-LED turns on; 2 Put the Rinse
tube into the container and press [OK]to close the dialog box; 3. Click [Finish] button"
to prime rinse after calibration is done.
2-17
Analyzer Structure
Figure 2-18
1) If a new CF card is replaced, follow the guidance to select "Restore" and restore the
critical data to the CF card.
2) If a new data board is replaced, follow the guidance to select "Backup" and backup the
data to the data board.
3) If only the drive board is replaced, no special action shall be taken, the data will not be
2-18
Analyzer Structure
lost.
6 Users of the service level can export special information, see the figure below.
Figure 2-19
2-19
Analyzer Structure
2-20
3 Upgrade
3.1.1 Preparation
1The whole software upgrade procedure will take about 6~11mins.
Figure 3-1
3Log in the BC-3600 with Service Engineer username and password.
4Run Setup Service Setup Setup Start Upgrade (see figure 3-2), and then click Yes
in the dialog box (see figure 3-3).
3-1
Upgrade
Figure 3-2
Figure 3-3
NOTES:
1Make sure the UBS storage connected well to the USB interface of the Analyzer.
2After you click Yes to start the upgrade, the system will start to read and analyze the
configuration in the UBS storage and this will last for about 1min. Please wait for the pop-up
upgrade confirmation dialog box.
3Do NOT remove the USB flash disk during the upgrade.
3-2
Upgrade
5software upgrade.
1) See the following software upgrade screen:
Figure 3-4
2) Click the Upgrade button to start the upgrade. You will see the upgrade preparation dialog.
(See figure 3-5)
Figure 3-5
3) The upgrade preparation lasts for about 1 min, after that, you will see the upgrade confirm
dialog. (See figure 3-6)
Figure 3-6
4) Click Yes to start the upgrade. (See figure 3-7)
3-3
Upgrade
Figure 3-7
5) You may need to restart the instrument for several times during the upgrade. (See figure
3-8)
Figure 3-8
6) Upgrade succeeded. (See figure 3-9)
Figure 3-9
7) Upgrade failed. (See figure 3-10)
3-4
Upgrade
Figure 3-10
8) After you finish all the process, please restart the instrument. (See figure 3-11)
Figure 3-11
6After upgrade finished, log in with the service engineer username and password. Run
Service Version to check upgrade items. (See figure 3-12)
Figure 3-12
3-5
Upgrade
Figure 3-13
2If upgrade failed, export the debug data. (See figure 3-14)
Figure 3-14
3-6
4 Mechanical System
4-1
Mechanical System
4-2
Mechanical System
4-3
Mechanical System
4-4
Mechanical System
4-5
Mechanical System
4-6
Mechanical System
4-7
5 Fluidic System
5.1.3 Pump
Gas pump (GP): provide pressure to the vacuum chamber for generation of bubbles.
Waste pump (LP): draining probe wipe, WBC bath, RBC bath and vacuum chamber
and building vacuum.
5.1.4 Syringes
Sampling syringe (Asp-Syringe): full measuring range is 100l; aspirating fixed
quantity of sample, dispensing the sample and aspirating the diluted sample again.
Diluent syringe (Dil-Syringe): full measuring range is 10ml; dispensing fixed quantity
of diluent to WBC and RBC bath, providing diluent to probe wipe.
Lyse syringe (Lyse-Syringe): full measuring range is 2.5ml, motivated by the same
motor with the diluent syringe; dispensing lyse.
5.1.5 Valves
Fluid valve and magnetic valve: diaphragm form, controlled by electric magnetic
power. Controlling the directional flow of fluid or air.
5.1.6 Baths
WBC bath: composed of front bath, back bath and aperture. Providing room for the
mixing of WBC sample; measuring HGB and WBC.
RBC bath: composed of front bath, back bath and aperture. Providing room for the
mixing of RBC sample; measuring RBC/PLT.
Vacuum chamber: build and store stable vacuum for the impedance counting of WBC
and RBC, clean the back baths and drain volumetric tubes.
Pressure chamber: build and store stable pressure for generation of bubbles in all
baths.
5-1
Fluidic System
RBC volumetric tube: its volume is 200ul, measuring volume of the RBC sample to
be analyzed.
5.1.8 Filters
Filter of WBC volumetric tube: filtrate the air entering the WBC volumetric tube.
Filter of RBC volumetric tube: filtrate the air entering the RBC volumetric tube.
Customized filter: filtrate the impurities and scraps from the probe wipe.
Filter of the isolation chamber: filtrate the impurities and scraps from the baths.
There are four counting modes: OV-WB, OV-PD, CT-WB and CT-PD. See Table 5- 1 for the
reagent volume consumed in one analysis cycle of a sample.
Reagent consumed in
one analysis cycle of a
Item Name
sample
Whole blood Predilute
Diluent M-30D DILUENT 28mL 28mL
5-2
Fluidic System
5-3
Fluidic System
5-4
Fluidic System
5-5
Fluidic System
5-6
Fluidic System
? ?
RBC WBC
Blood
Diluent
sample
a) b)
?
? ? ?
?
RBC WBC RBC WBC
First Secon
dilutio d
n dilution
c) sampl sample
d)
e
Figure 5- 3 Sampling and dispensing procedure
5-7
Fluidic System
V01 V01
Diluent Diluent
10ml 10ml
100ul 100ul
V19 V19
Waste Waste
a) Wash exterior wall of b) Wash interior wall of
sample probe sample probe
5-8
Fluidic System
V01
Diluent
V04
V02 V03
10mL
2.5mL
(SR1) SR3
WBC
bath Lyse
Isolation
chamber
V16
Waste
V01
Diluent
V04
V02 V03
10mL
2.5mL
(SR1) SR3
WBC
bath lyse
5-9
Fluidic System
V05 V07
Atmosp WBC
heric bath
pressure
Volumetric
board
Pressure V14
Rinse
Vacuum
chamber
V09
Isolation
V10 chamber
V18
V16
Waste
Figure 5- 7Fluidic passages of washing WBC back bath and volumetric tube
5-10
Fluidic System
Second aspiration in the WBC bath: the sample probe descends to the WBC
bath and aspirates 34 ul of fluid at 19.9~21s.Valve 17 opens, and the RBC bath
is drained.
The sample probe ascends: when the second aspiration finishes, the sample
probe ascends to home position with its exterior wall washed; besides, 1800 ul
of diluent is added to the RBC bath at 24.5~25.5s.
Adding sample to RBC bath, and lyse to WBC bath: the sample probe moves to
the RBC bath and descends into the bath; the lyse syringe dispenses 350ul of
lyse into the WBC bath, the fluidic passage is indicated in Figure 5- 8; the diluent
syringe discharges 800 ul of fluid (mixture of first dilution sample and diluent)
through the sample probe. Valve 10 opens at 26.65~27.25s, the pressure
chamber blows bubbles into the WBC bath; then a bubble that can last for 0.05s
is blowed into the WBC bath, and 3 bubbles are blowed into the RBC bath in
turn; Finally, the sample probe restores to the original position with its exterior
wall washed.
V03
2.5mL
(SR1)
WBC
bath
Lyse
Other actions finished during the sample dispensing, dilution and mixing
procedure:
Build the vacuum needed for analysis, total time consumed is 7.9s;
Build the pressure needed for bubble generation;
RBC aperture voltage inspection: same as WBC aperture voltage inspection;
The sample compartment door opens at 12s to prepare for the next analysis
cycle.
Analysis
The actions are:
Measuring volume of volumetric tube: valve 7 opens after WBC bubbling
finishes for a while and valve 8 opens after RBC bubbling finishes for a while,
the fluidic passage is indicated in Figure 5- 9; the closing of valve 7 and valve 8
is finished by the ending cleaning cycle started when the WBC and RBC down
photocouplers are triggered.
5-11
Fluidic System
V05 V07
V14
Vacuum V15
chamber Rinse
V18
Waste
5-12
Fluidic System
with those of the closed tube sequence, therefore the whole blood analysis sequences of open
vial models will not introduced in detail.
5-13
Fluidic System
5-14
Fluidic System
5-15
Fluidic System
dispense fluid at a higher speed so that the bubbles in the sampling tube can be
removed effectively.
6 The sample probe dispenses fluid in the WBC bath: removing all the bubbles in
the sampling tube.
7 Cleaning the two baths: cleanser volumes of WBC bath 4ml, 4.6ml, 5.5ml;
cleanser volumes of RBC bath 4ml, 4ml, 5ml, generating bubbles during the
cleaning process to strengthen the cleaning effect.
8 Emptying WBC, RBC baths and the back baths, switching among valve 16 ,17, 7
and 8 to strengthen the cleaning effect.
Startup after abnormal shutdown
This sequence includes the troubleshooting sequence 1, fluidics initializing sequence and
startup sequence after normal shutdown.
1. Troubleshooting sequence 1, refer to the corresponding section.
2. Fluidics initializing sequence, refer to the corresponding section.
3. Startup after normal shutdown
5-16
Fluidic System
residual sample in the fluidic components, so the exterior and interior walls of
the sample probe must be cleaned repeatedly by fluid discharging of the
sample probe and probe wipe.
2 0.5ml of lyse is discharged to make sure the tube mouth is filled with reagent.
3 Push back 200ul of diluent to the cleanser tube to wash off the cleanser at the
closed end of valve 12.
4 Remove the bubbles in the sampling tube through fluid discharging for multiple
times.
5 Clean the two baths repeatedly to remove the possible residual sample.
6 Zapping for 4s to avoid clogging.
7 Wash tubes of the back baths twice to remove the residual sample in the tubes
or volumetric tubes.
5-17
Fluidic System
6. Wash the tubes of the back baths. Empty the vacuum chamber and release vacuum.
5.5.4.2 Zapping sequence
Introduction:
1. Build vacuum in the vacuum chamber, zap the two baths for 4s.
2. Drain the two baths and add 3.5ml of fluid in the two baths respectively.
3. Wash the tubes of the back baths. Empty the vacuum chamber and release vacuum.
5.5.4.3 Flushing sequence
Introduction:
1 The flushing sequence is almost the same as the unclogging sequence, only it involves no
zapping operation.
5.5.4.4 Draining sequence of the baths
Introduction:
1 Drain the two baths for 3s.
5.5.4.5 Priming sequence of the baths
Introduction:
1. Drain the two baths and add 3.5ml of fluid in the two baths respectively.
2. The function is activated after the baths are drained. The baths may need to be
serviced during the draining process, the tubes of the back baths need to be washed.
3. Drain the vacuum chamber and release vacuum.
5.5.4.6 Cleaning sequence of the baths
Introduction:
1. 4.5ml of fluid is added to the two baths respectively, and bubbles are generated to
strengthen the cleaning effect.
2. Drain the two baths and add 3.5ml of fluid into the two baths respectively, open valve
18 and the fluidic pump for a while to release pressure in the pressure chamber.
5.5.4.7 General probe cleanser soak sequence
This sequence includes soaking sequence and the cleaning sequence after soaking.
Soaking procedure:
5-18
Fluidic System
Introduction: the soaking process consists of three steps. Step 1: soak the WBC aperture
and interior wall of the sample probe with 100% probe cleanser. Step 2: soak the WBC and
RBC front/back baths with 30.77% and 38.46% probe cleanser respectively. Step 3: soak the
WBC and RBC front/back baths with 26.32% and 21.05% probe cleanser respectively. The
operations are:
1. The sampling syringe withdraws for 2ul to form a separating air bar.
2. The sample probe aspirates 1.8ml of probe cleanser, the two baths are drained,
the sample probe ascends with its exterior wall washed.
3. The sample probe dispenses 1ml of probe cleanser into the WBC bath to form
100% probe cleanser.
4. The sample probe dispenses 2.6ml of mixture of probe cleanser and diluent into
the RBC bath to form the high concentration compound (30.77%) for the first
soak.
5. The sample probe dispenses 1.6ml of diluent into the WBC bath to form the high
concentration compound (38.46%) for the first soak.
5-19
Fluidic System
6. After soaking for about 2 minutes, dispenses 1.2ml of diluent to the two baths to
dilute the probe cleanser, which will be used for the long term soaking of the front
and back baths (WBC:26.32%; RBC:21.05%).
7. Build vacuum and aspirate fluid: aspirate for 6s from the WBC bath, the volume
aspirated is about 232ul; aspirate for 8s from the RBC bath, the volume aspirated
is about 236ul; When the aspiration finishes, release the vacuum in the vacuum
chamber.
8. Meanwhile, the sample probe aspirates 50ul of fluid from the RBC bath for
soaking of the interior wall of sample probe and the tube.
9. Soak the tubes for 2 minutes and then start the cleaning procedure.
Cleaning procedure:
5-20
Fluidic System
Introduction: the front and back baths, sampling tube, waste valve shall be cleaned to remove
residual probe cleanser.
1. Add probe cleanser to the WBC bath; when draining the WBC bath, switch on/off
valve 16 for multiple times to soak the waste valve with probe cleanser (for about
5s) to remove residual probe cleanser.
2. Add probe cleanser to the RBC bath; when draining the RBC bath, switch on/off
valve 17 for multiple times to soak the waste valve with probe cleanser (for about
5s) to remove residual probe cleanser.
5-21
Fluidic System
3. The sample probe dispenses 7.8ml of probe cleanser to the RBC bath to clean
the sampling tube and remove bubbles in the tubing.
4. Discharge fluid to the probe wipe twice, meanwhile the sample probe ascends to
avoid residual probe cleanser on the exterior wall of the sample probe or in the
probe wipe.
5. Build vacuum, wash tube of the back bath, switch on/off valve 7 and 8 for
multiple times.
6. Empty the vacuum chamber, switch on/off valve 18 for multiple times.
7. Drain the baths and build pressure to 40kpa.
8. Flushing the apertures.
9. Drain the two baths and add 3.5ml of fluid into the baths respectively, zap the
baths for 4s and build vacuum to -24kp.
10. Wash the back baths, switch on/off valve 7 and 8 for multiple times to strengthen
the cleaning effect of the valves and remove residual probe cleanser.
11. Empty the vacuum, switch on/off valve 18 for multiple times to strengthen the
cleaning effect of the valves and remove residual probe cleanser.
12. Release the pressure, the analyzer restores to "Ready" status.
5.5.4.8 Intensified probe cleanser soak sequence
Soaking procedure:
5-22
Fluidic System
Introduction: the intensified probe cleanser soak procedure is almost the same as the general
probe cleanser soak procedure, the only difference lies in the dilution ratio of probe cleanser.
5-23
Fluidic System
Cleaning procedure:
The cleaning operations of the intensified and general probe cleanser soak procedure
are almost the same, the only difference lies in the occurrence time of the operation.
Introduction:
1. Build vacuum in the vacuum chamber to drain the back bath and rinse
tubes.
2. Drain the RBC bath, the diluent syringe withdraws for 1.3ml to drain the
charging line of RBC bath.
3. The lyse syringe aspirates and discharges lyse to the WBC bath for
multiple times to drain the lyse tube.
5-24
Fluidic System
4. The diluent syringe aspirates and discharges diluent to the WBC bath for
multiple times to drain the diluent tube.
5. The sampling syringe aspirates 80ul of fluid.
6. The sample probe goes inside the WBC bath to drain the sampling tube.
7. Drain the charging line and the waste tube of the probe wipe.
8. Push the 80ul of fluid to the syringe inlet.
9. After build vacuum in the vacuum chamber, open the rinse tubes and empty
tubes of the back baths.
10. Empty the vacuum chamber and build vacuum at the same time, open V5
and V6 of the volumetric tube and dry the volumetric tube.
11. Release vacuum and pressure, the syringes return to home position, the
sample probe returns to the sampling position.
5-25
6 Hardware System
6.1 Introduction
The hardware system consists of 8 boards, which are power board, data board, drive board,
indicator board, touch screen control board, volumetric boars, sample compartment connector
board, and USB interface board; the system also includes the drive and detect components
that require power supply (such as motors, valves, pumps, sensors, display, and filter of input
power) and the wires connecting boards and components.
6-1
Hardware System
sending alarms.
5. Peripherals and interfaces: display/touchscreen, recorder, USB interfaces (for printer,
keyboard and barcode scanner), Ethernet interface and LIS serial port. Besides,
peripherals includes status indicator, key-presses and aspirate key input.
6-2
Hardware System
6-3
Hardware System
6-4
Hardware System
(2) After completing step (1), plug the two wires on of the drive board in turn to see if the power
can be started; if yes, the problem of the drive board can be excluded, the data board needs to be
replace; if no, unplug the wire of the volumetric board; if the power can be started, that means the
volumetric board or its wire is short-circuited, the volumetric board or its wire shall be replaced; if
not, that means the drive board is short-circuited, the drive board shall be replaced.
If the power can be started normally, troubleshoot the error per the following sections.
6.2.1 Introduction
The data board consists of the analog and digital parts, the analog part filters, amplifies, outputs
and processes signals to obtain the signals that are suitable for A/D data conversion. The digital
part processes, outputs, controls and transmits data. It is the core part of the data board or even
the entire hardware system.
Section 6.2 is the servicing and troubleshooting guideline of the data board.
6.2.2 Structure
Introduction of Functions
See Figure 6-5 for the structural diagram of the data board.
6-5
Hardware System
6-6
Hardware System
P1 Interface of CF card 50 /
6-7
Hardware System
J7 Interface of recorder 6 /
6-8
Hardware System
J30
J29
J5
J20
J22
J2
J1
J12
J13 J18 P1
Indicator Function
FPGA_LED Indicator of FPGA logical work, it filters when the logical work goes on
normally
6-9
Hardware System
Name or location
No. Description
of test points
1 VCC Digital 5V power
2 VDD Digital 3.3V power
3 D_1V8 Digital 1.8V power
4 D_1V5 Digital 1.5V power
5 D_2V5 Digital 2.5V power
6 D_1V25VRF Digital 1.25V power
7 D_1V25VTT Digital 1.25V power
6-10
Hardware System
6-11
Hardware System
No. Function
6.2.4 Troubleshooting
Table 6-5 lists the common errors and troubleshooting methods of the data board from the
hardware point of view, the errors caused by software are not included. But many hardware errors
must be inspected by the software.
You need to check the following items before troubleshooting the errors:
1. Check if the wires are firmly connected to the data board;
2. Check if the wires are connected to the sockets of the same No., and if the wires are
cracked or damaged.
3. Check if the input power of socket L18 is normal (test +5V and +12V with a multimeter).
4. Check if the indicator of the data board is in normal condition according to Table 6-5.
After confirming all the above items are in normal condition, do as instructed in Table 6-5 to
troubleshoot the errors.
1 LCD blanks 1: Press the reset button S12 on the data board, if the Press S12
6-12
Hardware System
Replug the
connection
2: Check if the data board if firmly connected to the
wires of the
inverter and LCD display. Replug the connection wires,
data board and
if the error is cleared, it can be concluded as an
the inverter
insecure connection error; if not, do step 3.
and LCD
display.
Replace the
connection
3: Replace the connection wires of the data board and
wires of the
the inverter and LCD display, if the error is cleared, it
data board and
can be concluded as a connection wire failure; if not, do
the inverter
step 4.
and LCD
display.
6-13
Hardware System
14: Replace LCD display and the inverter (display Replace the
assembly), if the error is cleared, then the display display
assembly failure can be concluded. assembly
Replug the
connection
1: Replug the connection wires of the data board and
wires of the
the inverter and LCD display, if the error is cleared, it
data board and
can be concluded as an insecure connection failure; if
the inverter
not, do step 2.
and LCD
display.
Replace the
connection
2: Replace the connection wires of the data board and
wires of the
LCD display the inverter and LCD display, if the error is cleared, it
2 data board and
flickers can be concluded as a connection wire failure; if not, do
the inverter
step 3.
and LCD
display.
6-14
Hardware System
Replug the
1: Check if the data board if firmly connected to the LCD
connection
display. Replug the connection wires, if the error is
wire of the data
cleared, it can be concluded as an insecure connection
board and LCD
error; if not, do step 2.
display
Replace the
2: Replace the connection wires of the data board and connection
the LCD display, if the error is cleared, it can be wire of the data
concluded as a connection wire failure; if not, do step 3. board and LCD
display
Spotted LCD
3
display
3: Check if there is solder joint on U6 weld, if yes, cut off
Cut off the
the solder joint when power is off. Reconnect the power,
solder joint
see if the error is cleared, if yes, the solder joint failure
with a knife.
can be concluded; if not, do step 4.
4: Replace the data board, if the error is cleared, the Replace the
data board failure can be concluded; if not, do step 5. data board
Replug or
2: D47 and D48 is on, poor connection of the network
replace the
wire, or the wire is damaged.
network wire
6-15
Hardware System
4: When power is connected, D70, D71, D72 and D73 Replug the
are all on, replug the wire connected to the USB port. If wire connected
the error is cleared, it can be concluded as an insecure to the USB
connection error; if not, do step 5. port
12V analog 1 Condition: the power wire is firmly connected. Replace the
voltage data board
2 If D20 is off, that indicates the data board failure; if
7 abnormal
not, do step 3.
6-16
Hardware System
Analog -5V 2 If D21 is off, that indicates the data board failure; if
Replace the
11 voltage not, do step 3.
data board
abnormal
3 Test voltage of the test point -5V with the multimeter, if
the result is outside [-4.75-5.25]V, then data board
failure can be concluded.
1. Condition: check if the power wire and the wire of Replace the
HGB sensor are firmly connected, and if +/-12V and HGB lamp
HGB blank +/-5V are under normal status. The error cannot be
10 voltage cleared by software operation and cleaning,
abnormal
2. See if the HGB lamp is off, if so, then the HGB lamp
failure can be concluded; if not, proceed with the
6-17
Hardware System
next step.
6.3.1 Introduction
The drive board responds to the commands sent by the data board, controls the mechanical (e.g.
motor transmission assembly) and fluid components (e.g. valves and pumps) of the analyzer and
reports information like temperature and voltage to the data board. When controlling the
mechanical components, the drive board detects the position of the components (by
photocouplers, etc.), and when controlling the fluid components, it also monitors their pressure.
6.3.2 Structure
The drive board consists of the power supply, central control module, detection module and power
drive module.
6-18
Hardware System
6-19
Hardware System
2 Click "Start", the dialog box "Remove the Rinse tube from the container and press [OK] to
continue." will pop up, do accordingly and then click "OK".
3 A progress bar will be displayed; after the progress ends, a dialog box will pop up.
1) Adjust rinse photocoupler calibration potentiometer VR1 (see Figure 6-11) manually until
the rinse sensor calibration indicator D22 (see Figure 6-10) turns on.
2) Put the rinse tube back to the container (make sure there is rinse in the rinse container),
click "OK" to close the dialog box.
6-20
Hardware System
6.3.6 Troubleshooting
1) Checks before troubleshooting
Before troubleshooting the drive board, you should first check if the wires are firmly connected, if
they are connected to the sockets of the same No., and if the wires are damaged.
When you suspect that drive board failure occurs, check if the indicators are under normal status
per the following table.
6-21
Hardware System
If all the indicators are confirmed to be ok, check if the MCU and FPGA versions are correct
on the software screen (Click the menu option"Service" "Version Info."); if yes, troubleshoot
the error as instructed in the following section.
2) Troubleshooting
You can roughly locate the error by the alarm, then accurately locate the error by its type and
dispose it, see Table 6-7.
Table 6-7 Troubleshooting methods
6-22
Hardware System
6-23
Hardware System
6-24
Hardware System
photocoupler assembly.
a The aspirate 1 Check if the wires of the aspirate key and the
key does not sample compartment connection board are loose
respond when or damaged, if yes, replug or replace the wires.
being pressed.
7 Micro-switch 2 if the error cannot be cleared, disassemble the
b The sample switch of the aspirate key and the sample
compartment compartment connection board to see if they are
door cannot be covered by fluid spills. If yes, clean and then
closed. reinstall them.
6.4.1 Introduction
In the BC-3600 Auto Hematology Analyzer, the power board provides 6 groups of stable power
output, including D5V, A+12V, A-12V, AC120V, P12V, P24V.
Section 6.4 is the servicing and troubleshooting guideline of the power board.
6.4.2 Structure
Function
The functional diagram of the power system is as follows:
6-25
Hardware System
6-26
Hardware System
Definition
L, live wire end of the power
N, neutral wire end of the power
PIN Definition
6-27
Hardware System
Socket
Name Socket Model
No.
6-28
Hardware System
When disassembling and installing the boards, cut off the power and pull out
the power wire.
Installing:
Do the above steps in reverse order
Verification: 1 Check if the ground wire of AC input socket on the casing is securely connected to
the conductive part of the analyzer chassis.
7 Connect the power wire and switch on the AC switch, the analyzer enters initializing status
and the indicators on the board turn on.
Make sure the power supply assembly and the analyzer chassis are fastened
by screws.
The disassembling operation must be done after the power board and the
surrounded parts cool down.
6.4.5 Troubleshooting
The errors of the power board can be troubleshooted per the following procedure.
6-29
Hardware System
6.5.1 Introduction
The USB interface board is extended to the front cover of the analyzer by extension wire to
provide users with a USB interface. The USB interface board does not need to be adjusted.
6-30
Hardware System
6.5.2 Troubleshooting
When the USB interface on the front cover cannot be used, do as follows:
1Check if the data board is working properly, if not, handle the problem of the data board first.
2Check if the wire connecting the USB interface board and the data board is loose or damaged,
if yes, replug or replace the wire; if not, check if the USB interface board is cover by fluid spills,
replace the board if so.
3If the problems mentioned in the above step are excluded, replace the data board.
6.6.1 Introduction
Touchscreen control board is the interface of the touchscreen to the data board, it converts the
touch operations of users to signals recognizable to the data board. The touchscreen control
board does not need to be adjusted.
6-31
Hardware System
6.6.2 Troubleshooting
When pressing The wire connecting Check if there is any crack on the
1
the touchscreen, the touchscreen touchscreen, if yes, replace the
the cursor can control board and touchscreen.
2 only move the touchscreen is
Replug the wire
2
horizontally or loose/the
touchscreen is
vertically cracked
6.7.1 Introduction
The volumetric board detects the pressure of the pressure and vacuum chambers and measures
fluid volume. The board has been calibrated in factory, so you do not need to calibrate it before
using it.
6-32
Hardware System
6.7.2 Troubleshooting
Click "Service"
1 "System Test", and then click
the "WBC Test Time" and "RBC Test Time" buttons
on the screen to see if the error can be cleared.
Including but
not limited to the If the error cannot be cleared, check if the data
2
following errors: board is working properly; if not, resolve the problem
Abnormal of data board first.
WBC clog
1
1 detection
If data board error is excluded, check if the wires
3
of fluid WBC bubbles
2
connecting the volumetric board, the drive board and
RBC clog
3 the data board are loose or damaged; if the wires are
loose, replug them; if they are damaged, replace
RBC bubbles
4
them.
6-33
Hardware System
first.
Click
1 "Service"
"System Test", and then click
the Vacuum Of VC, Pressure Of VC and Pressure Of
PC buttons on the screen to see if the error can be
cleared.
6.8.1 Introduction
The sample compartment connection board is in the closed tube sampling assembly of closed
tube analyzers, it detects the open/close status of the compartment door and the type of tube
holder adapters. The sample compartment connection board does not need to be adjusted.
6-34
Hardware System
6.8.2 Troubleshooting
The phenomenon of sample compartment connection board error is the analyzer does not
respond to closing operation. Clear the error per the following procedure:
1 Check if the drive board is working properly, if not, handle the problem of the drive board first.
2 Check if the wire of the sample compartment connection board (including J8 of drive board, J1
and the transfer socket of sample compartment connection board) is loose or damaged, if so,
replug or replace the wire.
3 If the problem mentioned in step 1 can be excluded, disassemble the board, check if there are
fluid spills in the switch; if yes, replace the board.
4 If not, replace the drive board.
6.9.1 Introduction
The indicator board tells users the status of analyzer through sound and light.
6-35
Hardware System
6.9.2 Structure
The indicator board consists of indicators of three colors- red, yellow and green, their control
circuits and the drive circuit of buzzer. The indicator board does not need to be adjusted.
6.9.3 Troubleshooting
6-36
7 Servicing
7.1 General
You can service the BC-3600 and BC-3300 as per Section 7.2 7.21. For the repairing with
verification, you must follow the procedures strictly to verify the maintenance.
7-1
Servicing
Make sure the door of sample compartment is closed when opening the
Front Panel, or it may cause damage on the sample compartment and the
Front Panel.
Installation: Install the Front Panel according to the steps stated above in reverse order.
Verification:
Pull the Front Panel to check whether its locked tightly;
Power on the analyzer and verify your replacement.
7-2
Servicing
Figure 7-2 Inside of the left door Figure 7-3 Outside of the left door
Installation: Install the Left Door according to the steps stated above in reverse order.
Verification: Pull the Left Door to check whether its locked tightly.
7-3
Servicing
Installation: Install the Right Door according to the steps stated above in reverse order.
Verification: Pull the Right Door to check whether its locked tightly.
7-4
Servicing
Installation: Install the Top Cover according to the steps stated above in reverse order.
Verification: Check Whether the Top Cover is installed properly.
7-5
Servicing
7-6
Servicing
Installation: Install the Data board according to the steps stated above in reverse order
Verification:
1. Check whether the cables are connected correctly;
2. Power on the analyzer and verify the power and working indicators on the data board;
3. Execute Background test. If there is any error message, please do the
troubleshooting accordingly.
7-7
Servicing
Installation: Install the Power Driver board according to the steps stated above in reverse order
Verification:
1. Check whether the cables are connected correctly;
2. Power on the analyzer and verify the power and working indicators on the Power
Driver board;
3. Execute Background test. If there is any error message, please do the
troubleshooting accordingly.
7-8
Servicing
Installation: Install the touch screen control board according to the steps stated above in
reverse order
Verification:
1. Check whether the cables are connected correctly;
2. Power on the analyzer and verify the replacement.
7-9
Servicing
Installation: Install the Inverter according to the steps stated above in reverse order
Verification:
1. Check whether the cables are connected correctly;
2. Check whether the screws are fastened tightly;
3. Power on the analyzer and verify your replacement.
7-10
Servicing
Installation: Install the USB Interface board according to the steps stated above in reverse
order
Verification:
1. Check whether the cable is connected correctly;
2. Connect the mouse with the USB interface to check whether the cursor on the
display is moving normally. If not, please do the troubleshooting needed.
7-11
Servicing
Installation: Install the Volumetric board according to the steps stated above in reverse order
Verification:
1. Check whether the cable connection between the Volumetric board and power
7-12
Servicing
driver board is correct. Check Whether the Pressure and Vacuum sensor are
connected correctly;
2. Turn on the analyzer. Check whether the background is within range, if not,
please do the troubleshooting needed.
7-13
Servicing
Make sure the sample probe is always located on the upper position during
7-14
Servicing
the disassembly.
Installation: Install the Sample compartment connection board according to the steps stated
above in reverse order
Verification:
1. Check whether the cables are connected correctly between the Sample
compartment connection board and the Power driver board;
2. Turn on the analyzer and check whether the sample compartment is working
normally.
7-15
Servicing
Installation: Install the indicator board according to the steps stated above in reverse order.
Verification:
1. Check whether the cable connection between the Indicator board and the Data
board is correct;
2. Turn on the analyzer. Check whether the indicator can show red, yellow and green
colors correctly when error message displayed, and if the buzzer is working
normally.
Purpose: Follow the procedures to replace the Power Supply Assembly as needed.
Tools: 107 cross-headed screwdriver
Removal:
1. Power off the analyzer and unplug the power cord from the wall outlet;
2. Unplug USB cable, network cable and serial cable connectors on the power
fixing board;
3. Open the left side door as per 7.2.2; Remove the Top Cover as per 7.2.4;
4. Use 107 cross-headed screwdriver to unscrew the grounding screw of Power
supply assembly, unplug all the cable connection. Insert all the cables into the
analyzer;
5. Use 107 cross-headed screwdriver to unscrew the 4 cross-headed sunk screws
on the power fixing board;
6. Take out the Power Supply Assembly.
7-16
Servicing
Installation:
Verification:
1. Check whether the power connections meet the requirement;
2. Check whether the indicators on the data board and power driver board are on
good condition;
3. Check whether the monitoring voltages are within range in Self-test screen.
7-17
Servicing
Installation: Install the Display assembly according the steps stated above in reverse order.
Verification:
1. Check whether all components are installed and fixed in place; Check whether
the cables are connected correctly;
2. Start up the analyzer and check the displaying of the screen.
Installation: Install the Touch Screen according the step1-3 stated above in reverse order.
Verification:
1. Check whether all components are installed and fixed in place; Check whether
7-18
Servicing
7-19
Servicing
Installation: Install the Recorder according the steps stated above in reverse order.
Verification: Start up the analyzer and check the printing of the recorder.
7-20
Servicing
Please empty the liquid system before replacing the valve, otherwise the
reagents might leak out of instrument and cause the biological
contamination.
7-21
Servicing
assembly.
4. Open the top panel(as per section 7.2.4);
5. Unplug the all the tubes connected with the waste pump, please dont disassemble
the fluid pump protecting plate;
6. Disconnect the cable connector between the fluidic diaphragm and electric
diaphragm
7. As following Figure shows, Use the 107 cross-headed screwdriver to remove the
four M3 sunk screws and four spacers.
8. Take out the waste pump assembly.
Please empty the liquid system before replacing the pump assembly,
otherwise the reagents might leak out of instrument and cause the biological
contamination.
7-22
Servicing
7-23
Servicing
7-24
Servicing
Installation: The installation procedures are the reverse order of step 1~5, during the
installation, the direction of the pump and chamber assembly and connection should be
in accordance with previous one.
Verification:
7-25
Servicing
7-26
Servicing
Installation: The installation procedures are the reverse order of step 1~5.
Verification:
1. Check if the parts are assembled properly or not;
2. Make sure the tube connection and power cable connection are correct;
3. Turn on the instrument, go to counting screen, unplug the rinse cap assembly,
dont let the rinse go into the instrument. Count, observe if instrument could
7-27
Servicing
give the alarm. If it could reflect the real situation, that means the sensor
works well.
All the samples, controls, calibrators, reagents, wastes and areas contacted
them are potentially biohazardous. Wear proper personal protective
equipment (e.g. gloves, lab coat, etc.) and follow safe laboratory procedures
when handling them and the contacted areas in the laboratory.
7-28
Servicing
7-29
Servicing
Please adjust the sample probe position, before disassemble the shielding
box, make sure the sample probe is out of the shielding box to prevent the
probe is bended or hurt the operator.
7-30
Servicing
7-31
Servicing
Removal:
1. Empty the liquid system;
2. Power off the instrument and unplug the power cable.
3. Open the front panel assembly(as per section 7.2.1);
4. Open the right side panel(as per section 7.2.3)
5. Open the top panel(as per section 7.2.4);
6. Disassemble the shielding box(as per section 7.9.1);
7. Unplug the tubes and cable connectors on the counting bath;
8. As following Figure shows. Use the 107 cross-headed screwdriver to remove
the two M36 pan head screws fixing the counting bath, and remove the
counting bath cover board;
9. Take out the WBC counting bath.
7-32
Servicing
Removal:
1. Disassemble the WBC assembly(as per section 7.9.3);
2. Use the cross-headed screwdriver to remove the two M2X10 screws,
disassemble the HGB assembly from counting bath.
7-33
Servicing
the two M36 pan head screws fixing the counting bath, and remove the
counting bath cover board;
9. Use cross-headed screwdriver to remove the ground cable, take out the WBC
counting bath.
7-34
Servicing
Purpose: This part is used to dispense the fixed volume reagent or sample. In case of
malfunction, please replace the assembly in time, following is the detail steps.
Tool: 107 cross-headed screwdriver (107X75)
Removal:
1. Empty the liquid system;
2. Power off the instrument and unplug the power cable.
3. Open the top panel(as per section 7.2.4);
4. Open the right side panel (as per section 7.2.3), disassemble the lyse bottle and
cap assembly.
5. Unplug all the tubes on the syringe;
6. Unplug the ground cable of filter, and unplug the syringe motor cable
connector inside of instrument;
7. As following Figure shows. Use the 107 cross-headed screwdriver to remove
7-35
Servicing
the M3 pan head screws, remove the gasket, then take out the 10ml syringe
assembly or dual-syringe assembly.
Please empty the liquid system, before replacing the syringe assembly.
Otherwise, itll cause reagent leak or biological contamination. The syringe
assembly is a little heavy, during replacement, please support the syringe
assembly by hand, to prevent it drops and hurt people or instrument.
7-36
Servicing
During installation, please care about the probe, to prevent the pricks. After
installation, please recalibrate the horizontal and vertical position.
7-37
Servicing
Figure 7-36 The screen to adjust the sample probe and wipe block
2. Adjust the wipe block:
For closed-reagent system: First, open the front panel(At this time, itll show
front panel is open error message in screen, to take care of it after
adjustment), see Figure-6B, Disassemble the tube baffle, remove the wipe
block, and assemble the positioning calibration fixture of sample probe on the
wipe block supporter by probe wipe fixing pin; Press wipe block position in
Y-direction motor as Figure 7-36 shows, then press start button, after
initialization, press up or down button to adjust the positioning calibration
fixture of sample probe, make its bottom is in the same level with sample
needle-point, see Figure-6C ; Then press save to save the setting; Remove
the fixture, and assemble the wipe block and probe wipe fixing pin, tighten
tube baffle to finish adjustment.
For the open-reagent system: open the front panel, remove the wipe block, and
assemble the positioning calibration fixture of sample probe on the wipe block
supporter by probe wipe fixing pin, the adjustment steps are same with above,
then remove the fixture, and assemble the wipe block to finish the adjustment.
7-38
Servicing
Tube baffle
Figure 7-38 Sample probe is in the same level with the wipe block
3. Adjust WBC bath injection position: First, disassemble the shielding box, then
remove counting bath diaphragm as Figure 7-39 shows, Press WBC bath in
X-direction motor as Figure-6A shows. Then press start, press right to
move the sample probe to the right side, then place the WBC/RBC bath
calibration fixture properly and stably on the WBC bath as Figure 7-40 shows,
Press lift button in the software screen to move the probe just into the
aperture of fixture, then press save.
7-39
Servicing
Counting bath
diaphragm
4. Adjust the RBC bath injection position: The same with above procedures,
Press RBC bath in X-direction motor to adjust the RBC bath injection
position and save the setting as Figure-6F shows.
7-40
Servicing
All the samples, controls, calibrators, reagents, wastes and areas contacted
them are potentially biohazardous. Wear proper personal protective
equipment (e.g. gloves, lab coat, etc.) and follow safe laboratory procedures
when handling them and the contacted areas in the laboratory.
7-41
Servicing
socket screws, then take out the vertical movement assembly in front.
7-42
Servicing
Installation: The installation procedures are the reverse order of disassembly, before
tightening the two Allen type stock screws on slide block, move the horizontal part to
right side, and keep it is closed with the end face of slide block, then tighten the crews.
After installation, please recalibrate the position of sample probe.
Verification:
1. Check if the parts are assembled properly or not;
2. Turn on the instrument to verify.
During adjustment, please wait for the Menu to become the normal ground
color before operation, otherwise, the system is busy, please try again
later warning message will pop-up;
Please make sure the tube baffle is installed properly, otherwise there is a
risk to happen interference;
After counting bath diaphragm installation, please make sure the counting
bath diaphragm is not crimped.
7-43
Servicing
7-44
Servicing
All the samples, controls, calibrators, reagents, wastes and areas contacted
them are potentially biohazardous. Wear proper personal protective
equipment (e.g. gloves, lab coat, etc.) and follow safe laboratory procedures
when handling them and the contacted areas in the laboratory.
7-45
Servicing
3. Pull the probe wipe fixing pin downward by hand as following Figure shows;
7-46
Servicing
All the samples, controls, calibrators, reagents, wastes and areas contacted
them are potentially biohazardous. Wear proper personal protective
equipment (e.g. gloves, lab coat, etc.) and follow safe laboratory procedures
when handling them and the contacted areas in the laboratory.
7-47
Servicing
During disassembly and installation, please keep the sample probe always in
upper position.
Installation:
7-48
Servicing
7-49
Servicing
1. When disassembling the sample compartment door separately, install the door on the
assembly, then slightly screw the four M3x8 screws to fix the door, not too tight;
2. Close the front panel, move the door, make the upper gap and side gap almost same;
3. Open the front panel, make sure the compartment door not to be implicated;(please
hold the door by your hand)
4. Tighten the four M3x8 screws to finish the installation and adjustment;
5. When replacing the whole sample compartment assembly, loose the two M3x16
stock head screws fixing the door supporter;
6. Repeat the step 1 to step3;
7. Tighten the two M3x16 stock head screws and four M3x8 screws to finish the
installation and adjustment.
7-50
Servicing
Installation: Insert the fixture of tube holder adapter to corresponding card slot, and
tighten the M4x12 socket head screws.
Verification: Make sure all the parts are assembled properly.
7-51
Servicing
Installation: Locate the tube baffle as the position of screws, tighten the two screws.
Verification: Make sure all the parts are assembled properly.
7-52
Servicing
7-53
Servicing
7-54
Servicing
Figure 7-55 Disassemble the flanged deep-slot ball bearing in left side
1 flanged deep-slot ball bearing 2 pan head screw M3X8
5x14x3.5
2. Disassemble the flanged deep-slot ball bearing in left side(with motor). Use
the cross-headed screwdriver to loose the four M38 pan head screws to
remove the synchronous belt;
3. Use the 2.5mm hex wrench to loose the two M3x12 screws to remove the
big band wheel;
4. Use cross-head driver to loose the two M3x8 small pan head screws,
remove the right side flanged deep-slot ball bearing.
7-55
Servicing
Figure 7-56 Disassemble the right side flanged deep-slot ball bearing
1synchronous belt 2big band wheel
3 M3X12 Allen type stock screw 4 Pan head screw M3X8
5 flanged deep-slot ball bearing
5x14x3.5
Installation:
1. The installation procedures are the reverse order of disassembly;
2. The outside of the big band wheel should be parallel with the shaft surface;
3. Tighten the screws;
4. The tension of synchronous belt. Dont tighten the four screws fixing the motor at the
first, push the motor to force the synchronous belt tight(about 1kg force), then use the
cross-head driver to tighten the four screws.
Verification: The same with Section 7.11.1.
Purpose: The start key can be replaced or adjusted as instructed in this section.
Tools: 2.5mm hex wrench;
Removal:
1. Power off the instrument and unplug the power cable.
2. Open the front panel assembly(as per section 7.2.1);
3. Open the right side panel(as per section 7.2.3), Disassemble the lyse bottle and
cap assembly.
7-56
Servicing
4. As following Figure shows, Use the 2.5mm hex wrench to remove two M36
Allen type socket screws, take out the start key;
7-57
Servicing
7-58
Servicing
Purpose: Detection assembly is used to detect if the front panel is open or not, when its
defective, need to replace.
Tools: 107x75 cross screw driver
Removal1. Power-off the main unit and plug out power cord.
2. Open the front panel, the steps and notice as 7.2.1 indicates.
3. Open the top panel, the steps and notice as 7.2.4 indicates.
4.As figure 7-60, loose the three M3x6 cross countersunk head screws,and
take down the open-close detection assembly.
7-59
Servicing
7-60
Servicing
7-61
Servicing
All the samples, controls, calibrators, reagents, wastes and areas contacted
them are potentially biohazardous. Wear proper personal protective
equipment (e.g. gloves, lab coat, etc.) and follow safe laboratory procedures
when handling them and the contacted areas in the laboratory.
The reagents are irritating to eyes, skin and diaphragm. Wear proper
personal protective equipment (e.g. gloves, lab coat, etc.) and follow safe
laboratory procedures when handling them in the laboratory.
If the reagents accidentally spill on your skin, wash them off with plenty of
water and if necessary, go see a doctor; if the reagents accidentally spill into
your eyes, wash them off with plenty of water and immediately go see a
doctor.
When loose the Cap connecter, and be careful with left liquid drops on the
instrument or table.
Please tighten the reagent cap in case of the reagent contaminated when the
reagent and analyzer was connected.
7-62
Servicing
2Only the edit is activated, you can adjust the gain value. If the gain setup
exceeding the effective range or the value is empty, the system will
give Input invalid, and recover the values back to original.
3After input the valves, you can press the menu or other figure button, it
will pop up following dialogue. Press Yes, Save the setting and switch
the screen; click No to exit the dialogue without save.
7-63
Servicing
Figure 7-64 WBC counting bath and HGB assembly (Right panel)
7-64
Servicing
7-65
Servicing
7-66
Servicing
7-67
Servicing
there is no leakage
3 Perform gain calibration
4 Verify the HGB and MCV values, as well as the peak
values in the WBC histogram after gain calibration
5 Monitor the background information
6 Calibrate in the whole-blood mode
7 Run the calibrator after finishing calibration, and
verify the result according to the specifications in the
PRS
Calibrate in the predilute mode
8
Run the calibrator after finishing calibration, and
9
verify the result according to the specifications in the
PRS
1 Empty fluidics and shut down the analyzer
2 Replace the syringe and start up the analyzer
according to standard procedures
3 Make sure the tubes are connected properly and
there is no leakage
4 Calibrate in the whole-blood mode
5 Run the calibrator after finishing calibration, and
verify the result according to the specifications in the
2.5ml home-made syringe
12 PRS
(fluorine rubber)
Calibrate in the predilute mode
6
7 Run the calibrator after finishing calibration, and
verify the result according to the specifications in the
PRS
8 Test repeatability using the normal-level control in the
whole-blood mode
9 Test repeatability using the normal-level control in the
predilute mode
1 Empty fluidics and shut down the analyzer. Replace
the syringe, and then start up the analyzer according
to standard procedures
2 Make sure the tubes are connected properly and
there is no leakage
3 Remove bubbles in the 100ul syringe
100L syringe service 4 Calibrate in the whole-blood mode
13
assembly 5 Run the calibrator after finishing calibration, and
verify the result according to the specifications in the
PRS
Calibrate in the predilute mode
6
7 Run the calibrator after finishing calibration, and
verify the result according to the specifications in the
PRS
7-68
Servicing
7-69
Servicing
7-70
Servicing
7-71
Servicing
1 Export parameters
2 Replace the data board and start up the analyzer
34 Driver board
according to standard procedures
3 Restore parameters
1 Connect to the power supply, and make sure that you
can start up and shut down the analyzer by pressing
35 Power board the power button
2 In the system status screen, make sure all the
voltage values are in specified ranges
1 Make sure that the interval between the shielding
cover of the interface board and the side door of the
circuit is even
36 Interface board 2 Test all the USB interface with the USB interface of
the keyboard to make sure all the interfaces function
properly
3 Test the serial interfaces
1 Empty fluidics and shut down the analyzer. Replace
the volumetric board, and then start up the analyzer
according to standard procedures
2 Check and make sure the pressures of the vacuum
chamber and pressure chamber are OK
3 Monitor the background information
4 Calibrate in the whole-blood mode
5 Run the calibrator after finishing calibration, and
verify the result according to the specifications in the
37 Volumetric metering board
PRS
Calibrate in the predilute mode
6
7 Run the calibrator after finishing calibration, and
verify the result according to the specifications in the
PRS
8 Test repeatability using the normal-level control in the
whole-blood mode
9 Test repeatability using the normal-level control in the
predilute mode
1 Open the front cover, check if the indicator is red and
38 Indicator Board
the buzzer buzzes
Sample compartment 1 Go to the system test screen and perform the sample
39
connection board compartment test. Make sure the test result is OK
TR60-D recorder driver 1 Print at the count screen and make sure the printout
40
board is OK
41 Touch Screen 1 Calibration on Touch Screen after replacement
1 Make sure the analyzer can be started up and the
42 Inverter
screen displays properly
43 Photocoupler and its 1 Run a background cycle and make sure the sampling
7-72
Servicing
7-73
Servicing
PRS
7 Test repeatability using the normal-level control in the
whole-blood mode
8 Test repeatability using the normal-level control in the
predilute mode
1 Fix the position of the sample probe wipe
2 Adjust the position of the sample probe in the
WBC/RBC bath and the sample compartment
3 Calibrate in the whole-blood mode
4 Run the calibrator after finishing calibration, and
verify the result according to the specifications in the
PRS
50 Vertical motion assembly Calibrate in the predilute mode
5
6 Run the calibrator after finishing calibration, and
verify the result according to the specifications in the
PRS
7 Test repeatability using the normal-level control in the
whole-blood mode
8 Test repeatability using the normal-level control in the
predilute mode
1 Empty fluidics and shut down the analyzer
Fluidic Pipe Bracket 2 Replace the assembly and start up the analyzer
51
Assembly according to standard procedures. Make sure there is
no leakage
1 Empty fluidics first. Replace the syringe, and then
start up the analyzer according to standard
procedures
2 Make sure the tubes are connected properly and
there is no leakage
3 Remove bubbles in the 100ul syringe
4 Calibrate in the whole-blood mode
5 Run the calibrator after finishing calibration, and
verify the result according to the specifications in the
52 Double Syringe Assembly
PRS
Calibrate in the predilute mode
6
7 Run the calibrator after finishing calibration, and
verify the result according to the specifications in the
PRS
8 Test repeatability using the normal-level control in the
whole-blood mode
9 Test repeatability using the normal-level control in the
predilute mode
Double Syringe Drive 1 Empty fluidics first. Replace the syringe, and then
53
Assembly start up the analyzer according to standard
7-74
Servicing
procedures
2 Make sure the tubes are connected properly and
there is no leakage
3 Remove bubbles in the 100ul syringe
4 Calibrate in the whole-blood mode
5 Run the calibrator after finishing calibration, and
verify the result according to the specifications in the
PRS
Calibrate in the predilute mode
6
7 Run the calibrator after finishing calibration, and
verify the result according to the specifications in the
PRS
8 Test repeatability using the normal-level control in the
whole-blood mode
9 Test repeatability using the normal-level control in the
predilute mode
1 Empty fluidics first. Replace the syringe, and then
start up the analyzer according to standard
procedures
2 Make sure the tubes are connected properly and
there is no leakage
3 Calibrate in the whole-blood mode
4 Run the calibrator after finishing calibration, and
verify the result according to the specifications in the
54 10ml Syringe Assembly PRS
Calibrate in the predilute mode
5
6 Run the calibrator after finishing calibration, and
verify the result according to the specifications in the
PRS
7 Test repeatability using the normal-level control in the
whole-blood mode
8 Test repeatability using the normal-level control in the
predilute mode
1 Empty fluidics first. Replace the syringe, and then
start up the analyzer according to standard
procedures
2 Make sure the tubes are connected properly and
there is no leakage
Single Syringe Drive
55 3 Calibrate in the whole-blood mode
Assembly
4 Run the calibrator after finishing calibration, and
verify the result according to the specifications in the
PRS
Calibrate in the predilute mode
5
6 Run the calibrator after finishing calibration, and
7-75
Servicing
7-76
8 Maintaining your analyzer
8.1 General Guidelines
Maintenance Period Content of Maintenance
8-1
Maintaining your analyzer
8.2.2 Calibration
Calibration is a procedure to standardize the analyzer by determining its deviation under
certain specified conditions. In order to get accurate sample analysis results, you should
calibrate the analyzer per the procedure below when necessary. See Chapter Using the
calibration programs in operation manual.
Notes
1. Only use the controls and calibrations within expiry date. After being taken out of the
refrigerator, the controls and calibrations should be placed in environment with room
temperature for 15mins before mixed or used.
2. Mark the open-box date on the package bottle of those new lots of controls and calibrations.
Mixing skills
After placing the controls and calibrations for 15mins, mix them as followings. Mixing time for
each tube should be NOT less than 5mins with enough time for each step.
1. Tube heads upward. Rub the tube with two hands in low speed, for 1.5~2mins.
8-2
Maintaining your analyzer
2. Tube heads downward. Rub the tube with two hands in low speed, for 1.5~2mins.
Figure 8-4 Comparison of well mixed sample and poorly mixed sample
5. Cap the tube well after each test of controls or calibrations to ensure their stability.
6. After mixing well, you need only to shake the controls or calibrations slightly before each
test.
7. After a group tests or being placed for more than 5mins, controls or calibrations should be
mixed as well as STEP 4 before they are use again.
8-3
Maintaining your analyzer
NOTES
1. Put the controls and calibrations back to the refrigerator for more than 1 hour after using.
2. NOT place the controls and calibrations uncapped during the whole process, in case that
the evaporation impacts the result.
3. During the breaks of a group of tests, you need only to shake the controls or calibrations
slightly, in case that severe shaking impacts the result.
4. After opened, the period of validity is 14 days for controls is and 7 days for calibrations in
refrigeration environment. Controls and calibrations out of period of validity are prohibited to
use again.
8-4
9 Error Information
9-1
Error Information
If Remove Error does not work in the following error mode, check and deal with the errors as
instructed in the following table.
9-2
Error Information
9-3
Error Information
Building
pressure is
Instruction collision
not allowed
when building pressure Change driver board or data board.
in the
in the pressure chamber
pressure
chamber.
9-4
Error Information
Expiration date
Change for new reagent or change the
Diluent expired is out of the set
expiration date.
range.
Expiration date
Change for new reagent or change the
Rinse expired is out of the set
expiration date.
range.
Expiration date
Change for new reagent or change the
Lyse expired is out of the set
expiration date.
range.
Expiration date
Change for new reagent or change the
Reagent kit expired is out of the set
expiration date.
range.
9-5
Error Information
Sampling
assembly X
X motor actual action
motor Change driver board or data board.
overtime
movement
overtime
Sampling
When the sampling assembly 1. Check whether the photocoupler is normal.
assembly
is working, the X motor is not 2. Check if the motor and drive assembly miss
action
in the allowed position. the steps or are resisted.
forbidden
Sampling
assembly Y
Y motor actual movement
motor Change driver board or data board.
overtime
movement
overtime
Sampling
When the sampling assembly 1. Check whether the photocoupler is normal.
assembly
is working, the Y motor is not 2. Check if the motor and drive assembly miss
action
in the allowed position. steps or are resisted.
forbidden
Sampling When Y motor is piercing, the
1. Check whether the photocoupler is normal.
assembly Y baffle fails to pass the piercing
2. Check the piercing action of the sample
motor piercing center of the photocoupler
probe.
error area.
ASP motor photocoupler
error, or the motor fails to run
ASP/LS syringe 1. Check whether the photocoupler is normal.
to the photocoupler position
fails to find the 2. Check if the motor and drive assembly miss
for missing steps or the motor
home position. steps or are resisted.
cannot drive the sample
probe to pierce the cap.
ASP/LS motor Control instruction collision of
Change driver board or data board.
is working. the ASP motor
After the movement: The
moving steps of the ASP
1. Check whether the photocoupler is normal.
ASP/LS motor motor displayed that it shall
2. Check if the motor and drive assembly miss
action failure 1 be in the photocoupler area,
steps or are resisted.
and the photocoupler is not
blocked.
After the movement: The
moving steps of the ASP
1. Check whether the photocoupler is normal.
ASP/LS motor motor displayed that it shall
2. Check if the motor and drive assembly miss
action failure 2 not be in the photocoupler
steps or are resisted.
area, but the photocoupler is
blocked.
Action 1 is not Before the movement: The 1. Check whether the photocoupler is normal.
allowed by moving steps of the ASP 2. Check if the motor and drive assembly miss
9-6
Error Information
9-7
Error Information
9-8
Error Information
9-9
Error Information
9-10
Error Information
tube) short.
9-11
Error Information
Note: The following figures are got from the R & D debug platform and are only used to assist
the error diagnosis with the help of the histograms.
If the lyse reaction is abnormal in the WBC channel, the shape of the WBC histogram varies as
shown in the following Figure 9-2.
9-12
Error Information
Observe the variation of the WBC histogram. If the peak of the histogram moves slightly to the
right, generally it is because of insufficient reaction, check whether the adding of reagents in
WBC bath is normal, or change for another batch of reagents. If the WBC histogram varies
seriouslyit is possibly caused by insufficient lyse, check the adding of reagents, and also
relevant factors such as the mixing up the WBC bath, liquid level of the front bath, bubbles in
the back bath and so on.
9-13
Error Information
9-14
Error Information
3. Hemolytic anemia
Parameter result Histogram
9-15
Error Information
R3
R2R3Rm
9-16
Error Information
R2R3R4Rm
R2R3Rm
9-17
Error Information
R1R3Rm
Pm
Figure 9-13 Histogram of the chronic myelocytic leukemia sample during the treatment with
interference of NRBC
Pm
Pl
Figure 9-14 Reason for leucopenia - Histogram with interference of RBC debris
9-18
Error Information
11. Thrombocytosis
Parameter result Histogram
R1R2R3Rm
9-19
Error Information
14. Lymphocytosis
Parameter result Histogram
R3
Pm
Figure 9-18Histogram of lymphocytosis sample
9-20
Error Information
15. Monocytosis
Parameter result Histogram
R2R3Rm
The browse function of the present sample pulse of the system helps the analyzer a lot to
diagnose the complicated errors.
9-21
Error Information
9-22
Error Information
When the background is clean, most part of the channels of background count is saturated
pulse formed by the small bubbles as shown in the above figure. Only a small quantity of
particles scatter everywhere in the pulse figure.
9-23
Error Information
In normal condition, the pulse width of WBC, RBC and PLT are generally consistent, but the
pulse peak of WBC is distributed unevenly, while the pulse heights of RBC are distributed
consistently, and the pulse peak of PLT is the lowest. When refer to the pulse spacing the
pulse distribution of WBC are sparse, while the RBC distribution is dense, the PLT is generally
scattered between other pulses.
9-24
Error Information
The above figure shows the interference pulses of each channel when the shielding of the bath
is ineffective. Feature: The shapes of the pulses are irregular, the pulses overlap a lot, and the
pulse width is narrow, while the heights are distributed unevenly.
9-25
Error Information
Figure 9-29 RBC pulse when there is no fluid in the back bath
Figure 9-30 PLT pulse when there is no fluid in the back bath
When there is no fluid at the back bath or when a lot of bubbles are aspirated, the RBC/PLT
signal baseline will disappear; in the meantime, the pulse will be fully saturated.
9-26
10 Appendices
Please provide the code and name of the MINDRAY spare parts listed in this manual when you
order and purchase spare parts from MINDRAY. This will help us offer you the spare parts you
need as soon as possible. Choosing spare parts by MINDRAY will ensure the perfect working
state of you analyzer.
A.1 List of Spare PCBA
No. Description MINDRAY Remark
code/model
1 Power supply board 801-3007-00001-00
2 Data board 801-3007-00002-00
3 Driver board 801-3007-00003-00
4 Touchscreen control board 801-3007-00004-00
5 Indicator board 801-3007-00005-00
6 Recorder driver board 801-3007-00006-00
7 USB interface board 801-3007-00007-00
8 Volumetric board 801-3007-00008-00
9 Sample compartment connecting only applicable to
801-3007-00009-00
board closed tube model
A-1
Appendices
motor
11 Micro-switch 801-3007-00014-00
12 WBC bath assembly 801-3900-00001-00
13 RBC bath assembly 801-3007-00015-00
WBC bath (without aperture)
14
maintenance and repair part 801-3900-00003-00
RBC bath (without aperture)
15
maintenance and repair part 801-3900-00004-00
WBC bath (without HGB unit)
16
maintenance and repair part 801-3900-00005-00
Maintenance and repair part of bath
17
washer 801-3900-00006-00
18 Tube kit under the bath 801-3007-00016-00
19 Aperture sensor (D80um) 801-2800-00013-00
20 RBC aperture (D70um) 801-3110-00078-00
21 HGB bath O-ring 801-3900-00095-00
22 Sampling assembly 801-3007-00017-00
23 Vertical action assembly 801-3007-00018-00
24 Horizontal action assembly 801-3007-00019-00
only applicable to
25
Probe wipe clamp (Open vial) 801-3900-00013-00 open vial model
only applicable to
26
Probe wipe clamp (Closed tube) 801-3900-00014-00 closed tube model
only applicable to
27
Closed-tube sample probe 801-3900-00015-00 open vial model
only applicable to
28
Open-vial sample probe 801-3101-00002-00 closed tube model
29 10ml syringe assembly 801-3900-00054-00
30 Single syringe drive assembly 801-3900-00053-00
31 10ml syringe 801-3900-00009-00
32 Double syringe assembly 801-3900-00051-00
33 Double syringe drive assembly 801-3900-00052-00
34 2.5ml syringe 801-3900-00007-00
100ul syringe maintenance and
35
repair part 801-3900-00008-00
Sample compartment assembly only applicable to
36 801-3007-00020-00
closed tube model
Sample compartment door for sales only applicable to
37 801-3007-00021-00
closed tube model
Sample compartment door for only applicable to
38 801-3007-00022-00
bidding closed tube model
only applicable to
39 801-3007-00023-00
Predilute adapter closed tube model
A-2
Appendices
only applicable to
40 Adapter assembly 1 801-3007-00024-00
closed tube model
only applicable to
41 Adapter assembly2 801-3007-00025-00
closed tube model
42 Probe wipe fixing pin 801-3900-00096-00
only applicable to
43 801-3007-00026-00
Aspirate key for sales open vial model
only applicable to
44 801-3007-00027-00
Aspirate key for bidding open vial model
only applicable to
45
Tube barrier 801-3900-00094-00 closed tube model
46 Sample holder tighten assembly 801-3900-00046-00
47 Rinse cap assembly 801-3007-00028-00
48 Lyse cap assembly 801-3007-00029-00
49 Diluent cap assembly 801-2800-00018-00
Waste cap assembly (drain waste to
50
waste container) 801-3900-00020-00
51 Tube bracket assembly 801-3007-00030-00
52 Fluidic pump assembly 801-3900-00022-00
53 Gas pump assembly 801-3007-00031-00
54 Shielding box assembly 801-3007-00032-00
Maintenance and repair par of
55
volumetric tube 801-3101-00047-00
56 Waste pump filter assembly 801-3900-00024-00
57 Filter of the isolation chamber 801-3900-00010-00
58 Air filter 801-1805-00026-00
59 Pressure chamber assembly 801-1805-00006-00
60 Vacuum chamber assembly 801-1805-00005-00
Customized mini tee electromagnetic
61
valve maintenance package 801-0030-00001-00
Customized Two-way mini
62 electromagnetic valve maintenance
package 801-0030-00002-00
63 Back board connector package 801-3007-00033-00
64 Tubing package 801-3900-00083-00
65 Thick 50 tubing package 801-3900-00097-00
66 Thin 50 tubing package 801-3900-00098-00
67 1.5 TEFLON tube package 801-3900-00099-00
68 3603 thick tube package 801-3900-00100-00
69 MPF tube package 801-3900-00101-00
70 Middle silica gel tube package 801-3900-00102-00
Middle silica gel transferring tube
71 801-3900-00103-00
package
A-3
Appendices
A-4
Appendices
A-5
Appendices
A-6
Appendices
B-1
Appendices
12
3) The dashes marked with in the following diagram indicates the connection of closed
tube model;
4) The rest of the connections are the same for closed tube model and open vial model;
5) See Appendix A.3 for the details of the list of cable codes.
6) The electricity connection diagram of the analyzer is shown as follows.
C-1
Appendices
C-2
Appendices
D Fluidic Diagram
D-1
Appendices
E-1
Appendices
Adding diluents to the WBC bath and the RBC bath, cleaning the
Diluent syringe (10ml)
sample probe and adding diluents to the probe wipe
E-2
Appendices
F Tubing
F.1 Fluidic Disposition Chart
C21 DILUNET
T47 T48
T2
RINSE
J5-T20-
J6
SV2 T49
SV1 SV13 J3-T56-
T3
J4
SV4 SV7
SV5
J9-T64-
SV3
T34 J10
C26 GF3
C4
C16 T31 T15 T14
T35 T53 Rinse
GF4
container
SV6
T32
GF1
SV8
C3
C13 C15 T13 T12
T30
T33 T39
GF2
Volumetric
T54 Lyse
tube 1
Rinse bottl
Pressure detectin e
Pressure sensor C22 C24 g
sensor T85 T81 sensor
T50
T40 T87 T83
SPB T68 T28 RBC WBC
T51 bath bath
T79 C27 T88 T82T84
T52
PC Probe wipe T97 C1 C2
T80 VC C23 T67 C25 T66
C14 SV14
LF
SV15 T37
T36 C20
SV9
T98 T86
T38
T6 T11 J18-T62-
GP T18 J20 SV10
SV11
T10 J1
C9 C8 J19 J21J22-T63-J24J23
7
Isolation Isolation
T41 C18 T7 C2 C11
chamber 1
C10 chamber 2
8 T77 T78
C17 T8
T42 T43
C19 T99
GF5 GF6 T9
T69 T70
Waste
interface LP SV18 SV19 SV17 SV16
T29
T29 T27 T26 T22
T24 T21
C7 C6 C5
T25 T23
Waste tank
F-1
Appendices
F-2
Appendices
41 T42 M90-100071--- C1 15
42 T43 M90-100071--- C1 15
43 T47 M90-100071--- A1 70
44 T48 M90-000025--- A4 280
45 T49 3001-10-07069 A5 400
46 T50 A21-000007--- C1 60
47 T51 A21-000007--- C1 30
48 T52 M90-100071--- C1 80
49 T53 3001-10-07069 B4 460
50 T54 3001-10-07069 B3 480
51 T55 M90-100031--- B2 950
52 T56 M90-100031--- A5 610
53 T57 M90-000025--- C6 300
54 T58 A21-000002--- B5 300
55 T60 A21-000002--- B5 180
56 T61 3001-10-07069 B1 830
57 T62 M90-000026 C3 500
58 T63 M90-000026 C4 500
59 T64 M90-100031--- A4 75
60 T65 M90-100031--- B4 80
61 T66 M90-100071--- C4 210
62 T67 M90-100071--- C3 240
63 T68 M90-100071--- C2 660
64 T69 M90-100071--- D3 160
65 T70 M90-100071--- D4 160
66 T72 M6G-020007--- B2 500
67 T73 0040-10-32301 B4 60
68 T74 M90-100031--- B4 60
69 T75 M90-100031--- B4 105
70 T76 M6G-020005--- A2 25
71 T77 M90-100071--- C4 110
72 T78 M90-100071--- C4 50
73 T79 M90-100071--- C1 200
74 T80 M90-100071--- C3 210
75 T81 3001-10-07069 C4 25
76 T82 3001-10-07069 C4 25
77 T83 M90-100071--- C4 15
78 T84 M90-100071--- C4 15
79 T85 3001-10-07069 C3 25
80 T86 3001-10-07069 C3 25
81 T87 M90-100071--- C3 15
82 T88 M90-100071--- C3 15
83 T89 M90-100031--- C4 120
F-3
Appendices
F-4
Appendices
F-5
046-001623-00
P/N 1.0