Genetically Modified Organisms

Project Engineers: Jon Faerber

Terrell Edwards, Andre Guenawan and Shogo Osawa

Date: June. 05, 2005

Introduction

Throughout history, humankind has attempted to make various things easier for

themselves by controlling the world around them. It started with the domestication of animals

around 50,000 B.C. After altering animals, as humans evolved into an agricultural based society,

they started breeding different strains of plants hoping to get the best possible plants for food.

These practices have continued throughout history, but as scientific understanding of breeding

and technology grows, the methods of going about altering plants and animals have changed.

Now, rather than breeding two similar types of plants or animals together, engineers and

scientists can directly alter the genetic sequence of the DNA of a species. This possibility of

altering plants and specifically crops for the food supply raises many ethical and possible safety

issues which need to be explored.

This paper will explore many of the social and ethical dilemmas associated with GMO's

in our food supply. Specific focus will be given to the technical aspects of genetic modification,

possible positive and negative effects of genetically modified foods, laws on genetically

modified foods in the United States. The goal by covering all of these diverse topics is to help

the reader be well informed of all aspects regarding genetically modified foods so that they can

come to their own ethical stance. We propose that the government create a law requiring the

labeling of all GMO products. This is currently done in all European nations and should also be

obligatory here in the United States. This will leave the ultimate decision regarding GMO's to be

made by way of an informed consumer choice to spend their dollar.

Technical aspect of GMO

There are several rising concerns about the upcoming push of genetically modified foods,

due mainly to the emergence of new products from GM companies. For centuries, we have been

doing our own sort of genetic modification, by manipulating certain breeds and species. One

example would be the selective breeding of plants; by selecting certain seeds with more

resistance to disease and pests than others, farmers are able to produce more crops. However,

with the introduction of genetic engineering, modifications to plants and animals no longer have

to be done through the selective breeding process. Genetic engineering has allowed the process

to speed up considerably faster, allowing farmers to produce crops that are immediately resistant

to strains of bacteria or insecticides. It also has the advantage of cross species manipulation,

providing for an unlimited number of possibilities. So what is the process behind all of this?

There are several techniques available with todays technology to modify plants and animals

through genetic engineering.

The use of genetic modification has become relatively common in todays

technologically expanding world. By taking specific long strands of DNA (genes) and inserting

them into other species of cells, it is possible for the new cells carry on useful traits. These new

cells that emerge with foreign genes are called transgenic organisms, and are also known as

genetically modified organisms (GMOs). Generally, plants can be genetically modified easily

because they can be grown from a single cell or piece of tissue. The process of genetic

engineering requires the successful completion of five important steps, each varying in length of

time to complete: DNA extraction, gene cloning, gene design, transformation, and backcross

breeding [1].
 The first step that takes place is DNA extraction. During this step, the selected gene is

extracted from an organism. The gene is then cloned thousands of times, so that it can be

successfully inserted into cells. Next, the gene is designed to be effective when placed inside a

different organism. This step is done by modifying three regions, the promoter, coding region

and termination sequence [1]. The promoter region essentially turns the gene on and off like

a light bulb switch and also specifies the number of times a protein will be produced. The coding

region is where the important DNA information is stored, and gives off the desired traits. The

termination sequence signals the end of the gene so the entire chromosome is not read, which is

important because unnecessary genes should not be read.

Transformation is where a new gene is delivered into the nucleus of a plant cell and

inserts into a chromosome [1]. The term transformation means to genetically change a living

organism. It is typically done on tissue culture, so that the cells can be grown into whole plants

with a copy of the transgene. Once the genes transfer over, they are then regenerated through a

special growth medium containing antibiotics. There are several methods for delivering DNA

into the nucleus of plant cells, such as injection, gene guns, and agrobacterium (Boucher, 1).

One type of soil bacterium, called agrobacterium, has the natural ability to transfer DNA

into plants, and has thus been called Natures own genetic engineer. Since agrobacterium

usually causes disease, those genes are removed without compromising the gene-transferring

ability. Scientists insert special genes into this strain of bacteria, and then place the

agrobacterium into a solution with calluses, which are clusters of undifferentiated plant cells.

Once in the solution, the agrobacterium work their way into the target calluses, eventually giving

rise to a new breed of plant cells [3].

 The method of genetic modification by ways of using biolistics, also known as gene

guns or the shotgun method, can be applied to any plant cell. This method works by shooting

DNA into the plant cells, using microscopic gold or tungsten particles coated with DNA. Tissue

culture cells are put in a vacuum chamber and the metal particles are propelled with high-

pressure gas, such as helium, and is released in a sudden burst. DNA that penetrates the nucleus

of the plant cell are eventually regenerated with special laboratory procedures. The gene gun

method is used where agrobacterium is not suitable for use, such as in wheat, rice, and corn [4].

There is another method of which involves injecting DNA with a very sharp needle into

cells. This has been used primarily on animals, but unfortunately has a high rate of failure.

Similar to the gene gun method, the genes from one organism are transferred to a foreign cell

through specially designed needles. In animals, the injected cell is usually a fertilized egg which

can be put back into the female uterus and develop normally.

The process of delivering DNA into the cell via electroporation uses quick pulses of

electricity. It is done by first creating and mixing a solution containing cells and DNA

molecules. By electrocuting the cells, tiny pores in the walls open up, allowing the DNA

molecules to fit through them [1]. However, this process usually requires repeating hundreds of

times before success, since there is no control as to how the gene gets inserted into the

chromosome.

Once the gene is successfully inserted, plant cells are immediately go through a special

process called regeneration. Plant cells or tissue into which genes have been introduced can be

regenerated in the laboratory by the use of appropriate plant hormones, and careful culture, into

whole plants [1]. However, there is no universal method in the regeneration of plants because

each plant responds differently. Therefore, culture and regeneration methods must be adapted
depending on both plant cell type. Shortly thereafter, they are crossbred with non-modified

plants, making a new line of plants which are again bred with the hybrids, until the offspring

have 99+% of the transgene [1]. After that, scientists check to see if the inserted genes work, and

monitor the future offspring of the plants.

One important thing in this field of technology is the use of marker genes. New genes

that are introduced into plant cells have beneficial characteristics, such as the ability to produce

their own insecticide or increased nutritional value. The problem with genetic engineering is that

the success rate isnt very high; only a fraction of genetically modified cells take up the new

genes. Marker genes allow scientists to tell if the new genes is present in a cell or not, giving

them identifiable characteristics in the early stages of cell development; this saves scientists time

and resources [4]. For example, some marker genes give cells the ability to withstand antibiotics

and herbicides. When they are treated with antibiotics or herbicides, these cells will survive,

while the untreated ones die. Other marker genes can turn cells into a distinct color when treated

with chemicals, or glow under a certain kind of light [5]. Marker genes are essential in genetic

engineering because it provides a powerful tool to the scientist: determining whether or not a cell

has been successfully modified.

 Among crops that are genetically modified in the United States, soybeans, corn,

and cotton are the most commonly produced [6]. The goal of most biotechnology

products are to tolerate herbicides, resist pets, improve color and flavor, increase

nutritional value, and provide longer storage times. For example, the process behind

creating a new breed of corn that can withstand insects can be done in a few steps. By

inserting a gene from the bacterium Bacillus thruingiensis (Bt) into plants, it instructs

them to produce a protein that is toxic to some insects, such as caterpillars, but harmless

to most other creatures. First, the gene from the Bt bacterium that directs cells to produce

a toxic protein to certain insects is isolated, then inserted with the marker

gene into plant cells by method of very sharp needles. Once that is

done, scientists create a condition where only the cells that have taken

up the genes will survive, such as by exposing the cells to an antibiotic.

Once determined, the new cells are allowed to grow into plants, where

they eventually produce seeds for companies to collect and redistribute.

With such a promising future for genetic engineering, the applications are

limitless. On the horizon are bananas that produce human vaccines against infectious

diseases such as Hepatitis B; fish that mature more quickly; fruit and nut trees that yield

years earlier, and plants that produce new plastics with unique properties [7]. As

researchers gain more information on this subject, GM product development will

continue to progress in unprecedented ways, possibly alleviating important issues such as

world hunger and crop failure.

Benefits of Genetically Modified Foods

With an ever increasing global population, massive 3rd world hunger, and the

health risks of pesticides, it would seem as if genetically modified organism (GMO's)

would be seen as a hero coming to the world's rescue. Instead however, many people see

GMO's as the greatest threat ever to human civilization [8]. But genetic engineering or

biotechnology is creating new novel strategies to help scientist solve the problem of how

to feed the world. It has been estimated that a child dies every two seconds world wide

from starvation; this does not even take into account the number of people who are mal

and undernourished. We have the technology to transfer potentially any gene from any

organism on the planet to another organism. There is a great promise in the use of this

technology to benefit not only the farmers, but also societies worldwide.

The growth in agriculture production has increased since genetic modification

first became available. As an example: corn, wheat and protein production has increased

333%, 136% and nearly 300% respectively, according to The National Research Council.

Corn is the most important and widely grown grain in the United States. As Noel

Vietmeyer of the National Academy of Science pointed out, corn does much more than

just feed America, You rely on corn products each time you read a magazine, walk

across carpet, mail a letter, eat steak, drink beer or a soft drink, eat candy, chew gum, or

take an aspirin." Among the many strengths corn has, it also has a major fatal weakness,

it cannot reproduce without human aid. Its tight husk prevents the corn kernels from

escaping and reaching the soil to germinate. It is also vulnerable to many pests and

diseases, and corn requires a lot of nutrients.

 Some opportunities to use GMO's for good is: creating plants better resistant to

weeds, pest and other diseases such as corn, foods with better texture, flavor and

nutritional value, produce with a longer shelf life for easier shipping, bigger yields to

create more efficient use of land, less uses of herbicides and other pesticides, and finally

GMO's can create an essential sustainable way to feed the world.

In the United States we have already begun to grow our first generation of

transgenic herbicide and pest resistant crops. This has allowed farmers to not only use

fewer pesticides, but the ones they are choosing to use are more environmentally friendly.

It is also hypothesized that future generations of transgenic crops will lead to the creation

of foods that can improve human health [9]. We should not be afraid of biotechnology.

Humans, plants and animals are more than just our genes, changing one or two genes do

not make food products unacceptable for consumption.

Positive Environmental Impacts of GMO's

Soil salinity has become a major problem in all agriculture especially in the San

Joaquin Valley [10]. Salts have built up due to a decrease in the water table, poor

drainage, and topical irrigation [11]. The increase in salinity has made crops less able to

grow and in some cases unable to grow at all [10]. The pictures in figure one and figure

two show areas of salt concentration in the San Joaquin Valley as a result of irrigation

practices.
 Areas of salt
concentration

(Figure 1. A cornfield in the San Joaquin Valley 15 miles north of Kettleman City along

Highway 41 showing salt damage.)

Water holding area

Areas of salt
concentration

(Figure 2. Soil just outside agricultural water holding land in the San Joaquin Valley

20 miles north of Kettleman City along Highway 41. The soil is now white because

of significant amounts of salt.)

 Decreasing soil productivity in a nation requiring the diminishing agricultural

land to be more productive will not allow enough food to be grown for the globally

expanding population. Thus we need to research the possibility of using the genes of salt

tolerant plants species in our agricultural crops.

Mangroves are one such plant species, which may be able to provide several

options to decrease the amount of salinity within the soil. Mangroves have the unique

ability to bring in salt water through their roots, remove it from the water, and release the

salts through their leaves where wind carries it away. It may be possible to remove some

of the salts in the soil by growing mangroves in areas of high salt content or by isolating

the genes that allow them to grow in areas of high salt concentration and placing them in

our traditional field crops.

Plants are being classically bred for salt tolerance but nothing has been successful

[12]. An alternative to plant breeding is to genetically modify plants to be salt tolerant.

Salt tolerant plants may contain genes vital to genetically modify crop plants to be salt

tolerant [12]. Mangroves contain genes allowing it to tolerate and live in saline

conditions. A gene from the grey mangrove, Avicennia marina, has been genetically

implanted into a tobacco plant [13]. The plants surviving the gene transfer show an

increase in the ability of the tobacco plant to tolerate salt stress as well as showing

tolerance to other ionic stresses [13]. It may be possible to use the gene found in the

grey mangrove as well as find other mangrove genes allowing it to tolerate salt and

transfer them to food crops. Food crops with the ability to tolerate salty soil would

potentially be able to remain productive in the San Joaquin Valley

Creating a Sustainability through GMO's

Food in the U.S. is relatively inexpensive, abundant, safe and readily available

because of the success of modern plant breeding and genetic engineering. The growth in

agriculture production has increased since genetic modification became available.

Though, the American food supply may be on the verge of collapse as depletion of crop

gene pool continues. Among the less fortunate people of the world catastrophic

agriculture collapse have already taken place.

Some of the most exciting advances in genetically altered plants are for non-food

sources. Edible vaccinations are one such area. It has the potential to provide more

convenient, less costly immunization strategies. Dr. Charles Arntzen said, "The dramatic

impact of modern vaccines is not reaching the developing world where it is most

needed." There is a lack of equipment needed for making, storing and delivering vaccines

in these under developed nations, and also a cultural barrier that impedes the acceptance

of injection-based immunization. What if people were able eat foods that where part of

their normal diet, but that could also immunize against diseases?

This question has lead to scientists pursuing the creation of food products, which

would protect people from cholera and diarrhea. These two are the leading causes of

infant deaths in developing parts of the world. Already transgenic potato plants have

been produced that were demonstrated to be effective in immunizing mice against the

bacteria that cause diarrhea. The potatoes were then used in the first-ever human clinical

trails utilizing a genetically engineered food to deliver a pharmaceutical. The trials were

successful [9]. The genetic engineering of plants has the potential to provide edible plant
vaccines that could be used to immunize individuals against a wide variety of infectious

diseases ranging from cholera to potentially AIDS. Such developments have profound

implications for improving human health worldwide and save millions of lives.

It has been shown that plants have a great economic value to pharmaceuticals,

cosmetics, and other industries. As the world population continues to grow an increased

demand has been placed on our Earth's resources. Farmers sustain billions of dollars in

crop loss each year that has the potential to be controlled by gene modification. Genetic

engineering is a major innovation for agriculture providing growers with other

alternatives to conventional pesticides.

There are a number of social and economical risks of GMO's but these risks are not

a consequence of the technology but of its use. Progress with genetic engineering is no

different from any of our other technological progress. Most people in industrialized

countries are willing and able to accept a technology like the automobile. Just as many

negative things could be said about our cars as could be said about GMO's such as they

contribute to green house gases, kill about a half million people a year in the United

States alone, and adds nothing important to our lifestyle except for convenience of fast

travel. So why is genetic engineering perceived as being too risky?

Humans cannot escape the facts that we are part of the Earth's ecosystem and in

every ecosystem there are producers and consumers. Currently we have no reason to

think that genetic engineered plants are not safe to eat. People now consume about

100,000 different genes daily, and the DNA is efficiently broken down in the human

intestinal system. Though consumers want to eat what they see as natural products and

many think of genetic engineering as unnatural because it involves laboratory procedures

and field-testing. Many experts believe the only way to overcome consumer resistance to

genetically engineered foods is to clearly label products especially fruits and vegetables,

derived from transgenetic plants. The Food and Drug Administration (FDA) the agency

of the US Government that overseas food safety made its policy in May 1992 that food

obtained from transgenetic plants need not be labeled as such. The FDA decided that

what is important to the consumers is the material content of the food nutritional,

allergenic, pesticide and not the process used to generate the plant. What counts is the

end product, not the methods used to produce plant variety.

It has been argued that the world already has enough food sources to feed the world

and that the only problem has been transporting the food to the people. This is currently

the case in our dilemma of how to feed the world. However, we must continue to be on

the forefront with our research on new sustainable ways to feed the ever-expanding

current populations. Our current methods of commercial mass production agriculture are

not sustainable in the long run. We have poisoned our soils and waters to the point that

previously fertile lands are no longer productive. It is our duty to further expand our

research on GMO's, as this may be the only way to feed our children in the future.

Negative Aspects of GMOs

The use of genetically modified plants and animals has already become

commonplace in todays society without many people being aware of it. The lack of

consumer consent in the choice to eat genetically modified foods creates an ethical

dilemma. In an online article Super Organics from Wired by Richard Manning, he

discusses genetically modified organisms and new, more natural ways of altering plants.
Manning reveals that as much as 70 percent of food prepackaged in a normal grocery

store contain genetically modified foods, particularly corn and soybean[s] [14]. When

in a store there is no way of identifying which foods are genetically modified. The only

possible exception is those foods clearly labeled as organic are not modified, unless the

crops have unknowingly been contaminated. To further complicate the issue, some of the

modified foods found in stores were never intended for human consumption. One

particular strain of genetically modified corn called StarLink corn was designed

specifically for pig feed but has found its way into the national corn supply. In a Mercury

News article titled Banished biotech corn not gone yet by Paul Jacobs, he discusses

StarLink corn. Jacobs states that a program by the federal government to test corn has

found traces of StarLink corn in more than 1 percent of the corn tested from various

suppliers and growers of corn in the last year [16]. The proliferation of genetically

modified foods in the food supply has grown and shows no sign of stopping.

A majority of consumers do not want genetically modified foods. This fact was

clearly revealed by the public response to the Flavr Savr tomato. Flavr Savr was a brand

of genetically modified tomato created by Calgene, which had the gene removed that

caused the tomato to decay (in order to spread its seeds). Without this gene, the tomatoes

were able to ripen on the vine and still remain firm during transport to the markets where

they were sold. Traditionally tomatoes are picked before ripening while still green and

allowed to ripen during transportation. Despite being genetically engineered, Flavr Savr

tomatoes turned out to be less resistant to pests and easily caught diseases, which made

the crops even more costly to grow. When Flavr Savr tomatoes were released, there was

a large public backlash against genetically modified foods. The term Frankenfood was
generated to describe any engineered foods. Public groups like the Pure Food Campaign

stalled the US Food and Drug Administrations aproval of the sale of Flavr Savr tomatoes

for over three years, and by the time the tomatoes were released many people refused to

purchase the modified food. The refusal to buy Flavr Savr tomatoes was both due to their

increased price, as well as being genetically modified. This led to the bankrupcy of

Calgene, which was eventualy bought up by a larger agricultrual company, Monsanto. In

many countries in the world, there are laws either banning the sale of genetically

modified foods or requiring the labeling of foods that have been genetically altered. The

large agricultural companies in the United States have used their financial backing of

members of congress to prevent any laws restricting modified food from passing in

America. This pressure applied on the government is another tactic used by large GMO

companies which raises ethical concern about Tran genetic foods. The companies stance

against labeling is due to the fear that such laws would hurt their sales when people avoid

modified foods.

Another example of the desire by the populace to not have genetically modified

foods was demonstrated in 2004 when Monsanto announced it would not market

genetically modified wheat. In a BBC News article titled Monsanto drops plans for GM

wheat it is stated that due to customer resistance Monsanto would drop their efforts to

grow a version of Roundup Ready wheat. While they market other Roundup Ready

products it was found that wheat was too readily identifiable with common foods such as

bread which most consumers found disturbing [17]. This reveals that Monsanto knows

that consumers do not want their genetically modified products yet they willing to

continue to push the products when the consumers are not well informed. This lack of
respect for persons and the ability to make fully informed choices on the food they eat

shows bad faith in the genetically modified food industries. One of the most important

ideals when making ethical choices is letting those who might be effected make a well

informed choice with full informed consent.

This attack against the consumers informed consent upon knowning what they

are eating has further come under attack. An attempt to undermine the ability of the

organic label was brought forth in 2003. According to an article True to its roots in the

Sacramento Bee there was an attempt by GMO companies that even animals fed up to

15% of genetically engineered food should still be able to be labeled as organic [15].

This attack further demonstrates the desire to keep consumers in the dark about what they

actually are consuming.

One of the most common claims about genetically modified foods is that they are

better than their regular counterparts. This claim is often backed with a false statement

that modified crops require less pesticides and herbicides than traditional crops would

require. The worlds largest supplier of genetically modified seed for crops is Monsanto,

which happens to be one of the larger producers of pesticides and herbicides. Monsanto

owns scores of patents on different genetically modified seeds for various types of plants.

One of their popular products is Roundup Ready Soy. This is a modified version of the

soy plant designed to resist the Monsanto made herbicide roundup. Now, rather than

specifically spraying specific plants in a field of soy, the entire field can be crop dusted

with roundup. An average of three times as much Roundup is being used in these

Roundup Ready Soy fields. While this requires less manual labor in money in farm

workers it leads to an increase in funds towards Monsanto. This creates another group of
people who are affected by the choice to use GMO foods, the farm workers who are

losing their jobs in favor of extra chemicals. In an online article by Eva Cheng titled

"Genetically modified food: Bush promotes a `biological time bomb,'" she discusses the

way large corporations have pushed modified foods and how many scientists agree they

are dangerous. Seventy-five percent of GM crops are genetically manipulated to be

herbicide tolerant (but usually only to brands produced by the same multinational

corporations) and to be cultivated with heavy doses of the designated herbicide so that

everything else is killed but the GM crop [18]. The use of pesticides and herbicides in

fields has been well documented as unhealthy due to the many ways it effects the

environment as well as human consumption when the food product is eventually eaten

and still contains traces of the chemicals.

Another common claim is that genetically modified plants are less expensive to

grow and increase the productivity of farmers. This is a claim put forth by the

agricultural companies performing the modifications since it encourages farmers to buy

their products despite the fact that, many times costs raise rather than decrease. Richard

Mannings article Super Organics, which discusses the Flavr Savr proves to be a prime

examples of this. Over two hundred million dollars was invested in creating these

tomatoes and almost none of the investment was able to be reclaimed as the product was

a bust [14]. Even successful products like Roundup Ready Soy increase the cost of

farmers production by requiring more herbicides. Each year, new modified seed must be

purchased from the agricultural companies again to ensure that the crops will be the same

genetically modified strain. This ensures repeat business for the companies from farmers

who want to grow modified plants. The Independent Science Panel performed a study
about genetically engineered foods and published a report titled The Case for A GM-

Free Sustainable World. They state that, GM crops have cost the United States an

estimated $12 billion in farm subsidies, lost sales and product recalls due to transgenic

contamination. Massive failures in Bt cotton of up to 100% were reported in India [19].

An article on Organic Consumers titled Bt Cotton Fails Again in India goes into more

details about the crop failures in India. While the Bt cotton was resistant to bollworms it

was more susceptible to other forms of failure. While non-modified plants were thriving

all the Bt crops failed. This lead to an alarming rate of farmer suicide to collect on

insurance due to ruined livelihoods in the loss of farms and crops [20]. The only

financial benefit from modified plants is to the companies producing them and the

products that accompany the modified seeds, not to the consumers or farmers.

A major ethical consideration about the genetically modified foods is about the

amount and quality of testing preformed on the foods. Genetic engineering is a relatively

new field of science, and the long term results of modification are not clear. To be

ethically responsible for their product warning labels should be provided about the lack

of long term testing. Monsanto and other companies have started testing on the possible

impacts of these foods but when unfavorable results start appearing these tests are pushed

aside losing funding and other tests which dont show negative results are given more

funding. This extreme bias in testing raises the concern of in whose interest these tests

are being preformed, those of the public or those of the companies. Testing has been

preformed but there has been no unbiased long term testing preformed on the foods

leaving a void of information needed to accurately determine the safety of GMOs as

food.
 Another major ethical issue is once the modified plant has been planted in nature,

there is no way to remove the modification from the wild. This can have adverse effects

on the environment which is a growing concern among the majority of the populace.

Pollen from modified plants spreads and will infect more plants with this modification

without any human help. StarLink corn has already been a prime example of this. Once

released, despite attempts at controlling it, there is little that can be done to prevent the

spread of the modification. In the Independent Science Panels study about genetically

engineered foods titled The Case for A GM-Free Sustainable World, one of the things

revealed in this report is High levels of contamination have since been found in Canada.

In a test of 33 certified seed stocks, 32 were found contaminated [19]. Now, even those

who think they are growing natural products could possibly have crops that have been

contaminated. While there is concern about how fast the modifications spread, there are

other potential long term results that are already showing up. These modifications are

also spreading to other varieties of plants; already, weeds featuring the herbicide resistant

gene have starting appearing in Canada and parts of the United States. As these genes

spread, nature tries to adapt to compensate. Insects have been found that are resistant to

the BT gene inserted into corn and cotton in order to kill off pests. The ability of the

modified gene to spread to other plants and their effect on surrounding species can lead to

the introduction of super viruses and other unknown combinations. The environmental

impact of genetically modified foods leaves many environmental ethic questions to be

considered.

The issue of spreading genetically modified pollen spreading was also

demonstrated in Canada. Monsanto was growing some genetically modified rapeseed

which it held a patent for near an organic farmers crop. Naturally pollen spread between

these two fields and the organic farmers crop was contaminated. When Monsanto found

out about this they sued the farmer for growing patented crops without paying Monsanto

for the seed. This legal battle made its way through the Canadian legal system all the

way to the Canadian Supreme Court. In a BBC News article Monsanto wins Canada

seed battle it is stated while the Canadian supreme court over turned a lower courts fine

on the farmer that the farm be turned over to Monsanto [21]. This case has become a

rallying point of those opposed to genetically modified foods as the unethical and one

track mind towards monetary benefits that Monsanto has shown.

Another ethical concern raised in the use of genetically engineered crops is the

safety of those who consume the final product. The Bt toxin that is used in most non-

herbicide resistant strains of genetically modified plants was taken from the Bt bacteria.

This toxin is designed to kill pests that eat crops, to replace the use of pesticides. Since

the Bt toxin is inside the actual plant, there is no way it can be washed off or removed

before human consumption. Allergies and other responses have been found in many

people who eat these foods. These people with food allergies towards engineered are left

with no alternatives as the use of genetically engineered crops spread and no labeling is

preformed. As stated earlier, crops designed for pharmaceutical purposes are being

grown. Rather than produce the pharmaceutical products in labs, it has been found more

cost effective to introduce a gene into a plant and let plants grow the pharmaceutical

product then harvest it from the plant or simply be used as feed. As the pollen spreads,

genes from these pharmaceutical plants have made it into the food supply. These are

essentially drugs inside of the food that affect the immune system and are being given to
people who do not require them. The over use of, as well as unnecessary,

pharmaceuticals has been well documented as harmful towards people, particularly

towards young children and infants. These drugged foods are more commonly being fed

to animals that are raised to be slaughtered and consumed by humans. Meats as well as

plants now contain antibiotics that limit the ability of other antibiotics to treat illnesses

when actually required.

Foods, specifically plants containing genetic modifications are already common in

the American marketplace. The widespread use of genetically modified food has, for the

most part, been hidden from public view due to the large backlash the public has against

frankenfoods. The first step in helping solve the problem is to require all foods known

to be derived from genetically modified sources to be clearly labeled. While it is difficult

to determine which foods have been unknowingly contaminated, labeling allows the

consumer to make the choice whether to support genetically modified foods or not. It

will also raise public awareness that these foods are out there and how it may be affecting

them. For those consumers currently concerned about modified foods, their only choice

is to buy organic foods. Even organic crops and food sources are being threatened by

pollen from genetically altered crops. The demand for organic food has consistently been

on the rise for the past few years.

Genetically modified foods have not served any benefit to humankind or the

environment, other than a few individuals greed. The use of genetic engineering in the

food supply has many ominous problems that would require long term testing before it

should be considered. For now genetically modified products provide no benefit towards

consumers or farmers, and the practice should be stopped. This does not necessarily
mean that genetically modified foods hold no potential for good use, just needs to be

exercised with extreme caution and for the good of all people not the power of a few

individuals. While the end of GMO food is unlikely to happen, awareness of the problem

should be raised until more pressure can be put on the government and agricultural

companies to control the use of genetic engineering in the food supply.

Laws on Genetically Modified Foods in the United States

Unlike the EU, which has a comprehensive system in considering and controlling

the release of genetically modified foods into their market; the United States, a country

known for its health conscious people, has a very high confidence in genetically modified

foods. Since genetic engineered crops were first introduced for commercial production,

the United States accounts for 63%, 105.7 million acres of land, of all genetically

modified (GM) crops planted globally [22]. These crops include soybean, maize, cotton,

and canola. In addition, it is estimated that 70% of products on U.S. grocery shelves

include GM products [7]. They are widely available and generally accepted by most

consumers. A recent study on March 1999 by the International Food Information Council

shows that 77% of Americans would be likely to buy products that had been genetically

engineered [23].

Another study shows however, that in 2001, 88% of Americans are concerned

about the nutritional content of their food. The number of consumers who have changed

eating habits due to health and nutrition concerns rose to 72 percent, the highest

percentage in the last four years [24]. Therefore, it seems that most of Americans want

to be healthy, but at the same time, they are still accepting genetically modified products.
Do we really trust our health to the Food and Drug Administration (FDA) or are we just

being ill-informed or kept in the dark genetically modified foods that are now extremely

obtainable in the market?

There are three federal agencies that are responsible with the release of GM food

plants in the United States. They are the Food and Drug Administration (FDA), the

United States Department of Agriculture (USDA), and the Environmental Protection

Agency (EPA). The FDA has the responsibility of regulating the safety of most domestic

and imported foods in the US market, except meat and poultry, which are handled by the

USDA. The EPA meanwhile has jurisdiction over activities that can potentially harm the

environment [26], especially on pesticides used in or on foods. Of these three agencies

however, the FDA is in charge for most of the GM foods that is available in the USs

market.

The FDA is one of the United States oldest consumer protection agencies. It

regulates over $1 trillion worth of products sale annually. It is also a public health agency,

in charge with protecting American customers by enforcing the Federal Food, Drug and

Cosmetic Act and several related public health laws [25].

In the food safety sector, the FDA makes sure that the food consumers consumed

is safe, and wholesome. The agencys scientists would need take food samples and test it

for any excessive presence of pesticides and residues before it is released to the market s

[25]. If contamination is ever detected, an appropriate corrective measure is taken. The

agency however, does not evaluate the processes used to manufacture these foods. In

other words, for a GM food, the FDA does not consider the fact that the sources of these

foods are genetically modified organism [26]. The FDA would only require a label if they
meet one of these criteria: First, if a GM food contains substantially different nutrient

content than its conventional counterpart, it requires labeling. Second, if the product is a

novel food, i.e., one never before produced. Third and fourth, those GM foods containing

a potential allergen or increased level of toxicity also must be labeled [28].

The first commercially modified food crop was FlavrSvar, a tomato that was more

resistant to rotting, created by Calgene [22]. In 1994, after it had passed the FDAs

voluntary testing for safe human consumption, Calgene released it to the market without

any labeling indicating that FlavrSvar was actually genetically modified. The FDA

allowed this as FlavrSvar was still actually a tomato with the same amount of vitamins,

protein and mineral as non-modified tomatoes and did not constitute any health hazards

(allergen). Although FlavrSvar did not hit the market very well because of poor flavor,

the FDA later received many criticisms for not requiring labeling to FlavrSvar. This is

also true that up till now, the FDA, despite increasing pressure, does not require most GM

foods such as Bt potatoes that are readily available in grocery store to be labeled; simply

because they are just equivalent to the non-GM version and therefore their method of

production is irrelevant.

Since the process of testing the safety of GM foods by the FDA is voluntary for as

long as the new product is not significantly different from its traditional counterpart, it

is not surprising that if most of the products sold in the market now is categorized as

substantially equivalent and safe by their manufacturers. These products could have too

few health and environmental safety checks and therefore too much information being

covered to the public. A report by the Consumer Federation of America Foundation

concluded that this flexible law by the FDA includes huge loopholes that could allow a
potentially dangerous GM food to enter the food supply but still left the FDA blameless if

that food is found to be unsafe [27].

A recent newspaper report on March 2005 said that one unapproved GM food

actually went into our food supply. It was the genetically altered corn seed, called Bt 10.

The seed was distributed by Syngenta. The seed was modified with a gene from the

pesticide-like bacterium. It was sold accidentally to some US farmers for four years

and has occupied for around 37,000 acres of land since then. Although most of the corn is

for industrial and animal use, Syngenta spokeswoman Sarah Hull said that It may have

gotten into the food supply [29]. Though according to the USDA and EPA that Bt 10 is

safe, the fact that the federal government kept this news in secret for three months

undermine the public confidence in the growing field of genetically modified crops. In

addition, if the seed was safe in the first place, why was it not in the approved list of GM

foods?

Conclusion

There are many ethical issues related to the growing and consumption of

genetically engineered crops. They hold potential to greatly increase the nutritional value

of food as well as the productivity of crops, while at the same time provide many safety

as well environmental concerns. These decisions need to be looked at by all of humanity

since everyone is directly affected by the choices. While each person can read these

details and come to different conclusions on the value of genetically engineered foods as

well as the ethical choices being made by the companies in charge of producing these
foods. The ultimate choice on genetically engineered foods should be placed onto a well

informed consumer not held in the dark by those in power of the government and large

corporations which may not have the general publics interests as their primary goal.
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[24] Google Answer, Are we health conscious shoppers?

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