Department of Chemical Engineering

University of San Carlos

Nasipit, Talamban, Cebu City

SYLLABUS
Course Information Faculty Information
Course No. : CHE 426N Name : Dr. Camila Flor Y. Lobarbio
Course Title : Introduction to Biotechnology Office : ChE Department
Credit Units : 2 Email : camilaflory@yahoo.com
Pre-requisites : CHEM 31 Organic Chemistry II Phone : +63-32-344-6783
Term : 2nd Semester, SY 2015-2016 Consultation Time :
Schedule : 9:30 AM 10:30 AM (TTH)
Course Description
In this course, you will learn the fundamentals of microbiology including types of cells, their physical and chemical structure.
Since cells and enzymes are essential to life, you will learn their roles, production and the different factors that affect their
activity. It is expected that you will be able to apply the principles of fermenter design as well as the techniques for altering cells
so that their metabolic capability may be enhanced.
Course Outcomes (CO) Targeted Program Outcomes (PO)
Upon completion of the course students should The course is enabling to your achievement of:
be able to:
[PO1] Ability to apply knowledge of mathematics and science to the
CO 1: Explain the structure, organization, function, general practice of chemical engineering and in at least one
genetics and metabolism of living matter in molecular specialized field of application; and
terms; [PO5] Ability to identify, formulate, and solve chemical engineering
CO 2: Define the role of living cells (and the problems.
substances derived from them) in some biochemical
reactions occurring in nature; The course is introductory to your achievement of:
CO 3: Critique current methods/techniques for the
production of commercially important biochemical [PO9] Ability to engage in life-long learning and to update oneself
products; and continuously with the current trends and development in a chosen field
CO 4: Apply the principles governing cell and enzyme of specialization; and
kinetics in the design of industrial fermenters or [PO10] Understanding of the broad economic, environmental, societal
bioreactors. and global impacts of chemical engineering solutions.
Assessment of Outcomes
As evidence of having achieved the outcomes, students must successfully perform tasks and produced quality outputs.
Formative Summative (Rubric-Based)
For CO1-CO4: Concept Quizzes (CQ) For CO1: Midterm Examination-Multiple Choice (ME)
Molecular Structure Picture Album (PA)
For CO2 & CO3: Paper Critique (PC)
For CO4: Fermenter Design Project (FDP)
Final Examination-Problem Based (FE)
Assessment & Evaluation Rubrics (See Annex)
Output/Performance Rubric Title
Concept Quizzes (CQ) Picture Album Report Rubric
Midterm and Final Examination (ME and FE) Paper Critique Rubric
Molecular Structure Picture Album Report (PA) Fermenter Design Project Rubric
Paper Critique (PC)
Fermenter Design Project (FDP)
Grading System
Your grade for the course is computed based on both formative and summative assessment data. The computation is detailed
below.
Grade Component Weight Computation
CQ Average Grade (15%) CQ Average Grade x 0.15
ME Grade (15%) ME Grade x 0.15
FE Grade (25%) FE Grade x 0.25
PA Grade (10%) PA Grade x0.10
PC Grade (15%) PC Grade x 0.15
FDP Grade (20%) FDP Grade x 0.20
Total Grade
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Passing Grade: 3.0
Condition for Passing: ME and FE Grades must each be 3.0 or better.
Course Structure
Course Topics Week Learning Activities
Outcome
Introduction to Living Systems 1-4
CO1 Cellular basis of life: history of biotechnology:
organization of cells; biomolecules
Cell Kinetics and Fermenter Design 5-12
Cell growth and kinetics: terminologies;
CO2 & CO3 growth cycle for batch cultivation; stirred tank Classroom activities include series of lectures
fermenter; ideal continuous stirred tank and discussions complemented with problem-
fermenter; industrial application of cells solving and exercises. Lecture notes and hand-
outs are provided to facilitate guided learning.
13-18
Enzymes and Enzyme Kinetics
CO2 & CO3 Simple enzyme kinetics; enzyme reaction
with simple kinetics; inhibition of enzyme
reactions; other influences of enzyme
activity; industrial application of enzymes

Learning Resources

BOOKS
1. Bourgaize D, Jewel TR and Buiser RG. Biotechnology (Demystifying the Concepts). Addison Wesley Longman, INC. 2000.
2. Shuler ML and Kargi F. Bioprocess Engineering Basic Concepts. Prentice-Hall, Inc. NJ, 2002.
3. Lee J. Biochemical Engineering. John Wiley and Sons, USA, 1995.

Articles/Research Papers
To be selected by the class

Lecture Materials
Lecture Materials are supplied regularly.

Course Requirements and Policies

A. SCHEDULE OF LONG EXAMS (must be followed strictly unless otherwise announced)

First Long Exam December 5 7, 2016

Second Long Exam (Midterm Exam) January 23 28, 2017
Third Long Exam February 20 22, 2016
Fourth Long Exam (Final Exam) March 20 25, 2017

B. STUDENT PORTPOLIO (must be in short-sized folder with fastener and plastic cover)
Students are required to design, develop, and maintain a biotechnology portfolio, which can demonstrate and integrate the
students knowledge of the course beyond the required assignments and exams. Professional presentation, clarity, brevity and
creativity are important. This should contain the following:
a. 2-sets of well-critiqued and commented original and published (in year 2005 onwards) research paper pertaining to
biotechnology.
b. Compilation of all quizzes, exercises, exams and assignments done for the course.

C. TEST AND EXAMINATION

a. Long exams will be announced.
b. No permit, no exam.
c. Bags, telecommunications gadgets and other things should be stowed away from the students (e.g. placed on the
platform) during exams. Turn off mobile phone or put it on silent mode.
d. A student is not allowed to go out during exams.
e. If a student misses two (2) long exams, then he/she shall get a final grade of NC.
f. If a student misses one (1) long exam, unexcused, then he/she shall get a grade of zero in that exam.
g. If a student comes in 15 minutes late during exams, then he/she cannot take the exam anymore.
h. A student shall only be given a special exam for a missed exam if and only if for a very valid

D. OTHER TASKS: ASSIGNMENTS, SEATWORKS, & EXERCISES

a. Solved problem sets must be written on a short-size bondpaper.
b. All members who participated in a given group activity must affix the signature on the answer sheet.

E. GROUP WORKS
a. Each group must appoint a leader.
b. The appointed leader is responsible in collating the assigned or solved problems and in submitting them.
c. All submitted group work must bear the name of the member and the corresponding signature of each member as well

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 as a description of the contribution of each member.
d. A member who does not affix his/her signature on the paper where the work is written is considered to be absent or
non-participating in the said activity and shall be a given a grade of zero in the said activity.

F. CLASSROOM DECORUM, ATTENDANCE, & UNIFORM

a. The policies written in the Students Manual shall be followed.
b. The use of your mobile phone or tablet is restricted to viewing documents only and not for calling, texting, listening
music and taking a selfie.

G. SUBMISSION OF COURSE REQUIREMENTS

a. Out of classroom hours
i. The cutoff time for submission is 5:00 PM. Submissions made later than 5:00 PM will not be accepted.
ii. Picture Album Report must be submitted a week after the midterm exam.
iii. Paper Critiques will be submitted a week before the final exam.
iv. The fermenter design project and student portfolio will be submitted during the final exam.
b. Exams
i. Exams submitted after countdown will not be accepted.

Prepared by : _____Dr. Camila Flor Y. Lobarbio__________

(Name in print & signature of Faculty Member)

Approved by : _____Engr. Luis K. Cabatingan ________

(Name in print & signature of Department Chair)

Date Approved: ____________________________________