Methadone/Lidocaine/Ketamine

IV FLUID BAG BASED CRI INFUSIONS

Kilogram based calculations (with pounds/kilogram converter)
Robert M. Stein, DVM, PC

Patient Name Date 3/12/2011

Patient Wt. 34.5 kgs lean body estimate
For pounds to kilogram conversion see bottom of calculator.
Patient weight only needed for total fluid rate & drug loading dose calculations.
Only drug dose rate, fluid administration rate, and fluid bag size determine amount of drug added to IV bag.

IV Bag Size 1000 ml

Fluid Rate 1 ml/kg/hr = 34.5 ml/hr

Drug dose rate Total drug Drug Volume Drug/ml fluids

Methadone 0.1 mg/kg/hr 100.00 mg 10.00 ml 0.100 mg/ml

Lidocaine 1.50 mg/kg/hr 1500.0 mg 75.0 ml 1.50 mg/ml

Ketamine 0.60 mg/kg/hr 600.0 mg 6.00 ml 0.60 mg/ml

Drug CRI Dose Range

METHADONE - 0.083 to 0.166 mg/kg/hr (1.4 to 2.8 ug/kg/min).

LIDOCAINE - 0.6 to 3.0 mg/kg/hr (10 to 50 ug/kg/minute).

Dogs can be given up to 3.0 mg/kg/hr (50 mcg/kg/min)
Cats should be limited to a maximum dose rate of 1.5 mg/kg/hr (25 mcg/kg/min)

KETAMINE - 0.12 to 1.2 mg/kg/hr (2 to 20 ug/kg/minute).

Loading Doses
METHADONE - 0.5 mg/kg IM, IV
At 0.5 mg/kg this patients needs a loading dose of: 1.73 ml

LIDOCAINE - 0.25 to 1 mg/kg IV

At 0.25 mg/kg this patients needs a loading dose of: 0.43 ml
At 0.5 mg/kg this patients needs a loading dose of: 0.86 ml
At 1.0 mg/kg this patients needs a loading dose of: 1.73 ml
CATS - Limit cats to 0.25 to 0.5 mg/kg loading dose
DOGS - 1.0 mg/kg is the normal loading dose

KETAMINE - 0.25 to 0.5 mg/kg IV

At 0.25 mg/kg this patients needs a loading dose of: 0.09 ml
At 0.5 mg/kg this patients needs a loading dose of: 0.17 ml

Drug Concentrations
METHADONE - 10 mg/ml
LIDOCAINE - 20 mg/ml
KETAMINE - 100 mg/ml

Maintenance Fluids Calculator

(BW kg * 30ml/24 hrs)+70ml

Maintenance Fluid Rate 1.33 ml/kg/hr = 46.0 ml/hr

Rate Multiplier 2.0 2.67 ml/kg/hr = 92.1 ml/hr

Drip Rate Converter

CRI fluid rate from above 34.5 ml/hr Value from F14 above
Drip set (drops/ml) 60 drops/ml
Seconds per drop 1.74 sec/drop
Drops per second 0.58 drops/sec

Weight Converter
For those that prefer to weigh in pounds. You will need to manually transfer the patient weight in kilograms into the patient weight
field above - it will not be transferred automatically.
Enter patient weight in pounds 13 lbs = 5.9 kgs
Note - patient weight is only needed for fluid delivery rate calculations. The drug dose rate, fluid administration rate, and fluid bag
size determine the amount of drug added to the IV bag.