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PATHOPHYSIOLOGY

Mechanical stress
( compression,
fusion, HPN,
rotational forces.) Aggravated by age -Decreased fluid in
due to degenerative Decreased in the annulus.
changes thus protein contents -Dehydration of the
resulted in weak (oncotic agents) annulus.
muscles. -weakening of the
annulus, thus less
Men gender are elastic, thus prone to
mostly predisposed to tearing.

-Increased uptake of
fluid in the nucleus
pulposus.
Erosion of vertebral body by -Increase pressure in
bulging disk teared annulus. the nucleus pulposus.

Irritated pain fibris

Stimulation of new
Local bone growth
tenderness accompanied by
vertebral spasm. PAIN
Ligament
thicken Accompanied by:
Increased
Autonomic responses:
tension
-inc. v/s
-papillary dilatation
Calcification -diaphoresis

Replacement of
nucleus

Results in neutral
obstruction

Decrease flow of
blood in the
affective area

Compression of
spinal nerve Numbness occurs

Impaired
mobility

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