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Downloaded from nejm.org at UC SHARED JOURNAL COLLECTION on January 28, 2015. For personal use only. No other uses without permission.
From the NEJM Archive. Copyright 2010 Massachusetts Medical Society. All rights reserved.
The New England Journal of Medicine
Downloaded from nejm.org at UC SHARED JOURNAL COLLECTION on January 28, 2015. For personal use only. No other uses without permission.
From the NEJM Archive. Copyright 2010 Massachusetts Medical Society. All rights reserved.
The New England Journal of Medicine
Downloaded from nejm.org at UC SHARED JOURNAL COLLECTION on January 28, 2015. For personal use only. No other uses without permission.
From the NEJM Archive. Copyright 2010 Massachusetts Medical Society. All rights reserved.
The New England Journal of Medicine
Downloaded from nejm.org at UC SHARED JOURNAL COLLECTION on January 28, 2015. For personal use only. No other uses without permission.
From the NEJM Archive. Copyright 2010 Massachusetts Medical Society. All rights reserved.
The New England Journal of Medicine
Downloaded from nejm.org at UC SHARED JOURNAL COLLECTION on January 28, 2015. For personal use only. No other uses without permission.
From the NEJM Archive. Copyright 2010 Massachusetts Medical Society. All rights reserved.