Global Idiopathic Pulmonary Fibrosis (IPF) Treatment Market US$ 3.

5 Billion by 2021

The global idiopathic pulmonary fibrosis treatment market expected to reach US$ 3.5 billion by 2021, growing at
CAGR 14.4% over the forecast period 2017-2021, owing to increasing drug prices and rapid approval of new
treatments.

Idiopathic pulmonary fibrosis (IPF) is a rare, but serious lung disease. According to the National Institutes of Health,
about 100,000 people in the United States have IPF, and approximately 30,000 to 40,000 new cases are found each
year. Worldwide, IPF affects 13 to 20 out of every 100,000 people. Common comorbid medical conditions found in
patients with idiopathic pulmonary fibrosis include chronic obstructive pulmonary disease, obstructive sleep apnea,
gastroesophageal reflux disease, and coronary artery disease. According to Pulmonary Fibrosis Foundation, the mon-
pharmacologic management of pulmonary fibrosis (PF) to manage symptoms and prevent future complications
includes home pulse oximetry, pulmonary rehabilitation, vaccination, weight management, and lung
transplantation. In the United States; in 2013, PF accounted for nearly half of all lung transplants performed.

Several different medications have been used for the treatment of PF. Corticosteroids (prednisone),
Cyclophosphamide (Cytoxan), Azathioprine (Imuran), Mycophenolate mofetil (Cellcept, Myfortic), N-acetylcysteine
(NAC), Nintedanib (Ofev), Pirfenidone (Esbriet, Pirfenex, Pirespa), and Proton pump inhibitors (Prilsec OTC, Nexium,
others). Some of the therapeutic approaches currently being studied include anti-fibrotic therapies, inhibitors of
growth factor proteins, stem cell therapies, and genetic research. In 2014, US-FDA approved two anti-fibrotic
medications are drugs that inhibit or reduce fibrosis in the lung: Ofev (nintedanib) and Esbriet (pirfenidone) for the
treatment of patients with IPF.

Visit Idiopathic Pulmonary Fibrosis (IPF) Treatment Market by Treatment Type - Pharmacological Treatment
(Pirfenidone (Esbriet), Nintedanib (Ofev), Generic Pirfenidone); Non-pharmacological Treatment (Oxygen Therapy,
Pulmonary Rehabilitation, Mechanical Ventilation, Lung Transplantation, Other Non-Pharmacological Treatment);
Patients by Disease Severity (Mild, Moderate, Severe); Drug Pipeline Analysis (AEOL-10150, Lebrikizumab,
Tipelukast, Tralokinumab, FG-3019, Simtuzumab, BMS-986020, AF-219, SAR156597, BG00011, PRM-151, PBI-4050)
and Forecast 2017-2021. The global idiopathic pulmonary fibrosis treatment market research report provides market
size (Revenue USD Million 2014 to 2021), patient numbers by disease severity and by country (U.S., Japan, U.K.
Germany, France, Italy, Spain, 2014 to 2021), market share analysis, growth trends and forecast (CAGR%, 2017 to
2021). The global idiopathic pulmonary fibrosis treatment market research report is further segmented by geography
into North America (U.S., Canada), Latin America (Brazil, Mexico, Rest of LA), Europe (U.K., Germany, France, Italy,
Spain, Rest of EU), Asia Pacific (Japan, China, India, Rest of APAC), and Rest of the World. In addition, the global
idiopathic pulmonary fibrosis treatment market report provides the detailed market landscape (market drivers,
restraints, opportunities), market attractiveness analysis, and market profitability analysis by key products and
regions or countries. The report also tracks the major competitors operating in the global market by company
overview, financial snapshot, major products, technologies, services offered and recent developments. Major
players operating in the global idiopathic pulmonary fibrosis treatment market and profiled in this report include
Aeolus Pharmaceuticals, Baxter International, Biogen, Inc., Boehringer Ingelheim, F. Hoffmann-La Roche, FibroGen,
Inc., Gilead Sciences, Inventiva Pharma, MediciNova, Inc., Merck & Co. (Afferent Pharmaceuticals, Inc.), Promedior,
Inc., Prometheus Laboratories, Inc., and Shionogi & Company.

1. Treatment Type
1.1. Pharmacological Treatment - Drug (Brand)
1.1.1. Pirfenidone (Esbriet)
1.1.2. Nintedanib (Ofev)
1.1.3. Generic Pirfenidone
1.2. Non-pharmacological Treatment
1.2.1. Oxygen Therapy
1.2.2. Pulmonary Rehabilitation
1.2.3. Mechanical Ventilation
1.2.4. Lung Transplantation
 1.2.5. Other Non-Pharmacological Treatment

2. Patients (Disease Severity)

2.1. Mild
2.2. Moderate
2.3. Severe

3. Pipeline Analysis
3.1. AEOL-10150
3.2. Lebrikizumab
3.3. Tipelukast
3.4. Tralokinumab
3.5. FG-3019
3.6. Simtuzumab
3.7. BMS-986020
3.8. AF-219
3.9. SAR156597
3.10. BG00011
3.11. PRM-151
3.12. PBI-4050

4. Geography
4.1. North America (U.S., Canada)
4.2. Latin America (Brazil, Mexico, Rest of LA)
4.3. Europe (U.K., Germany, France, Italy, Spain, Rest of EU)
4.4. Asia Pacific (Japan, China, India, Rest of APAC
4.5. Rest of the World

5. Company Profiles
5.1. Aeolus Pharmaceuticals
5.2. Baxter International
5.3. Biogen, Inc.
5.4. Boehringer Ingelheim
5.5. F. Hoffmann-La Roche
5.6. FibroGen, Inc.
5.7. Gilead Sciences
5.8. Inventiva Pharma
5.9. MediciNova, Inc.
5.10. Merck & Co. (Afferent Pharmaceuticals, Inc.)
5.11. Promedior, Inc.
5.12. Prometheus Laboratories, Inc.
5.13. Shionogi & Company

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