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BASF Biocides
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BASF Biocides - protecting the world
The biocide business for Specialty Chemicals, BASF AG
BASF is one of the worlds leading suppliers of How we work for you
specialty biocides. We create products that make
life safer, simpler and more comfortable for BASFs biocides are sold through BASFs
millions of people worldwide. established network of sales offices worldwide. In
this way, we aim to offer valuable local support
Our high performance biocides are used in every and the highest standards of customer excellence.
aspect of life. From toiletries, to air conditioners
used in both industry and home, from Iceland to Working with BASF provides access to many
Equador our technology spans the globe in essential regulatory approvals. For example our
preservation and disinfection. We help to protect EPA registrations allow products and customer
the lives of millions of people across the world formulations to be sold in the USA and our
every day. approvals ensure supply to the paper industry in
the Nordic area. We are also well positioned to
Through our product range, marketing expertise, support our actives under the European Biocidal
technical and regulatory knowledge, BASFs Products Directive.
innovative biocides approach positions the
business at the very forefront of antimicrobial We believe in long-term commitment to our
technology. The marketing, technical and research products and customers and this is reflected in
and development headquarters for BASFs our substantial registrations and the data required
specialty biocide business is located in to obtain them. To this end many of our products
Nottingham. are supported with extensive safety and
environmental data packages.
Our products are made in state of the art
manufacturing facilities at Cramlington, England In addition, BASF is committed to providing the
and Ludwigshafen, Germany. In each of our highest standard of health, safety and
plants, the expert integration of process and environmental protection as part of our
energy requirements leads to manufacturing commitment to Responsible Care. We continually
efficiencies and quality production. research and innovate to produce the most
advanced products on the market.
To demonstrate our commitment to our customers,
we have made significant investment in long term At BASF, we are also constantly reviewing ways in
dedicated biocide resources within Europe, Asia which we can improve our products and services
Pacific and the USA. to ensure that we keep pace with the rapidly
changing developments in information technology.
In 2000, we established a direct presence in the BASF is harnessing these changes and ensuring
USA with a new dedicated marketing and that we are aligned with our customers
technical centre based at BASF Corporation requirements, making it more efficient and
headquarters in Mount Olive, New Jersey. Product convenient for you to do business with us.
is supplied through an integrated BASF
warehousing facility in Charlotte, North Carolina. BASFs specialty biocide products are marketed
Our US operation is part of BASF Corporations under the Myacide and Protectol trade names.
Chemical Division, situated in Mount Olive, New
Jersey.
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Introduction to the Paper Biocide Industry
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Myacide AS, AS Plus and S1/S15/S30
Biocide
Myacide AS biocide is the industrial grade of 2- Concentrations (M.I.C.) of Bronopol against six
Bromo-2-nitropropane-1,3-diol or Bronopol. It key microorganisms.
provides highly effective antimicrobial activity for
Test Organism M.I.C. (ppm)
use in diverse and demanding industrial biocide
applications, combining well-proven efficacy with Staphylococcus spp 12.5 - 50
important environmental safety characteristics. Bacillus spp 12.5 - 50
The main benefits of Myacide AS in the paper Desulphovibrio spp 12.5 - 50
industry are its proven performance as a slimicide Pseudomonas spp 12.5 - 50
active ingredient in mill process water and as an Candida spp 400
effective preservative for mill additives. The ideal Aspergillus spp 3200
physical and microbiological properties of
Bronopol place it in a new generation of products, M.I.C. data is generated according to in-house
which can be seen replacing older chemistries. methodology.
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Bronopol is compatible with a range of materials
used in the pulp and paper industry such as
retention aids, flocculants and other biocides such
as isothiazolinones. In common with other non-
oxidising biocides, strong reducing agents and
oxidising agents should be avoided. However,
Bronopol can be used alongside oxidising biocides
in systems with alternating biocide regimes.
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Myacide AS, AS Plus and S1/S15/S30
The following example (fig. 1) demonstrates the In order to support the safe use of Bronopol, a wide
efficacy of Bronopol in preserving a typical paper range of toxicological studies have been carried
mill additive based on calcium carbonate. out. The extensive nature of this database is
The procedure used was ASTM E 723-91 at particularly helpful in supporting product
pH 7.5 with a mixed inoculum of Pseudomonas registrations and answering any concerns on
aeruginosa, a second (1,2-Benzisothiazolin-3-one product safety. Bronopol is non-carcinogenic, non-
(BIT)-resistant) Pseudomonas species, mutagenic, non-embryotoxic and non-teratogenic. It
Enterobacter cloacae and Klebsiella aerogenes. is also non-phototoxic.
Myacide AS at a level of >20ppm was able to Bronopol is biodegradable and does not
control this mixed inoculum for a period of six accumulate in the environment. Due to its rapid
weeks following a single initial challenge of photolysis and hydrolysis, Bronopol will not, under
106cfu/ml and a reinoculation at 21 days. BIT at normal use conditions, cause problems to effluent
levels of up to 200ppm active was unable to control treatment plants or to the environment following
the Pseudomonas growth. discharge into wastewaters.
REGISTRATIONS
NORTH AMERICA
USA
EPA - BASFs Bronopol is approved for use in paper mill pulp and
process water, starch, pigments and extender slurries.
FDA 21 CFR. - Code of Federal Regulations. Listings are:
176.300 - Paper slimicides use.
175.105 - Indirect food contact use in adhesives.
(fig. 1) Calcium Carbonate Slurry - Bronopol Data
8 176.170 - Components of paper and paperboard in contact with
aqueous and fatty foods.
7
6 CANADA
5
Health Canada have approved the use of BASFs Bronopol as a
slimicide and granted a letter of no objection for use in paper
4
coatings intended for food contact.
3
EUROPE (EU)
2
DENMARK
1
Paper slimicide registrations and meets Nordic Swan ecolabel
0 requirements for slimicide use in printing paper.
FINLAND
(20ppm) (50ppm) (100ppm) (200ppm) Myacide S1 is registered as a paper slimicide.
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FRANCE
Approved for food contact use as a paper slimicide by the
Ministere de la Consommation.
GERMANY
BgVV - Recommendations for food-contact applications.
XIV,2f - substances added to dispersions to prevent microbial
attack.
XXXVI, B V11 - paper and board, slimicides.
NETHERLANDS
Water and paper treatment registration.
SWEDEN
Myacide S1 is registered for use as a paper slimicide.
Myacide AS meets Nordic Swan labelling requirements for
slimicide use in printing paper.
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Protectol GA 50 / Protectol GA 24
Biocide
Protectol GA 50 biocide is a 50% solution of 1,5- M.I.C. data on Protectol GA 50 has been
Pentanedial commonly known as Glutaraldehyde. generated using in-house methodology. It should
It is very effective against a broad spectrum of be noted that due to the influence of media
bacteria and fungi common to the papermaking constituents, the M.I.C. results are generally
industry and is useful in the prevention of slime higher than the effective doses required in-use.
build-up in all areas of the manufacturing process.
Protectol GA 50 has a rapid speed of kill, is cost Test Organism M.I.C. (ppm)
effective and easy to use. In paper processing, Staphylococcus spp. 50
the principal benefit of Protectol GA 50 is that it Bacillus spp. 1250
can be used as a stand-alone product. Desulphovibrio spp. 60
Pseudomonas spp. 150 - 250
QUALITY Candida spp. 1250
Protectol GA 50 is a clear, colourless solution Aspergillus spp. 475
containing an active content of 50%
Glutaraldehyde in water.
USAGE RECOMMENDATIONS
Protectol GA 50 is classed as an aldehyde which is
Solubility, Stability and Compatibility
effective against Gram positive and Gram negative
bacteria and fungi. Protectol GA 50 is soluble in water and a range of
polar organic solvents. This facilitates use in the
Protectol GA 24 is a clear, colourless solution vast majority of water-based systems and ensures
containing an active content of 24% that it can exert maximum effect at the site of
Glutaraldehyde in water. contamination in the paper process. Stability is
reduced above pH7 and at elevated temperatures
Both products have a shelf life of at least six months. (>40C).
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Bulk Pulp
Protectol GA 50 can be used to preserve bulk
pulp and control both foul odours and general
biodeterioration of stock. It may be dosed directly
into the hydropulper, machine chest or stock
chest. A single slug dose of between 100ppm and
500ppm is sufficient to provide control in the
stock. In situations where contamination is high,
repeat dosing every 1 - 7 days may be required.
REGISTRATIONS
Paper Mill Additives
NORTH AMERICA
To inhibit the growth of spoilage bacteria during USA
the manufacture of water-based solutions, EPA - BASFs Glutaraldehyde is approved for use as a paper
suspension concentrates and emulsions, Protectol slimicide.
GA 50 may be dosed at 100-500ppm based on FDA 21, CFR - Code of Federal Regulations. Listings are:
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Protectol DZ / Protectol DZ P
Biocide
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176.180 Components of paper and paperboard in contact with FINLAND
dry food. Products based on Tetrahydro-3,5-dimethyl-2H-1,3,5-
thiadiazine-2-thione are provisionally approved for use as
176.230 Preservative used in paper coatings for use in contact
slimicides in papermaking.
with food.
176.300 Paper slimicide use.
Dazomet is on the chemical register of Japan (MITI), Australia
CANADA
(AICS), Korea and Philippines.
BASFs Dazomet is approved by Health Canada for the
manufacture of formulated products.
EUROPE (EU)
GERMANY
BgVV recommendations for food-contact applications.
XIV, 2f - Substances added to dispersions to prevent microbial
attack.
XXXVI, B VII Paper and board, slimicides.
XXXVI/2, IIG - Paper and board for bakery applications, slimicides.
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Protectol HT
Biocide
REGISTRATIONS
USA
USAGE RECOMMENDATIONS TSCA listed.
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The information submitted in this publication is
based on our current knowledge and experience.
In view of the many factors that may affect
processing and application, this data does not
relieve processors of the responsibility of carrying
out their own tests and experiments; neither do
they imply any legally binding assurance of
certain properties or of suitability for a specific
purpose. It is the responsibility of those to whom
we supply our products to ensure that any
proprietary rights and existing laws and legislation
are observed.
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BASF MicroCheck Limited BASF Aktiengesellschaft BASF AB
Ruddington Fields Business Park, Specialty Chemicals Specialty Chemicals Nordic
Mere Way, Ruddington, Nottingham, D-60551 Frankfurt S-41314 Gteborg
NG11 6JS, England Fax: +49 (0) 69 633 08 121 Fax: +46 (0) 31 639 900
BASF Aktiengesellschaft
BASF Espanola S.A. BASF plc
Specialty Chemicals
Specialty Chemicals Specialty Chemicals
D-67056 Ludwigshafen E-08080 Barcelona Cheadle, Cheshire, SK8 6QG
Fax: +49 (0) 621 60 93 937 Fax: +34 (0) 93 488 30 16 Fax: +44 (0)161 485 5487
BASF Corporation BASF South East Asia PTE Ltd BASF S.A.
3000 Continental Drive-North 7 Temasek Boulevard Specialty Chemicals
~
Mount Olive, NJ 07828-1234 30-01 Suntec Tower One 09851-550 Sao Bernardo do Campo - SP
www.basf.com Singapore 038987 Brazil
For technical service, Fax: +65 (0) 432 36 93 Fax: +55 (0) 11 751 25 43
Myacide and Protectol are registered trademarks