BRAIN INJURY PATIENTS (LITERATUR REVIEW) Heni Maryati* *Lecture of Pemkab Jombang Institute of Health Science Departement of Medical Surgical and Critical Care Nursing Jombang Indonesia Email: zahra.zubir@yahoo.com ABSTRACT Introduction: Intracranial pressure (ICP) can be elevated in traumatic brain injury. Raised ICP is a lift threatening conditions. Unless recognized and treated early to reduce cerebral perfusion pressure (CPP) and progress to brain herniation and death. Management of elevated ICP is, in part, dependent on the underlying cause. The purpose of this literature review was to find a management of a noninvasive physical intervention procedural for decreasing intracranial pressure for brain injury and reduce the duration of treatment invasive. Method: Systematic searches were undertaken using Medline database, PubMed and Cochrane, restricted from 2011 to 2016. There 12 articles included by searching through the appropriate key word topic, but only 5 articles were selected based on the inclusion criteria. Results: Medical options for treating elevated ICP include head of bed elevation, IV mannitol, hypertonic saline, transient hyperventilation, barbiturates. A head elevation of 30 or 45 degrees is optimal for decreasing intracranial pressure. Discussion: Head elevations of 30 or 45 degrees is optimal a conventional nursing of a noninvasive physical intervention procedure for decreasing intracranial pressure for brain injured. Is the most effective management that showed simple, inexpensive treatment procedure and can be applied in variety ages today, independent nursing intervention without side effect. Recommended in clinical practice, intensive care unit staff members need to cautiously perform head elevation of 30 or 45 degrees its physiologic effect and potential hazard.
INTRODUCTION elevated ICP6.. Intracranial pressure (ICP) can
Traumatic brain injury (TBI) and its be elevated in traumatic brain injury. complications are the leading of mortality and Management of elevated ICP is, in morbidity. In the US alone over 2,300 deaths, part, dependent on the underlying cause. 42,000 hospitalizations, and 404,000 Medical options for treating elevated ICP Emergency Department visits occurs annually include head of bed elevation, IV mannitol, among children 0 -14 years old related to TBI. hypertonic saline, transient hyperventilation, Mortality with severe TBI is often the result of barbiturates, and if ICP remains refractory, a refractory increase in intracranial pressure sedation, endotracheal intubation, mechanical (ICP). Therefore prevention and management of ventilation, and neuromuscular paralysis. raised ICP is increasingly recognized as central Surgical options include CSF drainage if to current neuro-critical care. Increased ICP is hydrocephalus is present and decompression of an important caused of secondary brain injury in a surgical lesion, such as an intracranial TBI and both degree and duration of high ICP is hematoma/ large infarct or tumor, if the associated with poor outcomes. Sustained patients condition is deemed salvageable3. The increased to 20 mmHg for >5 min may need purpose of this literature review was to find a treatment. Though the efficacy of treatment method and technique of a noninvasive physical based on ICP monitoring has been questioned intervention procedural for decreasing intracranial pressure (ICP). Increased intracranial pressure for brain injury, reduce the intracranial pressure (ICP) is associated with duration of treatment invasive, and reduce the worse outcome after traumatic brain injury cost of treatment. Head elevation a conventional (TBI). The current guidelines and management nursing procedure for brain injured individuals strategies are aimed at maintaining adequate with intracranial hypertension. It is performed cerebral perfusion pressure and treating with the intent of reducing intracranial pressure (ICP) by means of a noninvasive physical intervention. Head up position may have than at 10 and 15 degrees. Patients with beneficial effect on intracranial pressure (ICP) increased intracranial pressure significantly via changes in mean arterial pressure (MAP), air benefitted from a head elevation of 10, 15, 30 way pressure, central venous pressure and and 45 degrees compared with 0 degrees. A cerebral spinal fluid displacement. However, in head elevation of 30 or 45 degrees is optimal for some circumstances head up position may decreasing intracranial pressure4. According to decrease MAP with in turn will result in a research Agbeko RS, et al (2012) that in severe paradoxical rise in ICP trough auto regulation pediatric traumatic brain injury, the relations the degree of head elevation has to be titrated by ship between change in head of the bead and evaluating the most adequate cerebral perfusion change in intracranial pressure was negative and pressure (CPP) for each patient by means of linier. The lowest intracranial pressure was trans cranial. A change in head position can lead usually, but not always, achieved at highest to a change in intracranial pressure, however, head 0f the bed angles depend, in parts, on the there a conflicting data regarding the optimal subjects height. degree of elevation that decreases intracranial The other therapies to reduce elevated pressure in post craniotomy patients. Patients intracranial pressure if ICP not remains with increased intracranial pressure refractory used osmotic agents, such as significantly benefitted from a head elevation of mannitol, hypertonic saline and the other 10, 15,30 and 45 degrees compared with 0 therapies, such as hyperventilation and degrees. A head elevation of 30 or 45 degrees is barbiturates. Recording the research Scalfani, et optimal for decreasing intracranial pressure. al (2012) that in cerebral blood flow (CBF) is Recommended in clinical practice, intensive reduce after severe traumatic brain injury (TBI) care unit staff members need to cautiously with considerable regional variation osmotic perform head elevation of 30 - 45 degrees with agents are used to reduce elevated intracranial a thorough understanding of its physiologic pressure (ICP). In 8 patients with acute TBI, we effect and potential hazard4. measured regional CBF with positron emission tomography before and 1 hour after METHOD administration of equi osmolar 20% mannitol (1 A literature review revealed that ml/kg) or 23,4 % hypertonic saline (0,686 studies have been conducted in a range of ml/kg) in regions with focal injury and baseline countries by using a variety of management to hypo perfusion CBF < 25 ml per 100 gr/min. screen leaners decrease intracranial pressure for Result that osmotic therapy reduce the number traumatic brain injury patients. It was of hypo-perfuse brain regions by 40% (p , conventional nursing of a noninvasive physical 0,001) 5. Recording the research Mangat HS intervention procedure for decreasing (2012) that in hyperosmolar agents are intracranial pressure for brain injured reduce the commonly used as an initial treatment for the duration of treatment invasive, and reduce the management of raised intracranial pressure cost of treatment. (ICP) after several traumatic brain injury (TBI). A head elevation of 30 or 45 degrees They have an excellent adverse effect profile is optimal for decreasing intracranial pressure. compared to other therapies, such as Is the most effective management that showed hyperventilation and barbiturates, which carry simple, inexpensive treatment procedure and the risk of reducing cerebral perfusion. can be applied in variety ages today, The hyperosmolar agent mannitol has independent nursing intervention without side been used for several decades to reduce raised effect. It was conventional nursing of a ICP, and there is accumulating evidence from noninvasive physical intervention procedure for pilot studies suggesting beneficial effects of decreasing intracranial pressure for brain hypertonic saline (HTS) for similar purposes. In injured. According to research J. Adv Nurs ideal therapeutic agent for ICP reduction should (2015) that a changes in head position can lead reduce ICP while maintaining cerebral to a change intracranial pressure. Compared perfusion (pressure). While mannitol can cause with a degree 10,15,30 and 45 degrees of head dehydration over time, HTS helps maintain elevation resulted in lower intracranial pressure. normovolemia and cerebral perfusion, a finding Intracranial pressure at 30 degrees was not that has led to a large amount of pilot data being significantly different in comparison to 45 published o benefits of HTS, albeit in small degrees of head elevation and was lower that cohorts. Prophylactic therapy is not recommended with mannitol, although it may 45 degrees is optimal for decreasing be beneficial with HTS. To date, no large intracranial pressure. Is the most effective clinical trial has been performed to directly management that showed simple, inexpensive compare the two agents. The best current treatment procedure and can be applied in evidence suggest that mannitol is effective in variety ages today, independent nursing reducing ICP in the management of traumatic intervention without side effect. It was intracranial hypertension and carries mortality conventional nursing of a noninvasive physical benefit compared to barbiturates. Current intervention procedure for decreasing evidence regarding the use of HTS in severe intracranial pressure for brain injured. TBI is limited to smaller studies, which a benefit The other therapies to reduce elevated in ICP reduction and perhaps mortality7. intracranial pressure used osmotic agents, such According to research Mangat HS,et al (2015) as mannitol, hypertonic saline and the other that a Hypertonic saline (HTS) given as bolus therapies, such as hyperventilation and therapy was more effective than mannitol in barbiturates. Mannitol can cause dehydration lowering the cumulative and daily ICP burdens over time, HTS helps maintain normovolemia after severe TBI. Patients in the HTS group had and cerebral perfusion. Prophylactic therapy is significantly lower number of ICU days. not recommended with mannitol, although it may be beneficial with HTS. To date, no large RESULTS clinical trial has been performed to directly Systematic searches were undertaken compare the two agents. The best current using Medline database, Pubmed and Cochrane evidence suggest that mannitol is effective in , restricted from 2011 to 2016. There 7 articles reducing ICP in the management of traumatic included by searching through the appropriate intracranial hypertension and carries mortality key word topic, but only 3 articles were benefit compared to barbiturates. selected based on the inclusion criteria. Management of raised ICP includes care air CONCLUSION AND way, ventilation and oxygenation, adequate RECOMMENDATION sedation and analgesia, neutral neck position, Head elevations of 30 or 45 degrees is head end elevation 30 or 45 degrees and short optimal a conventional nursing of a noninvasive term hyperventilation, and hyperosmolar physical intervention procedure for decreasing therapy (manitol or hypertonic saline) , in intracranial pressure for brain injured. Is the critically raised ICP barbitural coma, moderate most effective management that showed simple, hypothermia and surgical decompression. inexpensive treatment procedure and can be applied in variety ages today, independent DISCUSSION nursing intervention without side effect. Intracranial pressure (ICP) can be In clinical practice, intensive care unit elevated in traumatic brain injury. Management staff members need to cautiously perform head of elevated ICP is, in part, dependent on the elevation of 30 or 45 degrees its physiologic underlying cause. Medical options for treating effect and potential hazard. elevated ICP include head of bed elevation, IV mannitol, hypertonic saline, transient REFERENCES hyperventilation, barbiturates, and if ICP Agbeho RS, et al. (2012). Intracranial pressure remains refractory, sedation, endotracheal and cerebral perfusion pressure responses intubation, mechanical ventilation, and to head elevation change in pediatric neuromuscular paralysis. 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