VIII.

DRUG STUDY

DRUG ORDER
(generic
name, brand MECHANISM OF INDICATION CONTRAINDIATION ADVERSE EFFECTS NURSING RESPONSIBILITIES
name, ACTION
classification,
frequency,
route,)

Generic name: Binds to beta2- Treatment for Contraindicated to CNS: nervousness, 1. Chest tapping after inhalation.
Albuterol adrenergic bronchospasms hypersensitivity of restlessness
receptors in albuterol 2. Do not exceed recommended
Brand name: airway smooth CV: chest pain, dosage.
Comvibent muscle, leading to palpitations,
activation of 3. Administer pressurized
Classification: adenylcyclase and GI: nausea and inhalation drugs forms during
Bronchodilators increased levels of vomiting. second half of inhalation
cyclic. because the airways are open
Dosage: wider lead to albuterol
1 neb distribution is more extensive.

Route: 4. Use minimal doses for minimal

Inhalation periods drug tolerance may
occur if prolonged use.
Frequency:
q4

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 VIII. DRUG STUDY

DRUG ORDER
(generic
name, brand MECHANISM OF INDICATION CONTRAINDIATION ADVERSE EFFECTS NURSING RESPONSIBILITIES
name, ACTION
classification,
frequency,
route,)

Generic name: Blocks the GERD- treatment Contraindicated with CNS: headache, 1. Obtain baseline of liver function
Esomeprazole formation step of of heartburn and allergy to nexium. dizziness test and monitored periodically
magnesium acid production. other related dosage therapy.
symptoms. GI: diarrhea, 2. Maintain supportive treatment
Brand name: abdominal pain, as appropriate for underlying
Nexium nausea, and vomiting. problem

Classification: Respiratory: 3. Provide additional comfort

Proton pump URI symptoms measure to alleviate discomfort
inhibitor from GI effects and headache.

Route: 4. Arrange regular medical folo-up

IVTT visits when taking this rug.

Dosage:
40mg

Frequency:
Q12

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 VIII. DRUG STUDY

DRUG ORDER
(generic
name, brand MECHANISM OF INDICATION CONTRAINDIATION ADVERSE EFFECTS NURSING RESPONSIBILITIES
name, ACTION
classification,
frequency,
route,)

Generic name: Reduces fever by Analgesic- Contrainicated with CV: myocardial 1. Do not exceed at
Paracetamol acting directly on antipyretic in allergy to naprex damage recommended dosage.
the hypothalamus patient with
Brand name: heat regulating bleeding diatheses CNS: headache 2. Avoid using multiple
Naprex center to and upper GI preparations containing
causevasodilation disorder GI: hepatic toxicity acetaminophen.
Classification: and sweating and failure.
Analgesia which helps 3. Give drug with food if GI upset
dissipate heat.. occurs.
Route:
IVTT 4. Discontinue if hypersensitivity
occurs
Dosage:
300mg

Frequency:
Q4

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 VIII. DRUG STUDY

DRUG ORDER
(generic
name, brand MECHANISM OF INDICATION CONTRAINDIATION ADVERSE EFFECTS NURSING RESPONSIBILITIES
name, ACTION
classification,
frequency,
route,)

Generic name: Stimulates To correct Contraindicated in CNS: headache 1. Use cautiously in patient with
Dopamine dopaminrgic and hypotension thus, patients with CV: ectopic beats, occlusive vascular disease, cold
hydrochloride alpha and beta improving tissue uncorrected tachycardia, angina, injuries, diabetic endarteritis and
receptors of the perfusion tachyarrythmias, palpitations, arterial embolism.
Brand name: sympathetic pheochromocytoma, hypotension, 2. During infusion, frequently monitor
intropin nervous system. or ventricular GI: nausea, vomiting ECG, blood pressure, cardiac
Action is dose- fibrillation. GU: elevated urinary output, central venous pressure,
Classification: related; large catecholamine levels. pulmonary artery wedge pressure,
symphatomime doses cause Metabolic: azotemia, pulse rate, urine output, and color
tics mainly alpha hyperglycemia and temperature of limbs.
stimulation. Respiratory: dyspnea, 3. Check urine output often. If urine
Route: asthmatic episodes. flow decreases without
IV Skin: necrosis and hypotension, notify physician
tissue sloughing with because dosage may need to b
Dosage: extravasation, reduced
14cc/hr piloerection 4. After drug is discontinued, watch
Other: anaphylactioc closely for sudden decrease in
Frequency: reactions. blood pressure. Taper dosage
Q1 slowly to evaluate stability of blood
pressure
5. Instruct client that report any signs
of discomfort at the insertion site.

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 VIII. DRUG STUDY

DRUG ORDER
(generic
name, brand MECHANISM OF INDICATION CONTRAINDIATION ADVERSE EFFECTS NURSING RESPONSIBILITIES
name, ACTION
classification,
frequency,
route,)
Generic name:
Zolendronic Action leads to Treatment for Contraindicated with CV: hypotension Make sure that patient is well hydrated
acid decrease in the myelomas and allergy to zometa before use; vigorous saline hydration
release of calcium documented bone GI: nausea and to establish a urine output of about
Brand name: from bone and a metastases from vomiting 2L/day is suggested.
Zometa decrease in serum solid tumors in
calcium. conjunction with Respi.: dyspnea Monitor urinary output and assess
Classification: standard patient for hydration status continually.
Calcium antineoplastic
regulator therapy. Ensure that drug infuses are not less
than 15min.
Route:
Via vial Provide small meal if GIO upset
occurs
Dosage:
200ml Assess for nutritional consult if nausea
and vomiting persist.

Frequency:
OD

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 VIII. DRUG STUDY

DRUG ORDER
(generic
name, brand MECHANISM OF INDICATION CONTRAINDIATION ADVERSE EFFECTS NURSING RESPONSIBILITIES
name, ACTION
classification,
frequency,
route,)

Generic name: Increase serum Hypocalcemic Hypersensitivity to CNS: headache 1. Instruct patient to consume milk
calcium level through emergency drug and dairy products during
gluconate direct effects on GI: nausea and therapy
bone. vomiting
Decrease 2. Refer patient to dietitian for
Brand name: osteoclastic by help in meal planning and
Cal-lac reduces mineral preparation.
release and
Classification: collagen 3. Review all other significant and
Elecrolyte breakdown in life threatening adverse
replacement bones. reaction and interaction.
agent

Route:
Via vial

Frequency:
OD

Dosage:
10% solution

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 VIII. DRUG STUDY

DRUG ORDER
(generic
name, brand MECHANISM OF INDICATION CONTRAINDIATION ADVERSE EFFECTS NURSING RESPONSIBILITIES
name, ACTION
classification,
frequency,
route,)

Generic name: .Interferes with Severe infection Hypersensitivity to CNS: seizures 1. Monitor neurologic status
cefuroxime bacterial cell wall include bone drugs. particularly sign of impending
synthesis and infection GI: nausea and seizures.
Brand name: division by binding vomiting
Zegen to all cell wall 2. Monitor kidney and liver
causing cell to die. Hematologic disorder: function.
Classification: hemolytic anemia.
anti infective 3. Advise the patient to report
CNC changes.
Dosage:
750mg 4. Advise patient to immediately
report rash or bleeding
Route: tendencies.
PO

Frequency:
Q8

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 VIII. DRUG STUDY

DRUG ORDER
(generic
name, brand MECHANISM OF INDICATION CONTRAINDIATION ADVERSE EFFECTS NURSING RESPONSIBILITIES
name, ACTION
classification,
frequency,
route,)

Generic name: Antagonizes the Treatment of Contraindicated with Hot flushes, breat 1. Monitor liver function test
Bicalutamide effects of advanced allergy to tenderness, nausea
androgen and prostatic bicalutamide and its and vomiting, dry skin, 2. Administer LH_RH analogue.
Brand name: cellular level by carcinoma in component. jaundice, anorexia,
Casodex binding to combination with dry mouth. 3. Tell the patient that any drug
androgen receptor LH-RH analogue related to hair loss should
Classification: on target bone report immediately.
Antiandrogen
4. As appropriate, review all other
Dosage: significant and life threatening
50mg adverse reaction and
intervention especially related
Route: to the drugs and test
Po

Frequency:
OD

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 VIII. DRUG STUDY

DRUG ORDER
(generic
name, brand MECHANISM OF INDICATION CONTRAINDIATION ADVERSE EFFECTS NURSING RESPONSIBILITIES
name, ACTION
classification,
frequency,
route,)

Generic name: Bactericidal: Treatment for intra Contraindicated with CNS: headache 1. Report if some adverse effects
Sulperazone inhibits synthesis abdominal allergy to may worsens
of bacterial cell infection sulperazone GI: nausea and
Brand name: wall causing cell vomiting 2. Discontinue drug if
Cefobid death. hypersensitivity occurs.
GU: nephrotoxicity
Classification:
antibiotic

Route:
oral

Dosage:
250mg

Frequency:
Q12

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 VIII. DRUG STUDY

DRUG ORDER
(generic
name, brand MECHANISM OF INDICATION CONTRAINDIATION ADVERSE EFFECTS NURSING RESPONSIBILITIES
name, ACTION
classification,
frequency,
route,)

Generic name: Forms a reversible Treatment for Contraindicated with GI: nausea and 1. Report if some adverse effects
Tranexemic bleeding (lower hypersensitivity to vomiting, anorexia may worsens
complex that
acid gastrointestinal hemostan and its also.
displaces bleeding). component 2. Discontinue drug if
Brand name: CNS: headache may hypersensitivity occurs.
plasminogen from
Hemostan occur
fibrin resulting in
Classification:
inhibition of
Anti
hemorrhagic fibrinolysis; it also
inhibits the
Route: IVTT
proteolytic activity
Dosage:
of plasmin
500g

Frequency:ev
ery 6 hours

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VIII. DRUG STUDY

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