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Annotated Bibliography Graphic Organizer

Copy and paste to your own document to complete this chart to turn in (Sample below)
Name:

Works Cited
Source #____ Bibliography Fricker, Rosemary A., et al. "Transplanting Intact Donor Tissue
(MLA or APA) Enhances Dopamine Cell Survival and the Predictability of Motor
Improvements in a Rat Model of Parkinson's Disease." Plos ONE, vol.
10 pts 7, no. 10, Oct. 2012, pp. 1-8. EBSCOhost,
doi:10.1371/journal.pone.0047169.

The present study illustrates the potential importance of maintaining


Annotation: the integrity of VM donor tissue during its reparation for, and
(Describe ALL info. that implantation into, animal models of Parkinson’s disease (PD).
might be important for your Maintaining tissue integrity throughout implantation procedures offered
paper. Explain to the the possibility to increase the number of donor dopamine neurons
reader and/or summarize surviving transplantation and proved to be a better predictor of graft
what might be found in this function based on dopamine cell content. Overall, the study has
source) allowed them to use less mature tissue on rats that have Parkinson’s
disease to see if it shows and improvement. There are a lot of room to
35 pts improve but because it is still in testing state there is no true results to
the trials.

“The current use of such a large number of precisely aged donors is


Potential Quotes: due mainly to the fact that a vast number of donor neurons are
(Are there any significant destroyed during the preparation of cell suspensions for trans-
quotes you can use or plantation.”
paraphrase from this
source?) “At 2 and 4 weeks following 6-OHDA lesioning all animals in the study
displayed an ipsilateral (to the lesion) rotation bias after d-
15 pts amphetamine administration.”

This source is credible because the study was done in Keele


Assessment: University and also they are able to show there studies and they have
(Analyze and explain why permits for working on animals. Another reason it is credible is
this source is credible) because all of the work has been credited if they used outside sources.

15 pts

I plan to combine this work and other work from other people to see if
Reflection: the results are consistent with each other. To come to a conclusion if
(How will you potentially using transplant cells to help Parkinson’s disease. Because I will not be
use it?) able to conduct my own research I will have to rely on other peoples
works to come to a conclusion.
25 pts

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