Dr Desi RM #51101

SIP:......
JlJepun, 9, Denpasar Bali

Telp: 255-123
Denpasar, 2 Mei 2017

R/
Acetaminophen 0.650
Codeine hydrochloride 0.010

M.fla. pulvvdtd caps No XX

Sig: i q4-6h prn pain

Nama:vDani (20 TAHUN)

Alamat: Jl Raya HayamWuruk 72,Denpasar Telp: 254-124

Dr Rosita
SIP………….
Jl. Kecubung 20, Denpasar
Phone: 555-1234

Tabanan, 23 Mei 2016

R/ Hydrocortisone cream 1%
Sig: apply to face b.i.d. after cleansing

Nama : Lyoni
Alamat: JlKamboja No. 8, Denpasar Telp: 555-5678

Ne iteratur

1. Analyze the prescription based on good prescribing concept

2. Describe the problem, therapeutic objective, prescribing information, instruction, and warning
to the patient, and how the patients do monitoring the outcome therapy by her-self.
3. How many mg of acetaminophen for every 6 hours?
4. How many mg of codeine phosphate will be dispensed for that formula?
5. Rewrite your prescription properly
Scenario 1: There are several cardswhich describe clinical cases and or symptom of diseases
which is chosen at introduction session (see Appendix 7). Each group consist of minimal 10
students must develop P-treatment and P-drug completely with description and type in the
form P-treatment and P-drug enclosed in this study guide (Appendix 6). The students have to
prepare this assignment together out of class while presenting this individually in the class.

Card 1.Arman, 50 y.o suffered from chronic cough, and he come to primary health center
in the afternoon as he got fever since in the morning. He felt uncomfortable every night, he
got cough and he could not sleep well. He was a heavy smoker. There is no information
about his disorder also a specific physical examination about his inflammation on his throat.
The doctor asked him to stop smoking and prescribed three medications: Codein 15 mg
Tablet, Dextromethorphan 15 mg tablet, Ambroxol 30mg tablet, but he thought he just
prescribed just one of threefor short term 3days, 3 times daily. Write a prescription for this
patient on the templateprescription provided.
APPENDIX 6

FORM P-DRUG
1. Diagnosis: batuk kronis

2. Define objective of therapy: batuk

3. Inventory of Effective Group of Drugs:

GROUP Efficacy Safety Suitability Cost

(PK/PD) (SE/ADR) (CI)
Narkotika (codein) PK : ADR : akan CI : susah
Ab : diabsorpsi sangat menyebabkan bernapas,
baik dalam saluran ketergantungan, kerusakan
pencernaan. Waktu mual dan jalur napas,
untuk mencapai muntah, asma akut
konsentrasi plasma konstipasi, dan kronik
tertinggi adalah 1-1,5 bingung,
jam kesulitan
Dis : dapat menyebar berkemih,
melewati plasenta dan mulut kering
dapat masuk ke dalam
ASI. Ikatan protein
plasma mencapai 7-
25% serta volume
distribusi mencapai 3-
6 L/kg
Met : oleh hati dengan
cara dimetilasi oleh
ikatan oksigen dan
nitrogen untuk morfin,
nor codein dan
metabolit lainnya
 termasuk normorfin
dan hidrocodon
Eks : melalui urin,
khususnya konjugat
dengan asam
glukoronik. Waktu
paruh plasma sekitar
3-4 jam.
Antitusiv PK : ADR : sangat CI : pasien
(Dextromethorphan) Ab : diabsorpsi sangat jarang dalam risiko
baik dalam saluran ditemukan kegagalan
pencernaan. Waktu namun dapat pernapasan.
untuk mencapai terjadi pusing,
konsentrasi plasma gangguan pada
tertinggi adalah 2-3 saluran
jam pencernaan,
Dis : distribusi secara lemes
luas
Met : terjadi di dalam
hati melalui demetilasi
oleh enzim CYP2D6
untuk dekstrorpan.
Mengalami first pass
metabolism
Eks : melalui urin,
khususnya konjugat
dengan asam
glukoronik. Waktu
paruh plasma sekitar
2-4 jam dan 24 jam
ketika
Ekspektoran PK : SI : reaksi CI :
(ambroxol) intoleran Hipersensitif
pernah terhadap
dilaporkan ambroxol
tetapi jarang
terjadi. Efek
samping yang
ringan pada
saluran
pencernaan
pernah
dilaporkan
rekasi alerg,
demam.

4. GROUP CHOICES [mark (+/-)]

 5. CHOOSE P-DRUG[mark (+/-)]

CHOICES OF P-DRUG Efficacy Safety Suitability Cost

(PK/PD) (SE/ADR) (CI)

Active substance, dosage form:

Dosage schedule:
Duration:

6. COUNSEL THE PATIENT

----------------------------------------------------------------------------------------------------------------
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Card 2.A mother and his 4years old boy (Tony) come to primary health care. Her boy
complained fever, temperature axial 39.50C since in the morning and cough. The doctor
consider that he suffered pneumonia infection, after physical examination he considers to
prescribe Tetracycline capsule 250mg, every 8 hours, for 7 days, but he confused to adverse
drug reaction. Give a suggestion for treatment.

FORM P-DRUG
1. Diagnosis: infeksi

2. Define objective of therapy:

3. Inventory of Effective Group of Drugs:

GROUP Efficacy Safety Suitability Cost

(PK/PD) (SE/ADR) (CI)
Tetracyclin PK : ADR : angka CI :
Ab : kejadian tidak hipersensitif
Dis : diketahui. terhadap
Met : Pada tetrasiklin
Eks : kardiovaskular atau terhadap
: perikarditis komposisi
formulasi
 SSP : yang terdapat
meningkatnya dalam obat.
tekanan Jangan
kranial diberikan
Psidotumor kepada anak
cerebri dibawah 8
Dermatologi : tahun dan
fotosenditifiti wanita hamil
Endokrin :
sindrome DI
4. GROUP CHOICES [mark (+/-)]

5. CHOOSE P-DRUG[mark (+/-)]

CHOICES OF P-DRUG Efficacy Safety Suitability Cost

(PK/PD) (SE/ADR) (CI)

Active substance, dosage form:

Dosage schedule:
Duration:

6. COUNSEL THE PATIENT

Card 3.Reny 20 y.o. came to GP for her rash and itchy on his leg and neck. She told that she
ate seafood at her lunch 2 hours ago. She got food allergy before but she wanted to try just
small seafood at a moment. What is your solution for her if the GP prescribes oral tablet and
topical preparations. The following are her potential drugs to choose from: Dipenhydramine 25
mg tablet; Salicilate acid Talcum; Hydrocortisone Cream 1%. Write a prescription for this
patient on the templateprescription provided.

FORM P-DRUG
1. Diagnosis: infeksi

2. Define objective of therapy:

3. Inventory of Effective Group of Drugs:

 4. GROUP CHOICES [mark (+/-)]

GROUP Efficacy Safety Suitability Cost

(PK/PD) (SE/ADR) (CI)
Dipenhydramin PK : ADR : angka CI :
Ab : kejadian tidak hipersensitif
Dis : diketahui. terhadap
Met : Pada tetrasiklin
Eks : kardiovaskular atau terhadap
: perikarditis komposisi
SSP : formulasi
meningkatnya yang terdapat
tekanan dalam obat.
kranial Jangan
Psidotumor diberikan
cerebri kepada anak
Dermatologi : dibawah 8
fotosenditifiti tahun dan
Endokrin : wanita hamil
sindrome DI

5. CHOOSE P-DRUG[mark (+/-)]

CHOICES OF P-DRUG Efficacy Safety Suitability Cost

(PK/PD) (SE/ADR) (CI)

Active substance, dosage form:

Dosage schedule:
Duration:

6. COUNSEL THE PATIENT

Scenario 2: The are several prescription and clinical case or symptom card which are going
to share to students and must assess 1 prescription and 1 case per group. First, for the
prescription, the student must analyzed the prescription based on prescribing rule’s and
medication safety concept and rewrite the good prescription in prescription form enclosed.
Second, for the clinical case and or symptom card, the student must calculate the dose
properly and write a good prescribing based on the patient’s need.