Polyuria

POLYURIA

Common causes:
diabetes mellitus, diabetes insipidus,
medication, hyperparathyroidism,
renal disease

Yes No
Med causes?

Diuretics Check labs: glucose, urinalysis,

Caffeine calcium, BUN, creatinine.
Alcohol
Lithium

Elevated Normal
glucose glucose
Address
meds.
Diabetes Urinalysis
mellitus

Pyuria, nitrates +, Normal urinalysis

leukocyte esterase +

Obtain
UTI serum calcium,
TSH, BUN,
creatinine.

Calcium elevated Calcium normal

Hyperparathyroidism Renal function

Malignancy

Elevated Normal renal

BUN/creatinine function

Renal disease Low TSH Low urine osmolality,

low specific gravity

Hyperthyroidism Yes No

Diabetes Refer and consider

insipidus psychiatric cause.

Dennis Smith, DO and James L. Taylor, PharmD

Jakes AD, Bhandari S. Investigating polyuria. BMJ. 2013;347:f6772.

Copyright © 2015 Wolters Kluwer Health, Inc. Unauthorized reproduction of the article is prohibited.

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