Drug name Drug class Therapeutic Indications Contraindications Adverse effects Teaching points

actions and cautions

Gentamycin Aminoglycoside Bactericidal: Parenteral -contraindicated with -seizures, -apply ophthalmic
Inhibits protein Intrathecal allergy to any neuromuscular preparations by tilting
synthesis in Ophthalmic aminoglycosides blockade, head place; place
susceptible Topical -use cautiously with ototoxicity, tinnitus, medications into
grains of gram renal or hepatic dizziness, cinjunctival sac and
negative failure, pre-existing agranulocytosis, close eye. Cleanse
bacteria; hearing loss, infant pancytopenia, area before applying
appears to botulism, burn purpura, rash, pain, -you may experience
disrupt patients irritation, nausea, these side effects:
functional vomiting, apnea, ringing in the ears,
integrity of photosensitization headache, dizziness,
bacterial cell nausea, vomiting,
membrane, burning, blurring of
causing cell vision.
death. -report pain at injection
site, severe headache,
dizziness, loss of
hearing, changes in
urine output,
worsening of the
condition, rashes,
irritation
Metronidazole Antibiotic Bactericidal: -acute infection -contraindicated with Headache, -take full course of
Antibacterial Inhibits DNA with anaerobic hypersensitivity to dizziness, ataxia, drug therapy. Take the
Amebecide synthesis in bacteria metronidazole unpleasant metallic drug with food
Antiprotozoal specific -acute intestinal -use cautiously with taste, anorexia, -do not drink alcohol
anaerobes, amebiasis CNS diseases, vomiting, diarrhea, -your urine may be
causing cell -amebic liver hepatic diseases,, darkening of the darker in color than
death; anti- abscess candidiasis, blood urine, redness, usual
protozoal- -Trichomoniasis dyscrasias burning, dryness, -apply the topical
trichomonacidal, -topical skin irritation preparation by
amebecidal application cleansing the area.
-prophylaxis for Avoid contact with the
patients eyes.
undergoing - you may experience
colorectal these side effects: dry
surgery mouth with strange
metallic taste (frequent
 mouth care) nausea,
vomiting, diarrhea
-report severe GI
upset, dizziness,
unusual fatigue or
weakness, fever, chills
Nubain Opioid agonist- Acts as an -relief of - contraindicated -sedation, -you may experience
(Nalbuphine antagonist agonist at moderate to with hypersensitivity clamminess, these side effects:
hydroxide) analgesic specific opioid severe pain to nalbuphine, sweating, dizziness, sedation,
receptors in the -preoperative sulphites headache, drowsiness, impaired
CNS to produce analgesia, as a - use cautiously with dizziness, vertigo, visual acuity, nausea,
analgesia and supplement to bronchial asthma, dry mouth, urinary loss of appetite (lying
sedation but surgical COPD, respiratory urgency quietly, eat frequent
also acts to anesthesia depression, anoxia, small feedings)
cause increased ICP, -report severe signs
hallucinations acute MI, such as: severe
and is an nausea, dizziness,
antagonist in mu difficulty in breathing
receptors