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PICOT Paper
Diana VanRhee
Abstract
This paper encompasses nursing knowledge that was used in a PICOT question which
was researched through health data bases. The PICOT question explores whether using pre-
operative versed (midazolam) in pediatric patients provides better post-operative pain control
than not using versed (midazolam). The methodology, levels of evidence and a review of the
research literature is produced in detail. Using the results of the research, the significance to
nursing and future research are demonstrated and suggestions for changing current practices are
noted.
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Introduction
Nursing care is directed by Evidence Based Practice (EBP) which in turn is founded on
evidence based research. When new data is produced from research it must clearly be
communicated within the healthcare setting. Nursing and related personnel must collaborate
efficiently in supporting the EBP and incorporating it in their everyday practice. “The purpose of
this assignment is to reflect how nursing knowledge is disseminated for use in personal and
professional practice” (Ursuy, 2014). This paper explores whether using preoperative versed
(midazolam) in pediatric patients provides better post-operative pain control than not using
versed (midazolam).
Clinical Question
Working in the Surgery, Prep and Recovery Unit of a local hospital, I encounter pediatric
patients that are having surgical procedures. Children under the age of 10 years old have their IV
started in the operating room under general anesthesia, while children over the age of 10 years
old have their IV started in the preoperative area. Both categories of children could be given oral
midazolam preoperatively, however, due to limited IV access, IV midazolam is not given, only
oral midazolam. The anesthesiologist is the one who evaluates the children and orders the
midazolam, however there is no set policy or protocol for that. I began to notice inconsistencies
of the children being medicated with midazolam prior to surgery and it appeared the children
who were medicated with midazolam preoperatively had better post-operative pain control.
When questions arise for discussion or research, the acronym PICOT is a common way to
format the question. P stands for the population/patient, I stands for the area of
interest/intervention, C stands for the comparison/current practice, O stands for the desired
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outcome and T denotes the time frame (Niewswiadomy, 2012, p. 282). The PICOT question
being explored in this paper is “Does medicating with oral versed (midazolam) preoperatively
reduce post-operative pain compared to patients who do not receive preoperative versed
operative pain management and T is during the post-operative period. It is believed the quality
and safety of the pediatric population undergoing surgical procedures would be improved if there
were consistent preoperative medication policies and procedures in place. Post-operative pain
could be improved, thus patient and parent satisfaction could also potentially increase.
Methodology
When researching the PICOT question at hand, I utilized three databases relevant to the
nursing/medical field, which were Cinahl, Cochrane Reviews and Pub-Med. In each database, I
would use the advance search when possible and included key words or phrases. At first, using
the word versed did not reveal many articles, but upon advancing the search to include
midazolam and adding parenthesis around the key words provided more options. So, the search
preoperative pain).
The selection process was further narrowed down after reading the abstracts of numerous
articles. The abstracts provided me with valuable information that easily allowed me to either
include or exclude the article. I tried to include articles that were current, 12 years ago to present.
Levels of evidence is a way to categorize articles based on types of trials, studies, and
expert opinions by using a numerical hierarchy. Each article reviewed was assigned a level of
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evidence using the following level of evidence chart, one being the highest level and seven being
Levels of Evidence
Choosing the levels of evidence to assign to the chosen articles was not an easy process
and the articles chosen for the PICOT question were not done so based only on the level of
evidence given to them. Nursing articles were favored along with the content relevant to the
their scope of practice (White & O’Sullivan, 2012, p. 194). Nurses often shy away from research
and quality related utilization because change is often difficult and why change something that is
working just fine? At the registered nurse level, an RN should evaluate evidence in deciding the
level of care and interventions for the patient outcomes (White & O’Sullivan, 2012, p. 194).
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Discussion of Literature
Article One
The first article reviewed is called “Premedicating children for painful invasive
survey/questionnaire for her research questions and there were 108 participants. The participants
were broken down to include 55 physicians and 53 nurses. The physicians were pediatric
professors and staff oncologists while the nurses involved were clinical nurses or clinical nurse
specialists (Klein, 1992, p. 172). Questions included on the questionnaire reflected current
premedicating practices in their pediatric clients and then they were asked about the patients post
procedure pain using the Likert Scale of 1 to 5 (1 being no pain and 5 being excruciating pain)
(Klein, 1992).
Several drug combinations were used along with oral and intravenous midazolam in
punctures. Although the article is only an evidence level of six (Melnyk & Fineout-Overholt,
2011), the results are significant and can be useful to pediatric nurses. The results revealed that
there was a significant reduction of pain if a pediatric patient was medicated prior to a painful
procedure with agents such as midazolam. Further implications for nursing are standardizing
premeditation care and practices for pediatrics undergoing painful procedures (Klein, 1992, p.
177).
Article Two
The second article, “Pre-anesthetic medication with intranasal dexmedetomidine and oral
midazolam as an anxiolytic. A clinical trial” (Linares et al., 2014) is a comparison trial between
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two medications for preoperative anxiety. This trial was a prospective, randomized, double-
blind, controlled trial that was conducted on children 2-12 years of age (Linares et al., 2014).
There were 108 pediatric patients in the trial and their anxiety was assessed using a modified
Yale scale. Anxiety is closely related to pain and pain perception with children.
Evidence level is a four (Melnyk & Fineout-Overholt, 2011) and the trial was done in
2013, so I chose to include the article based that the information was relevant to the PICOT
question. Although the findings were suggestive of the dexmedetomidine being superior to the
midazolam in reducing anxiety, which could also reduce the pain perception for the children, the
findings were significant and supportive to the issue that pediatric patients could have better post
procedure pain if they were medicated preoperatively. Further research and studies need to be
Article Three
The last article to be discussed is by Fazi et al., “A comparison of oral clonidine and oral
midazolam as preanesthetic medications in the pediatric tonsillectomy patient.” This trial was
randomized and controlled and was a comparative study (Fazi, Jantzen, Rose, Kurth, & Watcha,
2001). It is located in The Cochrane Central Register of Controlled Trials. The study participants
were the ages of 4-12 years old and all were medicated prior to anesthesia with either the
midazolam or clonidine.
Evidence level was rated as a two (Melnyk & Fineout-Overholt, 2011), but the results
were significant to the PICOT question and nursing in comparing the preanesthetic sedation and
post-operative recovery. The children in the midazolam group required less postoperative
analgesia and thus midazolam was considered superior to clonidine as an oral preanesthetic
medication (Fazi et al., 2001). Although this trial was limited to patients receiving
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tonsillectomies, it is indicative of the need for future research on standardizing care practices on
Significance to Nursing
(EBP) and thus nursing practice could potentially be changed to increase the safety and efficacy
of care. “Interprofessional collaboration will make the research stronger and will increase the
likelihood that a satisfactory practice change can eventually be implemented” (White &
O’Sullivan, 2012, p. 137). In today’s nursing practice, nurses have the “capabilities to address a
wide variety of health issues” (Black, 2014, p. 114), however, nurses must act within their Scope
of Practice as defined by the American Nurses Association and outline by The Code of Ethics for
Nurses and the Standards of Nursing Practice (White & O’Sullivan, 2012). That is why it is
Quality and Safety Education for Nurses (QSEN) emphasizes providing quality nursing
education to nursing students and that quality is the responsibility of all individuals in healthcare
(White & O’Sullivan, 2012). QSEN targets the knowledge, skills and attitude for nurses and
incorporates six core competencies. These six competencies are Patient-Centered Care,
Teamwork and Collaboration, Evidence Based Practice, Quality Improvement, Safety and
Informatics (Quality and Safety Education for Nurses, 2013). With the inquiry of this PICOT
question, patient-centered care, evidence based practice, quality improvement and safety were all
explored and utilized. I have gained knowledge and insight to information that is not only
significant to my own nursing practice, but that could potentially impact others.
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Conclusion
The PICOT question explored had supportive and non-supportive data revealed. Material
was overwhelming supportive of pediatric patients being medicated prior to painful procedures
or surgery. Reducing anxiety and pain preoperatively and postoperatively is imperative for the
healing process and patient satisfaction. Midazolam may or may not be the medication of choice
to reduce the pain and anxiety, but it is evident that further research is needed in order to
preoperatively. This is significant to nurses caring for children to provide optimal and quality
care.
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References
Black, B. P. (2014). Professional Nursing Concepts & Challenges (7th ed.). St. Louis, Missouri:
Elsevier Saunders.
Fazi, L., Jantzen, E. C., Rose, J. B., Kurth, C. D., & Watcha, M. F. (2001, January). A
Klein, E. R. (1992). Premedicating children for painful invasive procedures. Journal of Pediatric
Linares, S. B., Garcia, C. M., Ramirez, C. I., Guerrero, R. J., Botello, B., Monroy, T. R., &
http://dx.doi.org/10.1016/j.anpedi.2013.12.006
Niewswiadomy, R. M. (2012). Foundation of Nursing Research (6th ed.). Upper Saddle River,
Quality and Safety Education for Nurses. (2013). Retrieved from www.qsen.org
www.myfsu/ferrisconnect/blackboardlearn
White, K. M., & O’Sullivan, A. (2012). The essential guide to nursing practice. Washington