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PHARMACOLOGY
Approach to Learning
Pharmacology
Trevor AJ, Katzung BG, Kruidering-Hall M , Masters SB. Katzung & Trevor's Pharmacology Examination
& Board Review 10th Ed. New York: McGraw-Hill, 2013.
Bardal KS, Waechter JE, Martin DS. Applied Pharmacology. St. Louis: Saunders, 2011.
Marc Imhotep Cray, M.D. 14
Key Terms and Concepts(5)
Agonist: A drug that activates its receptor upon binding
Affinity and intrinsic activity; whereas, antagonists have affinity but no IA
which drug binds Katzung BG, editor: Basic & Clinical Pharmacology, 12th ed.
New York: McGraw-Hill, 2012; Fig. 1–3.)
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Key Terms and Concepts(6)
Route of administration: Drug may be delivered
intravenously (IV or iv) for delivery directly into bloodstream
intramuscularly (IM), and
subcutaneously (SC)
Medication may be
depot and slow release
inhalant for rapid absorption and delivery to bronchi and lungs
sublingual to bypass first-pass effect
intrathecal for agents that penetrate blood-brain barrier poorly
rectal to avoid hepatic first-pass effect and for N/V, and
topical administration when local effect is desired such as
dermatologic or ophthalmic agents.
Marc Imhotep Cray, M.D. 17
Routes of administration
Integrated Scientific and Clinical Pharmacology: A MS1 & MS2 Course Syllabus and Digital
Guidebook (2015)