Unit 6 Exam – Purkey 2018 MODIFIED Name: _____________________________ Hr: _____

60 points

1. Place a box around the female karyotype and circle the chromosomes in one of the karyotypes that is potentially the
cause of an abnormality. (4 points)

2. Give the name of the chromosomal abnormality that you researched and list two facts about that disorder. (3 points)

3. Answer the following questions about the pedigree shown below. (4 points)

1 2

3 4 5 6 7

8 9 10 12 13 14

a. What is the relationship between 1 and 12?

b. What is the relationship between 4 and 6?

c. Who has the trait (which number(s))?

d. Who is a carrier for the trait (which number(s))?

4. List the components that makeup a DNA molecule. (4 points)

5. Complete the Venn diagram with three points for DNA, three points for RNA, and one point in the middle from the
word bank provided. (8 points)
- Deoxyribose Sugar - G=C - Uracil = Adenine - Ribose Sugar
- Thymine = Adenine - Single Stranded - Double Stranded

DNA vs. RNA

1.

1.

1.

2. 2.

3.

3.
3.

6. Fill the in blanks of central dogma and include the words: replication, translation, transcription, RNA, DNA, and
proteins. (6 points)

a. b. c.

d. e. f.
7. Write the complementary sequence of the following DNA strand. (4 points)

5’ T A C T T A C G G C A T A T C G G T C G G C A A 3’

8. What type of bonds form between amino acids? (2 points)

9. Transcribe the following DNA sequence into RNA and then translate into amino acids with the given codon chart. (8
points)
U C A G
Phenylalanine Serine Tyrosine Cysteine U
U Phenylalanine Serine Tyrosine Cysteine C
Leucine Serine Stop Stop A
Leucine Serine Stop Tryptophan G
Leucine Proline Histidine Arginine U
C Leucine Proline Histidine Arginine C
Leucine Proline Glutamine Arginine A
Leucine Proline Glutamine Arginine G
Isoleucine Threonine Asparagine Serine U
A Isoleucine Threonine Asparagine Serine C
Isoleucine Threonine Lysine Arginine A
Methionine Threonine Lysine Arginine G
Valine Alanine Aspartic Acid Glycine U
G Valine Alanine Aspartic Acid Glycine C
Valine Alanine Aspartic Acid Glycine A
Valine Alanine Aspartic Acid Glycine G

DNA  TAC GGT CTT CGT CCC TAA CGC TGT ATT

RNA 

Protein 
10. Circle the type of mutation that best describes the mutation. (4 points)

5’ AAC GGT TTA AGA 3’

3’ TTG CCA ATT CT 5’

Insertion Deletion Base Substitution

5’ TAC GGA TTT ATC CTG 3’

3’ ATG CCT AAA TCG GAC 5’

Insertion Deletion Base Substitution

11. Give an example of a mutagen. (2 points)

12. Identify which row of DNA matches the following people after gel electrophoresis. (3 points)

Victim Sample A B C D Identical twin of the victim:

of killer

Father of the victim:

Killer of the victim:

13. Match the following terms to their correct description by writing the letter on the line next to the description. (8
points)
a. Watson & Crick b. Rosalind Franklin c. Somatic Mutation d. Germ Mutation
e. DNA Helicase f. RNA Polymerase g. tRNA h. rRNA

_______ Binds mRNA and tRNA together.

_______ Occurs in body cells and only the individual is affected.

_______ Scientist who took the first photo of the DNA structure.

_______ Helps the mRNA bind to DNA making a sequence for proteins in transcription.

_______ Occurs in sex cells and are transmitted to offspring.

_______ Picks up amino acids and carries them to the ribosome.

_______ Scientists who modeled the double helix structure of DNA and won a Nobel Prize.

_______ Helps unwind or “unzip” DNA during DNA replication.