Salmonella typhy

salmonella typhi (S. typhi) is a Gram-negative bacterium that causes typhoid which is a
preventable communicable disease and still a major global threat to public. Inspite
ofimmunization, estimates for the year 2000 suggested that there were over 2.16 million episodes
of typhoid occurrences world wide resultingin 216,000 death swith more than 90% of morbidity
and mortality from asia.

Symptoms

Symptomsa Patients
aged < 5
Fever All
98 patients
(100) 31 (100) Patients
67 aged >
years
Abdominal pain 56 (57.14) 16 (51.61) 40 (59.70)
5 year
(100)
Vomiting (n49
= (50)
98), n (%) 15 (48.38) 34 (50.74)
Anorexia 30 (30.61) (n 8= (21.05)
31), n
(n22=(32.83)
67),
Cough 13 (13.26) (%)5 (13.15) 8 (11.94)
Body ache 4 3 (9.61) n (%)
1 (1.49)
Headache 3 0 3 (4.47)
(4.08)
Constipation 2 0 2 (2.98)
(3.06)
Irritability 1 0 1 (1.49)
(2.04)
Aphasia 1 0 1 (1.49)
(1.02)
Convulsion 1 0 1 (1.49)
(1.02)
(1.02)
Treatment

Education Health

Typhoid fever continues to be a major health problem resulting in significant number of

children requiring hospi- talization. Public health interventions to minimize human car- rier
contact,safewatersupply,improvedpersonalhygienic measures including health-care behavior
strategies, typhoid vaccination, and rational antibiotic selection based on sen- sitivity pattern to
prevent resistance will help to reduce the morbidity and mortality of this global health problem.