Board review – 1/8/ 2017 - patho 2 1.

vasoconstriction – slow down the velocity of the

Patterns of necrosis.
1. Liquefactive necrosis- usually seen in the brain.
Bacterial infection, suppuration and amoebic
abscess .
2. Gangrenous necrosis - lost of blood supply =
liquefactive + coagulative
a. Wet- associated
b. Dry -
3. Caseous necrosis – coagilative + liquefactive and
associated with TB and is cheesy yellow
4. Fat - pancreas- saponification - yellowish spots
of the fatty tissues.
Lipochrome pigment – wear and tear pigment – old age ,
light brown
blood flow
2. primary hemostatic plug – action of the platelete
aggregation
3. secondary hemostatic plug – more stable
hemostatic plug
4. thrombosis and anti-thrombotic evnets- stop the
excessive accumulation of the thrombus. -
Normal hemostasis
Functions :
1. maintenance of blood in a fluid, clot free state
2. ability to produce hemostatic plug at the site of
vascular injury

Hemosiderin pigments- black pigments. ; iron

Coal – black mockenberg medial calcific sclerosis – calcific deposits

Cholesterol –

1. Exogenous Giant cell arteritis – temple tenderness. Muscular artery

ith luminal narrowing and medial inflammation with
a. Carbon – anthracosis
b. Tattoo lympophycitis . most common in elderly and female.
c. Coal dust – coal worker’s pneumoconiosis Immunologic reaction vs arterial wall,
2. Endogenous Systemic manifestation.
a. lipofuscin
b. melanin
c. hemosiderin
Wegenere’s – multinucleated giant cell.

Kawasaki- very young , pediatric age group – viral in

CHF – widened, congested alveolar capillaries with fection ,headache, fever, lymph node enlargement .
fibrosis, alveolar edema, hemorrhages and hemosiderin avasculatitis – involving the coronary artery
laden macrophages ( chronic passive congestion of the
lungs )

Active hyperemia- arteriolar dilatation

Vasculitis – inflammation of the BV –
Hemostasis pattern –
Few are direct, majority are immune directed .
1. transient vasoconstriction
2. platelet activation
3. activation of coagulation cascade
4. thrombosis Buerger’s disease ( thromboangitis obliterans ) - young,
5. antithrombosis male , .

or
Kawasaki – coronary artery

Polyarteritis nodosa.

Takayasu arteries- aortitis of the