Outbreak

Karen Buri and Lauren Bertelson

Background
Storyline
● Several students at Monarch
University have been infected
○ They have “Zombie-like” symptoms.
○ They do not believe they are infected
■ These beliefs make the infected
difficult to quarantine.
● 4 have died
● Professor Schoep has been infected
https://www.facebook.com/monarchptso
and transformed into a zombie /
● CDC and homeland security have
be called
Symptoms
● “Zombie-like”
● Lethargy/Limited physical ability
● Decomposition of body and skin
● Appetite for humans (particularly brains)
● Pooled blood in extremities
● Loss of reason
● Believe you are a “super soldier” and not
infected
● Altered perception of reality
○ Everyone else moves and talks very fast
https://depositphotos.com/7883483/stock-illustratio
n-cartoon-zombie-isolated-on-white.html
General Information
Bacteria
● Bacteria are spread through contact with
bacteria
○ Airborne, direct contact, ingestion of the bacteria
● Reproduce asexually
○ Each bacteria cell undergoes mitosis and creates
an exact replica of the parent cell
● “Friendly” Bacteria
○ A strain of E.coli, Lactobacilli (probiotics)
https://www.onhealth.com/content/1/bacterial
_infections
● “Bad” Bacteria
○ Anthrax, Staphylococcus Aureus, Tuberculosis
More Bacteria
● Bacteria mutates through changes in DNA
○ These changes can include incorrect DNA
replication, the acceptance of plasmids, natural
selection (usually in relation to antibiotics)
○ Changes in the DNA can make the bacteria more
likely to survive, reproduce and pass the
mutation on
○ This contributes to antibiotic resistance
● Bacteria live in warm, moist
https://www.i-sense.org.uk/infectious-diseases/b
environments, with nutrients for a food acterial-infections/rise-antibiotic-resistance

source
Virus
● Viruses spread through contact
○ Airborne, direct contact
● They mutate through changes in
the genetic sequencing
○ Antigenic drift (minor alterations in the
shape of the antigen)
○ Antigenic shift (Major alterations in
the shape of antigens)
■ Both result in the immune system
not recognising the antigen

https://www.medicalnewstoday.com/articles/158179.php
More Virus
● Because viruses cannot reproduce on
their own, they must invade a host cell
○ Viruses use the host to replicate its RNA or
genetic coding and produce the proteins
necesry to create thes structure for the virus.
● “Friendly” Viruses
○ no virus are beneficial
● “Bad” Viruses
○ influenza, HIV, Ebola, Hantavirus
● Viruses live just about everywhere
http://swandascience.weebly.com/bacteria--viruses.ht
○ They can survive best on non-porous ml
environments (for about 7 days)
Immune system
● Cells involved in the immune system:
○ Lymphocytes (b cells, t cells), macrophages, helper t cells, cytotoxic t cell
● The immune system is comprised of external barriers, non-specific internal
defenses and, specific internal defense
○ External barriers include the skin and mucous membranes, designed to keep microbes from
entering the body
○ Nonspecific internal defenses are fever and inflammation
○ Specific response is when the cells uses antigens to determine if a cell is a foreign cell is and kill
it
More Immune System
● Specific Internal Defenses:
○ Humoral response
■ In the fluids of the body
■ Antigens from the microbe are presented in the surface of a macrophage. The helper t-cell
binds to it and relays the shape of the antigen to the b-cell. The b-cell then produces
antibodies that correspond to the antigen. The antibodies tag the foreign cell and the
macrophages attack them
○ Cell mediated response
■ The helper t-cell is activated by a macrophage that presents the antigens from the foreign
cell on its membrane. This activated helper t-cell then activates the killer t-cells. The killer
t-cells kill the foreign cell by releasing cytotoxins.
Quarantine Plan
Quarantining the General Populace
● Isolate those already infected
○ One wing of hospital sectioned off for those infected
○ Encourage families to isolate the sick
● Enforce curfew
● Require face masks at all times in public
● Fence off infected town to ensure it doesn’t spread past Louisville
● Establish road blockades
● Stop all flights in/out of Colorado
The Cure
Research on Cure
● Scientists sought to create a non-antibiotic cure
in order to avoid the bacteria developing
antibiotic resistance
● Natural medicine as a cure was attempted
instead
○ Scientists used garlic, lavender, nutmeg, cloves
● None of the natural methods worked against
the bacteria
http://www.science-in-amsterdam.nl/en/scienc
● The next step will be to turn to a more
e-programmes/bachelor/10/health_life.html artificially created medicine, like antibiotics
● Hopefully the scientists figure it out before the
bacteria gets to them too… duhn duhn
duuuuuhn
Dissemination of the Cure
● If a cure was found, there are several
effective methods of distributing it
● The best form would be a nasal spray,
because, as opposed to injections, it is
easy for anyone to administer
● Another would be injections, with centers
set up in football stadiums, grocery
stores, town halls, event centers, and
other large public gathering places http://www.coventrytelegraph.net/news/coventry-news/flu-
vaccine-coventry-warwickshire-school-7809422
More Dissemination of Cure
● Lines would be set up to
organize the large amounts of
people, and soldiers would
stand at the ready to maintain
the peace.
● The goal is to have every
person receive the cure in
order to avoid mutated strains
of bacteria http://sfpublicpress.org/news/2009-12/citywide-vaccine-clinic-plans-began-years-ag
o
Bibliography
Bibliography
Where Do Bacteria Live?, www.typesofbacteria.co.uk/where-do-bacteria-live.html.

Study.com, Study.com, study.com/academy/lesson/how-viruses-mutate-antigenic-drift-and-antigenic-shift.html.

Where do Viruses live?,

www.antibioticresistance.org.uk/arfaqs.nsf/2f87bc309e63df2d80256c8c004c707d/2dc84c18539017cc80256ca9004200dd?OpenD

ocument.

“List of Good Bacteria.” Healthy Eating | SF Gate, healthyeating.sfgate.com/list-good-bacteria-7771.html.