BLOOD BANK EXAM 1 FULL

1. The _________ portion of the antibody bind to complement

FC

2. Which immunoglobulin below is most significant for blood banking?

IgG, IgM

3. ABO antibodies are

Naturally occurring antibodies

4. ___________ act at room temperature or lower

IgG

5. If you mix 4 drops of Anti-A and one drop of cell suspension from type “A” patient and
get no reaction after centrifugation, what is the probable explanation?
Zone of equivalence

6. At what temp do IgG antibodies react?

37C

7. What is the purpose of the antihuman globulin (AHG) test in blood banking?
Detects red blood cells coated with antibody

8. When antigen and antibody combine with absence of visible lattice, this is
called________
Sensitization

9. IgM can bind up to 10 antigens on a red cell

True

10. ___________ may be produced after exposure to genetically different nonself antigens of
the same species
Allo antibodies

11. How is it possible for a child to type Rh-negative?

Both parents are Dd

12. Linear strands of DNA wound around histones describe

Chromosomes

13. A gene such as “O”, produces no detectable product is called:

Amorph

14. If your teacher says she is “type A”, then she is referring to her ____________.
Phenotype

15. How many chromosomes do humans have?

46
16. A woman with blood group A marries with blood group O. first born has blood group O.
the mothers genotypes is probably”
AO

17. ABO group inheritance is controlled and influenced by the

A-genes, B-genes, H-genes (all of the above)

18. Individuals who are homozyhous SESE or heterozygoup Sese genes are called:
Secretors

19. B phenotypes individuals can be homozygous BB or heterozygous BO

True

20. Group AB individuals have A ab and B ab

False

21. Visible ___________ occurs when RBCs are physically joined together by antigen ab
union. this stage depends on pH, temp, avidity
Agglutination

22. ___________ analyzes patient cells for the presence of ABO antigens
Reverse group (back-type)

23. Anti-A from group B individual is primarily what class of immunoglobulin?

IgM

24. Which of the following is not characteristic of abys of the ABO system?
ABO abys do not activate complement

25. Why is reverse grouping typically not done on cord blood?

Antibodies are not present at birth

26. Two drops of serum are added to one drop of A1 cells and two drops of serum are added
to one drop of B cells; the two tubes are centrifuged and show reactivity when read
microscopically. this is an example of:
Reverse grouping

27. Front types show positive reactions with anti-a and anti-b. back types shows negative
reactions. what blood types is consistent with these reactions?
AB

28. What is the only possible phenotypes of the offspring of two o parents?
O

29. Forward grouping is defined as?

Detecting antigens on individual’s RBCs via reagent antisera

What does the hh-genotype refer to?

Bombay
 30. When an ab male mates with an AB female, what could be the genotypes of the
offspring?
AA, BB, AB (all of the above)

31. What substance must be formed first A or B specificity is determined?

H

32. Nucleic acid that controls protein synthesis in all living cells ______
RNA

33. Male/female reproductive cell

Gamete

34. Processing different alleles

Heterozygous

35. genetic information for all organisms

DNA

36. Processing a pair of identical alleles

Homozygous

37. The expression of genes

Phenotype

38. Ka-type of gene that will not express itself if there is presence of dominant allele
Recessive

Fill in the blank

Genotypes Phenotypes
39. AO ____A_____
40. AB ____AB____
41. BB ____B_____
42. OO ____O_____
43. DD ____Rh+___
44. BO ____B_____
45. Dd ____Rh+___
46. AA ____A_____
47. Give one example of a technical error that could result in an abo discrepancy
Making a cell suspension that is too thick

48. You are an MLT working at the Red Cross. a Bombay patient comes in to donate blood.
can any patient receive Bombay?
Yes

49. What types of blood can a Bombay patient receive?

Only bombay