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TREATMENT Splenomegaly
Elevated BP and uric acid
Blood Transfusion Ruddy complexion
Changes in diet
COMPLICATION
Dietary supplement
Thromboses ( brain attack, stroke)
MYELODYSPLASTIC SYNDROME (MDS)
MI
Bleeding
Group of diseases in which bone
marrow does not make enough healthy blood
MEDICAL MANAGEMENT
cells
PHLEBOTOMY – removing enough
RISK FACTORS
blood to diminish blood viscosity and to deplete
iron stores
Being male or white
Being older than 60 years old
WBC DISORDER
Being exposed to heave metals
(mercury, lead)
NEUTROPENIA – decrease production
and increase destruction of neutrophil
SIGNS AND SYMPTOMS
CAUSES
Shortness of breath
Weakness or feeling tired
Infections
Fever
Medications
Disease in bone marrow
DIAGNOSTIC TEST
TREATMENT
Physical Exam
CBC
Chemotherapy
Peripheral blood smear – checked for
Radiation therapy
changes in number, type, shape, and size of
blood cell or too much iron the RBC
PLATELET and COAGULATION DISORDER
Cytogenic analysis – test which cells in
THROMBOCYTOPENIA – low platelet level
sample of blood or bone marrow, look for
certain changes in chromosomes
CAUSES
Bone Marrow Aspiration and biopsy –
Decreased production of platelet
removal of bone marrow, blood, and a small
(infection, alcohol)
piece of bone, (hipbone or breastbone)
Increased destruction of platelets CAUSES OF HEMOPHILIA
(malignant lymphoma)
An inherited disorder, caused by a
Increased platelet consumption (DIC) defect in genes, these genes are located on X
chromosomes, which determine whether a
SIGNS AND SYMPTOMS baby is a boy or a girl.
Bleeding and petechiae- when platelet Woman is a “Carrier” she can pass the
count drops to less than 20,000/mm3 defective gene on to her children
Gingival bleeding Son = 50% will have hemophilia
Excessive menstrual bleeding Daughter – 50% will be a carrier
Bone marrow aspiration and biopsy Man who has hemophilia cannot pass
Excessive platelet destruction – the disorder on to his sons, all of his daughters,
destroyed platelet transfused however will be carriers
HEMOPHILIA – rare inherited bleeding Major s/s are bleeding and bruising
disorder in which the blood does not clot Male w/ severe hemophilia, will bleed
normally heavily after circumcision
Most common s/s in older children and
HEMOPHILIA CAN BE DUE TO adults are bleeding in joints (hemarthrosis)