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medication. Conversely, some experts believe the disorder have undertaken epidemiological studies with various See Articles page 868
could be underdiagnosed and that efforts should be made methods to investigate a relative age effect on ADHD
to improve diagnostic reliability.1,2 Findings of studies in diagnosis, including using prescription data for
different countries have shown that many children who ADHD medication as a proxy for diagnosis. Although
meet diagnostic criteria for ADHD—including impairment some effect was noted in most studies, results have
criteria—never receive a clinical diagnosis.3,4 Rates of been mixed. The study by Sayal and colleagues adds
diagnosis vary considerably both between and within weight to the cumulative evidence in favour of a relative
countries, with many variables affecting the likelihood age effect for ADHD diagnosis.
of diagnosis. One key variable is whether somebody in What are the implications of these findings, and
the child’s world—usually a parent or a teacher—notices should we be concerned? Because most children who
problematic symptoms and raises concerns. are diagnosed with ADHD by paediatricians or child
For a diagnosis of ADHD to be made, as with many psychiatrists are treated with medication—often
developmental disorders, evidence is needed of a for several years—the stakes are high. If behaviour
persistent pattern of cross-situational impairment, congruent with relatively young age within the
meaning functional difficulties attributable to ADHD school year is being systematically misclassified as
symptoms at both home and school.5,6 Therefore, developmental immaturity, many incorrect diagnoses
those who diagnose and treat ADHD—paediatricians, of ADHD could be made, and children might be
psychologists, and child psychiatrists—depend on reports treated unnecessarily with medication. The response
from teachers about the child’s behaviour, developmental to ADHD treatment is non-specific and not dependent
competencies, and performance in school. Standardised on a correct diagnosis—ie, most children treated
questionnaires are designed to evaluate the child’s with stimulant medications show improvement in
behaviour by comparison with his or her peers. For attentional control. Therefore, treating clinicians
example, the commonly used Vanderbilt teacher rating are likely to conclude that medication is effective
scale says: “Each rating should be considered in the and continue prescribing it for some time. As well as
context of what is appropriate for the age of the child you potential exposure to side-effects, other risks of wrong
are rating”. Despite this wording, children’s behaviour diagnosis and treatment include stigmatisation and
is likely to be often calibrated by teachers against grade- missing alternate explanations for academic, social,
level, rather than age-level, expectations. and behavioural difficulties—eg, learning disorders,
In The Lancet Psychiatry, Kapil Sayal and colleagues emotional disturbance, or trauma.
report findings of a study of relative age within the To put the finding of Sayal and colleagues in context,
school year (by month of birth) and ADHD diagnosis.7 it is useful to consider what factors might lead to a child
The authors used data from two national population with ADHD symptoms being referred for assessment.
patient registers to study children from age 7 years With respect to intrinsic child factors, children with
who were born in Finland between 1991 and 2004. combined presentation ADHD—ie, a combination of
Compared with children born in January (reference age), inattentive and hyperactive-impulsive symptoms—are
those born in the later months of the year had higher referred more consistently than are those with only
incidence ratios for ADHD diagnosis. The effect was inattentive symptoms, and boys with ADHD are more
seen in both boys and girls and was more pronounced likely to be identified than are girls.3 Family variables
in recent years. The relative age effect was noted for are also important: the effect of a child’s behaviour on
children diagnosed at age 7–9 years, but not for those the family is one of the main drivers of help-seeking for
diagnosed age 10 years or older. A sensitivity analysis children with ADHD in the community.8 Other variables
showed no difference in findings whether comorbid that might affect access to assessment services for