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Predisposing Factors
Precipitating Factors -Heredity
-Diet (Processed foods) -Age
-Gender (male)
Phase 1 Excretion
Enzyme
Phase II Excretion
detoxification
enzymes
Ultimate Carcinogen
DNA adduct
(DNA+Carcinogen)
Initiation
Mutation
Promotion
Apoptosis
Precancerous lesion
1
Invasive lesion
Progression
Hyperplasia of
prostate periphery
Metastasis
at the testes
Atrophy of
the testis
Adenocarcinoma
of the testes
If untreated If treated
Further Medication
metastasis regimen / Surgical
removal of
adenocarcinoma
Wellness
2
3