Name: Dinda 01

Exercise 4: Endocrine System Physiology: Activity 1: Metabolism and Thyroid Hormone Lab Report

Pre-lab Quiz Results

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Experiment Results
Predict Question:
Predict Question 1: Make a prediction about the basal metabolic rate (BMR) of the remaining rats compared with the BMR
of the normal rat you just measured.
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Predict Question 2: What do you think will happen after you inject thyroxine into the three rats?
You did not answer this question.

Predict Question 3: What do you think will happen after you inject TSH into the three rats?
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Predict Question 4: Propylthiouracil (PTU) is a drug that inhibits the production of thyroxine by blocking the attachment of
iodine to tyrosine residues in the follicle cells of the thyroid gland (iodinated tyrosines are linked together to form thyroxine).
What do you think will happen after you inject PTU into the three rats?
You did not answer this question.

Stop & Think Questions:

1h. Calculate the oxygen consumption per hour for this rat using the following equation.

ml O2 consumed/1 minute x 60 minutes/hour = ml O2/hour

Enter the oxygen consumption per hour in the field below and then click Submit Data to display your results in the Lab
Report.
You did not answer this question.1i. Now that you have calculated the oxygen consumption per hour for this rat, you can
calculate the metabolic rate per kilogram of body weight with the following equation (note that you need to convert the
weight data from grams to kilograms to use this equation).

Metabolic rate = (ml O2/hr)/(weight in kg) = ml O2/kg/hr

Enter the metabolic rate in the field below and then click Submit Data to display your results in the Lab Report.
You did not answer this question.2h. Calculate the oxygen consumption per hour for this rat using the following equation.

ml O2 consumed/1 minute x 60 minutes/hour = ml O2/hour

Enter the oxygen consumption per hour in the field below and then click Submit Data to display your results in the Lab
Report.
You did not answer this question.2i. Now that you have calculated the oxygen consumption per hour for this rat, you can
calculate the metabolic rate per kilogram of body weight with the following equation (note that you need to convert the
weight data from grams to kilograms to use this equation).

Metabolic rate = (ml O2/hr)/(weight in kg) = ml O2/kg/hr

Enter the metabolic rate in the field below and then click Submit Data to display your results in the Lab Report.
You did not answer this question.3h. Calculate the oxygen consumption per hour for this rat using the following equation.

ml O2 consumed/1 minute x 60 minutes/hour = ml O2/hour

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Enter the oxygen consumption per hour in the field below and then click Submit Data to display your results in the Lab
Report.
You did not answer this question.3i. Now that you have calculated the oxygen consumption per hour for this rat, you can
calculate the metabolic rate per kilogram of body weight with the following equation (note that you need to convert the
weight data from grams to kilograms to use this equation).

Metabolic rate = (ml O2/hr)/(weight in kg) = ml O2/kg/hr

Enter the metabolic rate in the field below and then click Submit Data to display your results in the Lab Report.
You did not answer this question.Judging from their basal metabolic rates (an indicator of thyroid function), categorize the
rats as hypothyroid (low thyroid levels; BMR below 1600), euthyroid ("good," or normal, thyroid levels; BMR = 1650-1750),
or hyperthryoid (high thyroid levels; BMR above 1800).

The normal rat is

You did not answer this question.
Correct answer: b. euthyroid

Judging from their basal metabolic rates (an indicator of thyroid function), categorize the rats as hypothyroid (low thyroid
levels; BMR below 1600), euthyroid ("good," or normal, thyroid levels; BMR = 1650-1750), or hyperthryoid (high thyroid
levels; BMR above 1800).

The thyroidectomized (Tx) rat is

You did not answer this question.
Correct answer: a. hypothyroid

Judging from their basal metabolic rates (an indicator of thyroid function), categorize the rats as hypothyroid (low thyroid
levels; BMR below 1600), euthyroid ("good," or normal, thyroid levels; BMR = 1650-1750), or hyperthryoid (high thyroid
levels; BMR above 1800).

The hypophysectomized (Hypox) rat is

You did not answer this question.
Correct answer: a. hypothyroid

4c. Calculate the oxygen consumption per hour for this rat using the following equation.

ml O2 consumed/1 minute x 60 minutes/hour = ml O2/hour

Enter the oxygen consumption per hour in the field below and then click Submit Data to display your results in the Lab
Report.
You did not answer this question.4d. Now that you have calculated the oxygen consumption per hour for this rat, you can
calculate the metabolic rate per kilogram of body weight with the following equation (note that you need to convert the
weight data from grams to kilograms to use this equation).

Metabolic rate = (ml O2/hr)/(weight in kg) = ml O2/kg/hr

Enter the metabolic rate in the field below and then click Submit Data to display your results in the Lab Report.
You did not answer this question.5c. Calculate the oxygen consumption per hour for this rat using the following equation.

ml O2 consumed/1 minute x 60 minutes/hour = ml O2/hour

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Enter the oxygen consumption per hour in the field below and then click Submit Data to display your results in the Lab
Report.
You did not answer this question.5d. Now that you have calculated the oxygen consumption per hour for this rat, you can
calculate the metabolic rate per kilogram of body weight with the following equation (note that you need to convert the
weight data from grams to kilograms to use this equation).

Metabolic rate = (ml O2/hr)/(weight in kg) = ml O2/kg/hr

Enter the metabolic rate in the field below and then click Submit Data to display your results in the Lab Report.
You did not answer this question.6c. Calculate the oxygen consumption per hour for this rat using the following equation.

ml O2 consumed/1 minute x 60 minutes/hour = ml O2/hour

Enter the oxygen consumption per hour in the field below and then click Submit Data to display your results in the Lab
Report.
You did not answer this question.6d. Now that you have calculated the oxygen consumption per hour for this rat, you can
calculate the metabolic rate per kilogram of body weight with the following equation (note that you need to convert the
weight data from grams to kilograms to use this equation).

Metabolic rate = (ml O2/hr)/(weight in kg) = ml O2/kg/hr

Enter the metabolic rate in the field below and then click Submit Data to display your results in the Lab Report.
You did not answer this question.Judging from their basal metabolic rates (an indicator of thyroid function), categorize the
rats as hypothyroid (low thyroid levels; BMR below 1600), euthyroid ("good," or normal, thyroid levels; BMR = 1650-1750),
or hyperthryoid (high thyroid levels; BMR above 1800) after the thyroxine injection.

The normal rat is

You did not answer this question.
Correct answer: c. hyperthyroid

Judging from their basal metabolic rates (an indicator of thyroid function), categorize the rats as hypothyroid (low thyroid
levels; BMR below 1600), euthyroid ("good," or normal, thyroid levels; BMR = 1650-1750), or hyperthryoid (high thyroid
levels; BMR above 1800) after the thyroxine injection.

The thyroidectomized (Tx) rat is

You did not answer this question.
Correct answer: c. hyperthyroid

Judging from their basal metabolic rates (an indicator of thyroid function), categorize the rats as hypothyroid (low thyroid
levels; BMR below 1600), euthyroid ("good," or normal, thyroid levels; BMR = 1650-1750), or hyperthryoid (high thyroid
levels; BMR above 1800) after the thyroxine injection.

The hypophysectomized (Hypox) rat is

You did not answer this question.
Correct answer: c. hyperthyroid

Which of the rats developed a goiter after injection with thyroxine (select all that apply)?
You did not answer this question.
Correct answer: d. None of the rats developed a goiter with this injection.

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7c. Calculate the oxygen consumption per hour for this rat using the following equation.

ml O2 consumed/1 minute x 60 minutes/hour = ml O2/hour

Enter the oxygen consumption per hour in the field below and then click Submit Data to display your results in the Lab
Report.
You did not answer this question.7d. Now that you have calculated the oxygen consumption per hour for this rat, you can
calculate the metabolic rate per kilogram of body weight with the following equation (note that you need to convert the
weight data from grams to kilograms to use this equation).

Metabolic rate = (ml O2/hr)/(weight in kg) = ml O2/kg/hr

Enter the metabolic rate in the field below and then click Submit Data to display your results in the Lab Report.
You did not answer this question.8c. Calculate the oxygen consumption per hour for this rat using the following equation.

ml O2 consumed/1 minute x 60 minutes/hour = ml O2/hour

Enter the oxygen consumption per hour in the field below and then click Submit Data to display your results in the Lab
Report.
You did not answer this question.8d. Now that you have calculated the oxygen consumption per hour for this rat, you can
calculate the metabolic rate per kilogram of body weight with the following equation (note that you need to convert the
weight data from grams to kilograms to use this equation).

Metabolic rate = (ml O2/hr)/(weight in kg) = ml O2/kg/hr

Enter the metabolic rate in the field below and then click Submit Data to display your results in the Lab Report.
You did not answer this question.9c. Calculate the oxygen consumption per hour for this rat using the following equation.

ml O2 consumed/1 minute x 60 minutes/hour = ml O2/hour

Enter the oxygen consumption per hour in the field below and then click Submit Data to display your results in the Lab
Report.
You did not answer this question.9d. Now that you have calculated the oxygen consumption per hour for this rat, you can
calculate the metabolic rate per kilogram of body weight with the following equation (note that you need to convert the
weight data from grams to kilograms to use this equation).

Metabolic rate = (ml O2/hr)/(weight in kg) = ml O2/kg/hr

Enter the metabolic rate in the field below and then click Submit Data to display your results in the Lab Report.
You did not answer this question.Judging from their basal metabolic rates (an indicator of thyroid function), categorize the
rats as hypothyroid (low thyroid levels; BMR below 1600), euthyroid ("good," or normal, thyroid levels; BMR = 1650-1750),
or hyperthryoid (high thyroid levels; BMR above 1800) after the TSH injection.

The normal rat is

You did not answer this question.
Correct answer: c. hyperthyroid

Judging from their basal metabolic rates (an indicator of thyroid function), categorize the rats as hypothyroid (low thyroid
levels; BMR below 1600), euthyroid ("good," or normal, thyroid levels; BMR = 1650-1750), or hyperthryoid (high thyroid

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levels; BMR above 1800) after the TSH injection.

The thyroidectomized (Tx) rat is

You did not answer this question.
Correct answer: a. hypothyroid

Judging from their basal metabolic rates (an indicator of thyroid function), categorize the rats as hypothyroid (low thyroid
levels; BMR below 1600), euthyroid ("good," or normal, thyroid levels; BMR = 1650-1750), or hyperthryoid (high thyroid
levels; BMR above 1800) after the TSH injection.

The hypophysectomized (Hypox) rat is

You did not answer this question.
Correct answer: c. hyperthyroid

Which of the rats developed a goiter after injection with TSH (select all that apply)?
Your answer: c. the hypophysectomized rat
Correct answer: a. the normal rat c. the hypophysectomized rat

10c. Calculate the oxygen consumption per hour for this rat using the following equation.

ml O2 consumed/1 minute x 60 minutes/hour = ml O2/hour

Enter the oxygen consumption per hour in the field below and then click Submit Data to display your results in the Lab
Report.
You did not answer this question.10d. Now that you have calculated the oxygen consumption per hour for this rat, you can
calculate the metabolic rate per kilogram of body weight with the following equation (note that you need to convert the
weight data from grams to kilograms to use this equation).

Metabolic rate = (ml O2/hr)/(weight in kg) = ml O2/kg/hr

Enter the metabolic rate in the field below and then click Submit Data to display your results in the Lab Report.
You did not answer this question.11c. Calculate the oxygen consumption per hour for this rat using the following equation.

ml O2 consumed/1 minute x 60 minutes/hour = ml O2/hour

Enter the oxygen consumption per hour in the field below and then click Submit Data to display your results in the Lab
Report.
You did not answer this question.11d. Now that you have calculated the oxygen consumption per hour for this rat, you can
calculate the metabolic rate per kilogram of body weight with the following equation (note that you need to convert the
weight data from grams to kilograms to use this equation).

Metabolic rate = (ml O2/hr)/(weight in kg) = ml O2/kg/hr

Enter the metabolic rate in the field below and then click Submit Data to display your results in the Lab Report.
You did not answer this question.12c. Calculate the oxygen consumption per hour for this rat using the following equation.

ml O2 consumed/1 minute x 60 minutes/hour = ml O2/hour

Enter the oxygen consumption per hour in the field below and then click Submit Data to display your results in the Lab

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Report.
You did not answer this question.12d. Now that you have calculated the oxygen consumption per hour for this rat, you can
calculate the metabolic rate per kilogram of body weight with the following equation (note that you need to convert the
weight data from grams to kilograms to use this equation).

Metabolic rate = (ml O2/hr)/(weight in kg) = ml O2/kg/hr

Enter the metabolic rate in the field below and then click Submit Data to display your results in the Lab Report.
You did not answer this question.Judging from their basal metabolic rates (an indicator of thyroid function), categorize the
rats as hypothyroid (low thyroid levels; BMR below 1600), euthyroid ("good," or normal, thyroid levels; BMR = 1650-1750),
or hyperthryoid (high thyroid levels; BMR above 1800) after the PTU injection.

The normal rat is

You did not answer this question.
Correct answer: a. hypothyroid

Judging from their basal metabolic rates (an indicator of thyroid function), categorize the rats as hypothyroid (low thyroid
levels; BMR below 1600), euthyroid ("good," or normal, thyroid levels; BMR = 1650-1750), or hyperthryoid (high thyroid
levels; BMR above 1800) after the PTU injection.

The thyroidectomized (Tx) rat is

You correctly answered: a. hypothyroid

Judging from their basal metabolic rates (an indicator of thyroid function), categorize the rats as hypothyroid (low thyroid
levels; BMR below 1600), euthyroid ("good," or normal, thyroid levels; BMR = 1650-1750), or hyperthryoid (high thyroid
levels; BMR above 1800) after the PTU injection.

The hypophysectomized (Hypox) rat is

Your answer : b. euthyroid
Correct answer: a. hypothyroid

Which of the rats developed a goiter after injection with PTU (select all that apply)?
You correctly answered: a. the normal rat

Experiment Data:

Rat Weight (g) ml O2/min ml O2/hr BMR Palpation Injected

(ml O2/kg/hr)
Normal 251 7.0 420.00 1673.31 No Mass none
Tx 245 6.3 378.00 1542.86 No Mass none
Hypox 246 6.3 378.00 1536.59 No Mass none
Normal 251 8.4 504.00 2007.97 No Mass thyroxine
Tx 245 7.8 468.00 1910.20 No Mass thyroxine
Hypox 246 7.9 474.00 1926.83 No Mass thyroxine
Normal 251 8.0 480.00 1912.35 Mass TSH
Tx 245 6.3 378.00 1542.86 No Mass TSH
Hypox 246 7.9 474.00 1926.83 Mass TSH
Normal 251 6.2 372.00 1482.07 Mass ptu
Tx 245 6.2 372.00 1518.37 No Mass ptu

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 Rat Weight (g) ml O2/min ml O2/hr BMR Palpation Injected
(ml O2/kg/hr)
Hypox 246 6.4 384.00 1560.98 No Mass ptu

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Post-lab Quiz Results
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Review Sheet Results
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