Adipose Stem Cell Therapy

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Copyright © 2011 Stem Cell Rejuvenation Center

Stem Cell Rejuvenation Center

U.S.A. Treatment Center: Adipose Stem Cell Therapies and Treatments

What is an Autologous Adipose Stem Cell Procedure?

A small sample of Adipose tissue (fat) is removed from above the Superior Iliac spine (love handles) or
abdomen under a local anesthetic.

Obtaining Adipose-Derived Stem Cells (ADSCs) is much easier and less invasive than
performing a bone marrow extraction. In addition, adipose tissue contains much larger
volumes of mesenchymal stem cells than does bone marrow. We use the patient's own
adipose tissue to extract the stem cells. Autologous means that the donor and the recipient are
the same person.

Benefits of ADSCs: Stem cells play an integral part in wound healing and regeneration of
tissue at the cellular level.

The Major Advantages of Adipose Stem Cell Therapy:

 *Our technology allows us to complete the entire procedure on the same day, using
less than minimally manipulated methods.
 *High Yield: A high-dose of stem cells can be obtained in just a couple of hours.
 *Mesenchymal stem cell yields from peripheral fat are much higher than from bone
marrow.
 *Patients receive their own autologous cells, so there is a very low risk of immune
rejection.
 *A minimally invasive outpatient procedure makes it easier to harvest from fat than
from bone marrow and more comfortable for patients.

Is this procedure a significant improvement on other treatments currently available?

Yes – We can now obtain Adult Stem Cells (ASCs) from a fat sample. This in-clinic
treatment is completed the same day, and there is no need to ship samples to an outside
laboratory and wait days for the cells to be returned for an injection on a second visit. This
faster process provides increased stem cell counts, without manipulation.

Is an Autologous Adipose Stem Cell Procedure Safe?

Yes… because the adipose tissue is removed from one's own body via sterile technique and
remains in a controlled environment there are no problems with cell rejection or disease
transmission. The interview, physical, harvesting, and administration of stem cells are all
performed in-house under a physician’s control.

How do I know if stem cell therapy is right for me?

Discussing treatment options with your physician is an important first step in making a
decision regarding stem cell therapy. Potential outcomes, an integrative and comprehensive
treatment plan, and financial costs are all factors to consider.

I have heard Stem Cell Treatments are VERY expensive, can I afford this?

Yes you can!

Due to our advanced adult stem cell technology provided in the form of an “in house”
procedure, our Stem Cell Center can now provide this service at a fraction of the cost
previously incurred. Even better, it’s a same day procedure. We offer the entirety of our
treatment in Phoenix, Arizona - USA and we have been able to lower our cost to a flat rate of
$7,600.00 per treatment (including consultation). Fees are subject to change and some more
complex procedures may incur additional costs.

Why Choose an Adipose Stem Cell Procedure?

Adipose-derived mesenchymal stem cells are easier to harvest than bone marrow and can be
obtained in much larger quantities. In addition, it is much less painful and involves lower
risks.

*There is a much shorter time from extraction to the administration of treatment. No

culturing or manipulation is needed using our procedure, as opposed to a bone marrow
extraction which requires days or weeks to reach the necessary therapeutic threshold.

*There are no ethical or moral issues involved in harvesting autologous Adult Stem Cells
(ASCs).
Are There Detrimental Side Effects from an Adipose Stem Cell Procedure?

No, the adipose tissue is extracted from the patient’s own body so no ‘foreign’ donors are
used. This minimizes the potential for immune rejection. Our procedure is performed
completely in-house and administered by licensed physicians here in the United States.
Please keep in mind that every procedure does have its risks, but we do practice sterile
technique which makes the risk of infection very low. In fact, we have not had any infections
develop in any of the stem cell patients we have treated as we take great care in keeping a sterile
environment.

What You Can Expect When Visiting the Stem Cell Rejuvenation Center:

 Consultation: Each patient receives a consultation lasting up to 1 1/2 hours prior to

the treatment: History, Medications, Patient desires and expected outcomes are
discussed.
 Harvest: Using a tumescent anesthetic, a sample of adipose tissue is collected from
the patient.
 PRP: If needed, it is isolated from the patient's own blood.
 Stem Cells: Our laboratory staff will isolate the Adult Stem Cells (ASCs) and other
progenitor cells in a sterile environment from the collected fat sample ensuring that no
contamination occurs. There is a difference between aspetic and sterile technique. It
is extremely important to note that sterility means that the cells are not exposed to air
particles and contaminants.
 Prepare: If the doctor wishes, she/he will offer antioxidant and nutritional IV's prior
to infusion to prepare the patient for the therapy.
 Infuse: The cells are then administered back to the patient through one or more of the
following modes of administration:
o Intravenous: The Stem Cells are administered via an intravenous push
o Localized: The Stem Cells are administered directly into a localized area.
o Intramuscular: The Stem Cells are implanted into the muscle.
o Intranasal: This therapy relies on direct transmission through the cribiform
plate, bypassing the Blood Brain Barrier, along the olfactory and trigeminal
nerve pathways.

Differences Between An Adipose And A Bone Marrow Procedure:

 Less painful than a bone marrow transplant

 More Mesenchymal Stem Cells per unit volume can be harvested
Autologous Growth Factor Components of PRP:

 PRP (Platelet Rich Plasma) contains many growth factors, and has been successfully
used clinically to improve hard and soft tissue healing
 TGF-αβ (Transforming growth factor alpha & beta)
 EGF (Epidermal growth factor)
 FGF (Fibroblast growth factor)
 IGF (Insulin growth factor)
 PDEGF (platelet derived epidermal growth factor)
 PDAF (platelet derived angiogenesis factor)
 IL-8 (Interleukin-8)
 TNF-α (Tumor necrosis factor alpha)
 CTGR (Connective tissue growth factor)GM-CSF (Granulocyte macrophage colony
stimulating factor)
 KGF (Keratinocyte growth factor)
 High concentration of leukocytes (neutrophils, eosinophils) for microbicidal events
 High concentration of wound macrophages and other phagocytic cells, for biological
debridement
 Histamines, Serotonin, ADP, Thromboxane A2, and other vasoactive and chemotactic
agents
 High platelet concentration and native fibrinogen concentration for improved
hemostasis

 Disclaimer: Even though our Treatments are done using autologous cells, our Stem
Cell Therapies are not approved by the FDA. Stem Cell Treatments are not a cure for
any condition, disease or injury, nor a substitute for proper medical diagnosis and care.
Again, Stem Cell Treatments are not a cure for any condition, disease or injury, nor a substitute for proper medical
diagnosis and care. The information we communicate is not medical advice. It is intended to be used for educational
and information purposes only. We do not use collagenase in our stem cell treatment. It’s important for you to do
your own research based on the options that we present to you so that you can make an informed decision.