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Central Retinal Vein Occlusion- is a common cause of vision loss in older individuals, and the second most common

retinal vascular disease after


diabetic retinopathy1. There are two distinct types, classified according to the site of occlusion: in central RVO (CRVO), the occlusion is at or
proximal to the lamina cribrosa of the optic nerve, where the central retinal vein exits the eye2.

Predisposing: Precipitating:

- Inflammation
- Age: 50 Years and - Disease conditions such
older as: Atherosclerosis,
- Hypertension Sarcoidosis, etc.
- Smoking
- Diabetes mellitus
- Glaucoma

LEGEND:
Neurovascular
DISEASE PROCESS
compression of central
retinal vein and optic
SIGNS & SYMPTOMS nerve at scleral outlet

MEDICAL
INTERVENTIONS Increased turbulence
And
Narrowed venous lumen
DIAGNOSTICS

Venous thrombosis
Venous blockage

Neovascular glaucoma Back pressure on


capillaries - Fluorescein
Angiography

carbonic anhydrase - Optical


Release vascular endothelial
inhibitors, aka. Anti- growth factor leading to Coherence
Glaucoma agents eg.
Endothelial junction dysfunction Tomography
Acetazolamide - Fundus Auto
(Acetazolam) fluorescence
Vein occlusion occurs

Macular aeodema Sudden, unilateral


Mild to moderate loss of acuity, blurred vision
usually 20/200 or better

Intravitreal steroid Injection

(Triamcinolone acetonide) - Retinal laser photocoagulation

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