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REUTERS

DISRUPTIVE,
GAME-CHANGING
INNOVATION

2016 State of Innovation


“ Valeo’s ambition is to bring the most innovative technologies into the
cars that are driven every day by hundreds of millions of people.
One definition perfectly describes our approach: innovation as an
invention that has found a market…In a world that is more and more
open, we promote an innovation of the widest possible scope, including
partnerships with public research bodies, academic organizations,
customers, and suppliers.”
—Jacques Aschenbroich, CEO, Valeo
TABLE OF CONTENTS

Introduction..................................................................................................................................... 4

Observations & Findings............................................................................................................. 5-6

Aerospace & Defense............................7-12 Information Technology....................43-48

Automotive..........................................13-18 Medical Devices.................................49-54

Biotechnology....................................19-24 Oil & Gas........................................... 55-60

Cosmetics & Wellbeing.....................25-30 Pharmaceuticals................................61-66

Food, Beverage & Tobacco................ 31-36 Semiconductors.................................67-72

Home Appliances.............................. 37-42 Telecommunications..........................73-78


DISRUPTIVE INNOVATIONS LEAD
DOUBLE-DIGIT GROWTH

It takes a village to do a lot of things these days, and innovation is no exception.


2015 was the year of many innovative firsts and it took lots of villages to get there. In fact,
innovation over the last year was one of the most active in history with double-digit growth of
13.7 percent. This jump was the result of lots of villages working to find better ways of doing
things and breakthrough science, technology and medicine. It was the year of Collabovation.

Defining the trend These firsts were possible because of the massive investment
Collabovation is a term used to represent the elegant in innovation–in collabovation–made by organizations
convergence of collaboration, innovation, cultivation, around the world. Overall, global innovation activity saw a
cross-pollination and calibration, swirled into the powerful notable uptick over the last year, with Medical Devices, Home
process of bringing inventions to life with strategic partners Appliances and Aerospace leading the charge. These sectors
and suppliers. Coming up with a novel idea can be a feat all experienced year-over-year, double-digit growth, as did
in itself, but actually bringing one to market is an entirely Information Technology and Oil & Gas. In fact, every sector
different game. The Lifecycle of Innovation, from discovery was in the black outside one: Biotechnology, which decreased
and protection to commercialization and launch, involves slightly given a leveling off in that industry.
everything from research and prototyping to intellectual-
property protection and product monetization. In today’s Moving the needle
fast-paced world of science, technology and medicine, where
Collabovation is happening between corporations
disruption and multi-tiered competition are the norm, it takes
and universities. Government agencies and research
collabovation to truly succeed.
centers. Start-ups and bellwethers. Physical and mental
boundaries are being lifted. Like-minded, similar-goaled
Breaking through organizations are finding each other. A web of information
Think of the many breakthroughs that happened over the is aligning partners and best practices in an effort to
last year. It was the first time astronauts from different collaboratively innovate.
countries embarked on the longest human space mission This report showcases some of these instances, as well as
by two men: American Scott Kelly and Russian Mikhail uncovers key innovation trends for 2016. Examination of
Kornienko, occupying the International Space Station for global patent activity provides a glimpse into what’s hot,
nearly a year. It was the first time self-driving cars were what’s not, what’s coming next, who leads and which
tested on public roadways in certain jurisdictions around the regions are the most active.
world. And, the first time a biosimilar drug was approved in
Welcome to the 2016 State of Innovation. We invite you
the US, while certain other drugs were being tested on 3D
to ponder these pages and consider new partners with
printers. It was also the year when the Internet of Things (IoT)
whom to collabovate.
garnered mass appeal, allowing homeowners to manage their
dwellings with omnipotent-like intelligence, while cloud
storage became mainstream.
Vincent J. Caraher,
President,
Thomson Reuters IP & Science

2016 State of Innovation stateofinnovation.com Introduction 4


OBSERVATIONS & FINDINGS

Up, up and away Figure 2: Percentage Growth in


Global innovation activity experienced gains across 11 of the Innovation Activity (2009–2015)
12 sectors throughout 2015, with the largest leaders being
Medical Devices, Home Appliances and Aerospace & Defense. 150.00%

This rebound follows prior year declines for Medical Devices


and Aerospace, which had year-over-year innovation drops of
120.00%
5 percent and 1 percent, respectively, while Home Appliances
was flat. Semiconductor activity also fell in 2014, but saw a
bump of 3 percent in 2015. 90.00%

The longer-term view, covering the seven years from


2009–2015 (inclusive), highlights just how robust and active
60.00%
innovators have been. The combined output across all 12
technology areas was on a consistent upward climb (Figure
1). The largest overall increase for the extended period was in 30.00%

Food, Beverage & Tobacco, which skyrocketed 128.25 percent.


Aerospace & Defense and Home Appliances also experienced
triple-digit jumps, as shown in Figure 2. 0.00%

All Technology
Aerospace

Automotive

Biotechnology

Information Technology

Cosmetics & Wellbeing

Home Appliances

Medical Devices

Pharmaceuticals

Semiconductors
Food, Beverage & Tobacco

Oil & Gas

Telecommunications
Figure 1: Global Innovation Output
Across 12 Sectors (2009–2015)
Source: Derwent World Patents Index
2,500,000

This longer-view shift is indicative of how our world has been


evolving. For example, the production of disease-resistant
2,000,000 crops and genetically modified foods, aimed at ensuring an
ample food supply for a world population projected to hit
10 billion later this century. The development of appliances
that communicate with one another and reflect their owners’
preferences; the actualization of the IoT. The quest to explore
1,500,000
space, understand the universe beyond our galaxy and find
new frontiers for future humans—as well as equip defense
teams for wars that require continued military investment.

Research & Innovation


1,000,000
2009 2010 2011 2012 2013 2014 2015

Source: Derwent World Patents Index and Thomson Innovation The relationship between research and innovation is well
understood. Analysis shows that scientific and scholarly
research typically precedes discovery and the protection
Sign of the Times of innovation rights by a few years. It’s therefore prudent to
Looking across this seven-year span, it’s clear the figures look at what topics, institutions and regions lead globally
reflect a sign of the times. The world was rebounding from the in research to get an even richer understanding of what the
greatest economic crisis in the last 75 years, while technology future holds.
had catapulted the Digital Era into the next stratosphere,
A look across the last decade and research related to the
creating opportunities heretofore unknown.
12 technology areas, as contained in the Web of ScienceTM,

2016 State of Innovation stateofinnovation.com Observations & Findings 5


Figure 3: Scientific Research Output Innovation Drives the Future
Across 12 Technology Areas (2005–2015) Innovation is a driver of economic success and growth.
Companies and countries that consistently invest in innovation
400,000 by prioritizing R&D and allocating funds and resources for this
activity are proven to be more successful than those that don’t.
The Thomson Reuters Top 100 Global Innovators are an
example of this. The honorees of this designation, based on a
350,000 comprehensive, patent-based methodology, have consistently
outperformed the S&P 500 and/or MSCI World Index in terms
of market-cap weighted R&D investment, annual revenue and
employment. And, regions like the UK, which has fewer R&D
300,000
and innovation incentives compared to Germany and Japan,
has not made the Top 100 Global Innovators list in several years.
As the process of innovation becomes more collaborative in our
technologically driven world, it’s hard to imagine the trajectory
250,000
of activity changing in the near future.
2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015
Innovation drives the future. And the future is ours. Innovative
Source: Web of Science
disruptions are a hallmark of the Digital Era. With the proper
balance of discovery, protection and commercialization, these
shows that output related to these topics has returned to its numbers will continue to grow and our world will continue to
pre-economic-crisis levels, as shown in Figure 3. As the tools for evolve before our eyes.
finding prior research become even more refined, researchers
collaborate more with others and pure or basic research
investments are sometimes married with innovation,
causing the scholarly activity to even out.

Overall View of Innovation


2015 2014 %
% Industry
Volume Volume Change
5% Aerospace & Defense 71,633 62,162 15%
12% 166,867 153,872 8% 5%
Automotive 12%
3% Biotechnology 41,624 42,584 -2% 12%

1% Cosmetics & Well Being 11,307 11,017 3%


8% 3%
2% Food, Beverage & 26,605 26,333 1%
1%
Tobacco
2%
6% Home Appliances 86,301 71,278 21%
9% 6%
31% Information Technology 429,806 380,325 13%

9% Medical Devices 118,658 93,462 27% 2%

2% Oil & Gas 27,556 24,158 14%


9%
9% Pharmaceuticals 116,286 111,479 4%

8% Semiconductors 114,488 110,761 3% 31%


30%
12% Telecommunications 166,601 161,739 3%

Source: Derwent World Patents Index

2016 State of Innovation stateofinnovation.com Observations & Findings 6


AEROSPACE & DEFENSE

From dreamliners to space stations to unmanned


military vehicles, the window on our world is changing.

2016 State of Innovation


REUTERS/LUCAS JACKSON stateofinnovation.com Aerospace & Defense 7
COLONIZING THE MILKY WAY

Matt Damon gave us a peek at what life may be like for the first settlers on Mars in the movie
The Martian. As far-fetched as the idea of living on another planet may seem, it’s now projected
that the first humans could inhabit Mars within the next 25 years.1 Such a feat is going to require
an immense amount of innovation and collaboration as earthlings look to colonize Mars, and
potentially other parts of our galaxy.

In fact, it is reported that the US National Aeronautics and an initiative to find private sector partners with which to
Space Administration (NASA) will spend $18.5 billion on explore space in its “Space Exploration as a Driver for Growth
its 2016 space exploration plan.2 Its goals this year include and Competitiveness: Opportunities for the Private Sector,”
increasing utilization of the International Space Station where it states: “ESA is looking into novel ways to advance
(ISS) science and technology hardware by 70 percent and its strategic goals for space exploration, based on strategic
launching 13 science and cargo missions, among many partnerships with the private sector, including entities from
other things. the space and nonspace industry.3 ”

In the race to colonize space, partnerships abound. There are Similarly, articles about NASA partnering with Boeing,
many public/private sector arrangements underway, related Elon Musk’s SpaceX and others reaffirm the commitment
to the Collabovation theme mentioned earlier. The European and passion to make history and be the first to get to Mars,
Space Agency (ESA) recently launched or other parts of the galaxy and universe.

“ The recent ‘Martian’ movie starring Matt Damon is science-fiction in 2016, but with
NASA and ESA actively collaborating with private sector partners such as Boeing
and SpaceX to provide innovative solutions for the financing and execution of space
exploration missions, experts predict that human settlements will be operational on
Mars within 25 years.

Such a highly complex project will require massive innovation across a wide range
of technologies, not just ‘spaceflight’ aspects of aerospace. To sustain and protect
human life in extremely hostile alien environments will involve new solutions for food
and water processing, power generation, communications, healthcare and more, so
partners from ‘non-space’ industry sectors will also be major contributors and this
will in turn drive further innovation for Earth-based applications.”
—George Jack, Engineering Expert, Thomson Reuters

1 http://www.techinsider.io/buzz-aldrin-mars-plan-2016-4
2 https://www.nasa.gov/sites/default/files/files/NASA_FY2016_Summary_Brief_corrected.pdf
3 http://esamultimedia.esa.int/docs/hso/ESA_CFI__Space_Exploration_as_a_Driver_for_Growth_and_Competitiveness.pdf

2016 State of Innovation stateofinnovation.com Aerospace & Defense 8


AEROSPACE & DEFENSE OVERVIEW
2%
% Subsectors 2015 2014 % Change 11%

39% Production Techniques 22,392 18,823 19%


23% Advanced Materials 13,002 12,233 6% 12%
13% 7,468 7,136 5% 39%
Structures & Systems
12% Propulsion Plants 6,760 5,894 15%

11% Instrumentation 6,502 6,270 4%


13%
2% Space Vehicles & 1,424 1,156 23%
Satellite Technologies
Source: Derwent World Patents Index
23%

Top 10 Global Innovators–Aerospace & Defense (2015)


Company Country # Inventions
United Technologies Corp US 716
State Grid Corp of China China 715
Airbus Operations France 620
Jiangxi Hongdu Aviation Ind Group Co Ltd China 617
Boeing US 531
General Electric US 424
LG S Korea 392
Siemens Germany 387
Toyota Japan 360
Hyundai S Korea 334
Source: Derwent World Patents Index

Top 10 Space Technology Innovators–Asia (2011-2015)


Company Country # Inventions
Harbin Institute of Technology China 186
Korea Aerospace Research Institute S Korea 163
China Academy Launch Vehicle Technology China 157
Beijing Control Engineering Research Institute China 108
University Beijing Aeronautics & Astronauts China 93
Shanghai Satellite Engineering Institute China 87
Beijing Institute Spacecraft Environmental Engineering China 77
Shanghai Aerospace System Engineering Research Institute China 72
Mitsubishi Electric Japan 69
Beijing Space Aerocraft Collectivity China 69
Source: Derwent World Patents Index

2016 State of Innovation stateofinnovation.com Aerospace & Defense 9


Top 10 Space Technology Innovators–Europe (2011-2015)
Company Country # Inventions
Airbus France 225
Energiya Rocket Russia 113
Information Satellite Systems Reshetnev Russia 80
Thales France 73
Center Nat Etud Spatiales France 42
Mechanical Engineering Research Institute Russia 61
Cosmic Scientific Production Centre Russia 41
Deut Zent Luft & Raumfahrt Germany 32
Snecma France 24
Moscow Mars Experimental Construction Bureau Russia 19
Source: Derwent World Patents Index

Top 10 Space Technology Innovators–North America (2011-2015)


Company Country # Inventions
Boeing US 221
Honeywell US 41
Lockheed Martin US 33
Raytheon US 31
NASA US National Aerospace & Space US 29
Space Systems/Loral US 21
US Navy US 16
Hamilton Sundstrand US 15
Emcore Solar Power US 14
Qualcomm US 12
Source: Derwent World Patents Index

Most Influential Scientific-Research Institutions in Aerospace (2005-2015)


Institution Country # of Papers (WoS) Relative Citation Impact*
University of Michigan System US 468 1.95
United States Department of Energy US 372 1.43
Delft University of Technology Netherlands 414 1.33
University of Texas Austin US 333 1.32
Centre National de la Recherche Scientifique (CNRS) France 551 1.25
Goddard Space Flight Center US 465 1.22
University of Florida US 312 1.21
US Air Force Research Laboratory US 512 1.19
Pennsylvania State University US 403 1.18
Pennsylvania Commonwealth System of Higher Education US 445 1.18
Source: Web of Science
* Citation impact normalized against average for field and year of publication (n = 1.00)

2016 State of Innovation stateofinnovation.com Aerospace & Defense 10


Summary
Innovation activity over the last year reflects man’s quest The international space race is just that, international.
to conquer new frontiers, as well as push the boundaries of The top 10 innovators in this sector hail from the United
our daily flight expectations, with faster, larger and more States, China, France, South Korea, Germany and Japan.
frill-equipped airplanes than ever before. And, they include a mix of expected and unexpected
companies, including United Technologies Corp., Airbus
The Aerospace & Defense sector saw a significant jump and Boeing as well as General Electric, LG Electronics and
of 15 percent over prior year activity, with the largest Toyota, respectively.
jumps occurring in Space Vehicles & Satellite Technologies
(23 percent), followed by Production Techniques The US leads in the impact of its academic research in
(19 percent) and Propulsion Plants (15 percent). There’s aerospace, with 80 percent of the top 10 institutions coming
no denying the race is on to find a sustainable way for from that country. European organizations take the two
humans to inhabit space, as part of global strategies remaining top 10 spots, while Asian institutions are notably
to handle the exploding human population and ill absent from those with impactful contributions.
effects of climate change on earth.

“ [Our most innovative asset is] the shared belief that our products are useful to
society, and that we can help make the world a better place. For example, people
all over the world want to continue to “go places”, and that will only be possible if
we continue to reduce emissions, a very timely challenge…”
—Pierre Fabre, Senior Executive Vice President,
Research & Technology, Innovation Safran

2016 State of Innovation stateofinnovation.com Aerospace & Defense 11


2016 State ofROSSI
REUTERS/MAX Innovation stateofinnovation.com Aerospace & Defense 12
AUTOMOTIVE

As automobiles become more advanced computers,


what’s to become of the pastime of taking a 4-cylinder
combustion engine out for a Sunday drive?

2016 State of Innovation


REUTERS/THOMAS PETER stateofinnovation.com Automotive 13
ARTIFICIAL INTELLIGENCE ON WHEELS

Over the last year, cars have evolved from being some of the most sophisticated computers on
wheels to being advanced artificial-intelligence transportation chariots. Not only do today’s
automobiles give drivers guidance when backing up, adjust to lane creep and intelligently adapt
to weather conditions, they can also identify the mood and, coming soon, consumption habits of
the driver based on steering-wheel sensors. This is all in addition to the vehicle’s already amazing
ability to operate itself independently.

The International Consumer Electronics Show (CES) in Las Auto-collabovation is alive and well. Daily news headlines tout
Vegas, Nevada, US, featured more automobile exhibitors the latest partnerships in this space. For example, Renault
than ever before this year, which brought the show and ARZA, in order to bring the electric vehicle market to
organizers to create a “Vehicle Intelligence Marketplace” Canadian masses5; Ford and Spotify, to enhance the musical
for the first time.4 Such rapid automotive advancement is experience of FordPass customers; and organizations
the result of thousands of hours of research, development, like the Open Automotive Alliance (OAA), which aims to
experimentation and innovation by auto manufacturers and make automotive technology safer, more seamless and
their partners around the world. more intuitive.6

In today’s world, the realities of artificial intelligence stretch


far beyond the reach of IBM’s Watson. We must start to think
of and see our vehicles as the technological masters they are.

“ Increased partnership between traditional vehicle manufacturers and information/


technology companies is already changing autonomous vehicles into advanced
artificial-intelligence transportation chariots that can continually adapt to
environmental conditions and driver ‘likes’. In today’s world, the realities of artificial
intelligence stretch far beyond the reach of IBM’s Watson. We must start to think of
and see our cars for the technological masters they are.”
—Kevin Chapman, Lead Engineering Expert, Thomson Reuters

4 http://www.ces.tech/News/Press-Releases/CES-Press-Release.aspx?NodeID=ebcec984-2cf5-49ad-b7dc-f181cbf49932
5 http://www.automotiveworld.com/news-releases/renault-azra-invests-40-million-canadian-transport-electrification/
6 http://www.openautoalliance.net/#about

2016 State of Innovation stateofinnovation.com Automotive 14


AUTOMOTIVE OVERVIEW
% Subsectors 2015 2014 % Change
21% Alternative Powered Vehicles 37,844 32,973 15%
4% 3%
11% Navigation Systems 19,753 18,538 7% 5% 21%
11% Safety 18,551 18,893 -2%
5%
11% Transmission 20,175 18,484 9%
10% Seats, Seatbelts and Airbags 18,165 13,596 34% 6%
7% Suspension Systems 12,827 11,003 17%
6% Pollution Control 10,114 9,677 5% 6% 11%

6% Steering Systems 10,841 11,599 -7%


5% Engine Design and Systems 7,845 7,334 7% 7%
5% Security Systems 8,627 8,360 3%
11%
4% Braking Systems 7,654 6,831 12% 10%
3% Entertainment Systems 4,659 4,267 30%9% 11%
Source: Derwent World Patents Index

Top 10 Global Innovators–Automotive (2015)


Company Country # Inventions
Toyota Japan 4,214
Hyundai S Korea 2,469
Bosch Germany 2,390
Denso Japan 2,169
Honda Japan 2,039
Ford US 1,837
Daimler Germany 1,575
GM US 1,435
Beiqi Foton China 1,223
Nissan Japan 1,188
Sources: Derwent World Patents Index

Top 10 Alternative-Powered Vehicle Innovators–Asia (2011-2015)


Company Country # Inventions
Toyota Japan 9,807
Hyundai S Korea 2,827
Honda Japan 2,732
Nissan Japan 2,633
Denso Japan 2,591
Samsung S Korea 2,515
LG S Korea 2,051
Panasonic Japan 1,970
Toyoda Japan 1,634
Sumitomo Electric Japan 1,492
Source: Derwent World Patents Index

2016 State of Innovation stateofinnovation.com Automotive 15


Top 10 Alternative-Powered Vehicle Innovators–Europe (2011-2015)
Company Country # Inventions
Bosch Germany 3057
Daimler Germany 1705
Peugeot Citroen France 709
BMW Germany 637
Siemens Germany 624
Renault France 580
Volkswagen Germany 560
Audi Germany 477
Valeo France 411
Continental Germany 386
Source: Derwent World Patents Index

Top 10 Alternative-Powered Vehicle Innovators–North America (2011-2015)


Company Country # Inventions
General Motors (GM) US 1614
Ford US 1517
General Electric US 355
Caterpillar US 168
Johnson Controls Technology US 156
Tesla Motors US 149
DuPont US 117
Remy Technologies US 109
Qualcomm US 88
IBM US 83
Source: Derwent World Patents Index

Most Prolific Scientific Research Institutions in Automotive (2005–2015)


Institution Country # of Papers (WoS)
University of Michigan US 292
Ford Motor Company US 209
Polytechnic University of Turin Italy 187
Technical University of Munich Germany 173
Shanghai Jiao Tong University China 161
Indian Institute of Technology System India 158
Ohio State University US 151
RWTH Aachen Germany 135
Chalmers University of Technology Sweden 134
Seoul National University S Korea 131
Source: Web of Science

2016 State of Innovation stateofinnovation.com Automotive 16


Summary
Automotive innovation accelerated by 8 percent from In terms of alternative-powered vehicle innovation, Japan’s
year-end 2014 to year-end 2015. All but two of the 12 Toyota is in a category almost unto itself with nearly 10,000
subsectors jumped up, with the largest gains in Seats, unique inventions in that area alone last year. The next
Seatbelts & Airbags (34 percent) followed by Suspension closest competitor in that space is Germany’s Bosch,
Systems (17 percent) and Alternative Powered Vehicles with just over 3,000 unique inventions.
(15 percent), respectively.
Germany and France are the only two countries in Europe
Asia continues to dominate the field overall with 60 percent in the top 10 for Alternative-Powered Vehicles, with
of the Top 10 headquartered there. Japan’s Toyota takes Germany taking seven of the 10 spots. The US occupied
the top spot again, followed by the same top-five-priority- all of the top 10 in North America, with GM and Ford
order of last year: Hyundai (South Korea), Bosch (Germany), pulling into the lead.
Denso (Japan) and Honda (Japan).
The most prolific automotive research institutions have a
China joined the top 10 ranks for the first time, coming in more diverse global footprint, representing the US, Italy,
ninth overall with Beiqi Foton, the country’s largest truck Germany, China, India, Sweden and South Korea. Nine of
manufacturer. This is despite recent news of the company’s the top 10 research institutions doing work in this space are
sales down 15.3 percent in March 2016 over the same period the same as the prior year—the newcomer being Chalmers
one year earlier.7 University of Technology in Sweden.

The US, Germany and Japan round out the bottom half
of the Top 10 with Ford (US), Daimler (Germany), GM (US)
and Nissan (Japan) taking sixth, seventh, eighth and tenth
places, respectively.

“ Although driverless vehicles won’t be ruling the roads in 2016, data shows that they
will likely become a reality in the years to come. Our fascination with this emergent
technology continues to abound. There was a time when it was difficult to imagine
the ability to get from one point to another in a vehicle without being completely
alert and in control of the automobile. But if we’ve learned anything in the 21st
century, it’s that technology seems to be boundless, as long as you have the right
collaborators at the helm.”
—Vin Caraher, President, Thomson Reuters IP & Science

7 http://www.reuters.com/article/idUSL3N17A3AE

2016 State of Innovation stateofinnovation.com Automotive 17


REUTERS/TIM WIMBORNE
2016 State of Innovation stateofinnovation.com Automotive 18
BIOTECHNOLOGY

The sequencing of the human genome is leading to


breakthroughs in and beyond medical treatments.
What doesn’t biotech have its hand in today?

2016 State of Innovation stateofinnovation.com Biotechnology 19


GENETICALLY MODIFIED LIFE

Biotechnology experienced a large number of firsts over the last year.

One of the most significant, and potentially most life transforming, was that of the CRISPR
(clustered regularly interspaced short palindromic repeats) initiative and the editing of a human-
embryo germline. CRISPR “interference” involved making targeted modifications to segments of
DNA to alter its immunity. Such work has implications not only for humans, but also for food crops
and other plants and animals.

Another set of firsts involved a series of bio-based approvals There’s no disputing that the advent of biotechnology
by the US Food and Drug Administration (FDA), including the has created an experimental sandbox for everything from
first biospecific antibody: Amgen’s Blincyto; the first biosimilar genetically manipulating DNA to modifying the composition
drug: Novartis’ Zarxio; and the first biotech food animal: of plants and printing drugs using bio-organisms. While this is
Aquabounty Technologies Inc.’s salmon, which grows cutting-edge work, the pace of innovation fell slightly short
faster than farmed fish. of where it was a year earlier.

“ Governments and payers are counting on biosimilars to revolutionize health care by


reducing the cost of important biologics and increasing access to life-saving drugs.
For that to happen, the follow-on biologics (FOBs) will have to deliver the power of
the reference drugs at a price financially strapped countries can afford and gain the
confidence of the marketplace.”
—Mari Serebrov, Regulatory Editor, BioWorld

2016 State of Innovation stateofinnovation.com Biotechnology 20


BIOTECHNOLOGY OVERVIEW

5% 2%

% 10%
% Subsectors 2015 2014
Change
70% General biotechnology 30,197 29,374 3%
13% Diagnosis of diseases 5,614 6,984 -20%
13%
10% Cancer treatment 4,412 4,855 -9%

5% Genetically modified crops 1,969 2,153 -9%


70%
2% Drug discovery 824 951 -13%
Source: Derwent World Patents Index

30%

Top 10 Global Biotechnology Innovators (2015)


Company Country # Inventions
DuPont US 407
University of Jiangnan China 287
Monsanto US 229
Roche Switzerland 203
University of Zhejiang China 200
Rural Development Administration S Korea 191
University of California US 184
Centre National de la Recherche Scientifique (CNRS) France 166
Lanzhou Veterinary Res Inst China Agric China 165
Institut National de la Santé et de la Recherche Médicale (INSERM) France 160
Source: Derwent World Patents Index

Top 10 Biotech-In-Cancer Innovators–Asia (2011-2015)


Company Country # Inventions
Samsung S Korea 104
University Fudan China 103
Seoul National University S Korea 81
University Yonsei S Korea 77
Agency for Science Technology & Research, A*STAR Singapore 74
Korea Research Institute of Bioscience & Biotechnology S Korea 71
University Shanghai Jiaotong China 71
Peking University China 69
Suzhou Puluoda Biological Technology Co China 68
Osaka University Japan 65
Source: Derwent World Patents Index

2016 State of Innovation stateofinnovation.com Biotechnology 21


Top 10 Biotech-In-Cancer Innovators–Europe (2011-2015)
Company Country # Inventions
Roche Switzerland 335
Institut National de la Santé et de la Recherche Médicale (INSERM) France 244
CNRS France 195
Novartis Switzerland 161
Sanofi France 136
UCL Business UK 66
Glaxo Group UK 65
Deutsches Krebsforschungszentrum Germany 59
Bayer Pharmaceutical Germany 56
Yeda Research & Development Company Israel 48
Source: Derwent World Patents Index

Top 10 Biotech-In-Cancer Innovators–North America (2011-2015)


Company Country # Inventions
Genentech US 266
University of California US 241
US Department of Health US 186
University of Texas System US 170
John Hopkins University US 140
Abbvie US 134
Dana Farber Cancer Institute US 127
General Hospital US 116
Harvard US 111
University of Pennsylvania US 109
Source: Derwent World Patents Index

Most Influential Scientific Research Institutions In Biotech (2005-2015)


Institution Country # of Papers (WoS) Category Normalized Citation Impact
Broad Institute US 485 7.43
European Molecular Biology Lab Germany 801 4.46
Massachusetts Institute of Technology US 1,556 4.25
Wellcome Trust Sanger Institute UK 755 4.11
Howard Hughes Medical Institute US 913 4.10
Memorial Sloan Kettering Cancer Center US 375 3.26
Harvard University US 3,288 3.07
Lawrence Berkeley National Lab US 623 3.03
Dana-Farber Cancer Institute US 425 2.90
VA Boston Healthcare System US 594 2.89
Source: Web of Science

2016 State of Innovation stateofinnovation.com Biotechnology 22


Summary
Biotech was the only technology area of the 12 studied The US dominates biotech scientific-and-scholarly research
that decreased its year-over-year innovation output, output with 80 percent of the top 10. The remaining two
experiencing a 2 percent decline over 2014. This is after institutions are from Europe, one of which is headquartered
having had a 7 percent overall increase from 2013. And all in the UK and the other is in Germany. Once again the
but one of the subsectors, General Biotechnology, declined Broad Institute takes the lead spot with the most impactful
from the earlier period, with the steepest drops in the research, whereas MIT was bumped from second to third
Diagnosis of Diseases (20 percent) and Drug Discovery place by the European Molecular Biology Lab.
(13 percent).
It appears that Biotech has leveled off somewhat, but it
China, France, Germany, South Korea and the US lead the remains to be seen whether this sector will pull ahead
world in biotech innovation. China and the US each have again in the future. The technologies are still in early stages
three of the top 10 spots, followed by France with two, while and the players are still coming into their own. One thing
Germany and South Korea split the remaining two. is certain, the industry is one to watch as the output of
its activity is sure to have an immense impact on all life:
Biotechers are clear collabovators. Three of the top 10 human, plant, animal, aquatic and more.
global biotech innovators are universities and seven of the
top 10 are either a university or research center. No other
sector has this mix in its top 10. The trend continues beyond
the global top 10 to regional sub-sector leaders in cancer-
treatment innovation as well, which comprises a mix of
private and public institutions.

“ Collaboration is critical to igniting innovation; we work closely with our customers,


and with each other. Our spirit of collaboration extends to our 46 technology
platforms, which range from adhesives and abrasives, to ceramics and light
management. We leverage those technologies across all our businesses and
subsidiaries to create unique and relevant products for customers.”
—Inge Thulin, Chairman, President & CEO, 3M

2016 State of Innovation stateofinnovation.com Biotechnology 23


2016 State of Innovation stateofinnovation.com Biotechnology 24
COSMETICS & WELLBEING

Computers aren’t the only things getting smarter—your personal


care products are getting to know you, too.

2016 State of Innovation


REUTERS/RAFAEL stateofinnovation.com
MARCHANTE Cosmetics & Wellbeing 25
SOCIAL MEDIA SPURS COSMETICS SECTOR

We live in the era of here-and-now. From Instagram and OoVoo to Snapchat and Vine, social
media and other outlets set new beauty standards with images of the Kardashians, Beyonce and
Taylor Swift leading the way. Selfies and facetime show us daily where we need to primp, plump
and perfect, spurring today’s cosmetic-conscious fad.

The American Society of Plastic Surgeons recently reported from 2000)—and this just starts to scratch the surface
there were 6.7 million Botox procedures done in 2015, of the litany of possible cosmetic surgeries available.8
1 percent more than the prior year, as well as 27.5 thousand
lip-augmentation surgeries (a 48 percent increase from 2000) Bigger is better in today’s beauty-bingeing world,
and 12.7 thousand cheek-implant procedures (up 21 percent and cosmetic innovations are making it all possible.

“ Fuelled by the immediacy and intense magnifying focus of social media images,
being ‘close-up ready’ has never been more desirable nor more demanding.
Consumers are better informed than ever before and have high expectations:
the distinction between cosmetics and pharmaceuticals becomes ever more
blurred year on year and high-tech delivery formulations become the norm.

The instant worldwide exposure of new products and technology has brought
major new players into the market, particularly from the innovative Asian beauty
sector. Maybe the emergence of companies traditionally less known for cosmetics
and personal care shouldn’t be any surprise, as modern high performance beauty
products incorporate cutting-edge pigment formulations, reflective microparticles
and polymers for an Insta-perfect finish.”
—Peta Leggatt, DWPI Content Specialist-Pharmaceuticals, Thomson Reuters

8 http://www.plasticsurgery.org/Documents/news-resources/statistics/2015-statistics/2015-plastic-surgery-statistics-report.pdf

2016 State of Innovation stateofinnovation.com Cosmetics & Wellbeing 26


COSMETICS & WELLBEING OVERVIEW

2% 2%

% 17%
% Subsectors 2015 2014
Change
41% Skin 6,063 5,407 12%
41%
38% Make-up 5,597 5,722 -2%
17% Hair 2,522 2,614 -4%

2% Perfume 289 342 -15%

2% Antiperspirant 264 274 -4%


Source: Derwent World Patents Index 38%

Top 10 Global Innovators–Cosmetics & Well Being (2015)


Company Country # Inventions
LG Household & Healthcare S Korea 315
L'Oreal France 314
Kao Japan 214
Henkel Germany 154
P&G US 144
AmorePacific S Korea 125
Aesthetic Beijing Technology Co China 87
Unilever Netherlands / UK 75
Beiersdorf Germany 73
Kose Japan 70
Source: Derwent World Patents Index

Top 10 Make-Up Innovators–Asia (2011-2015)


Company Country # Inventions
KAO Japan 776
AmorePacific S Korea 534
LG S Korea 397
Shiseido Japan 356
Kose Japan 307
Pola Chem Japan 178
Lion Japan 144
Nippon Menard Keshohin Japan 142
Nippon Oil & Fats Japan 110
Fujifilm Japan 91
Source: Derwent World Patents Index

2016 State of Innovation stateofinnovation.com Cosmetics & Wellbeing 27


Top 10 Make-Up Innovators–Europe (2011-2015)
Company Country # Inventions
L'Oreal France 1,636
Henkel & CO Germany 271
BASF Germany 214
Unilever Netherlands / UK 202
Beiersdorf Germany 198
CNRS France 107
DSM IP Assets BV Netherlands 91
Merck Patent Germany 81
Evonik DeGussa Germany 77
Symrise Germany 52
Source: Derwent World Patents Index

Top 10 Make-Up Innovators–North America (2011-2015)


Company Country # Inventions
Procter & Gamble US 296
DuPont US 156
Dow Corning US 107
Celanese US 99
Avon US 96
Allergan US 91
Johnson & Johnson US 73
Dow Global Technologies US 61
ELC Management US 51
Colgate Palmolive US 41
Source: Derwent World Patents Index

Most Prolific Scientific Research Institutions In Cosmetics (2005–2015)


Institution Country # of Papers (WoS)
University of Sao Paulo Brazil 177
US FDA US 108
Procter & Gamble US 103
Cosmetic Ingredient Review US 102
Seoul National University S Korea 88
Harvard University US 83
Chinese Academy of Sciences China 81
State University of Campinas Brazil 78
University of California Los Angeles US 70
University of California San Francisco US 68
Source: Web of Science

2016 State of Innovation stateofinnovation.com Cosmetics & Wellbeing 28


Summary

Despite plastic surgeons being busier than ever Asia continues to have a strong foothold in this sector, with
(skin-related innovation is up 12 percent), the bulk of the Japan leading the way. Germany has the most significant
cosmetic subsectors dipped over the prior year. Fragrances presence in Europe, as more chemical companies branch
experienced the largest drop, of 15 percent. Nevertheless, into cosmeceuticals. In the US, it’s a combination of
Cosmetics & Well Being came out on the positive side consumer-product and chemical companies that are
overall, with a modest gain of 3 percent over 2014. driving beautification.

The world’s most active Cosmetics & Well Being innovator Brazil once again takes the top spot in terms of cosmetics-
is, surprisingly, South Korea’s LG Household & Healthcare, related scientific research, with the University of Sao Paulo
part of the LG family of businesses focused on helping and State University of Campinas taking the first and
customers realize their “beauty, lifestyle and culture eighth spots in terms of research output, respectively.
dreams.” This is the first time since the inception of the This perhaps isn’t a huge surprise as Brazil is also among
annual State of Innovation that a traditional cosmetics the top five nations in the world in terms of the overall
company has been trumped by a technology-based number of aesthetic plastic surgeries performed annually.9
company, yet another example of an organization (LG)
that’s spreading its wings into tangential areas. There’s no doubt about it: our socially connected world,
technology, nano-particles, new molecular entities and
In the Make-up subsector, L’Oreal leads the pack with more the accessibility of new treatments are driving a boom
than twice as many inventions (1,636) as the next nearest in beautification. The prospects are ripe for this sector to
innovator, KAO (776). This continues L’Oreal’s leadership continue its upward climb. We may not all be look-alikes
streak in Make-up, which it has consistently dominated for Jennifer Aniston, recently named the 2016 World’s
since we’ve been tracking the field. Most Beautiful Woman by People magazine, but today’s
innovations certainly make replicating “that look”
a lot easier.10

“ The French National Center for Scientific Research (CNRS) was established to
carry out research. Performed by more than 1,000 units throughout France and
abroad, this research improves knowledge, some of which results in breakthrough
innovation. Technology transfer is a logical extension of our research activities,
entrusted to more than 30,000 staff and partly led in partnership with industry.”
—Marie-Pierre Comets, Director of Innovation & Business Relations, CNRS

9 http://www.prnewswire.com/news-releases/the-international-society-of-aesthetic-plastic-surgery-releases-global-statistics-on-cosmetic-
procedures-300108852.html
10 http://www.people.com/people/package/article/0,,20998070_21001278,00.html

2016 State of Innovation stateofinnovation.com Cosmetics & Wellbeing 29


REUTERS/ISSEI KATO
2016 State of Innovation stateofinnovation.com Cosmetics & Wellbeing 30
FOOD, BEVERAGE & TOBACCO

If history repeats itself, can developing nations change health


outcomes and still be the latest frontier for
Tobacco and Beverage innovation?

2016 State of Innovation


REUTERS/ALESSIA stateofinnovation.com
PIERDOMENICO Food, Beverage & Tobacco 31
TOBACCO OUT-INNOVATES
FOOD AND BEVERAGES

Despite warnings that they’re bad for your health, cigarettes continue to dominate the world
stage in the category of Food, Beverage & Tobacco innovation, while also topping the charts for
companies with strong dividend payouts.

A recent Thomson Reuters Lipper Fund analysis stated that 2016 will be the year when consumer demand for “real” food
“CME Group, Dow Chemicals and Philip Morris are companies starts to seriously take effect as a decreased appetite for GMO
with strong fundamentals…Philip Morris is seeing good and non-natural foods gains momentum. GMO may be the
demand for cigarettes and enjoying healthy margins as its way to go to make certain staple crops have higher yields
business looks stronger than ever…If you are looking for and be more defect-resistant, however a growing number of
strong dividend payers, these companies may be worth consumers are demanding healthy food products with clear
a second look.” 11 labeling. Similarly, the Beverage market continues to move
away from sugary drinks toward healthy drinks and teas.
Where innovation really needs to happen, however, is in
the area of Food, for better ways to feed the world’s growing
population and produce healthy, non-processed alternatives
that don’t add to negative health effects.

“ We know that our food may contain a wide range of potentially hazardous
substances. But interesting solutions abound. The EFSA European Food
Consumption Database is using data in innovative ways to identify and help
reduce the risk of contaminated food, particularly among vulnerable populations.”
—Davide Arcella, Scientific Officer
European Food Safety Authority (9billionbowls.com)

11 http://lipperalpha.financial.thomsonreuters.com/2016/04/top-dividend-payers-include-cigarettes-chemicals-and-financials/

2016 State of Innovation stateofinnovation.com Food, Beverage & Tobacco 32


FOOD, BEVERAGE & TOBACCO OVERVIEW
2%

14%

% 30%
% Subsectors 2015 2014
Change
30% Meat 8,256 9,033 -9%
28% Brewing 7,662 6,479 18%
26% Bakery 7,267 6,841 6% 26%

14% Tobacco 3,923 4,215 -7%

2% Sugar&Starch 667 689 -3%


Source: Derwent World Patents Index 28%

Top 10 Global Innovators–Food, Beverage & Tobacco (2015)


Company Country # Inventions
China Tobacco Hubei Ind Corp China 1122
Qingdao Xiuxian Foods Co. China 165
Philip Morris US 121
University of Guangxi China 118
Inst Agro Food Science & Technology Chinese China 114
University of Jiangnan China 114
University of Zhejiang Ocean China 104
Hefei Bulaochuanqi Health Science & Technology China 87
Wuhu Hongyang Food China 72
Anhui Xianzhiyuan Food China 69
Source: Derwent World Patents Index

Top 10 Brewing Innovators–Asia (2011-2015)


Company Country # Inventions
University of Jiangnan China 217
Harbin Shanbao Wine Ind China 166
Luzhou Pingchuang Technology China 155
Korea Food Research Institute S Korea 109
Rural Development Administration Korea S Korea 89
Sapporo Breweries Japan 83
Guangming Dairy Ind China 82
Suntory Holdings Japan 81
Kirin Japan 80
Asahi Breweries Japan 73
Source: Derwent World Patents Index

2016 State of Innovation stateofinnovation.com Food, Beverage & Tobacco 33


Top 10 Brewing Innovators–Europe (2011–2015)
Company Country # Inventions
Novozymes Denmark 105
DSM Netherlands 89
Chr Hansen Denmark 45
Nestec Switzerland 40
Danone France 35
Krones Germany 32
IFP Energies Nouvelle France 21
GEA Brewery Systems Germany 18
Bayer Cropscience Germany 16
LeSaffre France 15
Source: Derwent World Patents Index

Top 10 Brewing Innovators–North America (2011–2015)


Company Country # Inventions
Danisco US 150
Butamax Advanced Biofuels US 31
Codexis US 22
Coskata US 22
BP North America US 21
University of California US 18
US Secretary of Agriculture US 18
Poet Res Inc US 16
Monsanto US 14
Mascoma US 13
Source: Derwent World Patents Index

Most Influential Scientific Research Institutions in Food Science & Technology


(2005 -2015)
Name Country # of Papers (WoS) Category Normalized Citation Impact
University of British Columbia Canada 431 1.93
Universiy of Lleida Spain 583 1.88
Polytechnic Institute of Braganca Portugal 316 1.79
University of Massachusetts System USA 824 1.73
Nanchang University China 415 1.66
Dresden University of Technology Germany 362 1.63
Rovira I Virgili Univeristy Spain 343 1.57
University of Melbourne Australia 306 1.55
University of Barcelona Spain 518 1.55
VTT Technical Research Centre of Finland Finland 314 1.54
Source: Web of Science

2016 State of Innovation stateofinnovation.com Food, Beverage & Tobacco 34


Summary

While food-related innovation can be found in the which it will need to find a way to sustain in the coming
Biotechnology sector where GMO crops and engineered- decades as earth’s population nears 10 billion people,
organism inventions are categorized, the Food, Beverage and smoking is still an accepted habit in this culture.
& Tobacco technology area covers inventions specific to the
manufacturing and composition of items outside of what is China Tobacco Hubei Industries Corp. is the most
genetically modified. prolific innovator across the entire sector, with 1,122
unique inventions, followed by Qingdao Xiuxian Foods Co.,
The sector remained predominantly flat over the last year, Philip Morris, University of Guangxi and Inst Agro Food
growing by just 1 percent or about 300 inventions more Science & Technology Chinese, all of which had 165 or fewer
than the prior period. The largest growth was in the area inventions for the same period. This mix of organizations
of Brewing, which bubbled over 18 percent to 7,662 unique gives a glimpse into their focus and priorities.
innovations last year, followed by Bakery, which puffed up
6 percent. Meat, Tobacco and Sugar & Starch all In terms of Brewing innovation, China again leads the
experienced declines. world, being home to the three most active Brewing
innovators globally: University of Jiangnan (217 inventions),
The top 10 most active innovators in this category are all Harbin Shinbao Wine Industries (166 inventions), and
from China except one: Philip Morris in the US. This makes Luzhou Pingchuang Technology (155 inventions).
logical sense since China has the world’s largest population,

“ The United States and China alone represent 68 percent of all of the patent
documents associated with crop breeding around the world. These two countries
are larger than the closest competing country by at least a factor of five.”
—Bob Stembridge, Senior IP Analyst, Thomson Reuters

2016 State of Innovation stateofinnovation.com Food, Beverage & Tobacco 35


REUTERS/DANIEL MUNOZ
2016 State of Innovation stateofinnovation.com Food, Beverage & Tobacco 36
HOME APPLIANCES

Will our appliances still need us when the


Internet of Things takes over?

2016 State of DUVIGNAU


REUTERS/REGIS Innovation stateofinnovation.com Home Appliances 37
TODAY’S CONNECTED HOME

The lyrics of a popular folk song for children read: “The head bone’s connected to the…neck bone;
the neck bone’s connected to the…back bone; the back bone’s connected to the…thigh bone…”
and so on. There could be a new take on this regarding our homes today. It might go something
like this: “The smart phone’s connected to the…coffee maker; the coffee maker’s connected to
the…refrigerator; the refrigerator’s connected to the…thermostat; the thermostat’s connected
to the…garage door…” and so on.

This isn’t such a far-fetched concept. Today’s connected “The IoT revolution will offer us opportunities and ease-of-use
homes are technologically linked in ways we couldn’t have we could have never imagined, but suddenly find ourselves
imagined a decade ago. And, it’s exactly this connectivity unable to live without…We need to give IoT time to thrive,
that’s driving much of the innovation in Home Appliances. and identify the markets for it that make sense. The Internet
The Internet of Things (IoT) has brought changes to the way of Things is really about finding new places that make
we live and what we expect. New technologies incorporated sense for the Internet. Let consumers decide what their next
into our homes, offices, clothing and appliances make them Internet will be,” said Shawn DuBravac, chief economist of the
smarter, more efficient and better managers of us. Consumer Technology Association (CTA) and author of Digital
Destiny: How the New Age of Data Will Transform the Way We
Live, Work, and Communicate.12

“BlackBerry began as a startup company that invented mobile computing. I can say
without reservation that the spirit of innovation, the drive to continue to improve,
is alive and well in this company. Every part of BlackBerry is driven by the desire to
create the most productive, secure and private solutions in the mobile marketplace—
that includes revolutionary smartphone features, software that makes critical
business and government communications more secure, and coming up with new
ways of enabling devices to communicate with one another through the Internet
of Things (IoT).”
—John Chen, Executive Chairman & CEO, BlackBerry

12 http://www.cio.com/article/3019286/ces/what-will-the-internet-of-things-be-when-it-grows-up.html

2016 State of Innovation stateofinnovation.com Home Appliances 38


HOME APPLIANCES OVERVIEW

7%

7%
%
% Subsectors 2015 2014
Change
9%
43% Kitchen 39,026 33,590 16%
34% Heating/Air Conditioning 30,552 24,316 26% 43%

9% Household Cleaning 8,173 6,718 22%

7% Human Hygiene 6,717 5,203 29%

7% Laundry 6,402 5,659 13%


Source: Derwent World Patents Index 34%

Top 10 Global Innovators–Home Appliances (2015)


Company Country # Inventions
Midea Group China 5,427
Zhuhai Gree Electric Appliances China 1,995
Haier Group China 1,315
Panasonic Japan 949
Mitsubishi Electric Japan 948
Samsung S Korea 736
BSH Hausgeräte Germany 697
LG S Korea 690
Hitachi Kucho System Japan 460
Daikin Kogyo Japan 446
Source: Derwent World Patents Index

Top 10 Kitchen Innovators–Asia (2011-2015)


Company Country # Inventions
Midea Group China 3,309
Panasonic Japan 3,102
Mitsubishi Electric Japan 2,348
LG S Korea 2,234
Haier Group China 1,649
Joyoung China 1,538
Hitachi Kucho Japan 1,188
Sharp Japan 916
Toshiba Japan 907
Zhuhai Gree Electric Appliances China 880
Source: Derwent World Patents Index

2016 State of Innovation stateofinnovation.com Home Appliances 39


Top 10 Kitchen Innovators–Europe (2011-2015)
Company Country # Inventions
BSH Hausgeräte Germany 2,905
SEB Sweden 389
Electrolux Sweden 320
Nestec Switzerland 320
Philips Netherlands 318
Arcelik Turkey 253
Liebherr Hausgeraete Germany 237
Miele & Cie Germany 234
Rational Germany 145
EGO Elektro-Geraetebau Germany 135
Source: Derwent World Patents Index

Top 10 Kitchen Innovators–North America (2011-2015)


Company Country # Inventions
Whirlpool US 696
General Electric US 376
Carrier US 220
Johnson Controls US 76
Trane Int. US 65
Conair US 64
Thermo King US 63
DuPont US 60
Kraft Foods US 53
Illinois Tool Works US 52
Source: Derwent World Patents Index

Most Prolific Scientific Research Institutions in Home Appliances (2005–2015)


Institution Country # of Papers (WoS)
University of Zaragoza Spain 113
University of California Berkeley US 63
National Cheng Kung University Taiwan 53
Chinese Academy of Sciences China 44
Tsinghua University China 43
Polytechnic University of Milan Italy 40
Waseda University Japan 36
University of Tokyo Japan 35
Tohoku University Japan 35
Kyoto University Japan 33
Source: Web of Science

2016 State of Innovation stateofinnovation.com Home Appliances 40


Summary
Home Appliances is cleaning house in terms of its ranking In the Kitchen subsector, again Asia dominates, with Midea
on the innovation-activity barometer. The industry Group (China) and Panasonic (Japan) being the most active
experienced 21 percent year-over-year growth, with all globally. The world’s third most active Kitchen innovator
subsectors seeing double-digit jumps. is BSH Hausgeräte (Germany), followed by Mitsubishi
Electronics Home Appliances (Japan) and LG Electronics
The most active subsector is Kitchens, however the largest (South Korea).
increase occurred in Human Hygiene, which was up 29
percent over the prior period. Human Hygiene items include Asia is also home to 70 percent of the world’s top 10 most
things such as a body scrub brush with a built-in soap prolific scientific-research institutions with a focus on home
dispenser, hair-styling devices and nail clippers, to appliances. Japan leads with four, followed by China with
name a few. two and Taiwan with one. But the most active in terms of
research-paper out by far is the University of Zaragoza in
Asia is the undisputed leader in Home Appliance Spain (113 papers) and the University of California Berkeley
innovation. All but one of the top 10 innovators reside there, (63 papers).
the lone wolf being BSH Hausgeräte, based in Germany.
China takes the top three spots with Midea Group, Zhuhai There is no shortage of videos that portray what the future
Gree Electric Appliances and Haier Group, respectively. home may look like. If they are any indication of what’s
to come, this sector is sure to continue seeing increases
in innovation as the world is technologically modernized.
June and Ward Cleaver would be astonished to see what a
difference 50-plus years can make.

“ Our objectives are to overcome scientific and technological barriers in order to


develop innovations that can be used by the industry to create wealth and jobs
and to promote the emergence of a sustainable energy mix. Our innovation model
is underpinned by dual know-how: strong knowledge of the market needs and a
scientific approach of the highest level. Beyond science, we take into account the
economic, societal and environmental constraints associated with the development
of any innovation.”
—Didier Houssin, Chairman & CEO, IFPEN (IFP Energie Nouvelles)

2016 State of Innovation stateofinnovation.com Home Appliances 41


2016 State of Innovation stateofinnovation.com Home Appliances 42
INFORMATION TECHNOLOGY

From the cloud to computers and blockchain,


this is the neural net of technology.

2016 State of Innovation stateofinnovation.com Information Technology 43


PUSHING THE BOUNDARIES OF WHAT
WE THINK IS POSSIBLE

The IoT is a major contributor to what’s driving the Information Technology (IT) boom with its
increased demand for software, sensors and chips to connect our homes, cars and gadgets to
the Internet. In fact, it’s predicted that there will be 22 billion IoT installed devices by 2018.13

Cloud-based technology is another advancement that’s also Add to these technological trends things such as
pushing IT boundaries. It’s expected that at least half of IT cognitive computing, artificial intelligence, virtual reality
spending will be cloud-related in the next two years, with it and blockchain, among many others, and it’s clear why IT is
reaching 60 percent of all IT infrastructure and 60 -70 percent the place to be. It’s the underpinning and connective tissue of
of all software, services and technology spending by 2020.14 so many technological advancements, making it (IT) the true
cornerstone of the Digital Age.

“ Information Technology (IT) is the true cornerstone of the Digital Age, and with the
world’s data estimated to increase 800% by 2020 driven by the Internet of Things
(IoT), major IT trends such as Cloud computing and Cognitive computing will
rapidly develop to provide the flexibility and intelligence required to store, analyze
and provide services based on this vast repository of human knowledge.”
—George Jack, Engineering Expert, Thomson Reuters

13 http://www.forbes.com/sites/sap/2015/11/05/idc-releases-top-ten-2016-it-market-predictions/#222cac383e6b
14 http://www.forbes.com/sites/sap/2015/11/05/idc-releases-top-ten-2016-it-market-predictions/#222cac383e6b

2016 State of Innovation stateofinnovation.com Information Technology 44


INFORMATION TECHNOLOGY OVERVIEW

3% 2% 1%
5%
%
% Subsectors 2015 2014
Change 7%

82% Computing 387,097 340,386 14%


7% Other Peripherals 33,148 29,550 12%
5% Printers 24,752 23,359 6%

3% Smart Media 13,523 13,494 0%

2% Screens 8,112 7,692 5%

1% Scanners 4,471 4,510 -1% 82%

Source: Derwent World Patents Index

Top 10 Global Innovators–Information Technology (2015)


Company Country # Inventions
State Grid Corp China China 7,479
Canon Japan 6,370
Samsung S Korea 5,792
IBM US 4,205
Ricoh Japan 3,539
Google US 3,164
Huawei China 2,799
Lenovo China 2,798
LG S Korea 2,521
Tencent Technology Shenzhen China 2,418
Source: Derwent World Patents Index

Top 10 Smart-Media Innovators–Asia (2011-2015)


Company Country # Inventions
Samsung S Korea 1,575
Toshiba Japan 646
State Grid Corp of China China 630
Toppan Printing Japan 557
ZTE China 369
Panasonic Japan 342
Dainippon Printing Japan 332
Sony Japan 324
NEC Japan 278
Hon Hai Precision Industry Co Taiwan 274
Source: Derwent World Patents Index

2016 State of Innovation stateofinnovation.com Information Technology 45


Top 10 Smart-Media Innovators–Europe (2011-2015)
Company Country # Inventions
Giesecke & Devrient Germany 252
Gemalto Netherlands 204
Siemens Germany 201
NXP Netherlands 171
Nokia Finland 127
Ericsson Sweden 115
STMicroelectronics Switzerland 110
Oberthur France 109
Merck Germany 94
Infineon Germany 88
Source: Derwent World Patents Index

Top 10 Smart-Media Innovators–North America (2011-2015)


Company Country # Inventions
Sandisk US 228
IBM US 225
Qualcomm US 225
Apple US 223
Broadcom US 185
Micron US 166
Intel US 153
Microsoft US 103
BlackBerry US 101
Google US 96
Source: Derwent World Patents Index

Most Influential Scientific-Research Institutions in Computer Science (2005–2015)


Institution Country # of Papers (WoS) Category Normalized Citation Impact
Technical University of Czestochowa Poland 362 4.25
Wellcome Trust Sanger Institute UK 392 4.25
European Molecular Biology Lab Germany 675 3.80
Stanford University US 5,107 2.77
California Institute of Technology US 1,976 2.76
Ecole Normale Superieure, Paris France 721 2.70
Massachusetts Institute of Technology US 6,287 2.67
University of California Berkeley US 4,804 2.60
University of California Los Angeles US 3,627 2.56
University of South Wales UK 339 2.53
Source: Web of Science

2016 State of Innovation stateofinnovation.com Information Technology 46


Summary
Information Technology is the engine behind much of the In the Smart Media subsector, Samsung is the clear
innovation happening across many sectors. That’s why frontrunner with more than twice as many unique
IT continues to dominate as the largest technology area inventions as its nearest competitor: Toshiba. Giesecke &
covered in the State of Innovation, as has been the case Devrient leads in Europe and Sandisk in the US, but with
since this publication’s inception, and comprises 31 percent much less overall activity than their Asian counterparts.
of the overall activity volume with nearly 430,000 unique
inventions just last year. Academic and scientific research in computer science has
a more global footprint, with Asian institutions interestingly
The companies leading the top 10 in the global IT pack are absent from the world’s top 10 in scholarly research. Poland
predominantly from Asia: China, Japan and South Korea, and the UK are home to the most impactful institutions:
with just two outsiders: IBM (US) and Google (US). The Technical University of Czestochowa and Wellcome Trust
world’s leading three innovators are State Grid Corp of Sanger Institute, respectively, however the Technical
China (China), Canon (Japan) and Samsung (South Korea). University of Czestochowa has slightly fewer overall papers,
Each of these leaders’ activity is significant, with thousands making them collectively more impactful than Wellcome’s.
of unique inventions annually.

Computing is by far the most active subsector, comprising


82 percent of IT’s overall activity. This includes inventions
to see through walls (Vayyar), etch 3-D printed logos into
almost any surface (Glowforge), charge smartphones
at stations (NRG-Go) and uniquely light objects to
photograph them in high detail.15

“ Mobility is a key societal value, especially in megacities where half of the total
population is concentrated. Everyone expects more connected and autonomous
cars, with a simpler man to machine interface. Driving assistance features will
reinforce safety and reduce CO2 emissions, through optimized ‘eco-driving,’ while
improving the driving experience: this is the new concept of “Intuitive Driving”
that Valeo has developed.”
—Jacques Aschenbroich, CEO, Valeo

15 http://www.computerworld.com/article/3021280/ces/looking-to-the-future-5-new-ideas-from-ces-2016.html#slide1

2016 State of Innovation stateofinnovation.com Information Technology 47


2016 State of Innovation
REUTERS/SCOTT AUDETTE stateofinnovation.com Information Technology 48
MEDICAL DEVICES

The support infrastructure of the healthcare industry, these varied


devices keep physicians and patients thriving and ticking.

2016 State of Innovation


REUTERS/DMITRY NEYMYROK stateofinnovation.com Medical Devices 49
PUMPING HARD TO KEEP US PUMPING

Medical devices are essential staples in every operating and hospital room. They’re the literal
sustenance of life for diabetics, dialysis patients and those who are oxygen dependent, among
many others. In life-threatening situations, they are silently behind the scenes ensuring
emergency technicians have the tools needed for the most successful outcome.

These syringes, tubes, tanks, vials and other apparatus are chronic medical devices, they’re essential. For the developing
the hardware of the medical and health industry, much like world, they play an important role in the transformation to a
semiconductors are the hardware of electronic gadgets. developed economy.
Humans, as a whole, literally can’t live without them in the
appropriate situations. Medical device companies have a unique opportunity to
collabovate and partner with technology and software
It may not be much of a surprise then that the Medical Device businesses to marry their data insights with new solutions
sector is alive and healthy. In developed nations, it’s a part and provide valuable views to physicians and patients alike.
of daily life for many. With aging populations and growing Luckily for all of us, the sector is pulsing.

“ A host of medical device companies, including frontrunner Medtronic, have filed


patents and are in the process of developing an artificial pancreas, with the first
system expected to be available for use by type 1 diabetics sometime in 2017.
This unique closed-loop system consists of an insulin pump, a continuous glucose
monitor placed under the user’s skin, and advanced control algorithm software
embedded in a smartphone that intuitively signals how much insulin the pump
should deliver to the patient. This system essentially takes the patient out of the
diabetes management equation via the automation of the insulin regulation and
injection process, which should greatly improve outcomes for these people.”
—Holland Johnson Executive Editor, Medical Device Daily

2016 State of Innovation stateofinnovation.com Medical Devices 50


MEDICAL DEVICES OVERVIEW

17%
%
% Subsectors 2015 2014
Change
33% Diagnosis, Surgery 45,112 36,929 22% 33%

Sterilizing, Syringes,
30% 41,528 31,898 30%
Electrotherapy
20%
Medical Aids,
20% 27,186 18,694 45%
Oral Administration
17% Dentistry, Bandages, Prosthesis 22,490 19,250 17%
Source: Derwent World Patents Index

30%
Top 10 Global Innovators–Medical Devices (2015)
Company Country # Inventions
Olympus Optical Japan 818
Siemens Germany 638
Toshiba Japan 627
Fourth Military Medical University China 623
Samsung S Korea 526
Terumo Japan 482
Philips Netherlands 479
Canon Japan 473
Medtronic US 362
Covidien US 358
Source: Derwent World Patents Index

Top 10 Diagnosis-Surgery Innovators–Asia (2011-2015)


Company Country # Inventions
Olympus Optical Japan 3,246
Fujifilm Japan 2,830
Toshiba Medical Japan 2,682
Canon Japan 1,862
Samsung S Korea 1,539
Terumo Japan 1,020
Hitachi Medical Japan 913
Hoya Japan 807
Konica Minolta Japan 796
Seiko Epson Japan 693
Source: Thomson Reuters Derwent World Patents Index

2016 State of Innovation stateofinnovation.com Medical Devices 51


Top 10 Diagnosis-Surgery Innovators–Europe (2011-2015)
Company Country # Inventions
Siemens Germany 2,850
Philips Netherlands 1,861
Warsaw Orthopedic Poland 400
Aesculap Germany 328
Smith & Nephew UK 305
Zeiss Meditec Germany 281
Biosense Webster Israel Israel 264
Storz GmbH & KG Karl Germany 264
Roche Diagnostics Switzerland 217
Biedermann Technologies Germany 150
Source: Derwent World Patents Index

Top 10 Diagnosis-Surgery Innovators–North America (2011-2015)


Company Country # Inventions
Covidien US 2,353
General Electric US 1,716
Boston Scientific SciMed US 1,125
Ethicon Endo-Surgery US 1,073
Medtronic US 1,056
Depuy Synthes US 769
St Jude Medical US 417
Cook Medical Technologies US 412
Intuitive Surgical Operations US 379
Abbott Diabetes Care US 368
Nellcor Puritan Bennett US 346
Source: Derwent World Patents Index

Most Prolific Scientific Research Institutions in Medical Devices (2005–2015)


Name Country # of Papers (WoS)
US FDA US 219
Harvard University US 190
University of Pennsylvania US 101
University of Michigan US 93
Stanford University US 90
Duke University US 88
University of Minnesota US 85
Massachusetts Institute of Technology US 80
Brigham and Women’s Hospital US 72
University of North Carolina US 71
Source: Web of Science

2016 State of Innovation stateofinnovation.com Medical Devices 52


Summary

Following the reported 6 percent year-over-year decline in non-Japanese company in that top 10. Germany is the clear
Medical Devices from the prior period, innovation in this leader in Europe, with 60 percent of the top 10 companies,
area got a shot in the arm to become the most active of and the US takes all of the top spots for North America,
all technology sectors covered. It had the largest year- with Covidien at the top followed by General Electric and
over-year increase, 27 percent, and all of its subsectors Boston Scientific.
had double-digit growth, with Medical Aids & Oral
Administration seeing the largest increase: 45 percent. Medtronic completed its acquisition of Covidien in 2015,
so their innovation activity for this period was reported
Japan is home to 40 percent of the world’s top 10 Medical separately. Their combined total output is more than 3,400
Device companies, including the world leader Olympus. inventions, however, making them the overall global leader
China and South Korea also have their hands in this sector, in Diagnosis, Surgery, even over Japan’s Olympus, with
with the Fourth Military Medical University and Samsung 3,246 unique inventions.
Electronics, respectively. Europe and the US also make
contributions to the global top 10, with two and three All of the top 10 most prolific medical device research
innovators each, respectively. institutions are from the US, with the FDA at the top
followed by Harvard and the University of Pennsylvania.
In the Diagnosis Surgery subsector, Japan has 90 percent It’s interesting that despite Japan’s leadership position in
of the top 10 innovators in Asia, demonstrating the nation’s innovation, it doesn’t rank in the top 10 of the most prolific
proclivity in this field. South Korea’s Samsung is the only scholarly research organizations globally.

“ For us, innovation isn’t just about creating exciting objects that catch the
imagination of our customers for one heady moment. Instead, it’s about perfecting
products, services and business models that help our customers to take care of
people and save lives, to live healthier and enjoy themselves, and to be part of a more
sustainable world. At Philips, Innovation is at the very core of our business strategy,
as well as our brand positioning and company’s mission: ‘At Philips we strive to make
the world healthier and more sustainable through innovation’.”
—Brian Hinman, Chief IP Officer, Philips

2016 State of Innovation stateofinnovation.com Medical Devices 53


2016 State
REUTERS/ALY of Innovation stateofinnovation.com
SONG Medical Devices 54
OIL & GAS

Fossil-fuel-based products emit harmful greenhouse gases.


Can we make the transition to environmentally
friendly alternatives to meet governmental goals?

2016 State of Innovation


REUTERS/WOLFGANG RATTAY stateofinnovation.com Oil & Gas 55
COP21 CREATES GLOBAL CHALLENGE FOR
ENERGY INNOVATORS

December 2015 will long be remembered as the month when the historic COP21 (Conference of
Parties) took place in Paris, where nearly 200 heads of state from around the world agreed to try
to slow global warming and overcome its negative effects.

Innovation is imperative in order to drive alternative ways a year earlier;16 Shell’s quarterly profit dropped by 70
to power the planet and reduce our dependence on fossil percent;17 and Total in France announced a 69 percent
fuels. It’s essential that we find more environmentally friendly decline,18 to name a few.
sources of energy without harmful greenhouse gas emissions.
Nevertheless, the sector continues to innovate. Some of the
Could Oil & Gas bellwethers hold the answer? innovation has been related to finding new ways to extract
energy from traditional sources, such as the process involved
Corporate quarterly-earning conference calls convey the in hydraulic fracturing, or ways to mitigate carbon emissions
toll of the state of today’s industry, with plunging prices and from existing oil-extraction methods. The big question on
decreasing demand. Exxon Mobil reported a 58 percent many analysts’ minds, however, is whether or not the large
decline in its 2015 third-quarter profit over the same period Oil & Gas players will be able to find sustainable solutions
to the COP21 challenge, via R&D investments or otherwise.

“ The rout in crude prices is snowballing into one of the biggest avalanches in the
history of corporate America, with 59 oil and gas companies now bankrupt…The
number of U.S. energy bankruptcies is closing in on the staggering 68 filings seen
during the depths of the telecom bust of 2002 and 2003…”
—Ernest Scheyder, Houston Energy Correspondent, Reuters News &
Terry Wade, Houston Bureau Chief, Reuters News
http://www.reuters.com/article/us-usa-shale-telecoms-idUSKCN0XV07V

16 http://www.nytimes.com/2016/02/03/business/energy-environment/oil-company-earnings.html?_r=0
17 http://oilprice.com/Energy/Energy-General/Top-Oil-Companies-Report-Dismal-Earnings.html
18 Ibid

2016 State of Innovation stateofinnovation.com Oil & Gas 56


OIL & GAS OVERVIEW
3% 1%

%
% Subsectors 2015 2014
Change
Exploration, Drilling, 32%
64% 18,086 15,589 16%
Production
32% Fuels and Other Products 9,224 8,459 9%
3% Transportation and Storage 864 658 31%
64%
1% Refining 241 183 32%
Source: Derwent World Patents Index

Top 10 Global Innovators–Oil & Gas (2015)


Company Country # Inventions
Sinopec China 1,991
Petrochina China 1,982
Halliburton US 940
China National Offshore Oil China 455
Schlumberger US 378
Baker Hughes US 288
PRAD Research & Development US 272
University of China Petroleum China 239
Toyota Japan 219
Tatneft Stock Russia 189
Source: Derwent World Patents Index

Top 10 Petroleum & Natural Gas Exploration Innovators–Asia (2011-2015)


Company Country # Inventions
Sinopec China 7,612
Petrochina China 7,245
China National Offshore Oil China 1,798
University of China Petroleum China 803
University of Southwest Petroleum China 675
Nippon Oil Japan 294
University of Northeast Petroleum China 251
Toyota Japan 232
Beijing Sany Heavy Machinery China 227
Daewoo Shipbuilding & Marine ENG CO S Korea 195
Source: Derwent World Patents Index

2016 State of Innovation stateofinnovation.com Oil & Gas 57


Top 10 Petroleum & Natural Gas Exploration Innovators–Europe (2011-2015)
Company Country # Inventions
Tatneft Stock Russia 903
Shell Oil Netherlands 666
Saudi Arabian Oil Co Saudi Arabia 468
IFP Energies Nouvelles France 371
BASF Germany 311
TOTAL SA France 198
BP UK 160
Statoil Petroleum Norway 125
Linde Germany 113
Welltec AS Denmark 113
Source: Derwent World Patents Index

Top 10 Petroleum & Natural Gas Exploration Innovators–North America (2011-2015)


Company Country # Inventions
Halliburton Energy Services US 2,848
Schlumberger Technology US 1,905
Baker Hughes US 1,452
PRAD Research & Development US 1,256
Exxon Mobil US 637
UOP US 619
Chevron US 435
National Oilwell Varco US 329
Weatherford/Lamb US 308
Smith Int US 223
Source: Derwent World Patents Index

Most Influential Scientific Research Institutions in Oil & Gas (2005-2015)


Name Country # of Papers (WoS) Category Normalized Citation Impact
Imperial College London UK 119 4.57
United States Department of Energy US 102 2.89
Stanford University US 191 2.65
University of Texas Austin US 339 2.09
Delft University of Technology Netherlands 108 1.93
Norwegian University of Science & Technology Norway 149 1.81
Tallinn University of Technology Estonia 170 1.72
Heriot Watt University UK 154 1.63
Texas A&M University US 338 1.52
University of Oklahoma US 176 1.50
Source: Web of Science

2016 State of Innovation stateofinnovation.com Oil & Gas 58


Summary
The sector’s innovation pace ignited beyond the prior Europe and the Middle East feature an eclectic mix in their
period, jumping up 14 percent overall, with Refining and top 10, comprising Russia’s Tatneft Stock in the top spot,
Transportation & Storage seeing the largest subsector followed by eight others from Europe and one from Saudi
jumps of 32 and 31 percent, respectively. Arabia. UK, France, Germany, the Netherlands, Norway and
Denmark comprise the European contingent. Halliburton
China leads the world’s innovation activity taking the top Energy Services is the leading US Oil & Gas innovator for
two spots globally. Sinopec and Petrochina rank first and Exploration, Drilling & Production, and is third globally
second, respectively. China National Offshore Oil is fifth. overall in volume for this category.
The US is the next most active region with Halliburton,
Schlumberger, Baker Hughes and PRAD Research & The Imperial College of London is the most influential
Development making the top 10 list. scholarly research institution in the Oil & Gas sector,
followed by the US Department of Energy and Stanford
In the subsector Exploration, Drilling & Production, China University. Imperial’s department of Earth Science and
again dominates, with 80 percent of the top 10 for Asia, Engineering has a Petroleum Engineering group that does
including the same three innovators as above securing the significant industry-funded research, which can be found
first three positions. Japan rounds out the remaining two in on its website: imperial.ac.uk/engineering/departments/
the top 10 with, interestingly, Toyota as part of the mix. earth-science/research/.

“ These days, global businesses and technology environments see their existing
businesses and technologies being replaced at alarming speeds by new ones
through the combination and convergence of diverse businesses and technologies.
In the energy industry where LSIS engages, Internet of Things, big data, and
innovation of manufacturing are emerging, ushering in a smart era of ICT
combination and convergence and a direct-current era that can change the
existing electric power paradigm.”
—Ja-Kyun Koo, Chairman & CEO, LSIS

2016 State of Innovation stateofinnovation.com Oil & Gas 59


2016 State ofMACGREGOR
REUTERS/LUKE Innovation stateofinnovation.com Oil & Gas 60
PHARMACEUTICALS

Do you know who makes your medication and where it’s from?
You might be surprised how much comes from Asia.

2016 State of Innovation stateofinnovation.com Pharmaceuticals 61


CHANGING DYNAMICS STEER INDUSTRY

The pharmaceutical industry continues to grow thanks to its branching into creative, new markets.
Proof can be seen in the seven drugs expected to launch this year that Thomson Reuters predicts
will achieve blockbuster sales status of more than $1 billion in revenue by 2020, with some
predicted to hit $2 billion during that period.

The current pharmaceutical-success trend is a result of a Collabovation is a prerequisite for future pharmaceutical
concoction featuring an increased focus on rare diseases, growth in order to meet the health and drug needs of a
ongoing development of more convenient Fixed Dose larger population, especially in developing nations, and to
Combination (FDC) regimens and the continuation of the ensure the longevity of an aging demographic as well. R&D
conflict between price versus access to medicines. These, models will increasingly shift to involve partnerships between
alongside new treatments involving bio-organisms, several pharmas and either their suppliers or partners, allowing each
new vaccines (such as for malaria and dengue fever) and party to focus on its respective area of expertise. Testing of
immune-therapies have given the sector a burst of adrenaline. “virtual beings” is also expected to expedite development and
trial cycles, bringing drugs to market faster and with
more successful outcomes.19

“ The relationship between drug prices and the costs of development is expected to
be a major focal point for drug companies, investors, regulators and politicians this
year. With the rise of global healthcare costs, the need to demonstrate meaningful
impact will be greater than ever for pharmaceutical companies. The 2016 drugs to
watch are likely to figure prominently in those discussions.”
—Richard Harrison, Chief Scientific Officer,
Thomson Reuters Intellectual Property & Science

19 http://www.pwc.com/gx/en/industries/pharmaceuticals-life-sciences/pharma-2020/pharma2020-virtual-rd-which-path-will-you-take.html

2016 State of Innovation stateofinnovation.com Pharmaceuticals 62


PHARMACEUTICALS OVERVIEW
3%1%
11%
%
% Subsectors 2015 2014
Change
63% Organics 88,116 85,679 3%
22% General 30,320 26,774 13%
22%
11% Heterocyclics 15,854 16,272 -3%

3% Inorganics 3,975 1,373 190%


63%
1% Steroids 1,036 1,075 -4%
Source: Derwent World Patents Index

Top 10 Global Innovators–Pharmaceuticals (2015)


Company Country # Inventions
Roche Switzerland 351
University of Jiangnan China 320
University of Zhejiang China 274
LG Household & Healthcare S Korea 270
Foshan Saiweisi Pharma Technology China 266
University of California US 235
Sanofi France 232
University of Shanghai Jiaotong China 225
CNRS France 223
University of Guangxi China 209
Source: Derwent World Patents Index

Top 10 Heterocyclics Innovators–Asia (2011-2015)


Company Country # Inventions
University of China Pharmaceuticals China 454
University of Nanjing China 312
Takeda Pharmaceuticals Japan 292
Shanghai Inst Pharma China 263
University of Zhejiang China 239
University of Shandong China 238
University of Fudan China 234
Foshan Saiweisi Pharma Technology China 229
Cadila Healthcare India 213
Hainan Weikang Pharma Qianshan China 212
Source: Derwent World Patents Index

2016 State of Innovation stateofinnovation.com Pharmaceuticals 63


Top 10 Heterocyclics Innovators–Europe (2011-2015)
Company Country # Inventions
Roche Switzerland 642
Novartis Switzerland 499
Bayer Germany 427
GlaxoSmithKline UK 382
Boehringer Ingelheim Germany 364
Sanofi France 349
Janssen Pharmaceuticals Belgium 244
CNRS France 188
Merck Germany 176
Astrazeneca UK 134
Source: Derwent World Patents Index

Top 10 Heterocyclics Innovators–North America (2011-2015)


Company Country # Inventions
Merck & Co. US 732
Bristol-Myers Squibb US 373
Abbvie US 361
Allergan US 282
Gilead Scientific US 228
Genentech US 200
Pfizer US 199
University of California US 195
Vertex Pharmaceuticals US 172
Teva Pharmaceuticals US US 123
Source: Derwent World Patents Index

Most Influential Scientific Research Institutions in Pharmaceuticals (2005–2015)


Name Country # of Papers (WoS) Category Normalized Citation Impact
Tianjin University China 325 4.97
Lundbeck Corporation Denmark 529 3.59
Gilead Sciences US 478 3.34
World Health Organization EU 316 2.53
University of Newcastle UK 450 2.37
University of the Chinese Academy of Sciences China 742 2.31
Howard Hughes Medical Institute US 477 2.28
Guy’s & St. Thomas’ NHS Foundation Trust UK 762 2.21
Massachusetts Institute of Technology US 953 2.17
Tsinghua University China 579 2.16
Source: Web of Science

2016 State of Innovation stateofinnovation.com Pharmaceuticals 64


Summary

Pharmaceuticals experienced 4 percent year-over-year In the subsector for Heterocyclics, China again dominates
growth, with the most significant increase occurring in the top ten list in Asia with 80 percent of the organizations
inorganics, which jumped up by 190 percent, from 1,373 in that area. Heterocyclics are classic compounds that have
to 3,975 unique inventions for the period. Inorganics include atoms of at least two different elements as part of their
all non-carbon-based chemical compounds, featuring an rings. Cadila Healthcare of India also makes the top 10
array of metallic compounds as well as those that global innovator list within this area.
are synthesized in a chemical plant or lab.
Merck, Roche and Novartis are the world’s three most
Globally, China is the world’s leading region for innovative organizations overall in Heterocyclic volume,
Pharmaceutical innovation with 50 percent of the top 10 surpassing even China’s leading organizations in their
pharmaceutical companies residing there: University of R&D activity. Contrary to Asia, nearly all of the top 10
Jiangnan, University of Zhejiang, Foshan Saiweisi Pharma organizations in Heterocyclics in Europe and North America
Technology, University of Shanghai Jiaotong and University are from the private, corporate sector.
of Guangxi. The collabovation between the public and
private sectors is also clear in this industry, as all of The most influential top 10 scientific research organizations
China’s representatives are from academia. in pharmaceuticals have balanced representation across
China, Europe and North America, with China’s Tianjin
University taking the top spot.

“ Innovation flourishes when you take away the fear to fail, encourage people to take
controlled risks and create a healthy mix of diverse skills, cultures and experiences
within your workforce. Last but certainly not least, we constantly remind ourselves
that the customers in our care, the physicians, veterinarians, farmers and
consumers, ultimately determine what the true innovations are.”
— Dr. Marijn Dekkers, CEO, Bayer AG

2016 State of Innovation stateofinnovation.com Pharmaceuticals 65


REUTERS/CHAIWAT SUBPRASOM
2016 State of Innovation stateofinnovation.com Pharmaceuticals 66
SEMICONDUCTORS

The lifeline of today’s technological devices,


semiconductors are the Digital Age organs that keep us
connected, informed, hopping...alive.

2016 State of Innovation stateofinnovation.com Semiconductors 67


ASIAN CONDUCTORS
LEAD IN THE SPACE

The industry for those little chips, sensors and circuits that are the hardworking internal organs of
today’s electronic devices is going through a period of transformation. On the one side is massive
consumer demand for gadgets to be better, faster and more intelligent. The automotive and
IoT trends mentioned earlier in this paper are examples of how technology is becoming more
connected and being applied in new ways.

The flip side is lower manufacturer expectations for While China may be earmarked as the epicenter of
profitability and the push for more environmentally friendly Semiconductor growth for the near future, the global
solutions to power our future. Semiconductors have an Semiconductor space is evolving, moving to the next stage of
important role to play, however it will take the next its lifecycle, and is ripe for creative inventors to apply them in
generation of innovation to bring them back to their heyday. new ways.

Intel recently announced plans to lay off 11 percent of its


workforce—up to 12,000 people.20 This comes on the tails
of other publicized layoffs from bellwethers like Samsung
Electronics, Marvell and others in the space.

“ Overall growth in the semiconductor space is slowing due to the slowdown in the
largest segment, which includes desktop PCs (personal computers), notebooks,
ultra-mobiles and tablets. The latest growth drivers, occupying smaller segments,
are now the mobile sector, automotive markets, sensors, light-emitting devices
and the advanced packaging industry. On the horizon, the next big growth driver
is the Internet of Things (IoT), and is expected to have a significant impact on the
advanced packaging. Meanwhile the Chinese government continues to invest
heavily in building its own semiconductor industry with the aim to catch up
technologically with the world’s leading firms by 2030. Will this one day
mean cheaper electronics worldwide and major advancements in innovation
as competition increases? Time and research/analysis will tell.”
—Jason Foster, Senior Semiconductor Analyst,
Quality Expert & Content Specialist, Thomson Reuters

20 http://www.investors.com/news/technology/elephant-intel-dances-but-12000-layoffs-could-signal-recession/

2016 State of Innovation stateofinnovation.com Semiconductors 68


SEMICONDUCTORS OVERVIEW

4%

%
% Subsectors 2015 2014
Change 27%
Semiconductor Materials
40% 54,907 56,827 -3%
and Processes 40%
Memories, Film and Hybrid
29% 40,920 35,220 16%
Circuits
27% Discrete Devices 37,771 38,571 -2%

4% Integrated Circuits 5,771 5,775 0%


Source: Derwent World Patents Index
29%

Top 10 Global Innovators–Semiconductors (2015)


Company Country # Inventions
Samsung S Korea 4,144
BOE Technology Group China 2,900
LG S Korea 2,884
Shenzen China Star Optoelectronics Tech China 1,701
Toshiba Japan 1,521
Taiwan Semiconductor Mfg Co Taiwan 1,424
Semiconductor Mfg. Int. Shanghai Corp China 1,405
IBM US 969
SK Hynix S Korea 873
Oceans King Lighting Science & Technology China 872
Source: Derwent World Patents Index

Top 10 Semiconductor Materials & Processes Innovators–Asia (2011–2015)


Company Country # Inventions
Samsung S Korea 8,492
LG S Korea 5,878
Toshiba Japan 5,194
Semiconductor Mfg Int Shanghai Corp China 4,953
Taiwan Semiconductor Mfg Co Taiwan 4,836
SK Hynix S Korea 3,929
Renesas Electronics Japan 3,323
Panasonic Japan 3,163
Tokyo Electron Japan 2,998
Sharp Japan 2,462
Source: Derwent World Patents Index

2016 State of Innovation stateofinnovation.com Semiconductors 69


Top 10 Semiconductor Materials & Processes Innovators–Europe (2011–2015)
Company Country # Inventions
Infineon Technologies Germany 1,508
Osram Opto Semiconductors Germany 1,085
STMicroelectronics Switzerland 1,011
Commissariat Energie Atomique France 644
ASML Netherlands Netherlands 614
Bosch Germany 608
Merck Germany 412
Zeiss Smt Germany 391
Soitec France 285
Fraunhofer Ges Foerderung Angewandten EV Germany 280
Source: Derwent World Patents Index

Top 10 Semiconductor Materials & Processes Innovators–North America (2011-2015)


Company Country # Inventions
IBM US 5,307
Applied Materials US 1,855
Micron Technology US 1,629
GlobalFoundries US 1,057
Texas Instruments US 1,015
Intel US 881
Freescale Semiconductor US 844
Ase Group US 615
Advanced Micro Devices US 587
Intermolecular US 527
Source: Derwent World Patents Index

Most Prolific Scientific Research Institutions in Semiconductors (2005–2015)


Name Country # of Papers (WoS)
Chinese Academy of Sciences China 7,121
Russian Academy of Sciences Russia 3,566
University of Tokyo Japan 2,092
CNRS France 1,956
Tohoku University Japan 1,700
Osaka University Japan 1,695
University of California Berkeley USA 1,684
Nanyang Technological University Singapore 1,624
National Chiao Tung University Taiwan 1,504
Tokyo Institute of Technology Japan 1,334
Source: Web of Science

2016 State of Innovation stateofinnovation.com Semiconductors 70


Summary

Semiconductors hit a short circuit in the period ending Germany is the European leader in the Semiconductor
December 31, 2014 and showed a decline for the first time Materials & Processes subsector with 60 percent of the
in a number of years. Nevertheless, its path has been organizations in the world’s top 10. However, even with
somewhat corrected as it saw a 3 percent year-over-year Infineon at the top with 1,508 unique inventions over the
increase in activity, with Memories, Films & Hybrid Circuits five years, Samsung still comes out on top in terms of its
jumping 16 percent, the most of any subsector. The largest output with 463 percent more activity than Infineon. Even
segment: Semiconductor Materials and Processes, however, Japan’s Sharp, ranked tenth overall in Asia, is 63 percent
declined by 3 percent over the period. more active than the industry leader in Europe.

Asia continues to lead in the overall Semiconductor IBM takes the top US spot in this sub-category with 5,307
landscape, with Samsung Electronics taking the top unique inventions over the five years, but that is still 40
position and logging over 4,000 unique inventions in just percent fewer than Samsung.
one year. LG and SK Hynix (both from South Korea) also
rank in the top 10 overall. China, Japan and Taiwan all also In the scholarly research realm, Asia again leads with 70
place in the world’s top 10, with China taking four of the 10 percent of the top 10. China, Russia and Japan take the
slots, compared to just one each by Japan and Taiwan. IBM, top three spots globally. The EU and the US each have one
which previously held the number one position in this sector representative institution on the list of the most prolific
globally, is now eighth. Samsung has 328 percent more semiconductor research organizations.
inventions annually than IBM. Europe does not even place
in the top 10. Asia is the clear frontrunner in Semiconductor innovation
activity. Given the volume generated from that continent,
Samsung also dominates the subsector category for it’s evident that the region will be a force to reckon with and
Semiconductor Materials & Processes, with 45 percent the companies on this list are paving the way. The question
more volume than its nearest competitor, LG. Japan fares now becomes: how do these organizations morph to
well with 50 percent of the top innovators in this subsector. address the next stage of electronic and renewable needs.

“ Marvell has a rich history of leadership in semiconductor innovation, and


innovation remains one of the core values of our company. Innovation means many
things to Marvell but at the heart of it, we continue to have a steadfast focus on
advancing the global semiconductor industry with cutting-edge technologies and
solutions. In collaboration with our service provider and OEM customers, we are
dedicated to helping them bring new electronic systems and devices to market that
ultimately improve the lives of consumers around the world.”
—Dr. Zining Wu, Chief Technology Officer, Marvell Technology Group

2016 State of Innovation stateofinnovation.com Semiconductors 71


2016 State of Innovation stateofinnovation.com Semiconductors 72
TELECOMMUNICATIONS

There’s a swirling convergence of Telecoms activity,


from 5G to IoT and NFC.
OMG–let’s c if u r able 2 keep up–LOL.

REUTERS/DANIEL
2016 MUNOZ stateofinnovation.com
State of Innovation Telecommunications 73
TELECOMS TRIFECTA IS BASIS
FOR WHAT’S TO COME

The Telecommunications space is yet another that’s integral to the IoT phenomenon, providing
the network connectivity, equipment and devices essential for it to function. Collabovation
also plays a key role in the success of the sector, integrating Telecoms expertise with that of
automotive, appliance, fitness, wellbeing and other categories so partners on each side of the
equation can focus on what they respectively do best and leverage one another’s strengths.

The rub in all this is bandwidth. It’s currently somewhat The sky’s truly the limit when it comes to Telecoms, and that
limited and in order for Telecoms to really take off, more limit can and will be pushed as IoT becomes more pervasive,
spectrum is needed. The sector is being hit by a trifecta of customers demand fast and better accessibility, and new
sorts involving increased usage and demand for storage, technologies break old barriers. IoT, 5G, streaming services,
decreasing rates/pricing and the lack of a far-reaching the expansion of wearables and the shift to software-based
spectrum infrastructure. However, spectrum auctions and networking solutions will shape the future of Telecoms to
5G-technology development are poised to change this in the come. There’s ample growth opportunity and this is definitely
not-too-distant future. a space to pay attention to.

“ Since the dawn of telecommunications, Ericsson has put enormous time and
effort into collaborating with others to set the open standards that make global
communications and connections possible, with a firm belief that interoperability
and enabling end-to-end performance is key to leading innovation in the
information and telecom industry. To continue to advance technology, patents
play an active role through standardization and licensing and with one of the
strongest patent portfolios in mobile communications, Ericsson is a key driver
of open innovation. Without this open innovation, many of the advances in
mobile communications that we have come to rely on simply would not have
been possible.”
—Kasim Alfalahi, Senior Vice President & Chief Intellectual Property Officer, Ericsson

2016 State of Innovation stateofinnovation.com Telecommunications 74


TELECOMMUNICATIONS OVERVIEW
%
% Subsectors 2015 2014
Change 2% 2%
6%
26% Mobile Telephony 74,493 77,477 -4%
25% Data Transmission Networks 71,623 69,614 3% 9%
26%
Telephone Subscriber
21% 60,054 64,760 -7%
Equipment
Digital Information 9%
9% 25,797 27,053 -5%
Transmission
9% Telemetry & Telecontrol 25,417 18,437 38%
6% Multiplex & Multiple Access 15,633 16,256 -4%
2% Telephone Communications 6,855 7,003 -2% 21%
25%
2% Telephone Exchange Systems 5,610 5,954 -6%
Source: Derwent World Patents Index

Top 10 Global Innovators–Telecommunications (2015)


Company Country # Inventions
Samsung S Korea 4,132
Huawei China 3,496
LG S Korea 2,795
State Grid Corp China China 2,585
ZTE Corp China 1,960
Qualcomm US 1,841
Ericsson Sweden 1,424
Sony Japan 1,129
NTT Japan 1,129
Fujitsu Japan 1,087
Source: Derwent World Patents Index

Top 10 Mobile Telephony Innovators–Asia (2011–2015)


Company Country # Inventions
Samsung S Korea 12,713
LG S Korea 8,654
Sony Japan 5,095
Sharp Japan 4,627
Panasonic Japan 4,568
Huawei China 4,131
ZTE China 3,998
NEC Japan 3,786
Kyocera Japan 3,661
Fujitsu Japan 3,209
Source: Derwent World Patents Index
2016 State of Innovation stateofinnovation.com Telecommunications 75
Top 10 Mobile Telephony Innovators–Europe (2011–2015)
Company Country # Inventions
Ericsson Sweden 3,873
Nokia Finland 2,918
Alcatel Lucent (Nokia) France 1,628
Nokia Siemens Finland 733
Sony Ericsson Sweden/Japan 651
Bosch Germany 552
STMicroelectronics Switzerland 471
Orange France 341
Vodafone UK 314
Infineon Technologies German 298
Source: Derwent World Patents Index

Top 10 Mobile Telephony Innovators–North America (2011–2015)


Company Country # Inventions
Qualcomm US 6,534
Apple US 3,576
BlackBerry Canada 2,933
Intel US 2,825
Microsoft US 2,721
Google US 2,571
IBM US 2,083
AT&T US 1,735
Broadcom US 1,590
Motorola US 1,266
Source: Derwent World Patents Index

Most Impactful Research Institutions in Telecommunications (2005–2015)


Name Country # of Papers (WoS) Category Normalized Citation Impact
Rice University US 323 4.68
University of California Berkeley US 792 3.25
University of Texas Austin US 1,130 2.85
New York University US 432 2.77
Swiss Federal Institute of Technology Zurich Switzerland 723 2.76
Carnegie Mellon University US 762 2.70
State University of New York Stony Brook US 339 2.67
Illinois Institute of Technology US 530 2.59
Princeton University US 650 2.53
Microsoft US 700 2.35
Source: Web of Science

2016 State of Innovation stateofinnovation.com Telecommunications 76


Summary

Telecommunications was up 3 percent year-over-year, Samsung truly dominates in Mobile Telephony with 228
despite three-quarters of its subsectors declining slightly percent more activity than the nearest European competitor
in activity from the last period. The subsector Telemetry (Ericsson) and 95 percent more activity than the nearest US
& Telecontrol, which covers measuring, transmitting and competitor (Qualcomm).
receiving apparatus, experienced a whopping 38 percent
jump from 18,437 unique inventions at year-end 2014 to The US leads with 90 percent of the most impactful
25,417 unique inventions at the close of 2015. All the other Telecommunications scholarly research organizations,
subsectors declined between 2–7 percent except for Data the top three of which are Rice University, University of
Transmission Networks, which was up 3 percent. California Berkeley and University of Texas Austin. The
only non-US institution in the top 10 is Switzerland’s
Like in the Semiconductor sector, Asian companies lead Federal Institute of Technology Zurich. It’s worth noting
the top 10 list in Telecommunications innovation with 80 that despite the fact that Asia leads in having the most top
percent of the representation. Samsung (South Korea) takes innovators in Telecommunications, the leading scholarly
the most innovative spot, followed by Huawei (China) and research organizations do not hail from there, but rather
LG (South Korea). In addition to the two companies from primarily come from the US. Microsoft is the only corporate
South Korea and three from China, there are three Japanese organization to make it to the list of most impactful
organizations and one each from Sweden and the US in the Telecommunications organizations.
leading 10.

The same three Asian countries comprise the top 10 in the


Mobile Telephony subsector, with Samsung, LG and Sony
(Japan) taking the top three spots. In Europe, Ericsson,
Nokia (Finland) and Alcatel Lucent/Nokia (France) are
the three regional innovators, while Qualcomm, Apple
and BlackBerry (Canada) are the top three in North
America, the former two both from the US.

“ The Telecommunications space is evolving at warp speed. Clients want faster


connectivity. Increased security. Lighter weight gadgets. Global access to the
Internet and their content. And so on. It’s the backbone supporting many other
industries and market opportunities. 5G is the next frontier to conquer, which will
drive an entirely new wave of advancements. It’s an exciting time to be in the space
and paving the way for future generations.”
—Bob Schukai, Head of Applied Innovation, Thomson Reuters

2016 State of Innovation stateofinnovation.com Telecommunications 77


2016 State of Innovation stateofinnovation.com Telecommunications 78
“ We can never rest, never let ourselves get comfortable. The world is constantly
changing, and those that don’t adapt don’t stay on top for long. That really raises the
bar on our teams, and it drives us to think differently about how we bring innovation
to life in our markets, or in other words, how we commercialize it.”
—John Tracy, Chief Technology Officer, Boeing

2016 State of Innovation


REUTERS/CARLO ALLEGRI stateofinnovation.com Conclusion 79
SOLUTIONS FOR INNOVATION SUCCESS

Derwent Patents Citation Index Web of Science


For identifying possible partners, threats and ways to For tracing the development of an area of study and
evolve a technology area identifying top authors, institutions and publishers while
following the citation trail
Derwent Patents Citation Index (DPCI) is a value-added
citation database with both patent and scholarly literature The Web of Science is the world’s most trusted citation
citations. These trace historical references on which an index covering leading scholarly literature. It is the gold
invention is built, as well as an invention’s impact and future standard for research discovery and analytics, including
technologies that advance it. the world’s founding scientific citation database, covering
interdisciplinary fields such as the arts, humanities, sciences,
Updated weekly, there are more than 11 million patent and social sciences.
families and unique inventions that have been editorially
enhanced for following forward and backward citations. With The Web of Science platform is the search and discovery
this insight, users can identify potential licensing partners, choice for 7,000+ academic and research institutions,
competitive threats and ways to evolve core intangible assets. national governments, funding organizations and publishing
organizations in 100+ countries worldwide.
Within Thomson Innovation, DPCI is combined with the
Derwent World Patents Index (DWPI) to provide the widest
perspective of an invention and its impact and influence. Thomson Innovation
For turning research results into actionable intelligence
and collaborating across the innovation process
Derwent World Patents Index Thomson Innovation is the industry’s leading intellectual
For validity and infringement insight, unearthing existing property intelligence and collaboration platform for global
prior art, identifying white space and performing competitive- research and analysis. It incorporates patents, scholarly
landscape research literature and news information, alongside robust reporting,
Derwent World Patents Index (DWPI) is the world’s most visualization and work-file management tools, making it the
trusted and authoritative source of global patent information, most comprehensive patent workflow solution available.
covering 50 patent-issuing authorities. Bibliographic
Featuring data from around the world, including the coveted
patent information is translated into English and editorially
DWPI patent collection, Web of Science content and Reuters
enhanced to bring clarity to a patent’s true intentions.
news information, Thomson Innovation is a one-stop solution
A team comprising hundreds of editors, most with advanced for research and analysis.
degrees in their areas of specialization, incorporate value-
added insight alongside original patent content to accurately
understand the scope of an invention.

The world’s first and only such patent-search resource, with


over 50 years of longevity and trusted by nearly 40 of the
world’s patent offices, DWPI is a unique and unparalled
resource for patent research.

2016 State of Innovation stateofinnovation.com Conclusion 80


Methodology & Reprints
Data in this report was compiled using Derwent World Patents Index®, the
world’s most trusted and authoritative collection of editorially enhanced patent
information for more than 50 years; and Web of Science, the gold standard for
research discovery and analytics, including the world’s founding scientific citation
database, covering interdisciplinary fields such as the arts, humanities, sciences,
and social sciences.
Special thanks to our partners at STN for their assistance in providing access to
DWPI on STN for work done to determine the top assignees in each technology area.

Analysis was conducted by the Thomson Reuters PR & Thought Leadership team,
providers of expert insight and analysis for corporations, law firms and governments
around the world.

Report author: Laura Gaze, Thomson Reuters


Patent researcher: Bob Stembridge, Thomson Reuters
Scientific literature researcher: Christopher King

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