Documente Academic
Documente Profesional
Documente Cultură
Muhammad Sajid
Email: muhammaddrsajid@yahoo.com
Objectives
By the end of this lecture Students of 2nd Year BDS
will be able to know;
Define Entameoba Histolytica
Discuss Morphology of EH
Explain Life cycle of EH
Describe Pathogenicity of EH
Discuss Transmission and Treatment of
EH
Entamoeba Histolytica
Dormant/resistant
stage
Spherical
1-4 nuclei, (4 in
mature cysts)
Bluntly rounded
chromatoidal bars
Cyst:10-20 μm
Entamoeba histolytica Cysts
Entamoeba histolytica Cysts
Life cycle
Entamoeba histolytica Life
Cycle
• CYST: ingested with fecal
contaminated food or water.
Contamination
of foodstuffs Use of human
by flies, and Transmis feces (night
possibly sion soil) for soil
cockroaches fertilizer
Food or drink
contaminated
with feces
containing
the E.his. cyst
Pathogenicity mechanisms
E. histolytica has surface enzymes that can digest
epithelial cells and therefore hydrolyze host
tissues and cause pathology.
Macroscopic
Microscopic
RBC In clumps, redish yellow in Discrete, bright red in col
colour
Hepatomegally
Microscopic identification
This can be accomplished using: