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MULTIPLE SCLEROSIS
Avery Long
Description of pathology
Multiple Sclerosis mostly referred to as MS. MS can be dissected apart and essentially means many
scar tissues. Multiple means many and sclerosis means scar tissue. MS is an autoimmune disease
that primarily affects the central nervous system. The central nervous system consists of the
brain, spinal cord and optic nerves(2). Just about everything humans do is dependent on how
well the central nervous system functions, from movement of the muscles to though process
disease in which the immune system attacks the protective covering of nerves.
The brain and spinal cord includes billions of nerve cells called neurons and glial cells that help
navigate emotions, movement, behavior, touch, and balance (3). Essentially motor and sensory
cellular networking to decipher sensory information and to use motor skills in response to
sensory information. The central nervous system (CNS) is composed of large numbers of
excitable nerve cells and their processes, called neurons, which are supported by tissue called
neuroglia (2). A neuron is made up of a cell body (or soma) with branch-like dendrites (signal
receivers) and a projection called an axon, which conduct the nerve signal to and from the
neuron(book). Myelin wraps around the axon to make signals fire faster in some of these cells.
Much of the CNS uses axons wrapped in myelin. At the other end of the axon, the axon terminals
Per Martini & Bartholomew, the CNS integrates and coordinates sensory processing and motor
transmission throughout the body (2). The CNS also helps process memories, intelligence, and
your emotions (3). The spinal cord serves as a conduit for electrical signals between the brain
and the rest of the body. This also controls simple musculoskeletal reflexes without input from
the brain (3). The brain is responsible for integrating most sensory information and coordinating
body function, both consciously and unconsciously. Complex functions such as thinking and
feeling as well as regulation of homeostasis are attributable to various parts of the brain (3).
Mechanism of Pathophysiology
MS is a serious and life-altering disease and can affect patients mentally, physically and
emotionally. The body’s immune system mistakes the myelinated axon neurons in the CNS as a
foreign pathogen and causes it to attack. This then leads to the body destroying the myelin and
the axon in variable degrees. Without myelin these signals are not able to travel to the rest of the
body. MS also produces significant physical disability and emotional stress (6). MS interferes
with the electrical signals between the brain, spinal cord, and other parts of the body resulting the
brain not being able to fire signals throughout the body properly (6). If the brain is unable to send
signals through the body different your body will be compromised in multiple ways. Each time
MS eats at the myelinated axon scientist believe oligodendrocytes then try and repair itself which
results in scar tissue. MS then returns and attack again causing more and more scar tissue, which
causes more physical problems such as muscle spasms, blindness, and immobility (6). According
to WebMD there are four several types of MS, Relapsing-Remitting MS (RRMS), which is the
most common form of multiple sclerosis. People with RRMS have relapse periods, flare-ups or
exacerbations, when new symptoms appear (1). The next form is Secondary-Progressive MS
(SPMS), in which symptoms worsen more steadily over time, with or without the occurrence of
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not common and is characterized by slowly worsening symptoms from the beginning, with no
steadily worsening disease state from the beginning, with acute relapses but no remissions, with
Prevention
According to WebMD, there are no known ways to prevent Multiple Sclerosis. As with any
disease, diet and things such as not smoking can improve odds. These things also help to keep a
Treatment
WebMD people with relapsing-remitting MS and secondary progressive MS, treatment with
medicine may reduce the frequency of relapses and delay disability (6). Some different home
remedies help slow progression such as eating a balanced diet, staying active, and staying cool.
Care Plan
According to APRN Nancee Spillman the goal of treatment for multiple sclerosis patient is to
prevent depression. The need to shorten exacerbations and relieve neurologic deficits so that the
patient can resume a normal lifestyle. Help keep the MS patient active, and remain positive can
Conclusion
Multiple sclerosis (MS) is an inflammatory, chronic, degenerative disorder that affects nerves in
the brain and spinal cord. Myelin, the fatty substance that surrounds and insulates nerves and
facilitates the conduction of nerve impulses is the initial target of MS destruction. Signals from
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the brain to other cells or organs cannot properly function with damaged axons which cause
different disabilities. Although there is no cure for MS, there are numerous ways to help patients
maintain a comfortable lifestyle, such as: balanced diet, plenty of exercise, keeping cool. Having
open relationships with medical professionals, family, and friends also help cope with MS.
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References
Hooper K. Managing Progressive MS. New York, NY: National Multiple Sclerosis Society;
2011.
Martini, F.H. and Bartholomew, E.F. (2017). Essentials of Anatomy and Physiology, 7th edition.
PowerPoint Lecture Slides prepared by Betsy C. Brantley & Valencia College The Nervous
https://mssociety.ca/images/book/ms-the-facts-you-need.pdf
https://www.nationalmssociety.org
https://www.webmd.com/multiple-sclerosis/ms-treatment