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June 24, 2016

Av. Republica do Chile 230 – 3º andar
Centro - CEP: 20.031-170
Rio de Janeiro/RJ, Brazil
Telephone: +55 21-2102-4212
Fax: +55 21-2524-3344

Re: New Patent Application in Brazil

Your ref: 165.278-8
Our ref: MJ13031BR Applicant’s ref: 2014473 004
Filing Deadline: July 15, 2016

Dear Sir,
We would ask you to handle the Brazilian phase entry for PCT Patent Application No.
PCT/JP2014/006426 (International Filing Date: December 24, 2014, Priority Date:
March 17, 2014, published under WO 2015/140863 A1) on or before July 15, 2016.

1. Enclosed Documents
Please find herewith the following documents:
-International application form (PCT/RO/101) filed on the international filing date;
-English translation of description, claims, abstract and drawings as originally filed on
the international filing date; and
-A copy of WO 2015/140863 A1 including International Search Report in English.

We would ask you to prepare the necessary translations of the specification, claims,
drawings, and abstract, and file them before the Brazilian Patent Office.
2. Applicant, Inventor and Priority
Please see the information regarding applicant, inventors, and priority shown in the
enclosed international application form.

3. Substantive Examination Fee

Please pay a substantive examination fee at the time of filing or as soon as the formal
requirements of this case are met.

We look forward to working with you during the prosecution of this case. Should you
have any question please do not hesitate to contact us.
Kindly acknowledge the safe receipt of this instruction letter and enclosed documents.

Sincerely yours,

Miyuki HORIKAWA (Ms.)

Patent Attorney
Oba & Associates
KM Building 8th Floor
1-4-3, Iwamoto-cho, Chiyoda-ku, TOKYO 101-0032 JAPAN
TEL: +81-3-5821-2720 FAX: +81-3-5821-2721