Documente Academic
Documente Profesional
Documente Cultură
Based Nucleic
Acid Amplification Test
(CBNAAT)
Dr.M.P. Samrat Abhishek
M.B.B.S.,FICM
District TB Control
Born Robert Heinrich
Herman Koch
11 December 1843
Clausthal,
Kingdom of Hanover
Died 27 May
1910 (aged 66)
Baden-Baden,
Grand Duchy of Baden
Nationality German
Fields Microbiology
INCIDENCE OF TB IN INDIA
•Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis and, less
commonly, by other organisms of the ‘tuberculosis complex’. It is estimated that 3 million
people die from TB each year—the majority of them in developing countries.
• The annual incidence of New cases of all forms of TB (pulmonary and extra-pulmonary)
worldwide is estimated to be approximately 8 million, of which about 95% occur in
developing countries. Many TB cases in developing countries remain
undiscovered. Of the discovered smear-positive cases, less than half complete
treatment.
•The number of persons infected with the tuberculosis bacillus is estimated to be 1.7
billion, of which 1.3 billion live in developing countries. In India, more than 40% of adults
are infected with TB, and approximately 1.5 million cases are put on treatment every
year. An estimated 5 lakh deaths from TB occur every year.
o Tuberculosis is one of the deadliest public health
threats today, but there remains a lack of effective
diagnostic tools.
o untreated tb patients remain a source of infection for
other members of community & results in
considerable morbidity & mortality , especially in
PLHIV group.
Screening methods for tuberculosis:
•Pleural fluid is a suboptimal sample for the bacterial confirmation of pleural TB, using
any method. A pleural biopsy is the preferred sample.
•These recommendations do not apply to stool, urine or blood, given the lack of
data on the utility of Xpert MTB/RIF on these specimens.
CBNAAT SUSPECTS CRITERIA:
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