Glioblastoma

By Ms. Cahhal
What is Glioblastoma?

● Type of brain cancer

● Very aggressive
● Malignant tumor
● Type of astrocytoma
● Tumor makes its own blood supply

https://cdn1.medicalnewstoday.com/content/images/articles/31
8/318139/diagram-of-frontal-lobe-of-the-brain.jpg
 Brain Tumors Grades
● Grade One:
○ Slowly growing
○ Rarely spreads to new tissues
○ Can be completely removed
● Grade two:
○ Grows slowly
○ May spread to new tissues
● Grade Three
○ Grows quickly
○ Likely to spread
○ Tumor cells look very different than normal cells
● Grade Four: https://www.prostate.org.au/media/436864/cancer-cells-on-the
-gleason-grade-scale.jpg
○ Grows an spreeds quickly
○ Tumor cells don’t look like normal cells
 Glioblastoma: Grade Four Tumor

● Grade four tumors are also called glioblastoma

● Spread quickly
● Cells divide quickly

https://images.agoramedia.com/everydayhealth/gcms/How-Do
-Doctors-Grade-the-Severity-of-a-Glioblastoma-RM-722x406.j
pg

https://www.verywellhealth.com/thmb/xnYC1DVmfPtwj
 Where?

● Anywhere, but typically:

○ The cerebrum
○ Specifically the frontal and temporal lobes

https://web.stanford.edu/dept/radiology/radiologysite/images/M
ed%20students%2024,%20Neuro,Brain/Neuro,%20glioblasto
ma%20(1).png

https://cdn.jamanetwork.com/ama/content_public/journal/neur/
Symptoms

● Depends on where it is
● Constant headaches
● Seizures
● Changes in mood (frontal lobe)
● Trouble speaking (temporal lobe)

https://encrypted-tbn0.gstatic.com/images?q=tbn:ANd9GcRni
https://3c1703fe8d.site.internapcdn.net/newman/gfx/news/hire
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 http://www.eastsiderad.com/wp-content/uploads/2016/09/head
neck-cancer.jpg

Risk Factors
https://blogs.biomedcentral.com/on-medicine/wp-content/uploa
ds/sites/6/2018/12/HNC-blog-featured-image-620x342.jpg

● (Small portion) genetics

● Usually randomly
● Ionizing radiation to the head or neck
● Decreased risk for people with allergies
 https://www.gannett-cdn.com/-mm-/35958b344c27edbb5abafb
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Diagnosis and Treatment

● MRI or CT scan
● Treatment typically is:
○ Surgery
○ Chemotherapy/radiation
○ Electric field therapy
○ Palliative care

https://ichef.bbci.co.uk/news/660/cpsprodpb/C8AC/production/
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Survival Rates

● One year: 40.2%

● Two years: 17.4%
● Five years: 5.6%
● Depends on a lot of factors!
● Affects 2-3 out of every 100,000 people

https://images-na.ssl-images-amazon.com/images/I/41OweQll
0BL.jpg
Works Cited

All pictures from Google and sited on slides

https://www.webmd.com/cancer/brain-cancer/what-is-glioblastoma#2

https://www.youtube.com/watch?v=8d0B5R3HLFY

https://www.cancercenter.com/cancer-types/brain-cancer/grades

https://www.abta.org/tumor_types/glioblastoma-gbm/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681990/