Carrots may have a profound and positive effect in reduced risk, progression and treatment of prostate

cancer, some scientists suggested.Prostate cancer is a condition characterized by cell growth disorderly
and uncontrollably in prostate tissue. At the later stage, the cancerous cells may infect other healthy tissue
and organ a distance away from the original site.Carrot, a root vegetable with orange color is a sub spices
of Daucus carota, belongings to the family Apiaceae, native to Asian and Europe.

Nutritional Benefits

. Carbohydrates!. "ugars#. $ibre%. $at&. Protein'. (itamin A). *hiamine +(ittamin - . /iboflavin
+(ittamin !-0. 1iacin +(ittamin #- 2. (itamin ' . $olate +(ittamin 0- !. (itamin C #. (itamin 3
%. Calcium &. 4ron '. 5agnesium ). 5olybdenum . Phosphorus 0. Potassium!2. "odium4n the
study to verify the effect of carrots in risk of prostate cancer by reviewing publication of literature in
August !2 # of Pub5ed, E5 A"E, "copus, 6eb of "cience, the Cochrane register, and the Chinese
1ational

3nowledge 4nfrastructure databases, and the references of the retrieved articles,researchers at the
7he8iang 9niversity found that intake of carrot demonstrated a significantly reduced risk of prostate
cancer with the odd ratio of . ! in compared to non serving group./isk of prostate cancer was decreased
by &: and ': in intake of a weekly portion of 2 g of carrot increment without precipitating adverse
effect.Dr. ;u ;, the lead author suggested that intake of carrot fre<uently with limit volume may have a
profound effect in reduced prostate cancer risk.$urther analysis of the potential effect of lycopene e=tract
found abundantly in tomato and carrot in decreased risk of onset and treatment of prostate cancer
indicated that lycopene inhibited prostate cancer proliferation through modulated the e=pression of
P4#3>Akt pathway prostate cancer cell lines in regulating cancerous cellular functions including
metabolism, growth, proliferation.Dysfunction of the P4#3>Akt pathway was associated to a number of
human diseases including cancer, diabetes, cardiovascular disease and neurological diseases.5oreover,
application of lycopene also displayed a strong effect in inhibited the proliferation of androgen?dependent
prostate@1CaP cancer cells through the activation of the pero=isome proliferator?activated receptor
gamma +PPA/ - with function to act as a tumor suppressor in prostate cells due to it activity in induction
of agonist ligands in inhibited growth of prostate cancer cells.Additionally, the phytochemical also
e=pressed a significant activity in e=hibited the liver ; receptor alpha +@;/B- in reduce proliferation of
human oral cancer cells by promoting cell cycle arrest through increased e=pression of the
cyclindependent kinase inhibitor p!), a tumor suppressor and promoted function of e=tracellular
A*P?binding cassette transporter +A CA - pathway in inhibited tumor growth through modulation of
macrophage function within the tumor, and in established a link between cholesterol homeostasis and
cancer.Application of lycopene + 2 5- in the presence of a specific antagonist of PPA/ + 60''!- or
@;/B + PP- e=erted a huge effect in reduced liver ; receptor B knockdown in induction of resistance
against @;/B in promoted the proliferation of D9 %& cells