Sunteți pe pagina 1din 7

This article appeared in a journal published by Elsevier.

The attached
copy is furnished to the author for internal non-commercial research
and education use, including for instruction at the authors institution
and sharing with colleagues.
Other uses, including reproduction and distribution, or selling or
licensing copies, or posting to personal, institutional or third party
websites are prohibited.
In most cases authors are permitted to post their version of the
article (e.g. in Word or Tex form) to their personal website or
institutional repository. Authors requiring further information
regarding Elsevier’s archiving and manuscript policies are
encouraged to visit:
http://www.elsevier.com/copyright
Author's personal copy

Complementary Therapies in Medicine (2011) 19, 122—127

available at www.sciencedirect.com

journal homepage: www.elsevierhealth.com/journals/ctim

Effect of yogic practices on lipid profile and body fat


composition in patients of coronary artery disease
Ajay Pal a, Neena Srivastava a,∗, Sunita Tiwari a, N.S. Verma a, V.S. Narain b,
G.G. Agrawal c, S.M. Natu d, Kamakhya Kumar e

a
Department of Physiology, CSMMU UP (Chhatrapati Shahuji Maharaj Medical University (erstwhile KGMU) Uttar Pradesh), India
b
Department of Cardiology, CSMMU UP (Chhatrapati Shahuji Maharaj Medical University (erstwhile KGMU) Uttar Pradesh), India
c
Department of Statistics, Lucknow University, Lucknow, India
d
Department of Pathology, CSMMU UP (Chhatrapati Shahuji Maharaj Medical University (erstwhile KGMU) Uttar Pradesh), India
e
Human Consciousness and Yogic Sciences, D. S. V. Shantikunj, Haridwar, India

KEYWORDS Summary
Yoga; Objectives: To observe the effect of regular yogic practices and self-discipline in reducing body
Coronary artery fat and elevated lipids in CAD patients.
disease; Method: In this study one hundred seventy (170) subjects, of both sexes having coronary artery
Body fat; disease were randomly selected form Department of Cardiology. Subjects were divided in to
Lipid profile two groups randomly in yoga group and in non-yoga group, eighty five (85) in each group. Out
of these (170 subjects), one hundred fifty four (154) completed the study protocol.
Time line: The yogic intervention consisted of 35—40 min/day, five days in a week till six months
in the Department of Physiology CSMMU UP Lucknow. Body fat testing and estimation of lipid
profile were done of the both groups at zero time and after six months of yogic intervention in
yoga group and without yogic intervention in non yoga group.
Results: In present study, BMI (p < 0.04), fat % (p < 0.0002), fat free mass (p < 0.04), SBP
(p < 0.002), DBP (p < 0.009), heart rate (p < 0.0001), total cholesterol (p < 0.0001), triglycerides
(p < 0.0001), HDL (p < 0.0001) and low density lipoprotein (p < 0.04) were changed significantly.
Conclusion: Reduction of SBP, DBP, heart rate, body fat%, total cholesterol, triglycerides and
LDL after regular yogic practices is beneficial for cardiac and hypertensive patients. Therefore
yogic practices included in this study are helpful for the patients of coronary artery disease.
© 2011 Elsevier Ltd. All rights reserved.

Introduction

Indians have considerably higher prevalence of premature


Abbreviations: BMI, body mass index; SBP, systolic blood pres- coronary artery disease (CAD) and mortality rates for CAD
sure; DBP, diastolic blood pressure; HDL, high density lipoprotein; compared with Europeans, Chinese and Malays.1—4 Mortal-
LDL, low density lipoprotein.
∗ Corresponding author. Tel.: +91 9415024024. ity rates due to CAD is increasing in India and it will be 100%
increase from 1985 to 2015.5 The Indian population are more
E-mail address: drneenasrivastava@rediffmail.com
(N. Srivastava). prone to CAD at a much younger age.6,7 The CAD is affecting

0965-2299/$ — see front matter © 2011 Elsevier Ltd. All rights reserved.
doi:10.1016/j.ctim.2011.05.001
Author's personal copy

Effect of yogic practices on lipid profile and body fat composition in patients of coronary artery disease 123

Figure 1 Flow of the subjects during study.

Indians 5—10 years earlier than other communities. Coro- Each subject was randomly assigned to one of the two
nary heart disease is the leading cause of morbidity and groups: (i) medication + yoga, (ii) medication, using a ran-
mortality in most industrialized societies.8 The most com- dom number generator such that equal numbers were
mon cardiovascular diseases are hypertension and coronary recruited into each group. A professional not associated with
artery disease but the basis for most cardiovascular diseases this study generated the randomization scheme with block of
is atherosclerosis which is almost universally present in the size four for up to 190 patients. These numbers were pasted
world. A study conducted in India suggests that the preva- on identical opaque envelopes containing yoga and non-
lence of CAD is about 10%.9 yoga. The numbers were noted for group 1 (yoga) and group 2
Fat is one of the nutrients that supply calories to the (non yoga) and sealed in a big envelope. After randomization
body. The relation between body fat obesity usually assessed patients in yoga and non-yoga groups were (n = 85). A senior
as body mass index (weight (kg)/height (m)2 ).10 In physical cardiologist referred all the patients after examining their
fitness, body composition is used to describe the percent- physical health and medication status. Approximately simi-
ages of fat, bone and muscle in human body. A high level of lar medications (Metoprolol/Atenolol, Aspirin, Clopidopril,
blood cholesterol leads to atherosclerosis and an increased Atorvastatin/Rosuvastatin, Ramipril/Losartan/Telmisartan)
risk of heart disease. Elevated LDL cholesterol is considered were provided to both the groups. After six months of yogic
to be a major cause of CHD.11 intervention yoga (n = 80) and non-yoga (n = 74) groups com-
pleted the study protocol. Subjects who did not participate
Research objectives in yogic intervention classes (>60% yogic practice classes)
were excluded from the study. Patients, who dropped the
study, also did not differ significantly in terms of age and
To see the effect of yogic practices on body fat and lipid
sex. Fasting glucose estimation was done once for exclu-
profile in patients of coronary artery diseases.
sion of diabetic patients. Before study all the subjects were
asked to maintain their routine activities and not initiate
Methods any new physical activities for this duration.
Those patients with clinical history e.g. angina, ECG
Study population changes of ischemic heart, treadmill positivity; history of
MI, PCI, and ≤70% narrowing in one or major coronary artery
Two hundred eight (208) subjects were selected from the and age limit 40—75 years were included for the study
Department of Cardiology CSMMU UP Lucknow India. One and patients with other co-morbid conditions like malignant
hundred seventy (170) subjects were eligible for the study. hypertension, diabetes mellitus, COPD, asthma, diseases of
Author's personal copy

124 A. Pal et al.

Table 1 Comparison of yoga and non yoga groups at base


Sample collection
line.
Five milliliters of peripheral fasting blood was collected,
Variables Yoga Non yoga following informed consent, from all individuals who par-
ticipated in this study before yogic intervention and again
Age (yrs) 58.9, 9.4 58.6, 10.5
fasting blood was collected after six months of yogic
BMI (kg/m2 ) 24.46, 4.2 25.19, 4.5
intervention in yoga group and with out intervention
TC1 (mg/dl) 159.9 149.9
in non yoga group. Serum was separated by centrifuge
TG1 (mg/dl) 135.7 105.8
machine (3500—4000 rotations/min) at room temperature.
Male 72 72
Total cholesterol, triglycerides, and HDL cholesterol were
Female 13 13
measured after overnight fasting (12 h after meal).
Abbreviations: BMI, body mass index; TC1, pre total cholesterol
level; TG1, pre triglycerides level.
Biochemical measurements

Serum total cholesterol was measured by the Cholesterol


nervous system, endocrinal disorders, and congenital heart Oxidase — Pap method, end point with lipid clearing
diseases, patients with known complications of CAD, A-V agent using the Transasia Bio-medicals Ltd. commercial kit,
block etc., on pace maker and undergone bypass surgery HDL cholesterol was determined by Phosphotungstic Acid
were excluded from the study (Fig. 1). Method, End point with Transasia Bio-medicals Ltd. commer-
Abbreviations: ECG, electro cardiogram; MI, myocardial cial kit, and triglyceride determination by dynamic extended
infarction; PCI, percutaneous coronary intervention; COPD, stability with lipid clearing agent Glycerol Phosphate Oxi-
chronic obstructive pulmonary disease; A-V block, atrioven- dase — Trinder Method, End point, Transasia Bio-medicals
tricular block. Ltd. commercial kit LDL cholesterol was calculated by
Patients were registered from March 2007 to Septem- the formula of Friedewald (LDL-cholesterol = total choles-
ber 2007, who fulfilled the inclusion criteria and willing for terol − HDL cholesterol − triglyceride/5 mg/dl).
compliance were invited to participate in the yogic inter-
ventional prospective study. This study was approved by Yogic intervention
the Institutional Research Ethics-Committee. After signed
informed consent by the subjects, anthropometric measure- Under the guidance and supervision of yoga experts and
ments were taken. faculty, subjects performed yogic practices. The yogic prac-
ticed were Jal Neti (nasal cleansing) once in a week; this
is a process of cleaning the nasal passage with salt water
Estimation of body fat composition and is essential in allowing free breathing. Shavashana
(body awareness, 10—15 min) laying flat on back in the
The body fat analyzer (bioelectrical impedance was supine position. Bhujangasana (5 times in 3 min) lying flat
obtained using a device, Tanita — TBF — 310, Japan) was on the stomach with the legs straight and the soles of the
used for assessing the BMI, fat%, fat mass, fat free mass feet uppermost. Shashankasana (5 times in 3 min) sitting
(FFM) and total body water (TBW). in Vajrasana then bending forward and placing the hand

Table 2 Comparison of difference in pre treatment and post treatment scores among yoga and non yoga groups.

Variables Difference in scores t value p value

Yoga Non yoga


n = 80Mean, sd n = 74Mean, sd

BMI 1.45, 1.74 0.96, 1.16 2.04 0.04*


Fat% 3.09, 3.36 1.28, 2.26 3.87 0.0002*
Fat mass 1.99, 2.70 2.68, 4.05 1.24 0.21
Fat free mass 1.51, 6.35 −0.54, 6.24 2.03 0.04*
Total body water 2.47, 3.26 2.95, 4.01 0.82 0.41
SBP 11.02, 9.46 7.05, 6.29 3.043 0.002*
DBP 8.85, 7.92 6.01, 4.98 2.63 0.009*
HR 4.17, 10.64 −2.32, 7.12 4.42 0.0001*
Total cholesterol 28.29, 30.86 5.31, 40.93 3.95 0.0001*
HDL 6.44, 4.92 2.00, 6.88 4.63 0.0001*
Triglyceride 38.04, 37.39 7.33, 34.82 5.26 0.0001*
LDL 15.10, 45.23 1.09, 39.64 2.05 0.04*
Abbreviations: *, statistically significant; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; HR, heart
rate; HDL, high density lipoprotein; LDL, low density lipoprotein.
Author's personal copy

Effect of yogic practices on lipid profile and body fat composition in patients of coronary artery disease 125

and foreheads rest on the floor in front of the knees. Ush-


Table 3 Comparison of unadjusted and adjusted post total
trasana (5 times in 3 min) kneel and adjust the knees and
cholesterol levels.
feet so that they are separated by the same width as the
hips. Hasthutthanasana (5 times in 3 min) inhale deeply and Types of scores Groups
slowly raising the arms above the head bending the head
slightly backward and look up at the hands. Shiddhasana Yoga Non yoga
(changing the feet, 5 min) sitting with the legs straight in Unadjusted mean TC2 140.53 143.97
front of the body. Bending the right leg and placing the sole Adjusted mean TC2 136.84 148.01
of the foot flat against the inner left thigh. Nadi Shodhan
Pranayama (5 times in 6—7 min) with om chanting (3 times Abbreviations: TC2, post total cholesterol.
in 2 min) was also done. Total duration of these practices
was 35—40 min/day, five days in week till six months in the The fitted ANCOVA models for two groups are:
Department of Physiology of the institute.
Yoga : ŷ = 85.25 − 0.55Age + 0.451TC1 + 0.115TG1 (1)

Statistical analysis Non-yoga : ŷ = 85.25 − 0.55Age + 0.451TC1


+ 0.115TG1 + 11.173 (2)
R-software version 2.7 (this can be freely downloaded by the
www.cran.r-project.org) was used in the statistical analy- The adjusted mean scores are obtained from these two
sis. For univariate analysis, differences12,13 in means were equations by taking the values of explanatory variables to
analyzed by independent ‘t’ test was used. All statistical be their average values. A comparison of the adjusted mean
tests were 2-tailed and a p value of <0.05 was considered scores with the unadjusted means gives in Table 3.
significant. Our main objective was to compare the total Notice that the adjusted mean for yoga group is slightly
cholesterol level in the two groups (yoga and non-yoga) after lower than the unadjusted mean for yoga group, whereas the
the follow-up period of six months. In order to increase non-yoga group adjusted mean is higher than its unadjusted
the precision in estimating the association of interest, the counterpart. The direction of these changes accurately
analysis of covariance model was used to take into account reflects the fact that, in this sample, the distribution of
the possible confounding effects due to age, body mass confounders such as age, pre-total cholesterol (TC1) and
index, pre-total cholesterol (pre-total cholesterol means the pre-triglycerides (TG1) in the two intervention groups are
value of cholesterol before yogic intervention at the time of different (see Table 1).
anthropometric measurement), pre-triglycerides, pre high Nevertheless, whether adjusted or not, the mean post-
density lipoprotein. The partial F-test was used to test the total cholesterol for non-yoga group appears to be higher
significance of adjusted mean scores. The test of paral- than for yoga group. The discrepancy between the non-yoga
lelism was performed before using the analysis of covariance and yoga group is 3.44 using unadjusted mean scores and
(ANCOVA) method of adjusting the cholesterol scores after 11.17 using adjusted mean scores. Using the partial F-test,
which we got results of post yogic intervention after six we see that the adjusted mean score are significantly dif-
months of yogic practices. ferent (F = 5.23, p = 0.024).

Discussion
Results
The prevalence rate of CAD is in the rural area of 4%14
Out of 170 patients 154 have finished the program and and 11% in the urban area.15 In this study the effect
completed study protocol. Table 1 summarizes demographic of yogic practices was seen on the body fat composi-
characteristics of study participants. Table 2 summarizes tion and lipid profile in the patients of CAD. Significant
pre and post-intervention changes in the variables. Com- improvement in blood pressure, heart rate and BMI was
pared to the non yoga group, the yoga group revealed a observed and other researchers also corroborate with our
pattern of improvements in BMI (p < 0.04), fat % (p < 0.0002), findings.16—18 In a research conducted in Connecticut, USA,
SBP (p < 0.002), DBP (p < 0.009), heart rate (p < 0.0001), total a six-week program of yoga and meditation was undertaken
cholesterol (p < 0.0001), triglycerides (p < 0.0001), low den- to observe the brachial artery reactivity, significant reduc-
sity lipoprotein (p < 0.04) and fat free mass (p < 0.04), HDL tions in blood pressure, heart rate, and BMI was observed in
(p < 0.0001). the total cohort with yoga.19 It was observed that yoga prac-
tice has also significantly improved BP among people with
hypertension20 and cardiovascular disease.16 It was found
Adjustments for covariates that yogic practices are useful in preventing and manag-
ing disorders related to the body systems.21 In the present
Here, the need for adjustment stems from the fact that age, study fat% and fat free mass significantly improved after
body mass index (BMI), pre treatment cholesterol level (TC1) yogic practices in yoga group. A controlled trial held in India
are the factors known to be strongly associated with post supports that yogic practices contribute to reduced exces-
treatment cholesterol level (TC2) and that the two groups, sive body fat not only among school students but also in
as sampled, may have widely different distributions of age, obese patients.22 This study assessed the feasibility of imple-
BMI, TC1 etc. The adjustment for covariate was done using menting a yoga program among patients of coronary artery
ANCOVA. diseases.
Author's personal copy

126 A. Pal et al.

Physical activity to reduce one’s risk for cardiovascu- In a study conducted in Mumbai, India, it was observed
lar disease is strongly recommended in consensus from the that in study group average total cholesterol level fell to
Centers for Disease Control and Prevention and the Ameri- 184.8 mg% (p < 0.05) from the baseline level of 247.2 mg%
can College of Sports Medicine Massachusetts, USA.23 Since (p < 0.05) and LDL cholesterol level fell to 108.4 from basal
sustained physical exercise leads to greatest total caloric of 146.4, even without the use of statins.32 In present study
expenditure; however CAD or other diseases may appear as it was seen that cholesterol level fell to 140.52 mg/dl from
over riding factors.24 Yoga might have played role as a safety the baseline level of 159.99 mg/dl and LDL cholesterol level
measure. Other study also performed in Toronto, Canada, fell to 72.97 mg/dl from baseline level of 83.78 mg/dl, but
clearly states that physically active individuals are less likely the subjects were taking medications with yogic practices
to develop hypertension than sedentary individuals.25 as subjects were CAD patients so medication could not be
We observed that level of HDL was significantly improved stopped. Another study conducted in Haridwar, India, also
after regular yogic practices in present study. A study con- reported that cholesterol level fell to 118.65 mg/dl from
ducted on patients with angina and coronary risk factors26 baseline level of 147.00 mg/dl, in this study all the subjects
have showed a positive response in lipid profile after 4—14 were healthy football player.33
weeks of yogic practices. A study held in Ontario, Canada Limitations of this study was that our study group was
also corroborate with our study and state that training taken from urban population only, keeping in mind that
increases HDL cholesterol and several studies have con- urban population is more prone for heart diseases than the
firm this belief.27 It is well known that yogic practices are rural population. Most of the variables taken in this study
beneficial for the health. The level of cholesterol, triglyc- were indirectly related to coronary artery disease. In this
eride and LDL was significantly reduced in this study after study we did not take the effect of diet though dietary factor
yogic practices. Physical exercises including yogic prac- plays a vital role in yogic interventional studies.
tices along with dietary modification have been observed In future this study could be repeated in other popu-
to control lipid content of blood and to treat and prevent lations also. Further, some other yogic practices may be
CAD. A study was conducted in Tampere, Finland also favor tried and compared with the present ones. More scientific
to the present study and mentioned that the practice of co-relations could be seen before and after yogic interven-
yoga was associated with significant decreases in choles- tions. Qualitative analysis (psychological variables) of the
terol among subjects with cardiovascular disease.28 Another subjects may be useful for discussing the variables changed
study which was conducted in California, USA on subjects after yogic intervention. Yoga may also be responsible in cre-
with mild to moderate hypertension reported that yoga can ating positive changes in plasma catecholamines, cytokines
play an important role in risk modification for cardiovascular and leukotrienes levels thus benefiting the patients. Study
diseases.29 The yogic practices have a favorable recondi- of such factor could be helpful in management of CAD for
tioning effect on endocrine gland secretion,30 reduction in clinicians and policy makers. Thus yogic intervention may be
sympathetic tone of the autonomic nervous system as well prescribed as an adjunct to medical treatment.
as in oxygen consumption and blood flow.
In the present study there were no significant changes in Conclusion
most of the variables in non-yoga group. Sivsankaran et al.
have found that none of the laboratory parameters changed Reduction of SBP, DBP, heart rate, and body fat%, total
significantly with yoga.19 There were no significant reduction cholesterol, triglycerides and LDL after regular yogic prac-
in Fat mass and Total Body Water in yoga group. Shenba- tices is beneficial for cardiac and hypertensive patients.
gavalli also reported that body fat percentage did not show Therefore yogic practices included in this study are helpful
any significant reduction due to training.31 for the patients of coronary artery disease.

Strengths and weaknesses of the study Conflict of interest

Frequency of yoga practice in present study was 5 days/week There is no conflict of interest of authors.
where as some other studies were restricted to only 4 days
training followed by practice at home.16—18 Many parame- Acknowledgements
ters were studied simultaneously in present study, whereas
only lipid profile was studied in most of the studies.19,30,31 The authors wish to acknowledge the financial support of
The duration of the yogic intervention was quite long (6 the Department of AYUSH, Ministry of Health and Family
months) in our study, many other investigators kept it for Welfare, Government of India.
few weeks only.16—18 Our findings are also corroborate with
the findings of other studies16—18 therefore reproducibility
References
becomes another very important factor in present study.
Ornish et al.34 showed short term and long term benefits of
1. Enas EA, Garg A, Davidson MA, Nair VM, Huet BA, Yusuf S.
lifestyle changes (without using cholesterol lowering drugs)
Coronary heart disease and its risk factors in first generation
on coronary lesions and clinical manifestations of coronary immigrant Asian Indians to the United States of America. Indian
artery disease (sample size, n = 28). Manchanda et al.17 have Heart J 1996;48:343—52.
showed similar benefits in Indian population (sample size, 2. Hughes K, Yeo PP, Lun KC, Sothy SP, Thai AC, Wang KW, et al.
n = 21). In both these studies, numbers of subjects were Ischemic heart disease and its risk factors in Singapore in com-
small compared to our study (170 subjects). parison with other countries. Ann Acad Med 1989;18:245—9.
Author's personal copy

Effect of yogic practices on lipid profile and body fat composition in patients of coronary artery disease 127

3. Anand SS, Yusuf S, Vuksan V, Devanesen S, Teo KK, Montague Medicine, Bridgeport Hospital, Bridgeport, Connecticut 06610,
PA, et al. Differences in risk factors, atherosclerosis and cardio- USA. Clinical Cardiology (Clin Cardiol) 2006;29(September
vascular disease between ethnic groups in Canada: the study (9)):393—8.
of health assessment and risk in ethnic groups (SHARE). Lancet 20. Blumenthal JA, Emery CF, Madden DJ, George LK, Coleman
2000;356:279—84. RE, Riddle MW, et al. Cardiovascular and behavioral effects
4. Balarajan R. Ethnic differences in mortality from ischemic of aerobic exercise training in healthy older men and women.
heart disease and cardiovascular disease in England and Wales. J Gerontol 1989;44:M147—57.
BMJ 1991;302:560—4. 21. Saraswati K, Swami. Yogic management of common diseases.
5. Bulato RA, Stephens PW. Preworking paper. Washington, DC: Munger: Bihar School of Yoga; 1986. p. 27.
Population Health and Nutrition Department, World Bank; 22. Bera TK, Gore MM, Kulkarni DD, Bhogal RS, Oak JP. Yoga
1992. p. 100. Mimansa, vol. XXXIV, nos. 3 and 4. October 2002 and January
6. Janus ED, Postiglione A, Singh RB, Lewis B. The modernization 2003. p. 166—87.
of Asia: implications for coronary heart disease. Circulation 23. Westcott WL, Winett RA, Anderson ES, Wojcik JR, Loud RL,
1996;94:2671—3. Cleggett E, et al. Effects of regular and slow-speed resis-
7. McKeigue PM, Ferrie JE, Pierpoint T, Marmot MG. Associa- tance training on muscle strength. J Sports Med Phys Fitness
tion of early onset coronary heart disease in south Asian 2001;41:154—8.
men with glucose intolerance and hyperinsulnemia. Circulation 24. Arner P, Bolinder J, Engfeld P, Ostman J. Metabolism
1993;87:152—61. 1981;30:753—60.
8. Goode GK, Miller JP, Heagerty AM. Hyperlipidemia, hyperten- 25. Shephard RJ. Absolute versus relative intensity of physical
sion, and coronary heart disease. Lancet 1995;345:362—4. activity in a dose-response context. Med Sci Sports Exerc
9. Chadha S, Radhakrishnan S, Ramachandran K, Kaul U, Gopinath 2001;33:S400—18.
N. Coronary heart disease in urban health. Indian J Med Res 26. Berg A, Konig D, Diebert P, Grathwohl D, Berg A, Baumstark
1990;72:424—30. MW, et al. Effect of an oat bran enriched diet on the athero-
10. WHO physical status: the use and interpretation of anthro- genic lipid profile in patients with an increased coronary heart
pometry. Report of a WHO Expert Committee. WHO Technical disease risk. Ann Nutr Metab 2003;47:306—11.
Report Series 854. Geneva: World Health Organization; 1995. 27. Katzmarzyk PT, Leon AS, Rankinen T, Gagnon J, Skinner JS,
11. Expert panel on detection, evaluation, and treatment of high Wilmore JH, et al. Changes in blood lipids consequent to aer-
blood cholesterol in adults. JAMA 2001;285:2486—97. obic exercise training related to changes in body fatness and
12. Guyatt G, et al. Measuring changes over time: assess- aerobic fitness. Metabolism 2001;50:841—8.
ing the usefulness of evaluative instruments. J Chronic Dis 28. Asikainen TM, Miilunpalo S, Kukkonen-Harjula K, Nenonone A,
1987;40:171—7. Panasen M, Rinne M, et al. Walking trials in post menopausal
13. Mackenzie CR, et al. Can the sickness impact profile mea- women: effect of low doses of exercise and exercise frac-
sure change: an example of scale measurement. J Chronic Dis tionization on coronary risk factors. Scand J Med Sci Sports
1986;39:429—38. 2003;13:284—92.
14. Rao GHR. Coronary artery disease in South Asians. 1st ed. New 29. Stefanick ML, Mackey S, Sheehan M, Ellsworth M, Haskell
Delhi: Jaypee Brothers Medical Publishers (P) Ltd.; 2001. p. WL, Wood PD. Effects of diet and exercise in men and
6—28. postmenopausal women with low levels of HDL cholesterol
15. Mohan V, Deepa R, Rani SS, Premalatha G. Prevalence of coro- and high levels of LDL cholesterol. N Engl J Med 1998;339:
nary artery disease and its relationship to lipids in a selected 12—20.
population in South India. The Chennai urban population study 30. Copeland P. Yoga and the endocrine system. Yoga
(CUPS No5). J Am Coll Cardiol 2001;38:682—7. 1975;(July—August).
16. Mahajan AS, Reddy KS, Sachdeva U. Lipid profile of coro- 31. Shenbagavalli A. Yoga Mimansa, vol. XXXIV, nos. 3 and 4. Jan-
nary risk subjects following yogic lifestyle intervention. Indian uary 2003, October 2002. p. 166—87.
Heart J 1999;51:37—40. 32. Yogendra J, Yogendra HJ, Ambardekar S, Lele RD, Shetty
17. Manchanda SC, Narang R, Reddy KS, Sachdeva U, Prabhakaran S, Dave M, et al. Beneficial effects of yoga lifestyle
D, Dharmanand S, et al. Retardation of coronary atheroscle- on reversibility of ischaemic heart disease: caring heart
rosis with yoga lifestyle intervention. J Assoc Physicians India project of International Board of Yoga JAPI, vol. 52, April
2000;48:687—94. 2004.
18. Bijlani RL, Vempati RP, Yadav RK, Ray RB, Gupta V, Sharma 33. Acharya BK, Upadhyay AK, Upadhyay RT, Kumar A. Effect of
R, et al. A brief but comprehensive lifestyle education pro- Pranayama (voluntary regulated breathing) and Yogasana (yoga
gram based on yoga reduces risk factors for cardiovascular postures) on lipid profile in normal healthy junior footballers.
disease and diabetes mellitus. J Altern Complement Med Int J Yoga 2010;3(July—December (2)):70.
2005;11:267—74. 34. Ornish D, Brown SE, Scherwitz LW, Billings JH, Armstrong WT,
19. Sivasankaran S, Sachdeva S, Sachdeva R, Pugeda J, Hoq SM, Stu- Ports TA. Can lifestyle changes reverse coronary heart disease?
art et al. Division of Cardiovascular Medicine, Department of Lifestyle Heart Trial Lancet 1990;336:129—33.

S-ar putea să vă placă și