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The cornea
a Has an endothelial layer that regenerates readily.
b Comprises three layers.
c The endothelium actively pumps water from the stroma.
d Is an important refractive component of the eye.
e Has a stroma composed of randomly arranged collagen fibrils.
2. The retina
a Is ten layers thick.
b Has ganglion cells whose axons form the optic nerve.
c Has three types of rods responsible for colour vision.
d The neuroretina is fi rmly attached to the retinal pigment epithelium.
e The RPE delivers vitamin A for rhodopsin production.
3. The lens
a Grows throughout life.
b Is surrounded by a collagenous capsule.
c Cortical and nuclear fi bres are nucleated.
d Has a high refractive index owing to its protein content.
e Changes in shape with accommodation.
6. The tear fi lm
a Is 100 μ m thick.
b Is composed of four layers.
c The mucin layer is in contact with the cornea.
d Is important in the refraction of light entering the eye.
e Contains lysozyme and secretory IgA.
10. Match the description with the most likely diagnosis. A patient presents
with:
a A diffusely red, sticky eye; vision is unaffected.
b A red eye most marked at the limbus, with photophobia and blurred vision.
c Sudden onset of a local red patch on the sclera, associated with slight
discomfort but with normal vision. The patient takes warfarin.
d A painful red eye and slightly blurred vision. The patient suffers from
rheumatoid arthritis.
e A painful red eye, very blurred vision and discharge. There is a history of
contact lens wear.
i Corneal ulcer.
ii Optic neuritis.
iii Scleritis.
iv Uveitis.
v Allergic conjunctivitis.
vi Subconjunctival haemorrhage.
vii Episcleritis.
viii Bacterial conjunctivitis.
ix Corneal abrasion.
x Corneal foreign body.
12. Match the description with the most likely diagnosis. A patient presents
with:
a Floaters, flashes of light and a curtain - like loss of vision.
b Sudden loss of vision in one eye, jaw claudication and shoulder pain.
c A painful red eye, loss of vision, nausea.
d Loss of vision for seconds on standing from lying down.
e Loss of vision over a couple of days associated with pain on eye movement.
i Optic neuritis.
ii Retinal vein occlusion.
iii Retinal artery occlusion.
iv Retinal detachment.
v Acute glaucoma.
vi Vitreous haemorrhage.
vii Orbital cellulitis.
viii Raised intracranial pressure.
ix Giant cell arteritis.
x Endophthalmitis.
13. Match the description with the most likely diagnosis. A patient presents
with:
a A watering eye present since birth, associated with intermittent stickiness
but no redness of the conjunctiva.iii
b A watering eye in a 6 - month - old child associated with a large cornea. The
eye is not red. vi
c A watering eye in a 60 - year - old man, associated with a lower lid that
droops away from the eye. viii
d A sticky, watery, white eye in a 55 - year - old woman.iv
e An acute, watery, red eye associated with photophobia in a 26 - year - old
man. i
i Viral conjunctivitis.
ii Corneal ulcer.
iii Congenital nasolacrimal duct obstruction.
iv Acquired nasolacrimal duct obstruction.
v Corneal foreign body.
vi Congenital glaucoma.
vii Migraine.
viii Ectropion.
ix Entropion.
x Molluscum contagiosum.
14. Match the description with the most likely diagnosis. A patient presents
with:
a Gradual loss of vision over some months, with increasing glare in the sun. iv
b Gradual loss of vision followed by more rapid loss, associated with distortion
of central vision. v
c Gradual loss of vision in the right eye, associated with a relative afferent
pupillary defect. vii
d Gradual loss of vision in both eyes, with no relative afferent pupillary
defect or media opacity. i
e Gradually increasing blurring of vision some months following cataract
surgery. ix
i Pituitary tumour.
ii Cortical infarct.
iii Corneal ulcer.
iv Cataract.
v Age - related macular degeneration.
vi Macular oedema.
vii Optic nerve compression.
viii Retinal detachment.
ix Posterior capsule opacification.
15. Name the major sign in each of the photographs (Figure 2.13 ).
16. Name the sign or condition in each case (Figure 2.14 ).
17. What does this pathological section show (Figure 2.15 )? What is the
diagnosis?
18. What does this radiograph show (Figure 2.16 )? What is the diagnosis?
How might the eyes be affected?
19. Physiological testing of the eye
a The Snellen chart measures visual acuity, the resolving power of the eye.
b The Snellen chart is positioned at 4 m from the patient.
c The Cardiff Acuity Test relies on preferential looking.
d An isoptre on a visual fi eld chart represents the eye ’ s ability to see a point
of light of given size and brightness.
e Intraocular pressure is measured with a perimeter.
20. Pupils
a The term miosis means a constricted pupil.
b Anisocoria means that the pupils differ in size.
c Damage to oculomotor parasympathetic fibres causes miosis.
d A relative afferent pupillary defect indicates optic nerve disease.
e Normal pupils dilate during convergence.
21. Lids
a When the lid margin is turned away from the eye, this is ectropion.
b When the lid margin is turned into the eye, this is entropion.
c A third nerve palsy may cause ptosis.
d In myasthenia repeated lid blinking increases any ptosis.
22. Fluorescein
a Is excited by green light and emits in the blue wave band.
b Will stain a corneal abrasion.
c To detect its fluorescence, the eye must be examined with a blue light.
d Can be used to demonstrate a leak of aqueous from the anterior chamber.
e Is used to examine the vasculature of the retina.
24. Instruments
a Keratometry allows the protrusion of the eye to be measured.
b The synoptophore measures convergence and divergence.
c The exophthalmometer measure corneal shape.
d Retinoscopy is used to assess refractive error.
ORBIT:
2. A 16 - year - old boy presents with swollen eyelids, a red eye, proptosis,
severe eye pain and tenderness and a pyrexia. The vision has become very
blurred and colour vision is reduced.
a Orbital cellulitis is the most likely diagnosis.
b A relative afferent pupillary defect may be present.
c No investigations are necessary.
d Urgent orbital decompression is indicated.
3. A 70- year - old woman with a history of previous head trauma presents
with sudden onset of a red, proptosed eye. Eye movements are reduced in
all directions. Vision is intact. Intraocular pressure is increased. The most
likely diagnosis is:
a Dysthyroid eye (Graves ’) disease.
b A caroticocavernous sinus fistula.
c An orbital varix.
d A dermoid cyst.
THE EYELIDS:
1. A 55 - year - old woman presents with a small ptosis, and miosis on the same
side. She is a smoker. The likely diagnosis is
a Myasthenia gravis.
b Marcus – Gunn syndrome.
c Horner ’ s syndrome.
d Third nerve palsy.
e Conjunctival scarring.
2. A 60 - year - old man presents with painless watering of the eye, worse when
outside in the wind. Sometimes there is a sticky discharge. The white of
the eye is never inflamed. No abnormal masses are palpable, but pressure
over the lacrimal sac causes a mucopurulent discharge to be expressed
from the lower punctum.
a The most likely diagnosis is an ectropion.
b The most likely diagnosis is a blocked nasolacrimal duct.
c The site of a nasolacrimal obstruction can be confirmed with a
dacrocystogram.
d The most likely diagnosis is blepharitis.
e The most likely diagnosis is dacrocystitis.
1. An 11 - year - old child presents with a red watery eye and slightly blurred
vision. Her sister had similar symptoms a week ago. The appearance of
the eye is shown in Figure 7.14 .
a The most likely diagnosis is uveitis.
b The most likely diagnosis is viral
conjunctivitis.
c The most likely diagnosis is bacterial
conjunctivitis.
d The child should be treated with steroids.
e Papillae are present as elevations on the lid
mucosa.
2. A 26 - year - old patient presents with an itchy watery eye. She is
photophobic
and the vision has become blurred. She has a history of asthma. The
appearance of the eye is shown in Figure 7.15 .
a The most likely diagnosis is uveitis.
b The most likely diagnosis is epithelial herpes simplex keratitis.
c The most likely diagnosis is allergic conjunctivitis.
d Treatment is with antihistamines, mast cell stabilizers and topical
steroids.
e Treatment is with aciclovir.
3. A 67 - year - old lady presents with pain on the right side of her forehead.
She has been feeling generally unwell. She has just noticed the appearance
of vesicles on the skin.
a The most likely diagnosis is herpes simplex.
b The most likely diagnosis is herpes zoster.
c The most likely diagnosis is acanthamoeba keratitis.
d Ocular complications may include keratitis, iritis and secondary glaucoma.
e The patient should be prescribed systemic aciclovir in high dosage.
4. A contact lens wearer presents with a red painful eye. There is a purulent
discharge and vision is decreased. Figure 7.16 shows the appearance of
the eye.
1. Cataract causes:
a A sudden loss of vision.
b A gradual loss of vision.
c Glare.
d Photophobia.
e A change in refractive error.
UVEITIS:
2. Uveitis
a Is always associated with a red eye.
b May be complicated by macular oedema.
c Posterior synechiae may form between the iris and the lens.
d May cause oculomotor palsies.
e May be associated with retinitis.
3. A 33 - year - old West Indian patient presents with a red eye, without
discharge, and with photophobia and blurred vision. The eye is
uncomfortable.
He has recently become short of breath and developed painful,
raised, tender red lesions on his shins.
a The patient has uveitis.
b The patient has ankylosing spondylitis.
c The patient probably has sarcoidosis.
d Treatment is with steroid eye drops and cycloplegics.
e Glaucoma and cataract are possible ocular complications of the condition
or its treatment.
GLAUCOMA:
3. A patient presents to casualty with a painful red eye and a cloudy cornea.
The casualty officer suspects he has acute glaucoma.
a He should arrange for him to be seen in the eye clinic in a week.
b The diagnosis would be further confirmed by finding a dilated pupil.
c Treatment is initially with intravenous acetazolamide and pilocarpine eye
drops.
d A laser iridotomy should be performed.
e The condition may be caused by a block to the flow of aqueous through the
pupil.
1. Match the symptoms with the likely abnormal part of the retina.
a Distortion of vision (metamorphopsia).
b Loss of superior visual field.
c Difficulty seeing at night.
i The inferior half of the retina.
ii The macula.
iii The rods.
iv The cones.
6. A 1 - year - old child presents with a squint. The doctor notices that the red
reflex appears white.
a A white red reflex is a normal finding in a child of this age.
b The child may have a retinoblastoma.
c The child has albinism.
d Urgent referral is required.
e The other eye needs to be assessed.
3. Diabetic retinopathy
a Is seen in 80% of patients who have had diabetes for 20 years.
b Control of systemic hypertension is important in reducing the severity of the
retinopathy.
c The number of pericytes around the capillaries is increased.
d Vitreous haemorrhage is associated with the formation of new vessels on
the retina or optic nerve head.
e Circinate patterns of exudates are treated with scattered laser.
5. Retinopathy of prematurity
a Is caused by a failure of normal retinal vascularization.
b Is most commonly seen in babies with a low birthweight.
c Is less commonly seen in babies exposed to supplementary oxygen.
d New vessels and haemorrhages may be seen in the retina.
e Retinal detachment may complicate the condition.
THE PUPIL AND ITS RESPONSES:
4. Optic neuritis
a Is associated with a sudden loss of vision that does not progress.
b Is painless.
c May be part of a systemic neurological disease.
d Vision rarely recovers.
e Is associated with a reduction in colour vision.
3. Amblyopia
a Refers to a developmental reduction in visual acuity.
b May be caused by Duane ’ s syndrome.
c May be caused by a previously unidentified difference in refractive correction
between the two eyes.
d May be caused by a squint.
e May be treated by patching the amblyopic eye.
4. Nerve palsies affecting the third, fourth on sixth cranial nerves may be
seen in
a Orbital disease.
b Raised intracranial pressure.
c Ischaemia of the cerebral cortex.
d Systemic inflammatory disease
e Trauma
5. Internuclear ophthalmoplegia
a Is caused by a lesion of the medial longitudinal fasciculus.
b Manifests as a reduced adduction and contralateral nystagmus in the
abducting eye.
c Is manifested by a failure of the eye to elevate in adduction.
d May be caused by demyelination.
e Requires surgical treatment.
TRAUMA:
1. Orbital injury may produce the following signs
a Periorbital emphysema.
b Limitation of eye movements.
c Exophthalmos in the longer term.
d A patch of anaesthesia below the orbital rim.
e Hyphaema.
2. A subconjunctival haemorrhage
a Is never associated with serious eye disease.
b May cause blood to pass into the cornea.
c Is usually associated with a reduced vision.
d May be associated with some discomfort of the eye.
e Usually settles in a couple of weeks.
4. A hyphaema
a Is a fluid collection of white cells in the anterior chamber.
b May be associated with a low intraocular pressure.
c Is treated with restriction of activity.
d If it recurs within a short time may result in more severe problems.
e Is treated with steroid drops.
TROPICAL OPHTHALMOLOGY:
1. Orbital injury may produce the following signs
a Periorbital emphysema.
b Limitation of eye movements.
c Exophthalmos in the longer term.
d A patch of anaesthesia below the orbital rim.
e Hyphaema.
2. A subconjunctival haemorrhage
a Is never associated with serious eye disease.
b May cause blood to pass into the cornea.
c Is usually associated with a reduced vision.
d May be associated with some discomfort of the eye.
e Usually settles in a couple of weeks.
4. A hyphaema
a Is a fl uid collection of white cells in the anterior chamber.
b May be associated with a low intraocular pressure.
c Is treated with restriction of activity.
d If it recurs within a short time may result in more severe problems.
e Is treated with steroid drops.