Exercise 10: Acid-Base Balance: Activity 4: Respiratory Responses to Metabolic Acidosis and Metabolic Alkalosis Lab

Report

Pre-lab Quiz Results

You scored 100% by answering 4 out of 4 questions correctly.

1. An increase in metabolic rate (without compensation) would result in

You correctly answered: a. more carbon dioxide in the blood.

2. Excessive vomiting results in

You correctly answered: c. loss of acid, metabolic alkalosis.

3. Which of the following is not acidic?

You correctly answered: d. antacids

4. Which of the following decreases the rate of metabolism?

You correctly answered: b. lowered body temperature

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Experiment Results
Predict Question:
Predict Question 1: What do you think will happen when the metabolic rate is increased to 80 kcal/hr?
Your answer : a. metabolic acidosis

Predict Question 2: What do you think will happen when the metabolic rate is decreased to 20 kcal/hr?
Your answer : d. Breaths per minute will decrease.

Stop & Think Questions:

The tidal volume and breaths per minute increased with increased metabolism because
You correctly answered: b. there is more carbon dioxide being formed.

Which body system is compensating for the metabolic alkalosis?

You correctly answered: c. respiratory

Experiment Data:

Metabolic Rate BPM (breaths/min) Blood pH PCO2 [H+] [HCO3-]

(kcal/hr) in Blood in Blood
50 15 7.41 40 40 24
60 17 7.34 45 47 20
80 21 7.27 55 63 14.50
40 13 7.43 37 38 26
20 9 7.51 31 32 30

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Post-lab Quiz Results
You scored 100% by answering 4 out of 4 questions correctly.

1. What happened to the breathing when metabolism was increased?

You correctly answered: d. The breaths per minute and the tidal volume increased.

2. Which of the following is not a cause of metabolic acidosis?

You correctly answered: b. constipation

3. If PCO2 in the blood increases, then

You correctly answered: a. [H+ ] increases and pH decreases.

4. Which of the following values increased with decreased metabolism?

You correctly answered: d. pH and [HCO3- ]

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Review Sheet Results
1. Describe what happened to the blood pH when the metabolic rate was increased to 80 kcal/hr. What body system was
compensating? How well did the results compare with your prediction?
Your answer:
Blood pH dropped. The respiratory and renal system were compensating.
This was my prediction.

2. List and describe some possible causes of metabolic acidosis.

Your answer:
Loss of bicarbonate through diarrhea or renal dysfunction
Accumulation of acids (lactic acid or ketones)
Failure of kidneys to excrete H+
High intake of alchohol which metabolizes into acetic acid

3. Describe what happened to the blood pH when the metabolic rate was decreased to 20 kcal/hr. What body system was
compensating? How well did the results compare with your prediction?
Your answer:
The pH in the blood increased. The respiratory system was compensating.
This was my prediction.

4. List and describe some possible causes of metabolic alkalosis.

Your answer:
Excess vomiting = loss of stomach acid
Excessive use of alkaline drugs
Certain diuretics
Endocrine disorders
Severe dehydration

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