CLUB STATA 2-05-2014

stcox VOO NUTS, strata(ctr)

No. of subjects = 7447 Number of obs = 7447
No. of failures = 1078
Time at risk = 31007.15583
LR chi2(2) = 32.07
Log likelihood = -6639.6878 Prob > chi2 = 0.0000
------------------------------------------------------------------------------
_t | Haz. Ratio Std. Err. z P>|z| [95% Conf. Interval]
-------------+----------------------------------------------------------------
VOO | .6551205 .0492654 -5.62 0.000 .5653409 .7591576
NUTS | .8351005 .0614781 -2.45 0.014 .7228952 .964722
------------------------------------------------------------------------------
Stratified by ctr
0.25
Incidence of combined outcome

Control
0.20

MeDiet+
Nuts
0.10 0.15

MeDiet+
EVOO
0.05 0.00

0 1 2 3 4 5
Years
Number at risk
g = Control 2450 2244 1960 1522 1203 882
g = MeDiet+EVOO 2543 2467 2282 1932 1623 1239
g = MeDiet+Nuts 2454 2327 2053 1597 1314 945

stcox VOO NUTS, strata(ctr) tvc(VOO NUTS)

------------------------------------------------------------------------------
_t | Haz. Ratio Std. Err. z P>|z| [95% Conf. Interval]
-------------+----------------------------------------------------------------
main |
VOO | .4964254 .0764622 -4.55 0.000 .3670686 .6713683
NUTS | .6477294 .0953744 -2.95 0.003 .4853546 .8644266
-------------+----------------------------------------------------------------
tvc |
VOO | 1.093829 .0467625 2.10 0.036 1.005911 1.189431
NUTS | 1.08788 .0457806 2.00 0.045 1.001753 1.181413
------------------------------------------------------------------------------
Stratified by ctr
Note: variables in tvc equation interacted with _t
***OTRO MODO- MENOS DRÁSTICO
gen FC_6=floor(FU)
recode FC_6 (6/max=6)
stset FC_6, failure(D==1)
stcox VOO NUTS, strata(ctr)
est store A
stcox VOO NUTS, strata(ctr) tvc(VOO NUTS)
lrtest A .
Likelihood-ratio test LR chi2(2) = 2.30
(Assumption: A nested in .) Prob > chi2 = 0.3172

***DESCRIBIR INTERACCIÓN CON TIEMPO

gen ev0= D
replace ev0=0 if FU>2
gen PY_0=FU
replace PY_0=2 if FU>2
stset PY_0, fail(ev0==1)
stcox VOO NUTS, strata(ctr) vce(robust)
No. of subjects = 7447 Number of obs = 7447
No. of failures        =                  329
------------------------------------------------------------------------------
| Robust
_t | Haz. Ratio Std. Err. z P>|z| [95% Conf. Interval]
-------------+----------------------------------------------------------------
VOO | .5018714 .0690584 -5.01 0.000 .3832353 .657233
NUTS | .6323814 .0823455 -3.52 0.000 .4899367 .8162407
------------------------------------------------------------------------------

gen ev2= D
replace ev2=0 if FU<2 | FU>4
gen PY_2=FU
replace PY_2=4 if FU>4
replace PY_2=0 if FU<2
stset PY_2, fail(ev2==1)
stcox VOO NUTS, strata(ctr) vce(robust)
àeventos:  371  
------------------------------------------------------------------------------
| Robust
_t | Haz. Ratio Std. Err. z P>|z| [95% Conf. Interval]
-------------+----------------------------------------------------------------
VOO | .7066152 .0919883 -2.67 0.008 .5474849 .9119977
NUTS | .9864933 .1236941 -0.11 0.914 .7715498 1.261317
------------------------------------------------------------------------------
stset PY_4, fail(ev4==1)
àeventos:  379  
------------------------------------------------------------------------------
| Robust
_t | Haz. Ratio Std. Err. z P>|z| [95% Conf. Interval]
-------------+----------------------------------------------------------------
VOO | .7833027 .0992838 -1.93 0.054 .6109978 1.004198
NUTS | .9284987 .119499 -0.58 0.564 .7214905 1.194901
------------------------------------------------------------------------------

di 329+371+379 = 1078