Sunteți pe pagina 1din 6

Special Communication

Eleven Worthy Aims for Clinicai


Leadership of Health System Reform
Oonald M. Berwick, MO

Clinicians ought to be playing a central role in making the changes in the health Even in their own local organizations,
care system that will allow the system to offer better outcomes, greater ease of such as hospitaIs anel group practices,
use, lower cost, and more social justice in health status. Instead, most of the physicians are feeling less anel less in
proposed changes that are today called "health care reform" are actually changes control of the circumstances of proviel-
in the surroundings of care rather than changes in the care itself. Clinicians have ing care as they are asked to accept
protocols, guielelines, criticaI paths, anel
an opportunity to exercise leadership for the improvement of care, but they must
new management systems. 1,2
first agree to address the aims of reform and to adopt an agenda of specific
changes in their own work that are likely to meet the social needs driving the
reform movement. Health services research offers a sound scientific basis for See also p 803.
identifying promising improvement aims for clinician-Ied reformo Eleven plausible
aims are these: (1) reducing inappropriate surgery, hospital admissions, and di- Notwithstanding the resulting sense
agnostic tests; (2) reducing key underlying root causes of i1lness (especially of helplessness among so many profes-
smoking, handgun violence, preventable childhood injuries, and alcohol and co- sionals, the central premise ofthis artiele
caine abuse); (3) reducing cesarean section rates to pre-1980 leveis; (4) reduc- is this: only those who proviele care can in
ing the use of unwanted medicai procedures at the end of life; (5) simplifying the enel change care. Efforts to reform
pharmaceutical use, especially for antibiotics and medication of the elderly; (6) the health care system from the outsiele
increasing active patient participation in therapeutic decision making; (7) de- through revisions in payment, corporate
relationships, regulation, anel reporting
creasing waiting times in health care settings; (8) reducing inventory leveis in
of outcomes can help motivate and set
health care organizations; (9) recording only useful information only once; (10) the stage for improvement. Yet, if phy-
consolidating and reducing the total supply of high-technology medicai and sur- sicians, nurses, pharmacists, clinicaI tech-
gical care; and (11) reducing the racial gap in infant mortality and low birth weight. nicians, operating managers, anel others
Health care professions and their professional organizations in concert should at the front line ofhealth care elo not wish
embrace these 11 aims, establish measurements of progress toward them, and to make specific changes in their own
commit to continuous and fundamental changes in their pursuit. work to better meet society's neeels for
(JAMA. 1994;272:797-802) better outcomes and Iower cost, no one
outsiele the health care system can be
eleveI' enough OI' powerful enough to make
PHYSICIANS, in conce1t with others ofthe changes proposeel are not really in them do it-at least not well 01' for very
who provide care, can themselves achieve the ways we give health care; they are longo What will happen instead is simple
the purposes ofhealth system reformo In insteael changes in the environment of anel bael: less care anel worse care.
fact, we should; alI of the visible alterna- health care-the regulations, the pay- The reverse is also true. If the clini-
tives are worse. Clinician-Ied refonn, how- ment, anel the corporate structures un- cians ofthe nation ever see fit collectively
ever, would require that we establish elear der which the work is done. It is as ifwe to eleelare the aims of health system re-
improvement aims, monitor our progress, were trying to improve skiing by chang- form to be thei1' aims anel shoulel they
and above all willingly make changes in ing the rules of competition, the color of ever set about enthusiastically to improve
the way we do our work in an effort to the meelals, anel the location of the hill their own work with the objectives of
better meet the aims. A true commit- without spending much time at all on reform fully in minel, they coulel not easily
ment to improvement would be manifest changes in skiing itself. be stopped. If clinicians want to stop feel-
in our willingness to change. The preelictable result is fear within ing battereel by health system refonn,
Instead, we are struggling for stabil- the health care professions. We experi- they can elo so by achieving the aims of
ity. That is no surprise given the pre- ence the changes as outsiele not inside health system reform themselves. It
vailing approaches to change in health our work. Most physicians feellike pas- woulel be the best solution, but it cannot
care. The rhetoric of "health care re- sive witnesses to corporate restructur- be elone by fighting for the pasto
form" often mentions change, but most ing of health care organizations, merg- Motivating health system reform are
ers and acquisitions among them, new social neeels in four basic categories: (1) to
financiaI relationships between physi- improve the health status of populations
From the Institute for Healthcare Improvement, 80s- cian groups and hospitaIs, continuing anel to achieve better clinicaI outcomes of
ton, Mass. shifts of care from inpatient to outpa- care; (2) to improve the experience of
8ased on a paper presented at the Fifth Annual Na-
tional Forum on Quality Improvement in Health Care tient settings, anel gl'owth in the pro- care for patients, families, anel communi-
sponsored by the Institute for Healthcare Improvement, portion of prepaiel anel managed care. ties; (3) to reeluce the total economic bur-
Orlando, Fia, Oecember 8, 1993. Governments and business alliances are den of care anel illness beginning with the
Repnnt requests to Institute for Healthcare Improve-
ment, 1 Exeter Plaza, Floar 9, Boston, MA 02116 (Or threatening 01' actually enforcing new price of health care coverage; anel (4) to
Berwick). performance measurement systems. improve social justice anel equity in the

JAMA, September 14, 1994-Vol 272, No. 10 Aims for Health System Reform-Berwick 797
health status of Americans. ranges between 20% and 70%.16 Thanks naires, clinicians can detect alcohol abuse
Breakthroughs are unlikely through to a decade of development by scholars at and depression in earlier and less haz-
the prevailing, blunt, across-the-board RAND and elsewhere, simple and reli- ardous tages. 45 In large measm'e, how-
budget cuts and organizational down- able procedm-es exist for assessing the ever, knowledge about the social, be-
sizing now under way, but at bottom, appropriateness of care, and these pro- havioral, and environmental causes of
the social demands that motivate the cedures can be adapted for use by phy- disease frustrates physicians. How can
call for reform are reasonable. Decades sicians in community settings. 24 Specific, we, trained as we are in curative care
of sound health services research leave targeted efforts to involve clinicians in and palliative care after the fact, ever
litt1e doubt that clinicians themselves peer-comparison studies, education, and really reach the sources of the illnesses
could make great progress in every one coliaborative guideline development of- we treat? Is it, after all, our job to do so?
of these areas. ten result in substantial declines in pro- Strong social currents suggest that it
cedm'e rates, with a consequent reduc- may be. Social support is resurging for
ELEVEN WORTHY AIMS tion in both costs and hazards to patients. 25 public health and prevention,45 reflected
Imagine that the leading organizations Those who regulate, measure, or pur- in governrnental budgets, community-
in American medicine, nursing, and re- chase health care understandably tend wide health status improvement efforts,
lated professions (in a community, a state, to treat this problem of inappropriate- and an emphasis on primary care in many
01' the nation as a whole) declared un- ness from their own outside perspec- health system reform proposals. Of
equivocally that the aims ofreform-bet- tive-hence the current infatuation with course, so far the signals are still rnixed,
ter outcomes, better experiences, lower protocols, guidelines, algorithms, and as every physician knows. No one pays
cost, and more justice-were indeed their criticai paths. The trend is worrisome. yet for a physician to become a leader in
aims, that the professions were ready and A guideline enforced from outside may community-wide prevention of automo-
willing to make substantial changes in lead to more predictable care, but it can- bile accidents, smoking cessation pro-
their work to achieve those aims, and not lead to the continuai improvement grams, or handgun control. A specialist
that they intended to do it together, in of care. The outsider can judge care, but paid thousands of dollars for the termi-
coliective stewardship of the health and only the insider can improve it. nal care of a cirrhotic patient is paid
health care of Americans. The commitment to improving the little or nothing for community work to
The next step after such a commit- match between scientific knowledge and prevent alcohol abuse. A hospital, like
ment would be to translate the broad actual practice, the commitment to "appro- the Magic Valley MedicaI Center in Twin
goals of reform into a specific agenda- priateness," must come from the profes- Falls, Idaho, that successfully reduce .
the insiders' agenda-{)fimprovements, sionals-nm'Ses, physicians, and manag- head injuries in children by leading com-
just as a skier who intends to race faster ers-whose actions constitute the care. munity-wide bicycle safety efforts 46 still
must focus attention on specific, improv- To improve appropriateness, we must takes a significant negative strike to its
able elements of skiing, such as edging, begin with a clearheaded understanding bottom line, because it loses emergency
body position, waxes, timing, and per- that in our hands unnecessary care does department revenues as a result. No
sonal endurance. exist; it is our well-meaning inappropri- one yet totaIs and adjusts the economics
Selecting foci in health care is diffi- ateness, it is pervasive, and physician by to encourage more and more preventive
cult, in part because so many opportu- physician, organization by organization, activity in the nation.
nities for specific improvement appear we can reduce it without guilt, censm'e, Yet, the duty remains. Even though
in the research literature. As a staI'ting 01' severe externai controls. health care financing current1y works
point, the following 11 aims are particu- against it, a commitment to improve-
larly promising. For each, research Aim 2: Improve Health Status ment requires that clinicians carry their
hows a large gap between ouI' current Through Reduction in Underlying work effort to the sources of disease.
performance and what is within our Root Causes 01 IIIness Physicians strongly influence commu-
reach if we are willing to change. The underlying root causes of illness nity attitudes toward appropriate health
include smoking,26-31 handgun violence,22-35 investments, and it is therefore impor-
Aim 1: Reduce the Use 01 preventable injuries in children,'l&-38 and tant for physicians not just to counte-
Inappropriate Surgery, Hospital alcohop9 and cocaine abuse. 40 The causes nance prevention, but also to lead it.
Admissions, and Diagnostic Tests of the majority of both deaths and years
Important initial targets include man- of potentiallife lost in the United States Aim 3: Reduce Cesarean Section
agement of stage I and stage II breast are preventable.41.42 McGinnis and Foege43 Rates to Below 10% Without
cancer,3-5 prostatectomy,6 carotid en- have recent1y offered a brilliant reclas- Compromise in Maternal
darterectomy,7 coronary artery bypass sification of "actual causes of death" in or Fetal Outcomes
surgery, treatment of low-back pain,9 the United States, showing that tobacco, Cesarean section rates in the United
hysterectomy,1O endoscopy, li blood trans- diet and activity patterns, toxic agents, States have risen from 5% to 25% over
fusion, 12 chest roentgenograms, 13and pre- firearms, sexual behavior, motor vehicles, two decadesY Rates well below 10%
natal ultrasound. U and illicit use of drugs account collectively have been maintained in some other de-
Aprocedure i "inappropriate" in a par- for 50% of ali deaths each year in the veloped nations48 (and as low as 1.3% in
ticular patient if there is no scientific ba- United States. Unintentional injuries, sui- certain practice settings49) without any
sis on which to predict benefit. The re- cide, and homicide account for 30% of all demonstrated compromise in maternal
lationship between variation in practice years of potential life lost under the age and fetal outcomes.
and inappropriate care is far from of 65 years. 44 In industries other than health care,
straightforward; high-use areas are not In their own office-based practices, dramatic improvements have sometimes
necessarily areas of high inappropriate- clinicians have substantial opportunities been motivated by the setting of"stretch
ness. l 5-17 However, research consistent1y to affect some of the behavioral causes goals," goals so demanding that they chal-
shows that inappropriate surgel)', 15-20 ad- of illness. Skilled counseling by physi- lenge prevailing assumptions and auto-
missions,21 and testing2223 are common; cians can reduce smoking, high-risk matically require reconsideration of the
for a group of carefully studied surgical sexual activities, and some forms of un- system as a whole. A stretch goal makes
procedm'e ,the rate of inappropriate use intentional injury. With simpie question- the need for fundamental change clear,

798 JAMA, September 14, 1994-Vol 272. No. 10 Aims for Health System Reform--8erwick
because it is absolutely unattainable Aim 6: Increase the Frequency comes an acceptable and common fOIm of
within the existing work proces . The With Which Patients Participate adjustment to resource constraints. lt is
cesarean section rate is a candidate for Actively in Decision Making precisely at such times, however, that
stretch goals. Returning safely to the US About Medicai Interventions waiting must be UIUnasked as the thief it
rates of the mid 1970s (well below A growing amount of experimental lit- really is. Often queues add cost and rob
10%) will require fundamental system erature documents the payoff from help- opportunities as more and more time and
changes. 50·51 What we do know is that it ing patients to consider explicitly their energy pOUl' into managing waiting lists
can be done, because others have done it. own values and goals in the context of and enforcing rules of access. Patients
difficult treatment decisions. "Activated who fear that they will be denied care are
Aim 4: Reduce the Use of Unwanted often thereby induced to demand it, if
and Ineftective Medicai Procedures patients" encoUl'aged to ask questions and
to participate with theÍl' physicians in only to test for theÍl' own security. The
at the End of Life anger of someone denied access wastes
reaching the best plan of diagnosis and
Only a minority of patients, families, therapy often achieve better outcomes at time in apology, defense, and repaÍl'.
and clinicians support prolonged use of lower cost than patients in more passive Organizations and physician who find
life-sustaining procedures and dramatic modes. 67.68 Thi approach does not work new ways to minimize delays, produce
interventions in the terminal stages of for all patients, but it does for many, and continuous flows, and decrease waiting,
illness,52.53 yet substantial use ofthese pro- it challenges clinicians and organizations even while reSOUl'ces are more and more
cedures continues.iH In human terms, us- to develop new skills and processes for limited, will also find themselves devel-
ing unwanted procedures in terminal ill- interacting with patient . oping innovations that please patients
ness is a form of assault. In economic The financiaI gains are substantial. more while stressing and demoralizing
terms, it is waste. Several techniques, Prostatectomy candidates who actively caregivers less. The precondition to suc-
including advance clirectives55 and involve- help decide between medicaI and sur- cess is that caregivers suspend their clis-
ment of patients and families in decision gical treatment choose surgery as much belieflong enough to join wholeheartedly
making,56.57 have been shown to reduce as 50% less often than those for whom in trying out ways to reduce waiting un-
inappropriate care at the end of life, re- the physician alone makes the choice. 1m der conditions of severe reSOUl'ce con-
sulting in both lower cost and more hu- Diabetic patients coached by nonphysi- straint. Testing different ways to reduce
mane care from the patients' point ofview. cians to ask questions when they see 01' eliminate waiting may be ft'uitful in
lt is, of course, hard to know in ad- their physicians have lower glycohemo- appointment-scheduling systems, refer-
vance that this month 01' this week is the globin leveIs and higher functional sta- ral patterns, gatekeeping habits, and ad-
last month 01' week of a patient's life. tus than those who are not coached. 70 ministrative barriers to utilization. Sev-
That is, in fact, one of the main reasons Chronically ill adults who develop simpIe eral group practices have already had ex-
why this particular improvement chal- self-efficacy skills show subsequent citing successes with open-access primary
lenge rests squarely on the shoulders of medicaI utilization pattern 50% lower care systems in which the patient, not the
clinicians. lt requires OUl' highest skills to than matched controls. 71 system, chooses the exact appointment
help patients and familie balance the fac- date and time. A hospital committed to
tors ofuncertainty, clignity, risk, and re- reducing waits might refuse to delay ad-
ward involved in using meclical proce- Aim 7: Decrease Uninformative missions pending prospective certifica-
dUl'es appropriately as life ends. We must Waiting of Ali Types tion by payers, but guarantee repayment
begin by recognizing that today the ap- In health care, experienced physicians of any charges from admissions that are
propriate balance is badly missing. sometimes use "watchfu1 waiting" to gain decertified after the facto
information and to allow natUl'al healing
Aim 5: Adopt Simplified Formularies to proceed. This is a sound strategy, Aim 8: Reduce Inventory Leveis
and Streamline Pharmaceutical Use often preferable to aggressive clinicai Other industries have dramatically re-
This aim applies e pecially for anti- intervention. However, a large propor- duced their inventory leveis through the
biotics and for drug prescriptions for tion of the waiting that occurs in health u e of "just-in-time" process flows, im-
the elderly and chronically ill. Medica- care is not of this informative type; it proved supplier management, and pro-
tion prescribing elTors,óll,5!l overuse of adds no value for either the caregiver 01' cess simplification.72 By comparison,
antibiotics 60 (especially broad-spectrum the consumer of care. In fact, rapid ac- health care organizations maintain high
antibiotics), and inappropriate polyphar- cess and high responsiveness are among inventory leveIs and tend to underuse
macy in the elderly and chronically the major quality characteristics desired capital equipment. 75.n
illUl ,52 are well documented. Simplified by the beneficiaries ofhealth care. 72 Mod- At first glance, inventory alone may
formularies and educational interven- ern companies outside the health care seem to explain so little ofthe cost struc-
tions among cliniciansl' 1•64 lead to safer system devote a great deal of attention ture of health care that its reduction
and less expensive prescribing practices. to reducing such waits throughout the would not be a significant gain; but look
In addition, simplifying the processes chain of production of a product 01' ser- again. Inventory recluction to 10% of
by which we order, prepare, and deliver vice. They aim for continuous flow; they historicallevels, which other industries
meclications should reduce errar rates. reject batching in favor of more agile, have achieved, saves money in obvious
One hospital system has reported re- stream1ined manufacturing processes.7:l ways by ft'eeing capital, decreasing stor-
current annual savings of nearly $1 mil- Constructing feasible wait-ft'ee pro- age space, and simplifying record keep-
lion by using simple ways to ensure the cesses under constrained reSOUl'ces de- ing, for example. However, in less ob-
timely administration of correct peri- mand high leveis of process redesign vious and even more important ways, a
operative prophylactic antibiotics. 65 and invention, but it lead to markedly system that can minimize it own in-
This aim is given special Ul'gency by improved quality at much lower cost. ventory leveis may well be fundamen-
the early warnings we now have about In the buffeted health care economy, tally less expensive to manage and more
new strains of organisms resistant to with wholesale budget cuts now common, adaptive to changing needs. If we must
multiple antibiotics. 60•56 The wisest pos- more waiting may appear to be inevi- tore 1000 copies of a form, because we
sible use of antibiotics may help to slow table as a device for rationing scarce ser- cannot be sure that one will be delivered
the emergence of resistance. vices. 74 The vocabulary of limitation be- when we need it, we must either throw

JAMA, September 14, 1994-Vol 272, No. 10 Aims for Health System Reform-Berwick 799
away 01' use up our stocks when we neeel saveel almost $1 million per year while weU justified by the savings in both time
a new version. A system that coulel ele- improving functional status outcomes for and money. An automated medicaI recorel
Iiver forms to us reliably, exactly when total hip replacement patients (M. Weeel, may provicle a pmtial solution, but it will
neeeleel, woulel by its nature have to be written communication, February 1994). be little help if it merely stores magneti-
in c10se communication with us anel The key point is that physician anel cally the waste formerly stored on papel'.
thereby better able to unelerstanel our nW'ses themselves must unelerstanel anel
neeels anel more Iikely to change quickly drive this movement towm'elreeluceel com- Aim 10: Reduce the Total Supply
when necessary. plexity anel lower inventory. Simplifica- of High-Technology Medicai
What elo physicians have to elo with so tion wiU make the most sense not when and Surgical Care and
aelministrative a matter as inventory lev- thrust on them, but when sought anel Consolidate High-Technology
eIs? A great eleal. By stanelarelizing their planneel with anel by them. What applies Services Into Regional and
requests for materiaIs anel services, anel to hip prostheses applies equally well to Community-wide Centers
by taking the time to explain their neeels many types ofelwable meelical equipment, The largest single eleterminant ofthe
carefully to their suppliers, physicians consumable supplies, examining room rate of high-technology care anel inva-
can help smooth the flow of supplies stocks anel elesigns, papel' forms, anel pro- sive proceelures is the leveI of local sup-
through their own system of work anel, ceelw'e-manual specifications. In a gl'OUp ply of those services,tI.XH"; For many
as a happy by-proeluct, reeluce both waits of eight peeliatrician " how many types of high-technology practices, reduction in
anel waste. standing orelen; shoulel there be accorel- the total supply is an effective and safe
Take, for example, the inventory ofhip ing to which the support staff prepm'e a way to reeluce costs and limit aelverse,
prostheses in an Olthopeclic unit. Imag- toelcUer for examination? The common an- meelically ineluceel outcomes.
ine that eight surgeons in a group ele- swer is, "Eight." The correct answer if When this reeluction is achieveel
manel that a total of a elozen elifferent we truly value both quality anel efficiency through con olielation, we can expect out-
prostheses be available. To have suffi- is, "One." comes to improve. Encouraging elata sug-
cient back up stocks ofprostheses on hanel, gest a positive relationship between "vol-
the purchasing office must maintain 12 Aim 9: Record Only Useful ume" and "outcomes," especially with re-
processes for orelering anel storage--one Information Only Once gm'el to high-technology services, although
per prosthesis type. The purchasing Let us define "useful" as "Iikely to be the ful! profile of this l'elationship is not
office must manage multipIe outsiele used by someone, sometime." By this yet known.N-X~ Duplication ofservices re-
supplier contracts with attenelant legal, measure, medicaI recorels, aelministrative suIts in higher costs, higher use mtes,
accounting, anel clerical costs. The oper- habits, anel regulatory history require anel inefficient use of capital. Some ben-
ating room central supply service must extraorelinary leveIs of"useless"-waste- efits from regional consolidation have been
maintain a complex storage anel retrieval fuI, eluplicative, anel unused-record keep- elocumented for cm'e of very low-birth-
system so that Dl' Jones always receives ing, both clinicaI and aelministrative.'''''-'l weight infants!JO anel for aelult cm'eliac sw'-
his proper tray anel Dl' Smith, hers. If Decreasing eluplicate elata entry anel ceas- gery.91 Most metropolitan m'eas in the
there are 10 technicians in central supply, ing the recoreling of information that is United States should reduce the number
each of whom must be traineel in the pre- never used woulel both reeluce costs anel of centers engaging in careliac sw'gery,
fen'eel setup for each of the 12 prosthe- improve cm·e. To accomplish this goal re- high-risk obstetrics, neonatal intensive
ses, then 120 prosthesis-technician elyaels quil'es rational changes in l'egulation anel, cm'e, organ transplantation, tertiary can-
existo Even if each elyael functions per- even more important, changes in out- cer care, high-Ievel trauma cm'e, anel high-
fectly with 99% probability, the probabil- moeleel habits and information manage- technology imaging.
ity of systemic perfection (ali 120 elyaels ment systems. Some changes may be out- This is not an easy change for physi-
correct) is approximately 0.99 120 01' 0.30. siele the jW'iseliction of physicians anel cians to accept. Some physicians in high-
(This is the joint probability of 120 inele- nw'ses, but many useless habits are pre- technology specialties willlose income and
penelent events ali occurring together if served by aelministrative fiat 01' by in- job OPPOltunities as a resulto For-profit,
each has a 99% chance of occw·ring.) ternaI governance committees on forms entreprenew'ial provielers of meclical im-
Compare this system with one in anel meelical recorels. In ali m'enas, nurs- aging, renal elialysis, and outpatient sw'-
which eight sW'geons agree, through con- ing anel physician leaelers shoulel insist on gery, for example, may finel their busi-
versation, research, anel compromise, to rational parsimony anel shoulel eliscm'elre- ness oppOltw'Úties constraineel. It wiil be
elemanel only three prostheses in stock coreling practices honoreel by time but necessal'Y for other physicians, who see
insteael of 12. Inventory e1ecreases, as not by logic. How often elo we recorel vital the benefits of consolielation of services,
elo the costs of accounting, contracting, signs anel why? Why cio separate sections to insist on sensible regionalization none-
storage, tracing, anel staff training. of the medicaI record contain virtually theless, even at the risk of internaI pro-
Higher-volume purchases from a single the same information? How many times fessional conÍlicts, Com'age in meelicine
supplier will earn price breaks for the do patients have to teU us their telephone now inclueles the courage not to elemanel
hospital. Insteael of 120 prosthesis-tech- numbers? Do we record quantitative in- the highest leveI oftechnology "right here,
nician elyaels to maintain, there are now formation in claunting tables or in infor- on site," but to seek insteael the more
only 30, anel the probability that ali will mative gl'aphs? Simply substituting challenging forms of integrateel, intel1n-
function correctly is 0.99'JO 01' 0.74, a250% graphs for tables anellists of numbers in stitutional relationship that, in the long
improvement. The reeluceel complexity our meelical recorels woulel be a big step run, achieve more for less.
also creates the oppol'tunity to learn forward.
more quickly about the outcomes fi'om As they seek simplifiecl and less waste- Aim 11: Reduce the Racial Gap in
the chosen prostheses (it is easier to fulrecord keeping, clinicians shoulcl ques- Health Status Beginning With Infant
stuely three than 12 in a single ortho- tion the ever-present, intimidating trump Mortality and Low Birth Weight
peelic unit), setting the stage for scien- cm'cI of "medicaI-legaI requirements." Extreme elifferences remain in the in-
tifically informeel changes in the future Some of these requil'ements m'e indeed fant morbielity anel mortality rates for
selection of prostheses. By exactly this wOlth wOl'rying about, but many m'e minorities anel low-income populations
change (reelucing the numbel' ofhip pros- myths-Dw'able but Wl'ong. In some compm'eel with whites ofhigher economic
theses in use), one hospital system has cases, the risks of nomecording may be status in the Uniteel States.~t.!l:; The

800 JAMA, September 14. 1994-Vol 272, No. 10 Alms for Health System Reform-Berwick
causes are multifactorial,!>l anel so mul- between white anel minority health sta- :{027 -:~O:{O.
tiple system improvements ",'iU be re- :lo Farrow DC, Hunt WC. Samet JM. Geographic
tus woulel begin to c1ose. Patients woulel \'ariation in the tl'eatment 01' localized breast can-
quireel to reduce the gap. repOlt shorter waiting times, more re- cer. X ElIg/ ./ Med. 1992::{26:1097-1101.
Perinatal outcomes are only the tip of spectfu1 dialogues with theu' health cm'e ~. Lazo\'ich D. White E. Thomas DB. Moe RE.
the iceberg of social inequity in the health provielers, anel less duplicative anel elis- Undenttilization 01' bl'east-conset'\'ing surgery and
status ofAmerican .!';'!l7 ot only are black organizeel cm'e. In short, such a system of radiation thel'apy among \\'omcn \\ilh slage I OI' [1
breast cancer. .} rUIA. 1991 ;2()(j::{.I:3:~-:'W38.
infants 240% more likely than whites to cm'e woulel be better, cheaper, and inci- 5. Nattinger AB. Gottlieb M, . Veun J. Yahnke D.
die in the perinatal perioel, but they also elentaUy more satisfying to \Vork ",'ithin. Good\\in .JS. Geographic \'<u'iation in the use 01'
face a far more uncertain futul'e if they A gooel case exists for other aims as bl'east-consen'ing treatment 1'01' bl'east cancel'.
live. A black male bom toelay in the Uniteel weU, but the real point i . for physicians X ElIg/ .} Med. 1992;:326:1102-1107.
6. Wennbel'gJE. Mulley AG.JI'. Hanley O, eta1. An
States has the foUowing exces risks of to get starteel anel to engage in improving assessmenl 01' jll'Ostatectomy for benign ul'in31'y
eleath compared with a white male: 150% specific dimensions of care as quick1y as tract infection: geographic val'iations and the evalu-
for hemt clisease, 190% for stroke, 280% we cano Physicians who wish to help leael alion 01' medicai cal'e outcomes. .} AM A. 1988:259:
8027-:~0:{0.
for renal elisease, 340% for human immu- systemic change towarel aims like these 7. Winslow CM. Solomon DH. Chassin MR, et aI.
nodeficiency vim -relateel eleath, anel wiUlikely have to cultivate new personal The appl'opl'ialeness of carotid endmtel'eClomy.
680% for homicide.!JS Life expectancy for skills. To accomplish each of these im- X Eug/.] .lfed. 19 ';31 :721-727.
a black male at birth toelay is 8 yem . less provements, the heroic image ofinelivielu- . Winslow eM, Kosecoff.J B. Chassin 1\1. Kanouse
than for a white male; for a black female, alist physicians each doing the best he OI' DE. Brook RH. The apPl'opriateness ofperforming
coronar~' altcl'y b~l)aSS surgery. .]rLUA. 19 ;260:
it i 6 years lessY' she can anel each bem1ng fuU anel per- 505-.'iOH.
These eliscrepancies are not only of- sonal responsibility for the care of the 9. Deyo RA. Fads in the treatment of 10\\' back
fen ive, they are insupportable. Any na- patient cannot possibly suffice. These aim pain. ,V EII{J/ ./ J/ed. 1991:325:1039-1040.
reflect the performance of system . of in- 10. Bernstein s.J. McGlynn EA. Siu AL. et aI. The
tional OI' regional changes worth caUing appropriatenes~ 01' hysterectom,V: a comparison 01'
"reform" in health care, any agenela terelepenelency, not of inelividuals acting care in se\'en health plans. .] AM A. 199:{:269:2398-
worth caUing "improvement," must in- alone. They wiU be accomplisheel by those 2402.
tend explicitly to reeluce this injustice. who proviele health care, 01' they will not 11. Kahn KL, KosecoffJ, Chassin M. Solomon DH.
Infant mortality anellow birth weight be accomplisheel at alI. Physicians who Bl'ook R H. The use and misuse 01' upper gastroin-
testinal endoscopy. Aun In/em Med. 1988;109:6&:1-
is a fine place to begin. The potential wish to help must lem'n more than how to 670.
gains are large, the measurement sys- heal patients, they must lem'n how to heal 12. Soumerai SB. Salem-Schatz S. A\'ol'l1 J. Cas-
tems to support tests of change are fea- system. leris CS. Ross-Degnin D. Popo\'sky 1\1A. A con-
sible, and the implications for cost, as Healing systems ",,'iU require skills not trolled bial 01' edllC<ltional outreach to improve blood
transfusion pl·actice. .]rLU A. 1993;270:961-966.
weU as for outcomes, are favorable. Re- customm'ily taught in meclical training. 13. Crain EF. Bulas D. Bijllr PE. Goldman HS.
sults "viU come only from highly inte- Progre 'ive meelical eelucation in the fu- Chest x-rays at'e often unnecessm'y in febrile neo-
gI'ated, coUaborative action at the com- tW'e shoulel help physicians, nurses, and nates. Pedia/1'Ícs. 1991; :821-824.
1~. E\\igman BG. Crane JP. Frigoletto FD, et aI.
munity levei, anel solutions wiU vary administrators participate fuUy in chang-
Effect of prenalal lllt!'asound sCl'eening on perina-
ba eel on local conditions. Meelicalleael- ing the systems in which they do theu' tal olltcome. N EII{J/ .] Med. 1993;:~29:821-827.
ership of this community-wiele activity work. Relevant skills incluele the fol!ow- 15. Chassin MR, Kosecoff .J. Pal'k RE, et aI. Does
is essential, notjust to ensure that health ing: the ability to understanel the health inapPl'opriate use explain geog!'aph.ic val'iations in
care organization allocate their 0W11re- care system as a whole, not merely one's the use 01' heallh care services'! a study 01' three
pl'Ocerlures. .] AMri. 1987;258:2533-2537.
sources where they will do the most own profession; the ability to gather anel 16. Bl'Ook RH. Park RE. Chassin MR. Solomon
good, but also to stimulate the conscience interpret elata on outcomes of cm'e; the DH. Keesey .J. Kosecoff J. Pt'eclicting the appro-
of the public and to convene organiza- ability to work eEfectiyely acro's elis- priate use 01' carotid endarterectomy, upper gas-
tion and indivieluals in pursuit of com- plinary bounelm'ies anel, when neeeled, to tt'ointestinal endoscopy. and coronary angiography.
X Eng/ .] Med. 1990::32-3:1173-1177.
mon goals. The increasing investment pmticipate in fonTIal ÍlTIprovement teams; 17. Leape LL, Park RE. olomon DH. Chassin
in severe competition in many local medi- the ability to tmst generaUy in the mo- MR. Kosecoff.J. Brook RH. Does inappl'Optiate use
caI markets will prevent such col!abo- tives anel intelligence of people of eliffer- explain small-aI'ea \'ariations in lhe use of health
rative action unless clinicaI leaelers, ent professional roles, geneler, anel life care sen'ices? .]A,llA. 1990;263:669-672.
18. Franks P, Clancy CM, , utting PA. Gatekeep-
driven by their ethical duty, insist on it. experience; the skill anel willingTIess to ing re\'isiterl: protecting palients fl'Om o\'ertreat-
test new approaches to work instead of ment. N Eng/ .] Med. 1992;:{27:424--129.
CONCLUSIONS clinging to the status quo as the safest 19. Friedman B, Elixhallsel' A. Increased use ofan
option; anel the ability to interpret the expensive, elective pl'Oceclure: total hip replace-
These 11 aims define an action plan for ments in lhe 1980's. Med Ca/·e. Hl93;:{1:581-599.
clinicians who wish to leael effective unelerlyi.ng neeels of patients anel others 20. Einstadler D. Kent DL. F'ihn SD. Deyo RA.
change in US health cm'e. Any hospital, who elepenel on physicians, so the elefini- Variation in the !'ate 01' cervical spine sUl'gery in
integrateel system, 01' community that tion of "needeel il11provements" ",riU be Washington Slate. .lled Care. 19~)3::H:711-718.
made substantial gains in even half of placeel firm1y in the hanel of those who 21. WennbergJE, Fl'eemanJL. Culp WJ. Are hos-
pital sen'ices I'ationed in Te\\" Haven 01' overuti-
these m'eas woulel be easily distinguish- are served by the health care system?' lizerl in Boston? LanceI. 19 7:1:11 5-11 .
able in cost, outcome, and satisfaction. "Reform" seem so confusing, The 22. Grinel' PF. Glaset· lU. Misuse of laboratol"\'
Co ts would elecrease dramaticaUy as a frenzy invites a sense of helplessness, tests and diagnostic procedures. N Eug/ .] ,]feei.
1982:307:1:~:~(j-l:{39.
result of decreases in inappropriate and but we need not feel helpless. Clinicians 23. Axt-Adam P, \'an der WoudenJC. \'an der' Does
unwanted care, simplified pharmaceuti- who do not wish to feel victimized shoulel E. Inflllencing beha\'iOl' ofphysicians ordering labo-
cal use, less supply-ell'iven use ofmeelical specify the improvements they intend /'ato/''v te~ts: a Iitel'ature stud,V. Med Cal'e. 1998;
proceelures, reeluceelrecord keeping, anel to initiate to help better meet social :31:7H4-794.
2~. Kosecoff.J, Chassin MR. F'ink A, et aI. Obtaining
less complex inventory. Health status in- neeels anel then shoulel welcome changes
clinicai dat.a on lhe appl'Opl'iateness of medicaI care
elicators woulel reveal elecreases in pre- in pursuit of those improvements. in community pl'actice. ']rLI/A. 19,7:258:25.38-2542.
ventable morbidity anel mOltality, more References
25. Weingm-ten S, Agocs L. Tankel N. et aI. Re-
inclivielualized patient care elecisions, anel dllcing lengths ofstay for patients hospitalized with
1. Bel'l.-ick DlH. Continuous impro\'ement as an chest pain using medicaI practice guidelines and
fewer complications of clmgs, invasive ideal in hcallh cal'e. X ElIg/ .} Med. 1989;:~20:5={-5(i. opinion leaders. rim .] Cal'dio/. 199:{:71:259-262.
tests, anel sw'gica1 procedmes, ]f com- 2. Bl'ook RH. Practicc guidelines and practicing 26. Adams MM. Bl'Ogan DJ. Kendrick JS. et aI.
munity-wiele action were taken, the gaps medicine: are lhey compalible" hLllA 19,9:262: Smoking. pregnancy. and sOIll'ce 01' prenatal care:

JAMA. September 14, 1994-Vol 272, No. 10 Alms for Health System Reform-Berwick 801
..esults f..om the Pl'egnancy Risk Assessment Moni, 51. Flamm BL, Newman LA, Thomas SJ, et ai. Med. 1993;328:772-778.
to..ing System. Obstet Gynecol. 1992;80:738-744. Vaginal biJth afte.. cesal'ean delivery: re ults of a 76. Thol'pe KE. lnside the black box of adminis-
27. Chilmonczyk BA, Salmun LM, Megathlin K , 5-yea.. multicentel' collabol'ative study. Obstei Gy- tl'ative costs. Hea/lh Aff(Millwood}. 1992;11:41-55.
et aI. Association between exposul'e to envil'on- nerol. 1990;76:750-754. 77. Woolhandler S, Himmelstein DU. The detelio-
mental tobacco smoke and exacerbations of asthma 52. GarrettJM, Harl'is RP, No..burnJK,etal. Life- l'ating administl'ative efficiency of the US health
in child..en. N Engl J Med. 1993;328:1665-1669. sustaining t..eatments during te..minal illness: who cal'e system. N EngL J Med. 1991;324:1253-1258.
28. Higgins MW, EnrightPL, K..onmal RA, Schen- wants what? J Gen Inlel1l Med. 1993;8:361-368. 78. Woolh,mdleI'S, Himmelstein DU, LewontinJP.
ke.. MB, Anton-Culve.. H, Lyle M, fo.. the Ca..- 53. G..ay WA, Capone RJ, Most AS. nsuccessful Administrative costs in US hospitais. N EJlgI J
diovascuJa.. Health Study Reseal'ch Group. Smok- eme"gency medicai ..esuscitation: are continued Med. 1993;329:400-403.
ing and lung function in elde..ly men and women: efforts in the emergency department justified? 79. Institute of Medicine. Tl1e Complller-Based Pa,
the Cardiovasculal' Health Study. J AMA. 1993;269: N Engl J Med. 1991;325:139:3-1398. lienl Record: AJl Esse-n/ial Teclmology fOI' Healtl1
2741-2748. 54. LlIbitz JD, Riley GF. Trends in lIledical'e pay- Care. Washington, DC: Nationa.! Academy Pre ;1991.
29. Janel~ch DT, Thompson WD, Va..ela LR, et aI. ments in the last year of life. N Engl J Med. 1993; 80. Weed LL. Medicai records thatguideand teach.
Lung cancer and exposure to tobacco smoke in the :328: 1092-1 096. N Ellg1 J Med. 1968;278:593-600,652-657.
household. N Engl J Med. 1990;323:632-636. 55, Emanuel LL, Ba,','y MJ, StoeckleJD, Ettelson 81. Gl'eenfield S, Nelson EC, ZubkoffM, et aI. Vma-
30. SchoendOlf KC, Kiely JL. Relationship ofsudden LM, Emanuel EJ. Advance dil'ectives for medicaI tions in resoul'ce utilization among medicai special-
infant death syndrome to matel'l1a! smoking dLUing care: a case for greater use. N EJlgl J Med. 1991; ties and systems of cal'e: results [rom the Medicai
and afte.. p..egnancy. Pediatl·ies. 1992;90:905-908. 324: 9-895. Outcomes Study. JAMA. 1992;267:1624-1630.
31. Seidman DS, Ever-Hadani P, Gale R, et aI. 56. Townsend J, F'l'ank AO, Fremont D, et ai, Ter- 82. Schl'oeder SA, Sandy LG. Specialty distribu-
Effect of maternal smoking and age on congenital mina.! cancer CaI'e and patients' preference for place tion of US physicians: the invisible (h~ve.. ofhealth
anomalie . Obstet Gyneeol. 1990;76:1046-1050. ofdeath: a prospectivestudy. BMJ. 1990;:301:415-417. cal'e costs, EJlgl J Med. 1993;328:961-963.
32. Kelle..mann AL, Rivara FP, Somes G, et ai. 57. SmediJ'a G, Evans B, Grais L, et ai. With- 3. Welch WP, Miller ME, Welch HG, Fisher ES.
Suicide in the home in l'elation to gun owne..ship, holding and \\~thdrawal of life support fi'om the Wennberg JE. GeogJ'aphic vlll~ation in expendi-
N Engl J Med. 1992;327:467-472. clitically iII. N Engl J Med. 1990;322:309-315. tu,'es for physicians' services in the United States.
33. Kelle..mann AL, Rival'a FP, RushfOlth NB, et 58. German PS, BUlton LC. Medication and the N Engl J Med. 1993;328:621-627.
aI. Gun ownership as a l~sk facto .. for homicide in elderly: issues of pl'escription and use. J Aging 84. Every NR, Larson EB, Litwin PE, et aI. The
the home. N Engl J Med. 1993;329:1084-1091. Health. 1989;1:5. association between on-site CaI'diac cathetel'ization
34. Koop CE, Lundbe..g GD. Violence in Amel~ca: 59. Lipton HL, Bird J A. DIUg utilization I'eview in facilities and the use of cOl'Onal'y angiogJ'aphy after
a public health eme..gency; time to bite the bullet ambulatol'Y settings: state of the science and di- acute myocal'dial infm'ction. N Engl J Med. 199:3:
back. J AMA. 1992;267:3075-3076. Co....ections: rections for outcomes reseal'ch. Med Care. 1993; 329:546-551.
JAMA. 1992;268:3074; JAMA. 1994;271:1404. 31:1069-1082. 85. Farber BF, Kaiser DL, Wenzel RP. Relation
35. Loftin C, McDowall D, Wiel'Sema B, Cottey TJ. 60. Cohen ML. Epidemiology of drug resistance: between surgical volume :U1d incidence of postop-
Effects of ..estl~ctive licensing of handguns on ho- implications for a post-antimicrobial era. Science. erative wound infection. N Engl J Med. 1981;305:
micide and suicide in the District of Columbia. 1992;257:1050-1055. 200-204.
N Engl J Med. 1991;325:1615-1620. 61. Bernstein LR, Folkman S, Lazatus RS. Chat·- 86. Flood AB, Scott WR, Ewy W. Does pl'actice
36. Centers for Disease Cont..ol. Fatal injul'ies to acteristics 01' the use and misllse of medications by make perfect? the relation between hospital vol-
child..en: United States, 1986. MMWR Morb MoI" an eldel'ly, ambulatol'Y population. Med Care. 1989; ume and outcomes for selected diagno tic catego-
tal Wkly Rep. 1990;39:442-445. 27:654-663. Iies. Med Care. 1984;22:9 -114.
37. Chorba TL, Klein TM. Inc..eases in c..ash in- 62. LesarTS, Bliceland LL, DelcoUl'e K. Pa..malee 87. Laffel GL, BaI"TIett AJ, Finkelstein S, Kaye MP.
\'olvement and fatalities among motor vehicle oc- JC, Masta-Gornic V, Pohl H. Medication presCl~b­ The relation between expel~ence and outcome in healt
cupants younge.. than 5 yeal'S old. Pediatrics. 1993; ing eITOI'S in a teaching hospital. J AMA. 1990;263: t'1U1splantation. N Eng/ J Med. 1992:327:1220-1225.
91:897-901. 2329-2334. 8. Luft HS, Bunker JP, Enthoven AC. Should
38. Thompson RS, Thompson DC, Rivara FP, 63. Avorn J. Soumerai SE. I mpro\~ng dlug-thel'apy operations be regionalized? the empilical I'elation
Salazar AA. Cost-effectiveness analysis of bicycle decisions through educational outreach: a ..andom- between surgical volume and mOltality. N Engl J
helmet subsidies in a defined population. Pediat- ized controlled trial of academically based 'detail- Med. 1979;301:1364-1369.
l'iC8. 1993;91:902-907. ing: N Engl J Med. 1983;308:1457-1463. 89. Luft HS, Hunt SS, Maerki SC. The volume-
39. Centers fo .. Disease Cont..ol. AJcohol-..elated 64. Kimbedin CL, Bernardo DH, Pendergast JF, outcome relationship: p..actice-makes-perfect OI' se-
traffic fatalities during holidays: United State ,1989. McKenzie LC. Effects of an education program for lective refelTal patterns? Hea/lh SeI,' Res. 1987;
MMIVR Morb MOl-ta/ WkLy Rep. 1989;38:861-863. commllnity phal'macists on detecting dl'ug-..elated 22:158-182.
40. Phibbs CS, Bateman DA, chwaltz RM. The problems in elderly patients. Med Care. 1993;31: 90. Boyle MH, TommceGW, inclairJC, HOI'\\'ood
neonataJ costs of maternal cocaine use. J AMA. 1991; 451-468. SP. Economic evaluation of neonatal intensi\'e cal'e
266:1521-1526. 65, Classen OC, E\'ans S, Pe totnik SL, Horn SD, of very-Iow-bilth-weight infants. N Eugl J Med.
41. FI~esJF, Koop CE, Beadle CE, etal. Reducing Menlove RL, Burke JP. The timing of pl'ophylactic 1983;30 :1330-1337.
health care costs by ..educing the need and demand administ"ation of antibiotics and the lisk of sllrgical 91. Showstack JA, Rosenfeld KE, Gal11ick DW,
fOI' medicaI sel'\'ices. N EngL J Med. 1993;329:321- wound infection. N Engl J Med. 1992:326:281-286. Luft HS, Schaffarzick RW, Fowles J. Association of
325. 66. Neu HC. The cJisis in antibiotic resistance. Sei, volume with outcome of cOl'onm'y arte,'y bypass
42. US Dept 01' Health and Human Services, US ence. 1992:257:1064-1073. gl'aft sUl'gel',Y: scheduled vs nonscheduled opera-
Public Health Sel'vice. Healthy People .2000: Na- 67. Wennberg JE. Impl'oving the decision-making tions. JAMA. 1987;257:785-789.
tional Health Pl'Olnotion and Disease Prevenlioll pl·ocess. Hea/lh A/f (Millll'ood). 1988:7:99-106. 92, Centel's for Oisease Control. Low bitthweight:
Objec/ives. Washington, DC: US Oept of Health 68. Greenfield S, Kaplan SH, Wal'eJEJr. Expand- United State , 1975-1987. MMWR MOI'b MOl-tal
and Human Services; 1990. ing patient involvement in care: effects on patient Wkly Rep. 1990;39:148-151.
43. McGinnisJM, Foege WH. Actual causes ofdeath outcomes. Anu lutem Med. 1985;102:520-528, 93. WegJnan ME. Annual summary of vital statis-
in the United States. JAMA. 1993;270:2207-2212. 69. Kaspel' JF, Mulley AG, Wennberg JE. Devel- tics. Pediatrics. 1993;92:743-754.
44. Centers for Disease Control and Prevention. oping shared decision-making progJ'ams to improve 94. Kempe A, Wise PH. Bal'kan SE, et aI. ClinicaI
Yeal'S of potential life lost befOl'e age 65: United quality of health cal'e. QRB Qnal Rev Bul/. 1992; detel'minants o[ the racial displll~ty in very low
States, 1990 and 1991. MMIVR Morb Morlal Wkly 18:183-190. bil'th weighl. N Engl J Med. 1992;327:969-973.
Rep. 1993;42:251-253. 70. Greenfield S, Kaplan S, Ware JE, et aI. Patient 95. GUl'alnick JM, Land KC, Blazer DB, Fillen-
45. US P,'eventive Se..vices Task FOI'ce. Gnide lo pa'ticipation in medicai cal'e: effects on blood sugar baum GG, Branch LG. Educational status and ac-
Clinicai Preventive Serviees: An AssessmeJlI oflhe contl'ol and quality of life in diabetes. J Gell Intem tive life expectancy among older blacks and whites.
Effectiveness of 169 Interventions. Baltimo..e, Md: Med. 1988;3:448-457. N Engl J Med. 1993;329:110-116.
WilIiams & Wilkins; 1989. 71. Sobel OS. Mind mattel's, money mattel'S: the 96. SommeJ' A, Tielsch JM, Katz J, et aI. Racial
46. Roessner J. 'The healthiest place in AmeJ~ca: cost-effecti\'eness of clinicaI beha\'ioral medicine. differences in cause-specific pl'evalence of blind-
Qual Connecliol/.~. 1993;2:10-11. In: 1I1el/lal Medicine Up(/ale: Special Repor/. Los ness in East Baltimore. N Eugl J Med. 1991;325:
H. BottomsSF. Rosen MG,Sokol RJ. The incl'ease Altos, Calif: The Centel' for Health Sciences; 1993. 1412-1417.
in the cesal'ean bilth rate. N Engl J Med. 1980; 72. Ware JE, Snydel' MK. Dimensions of patient 97, Pappas G, Queen S, Hadden W, Fisher G. The
302:559-563. attitudes regarcling doctors and medicai CaI'e sel'- increasing disparity in mOltality between sociode-
48, Cente,'S for Disease Control and Pl'evention. vices. Med Care. 1975;13:669-682. mOgJ'aphic gl'OUPS in the United States, 1960 and
Rates of cesal'ean delivery: United States, 1991. 73, Womack JP, Jones DT, Roos D. The Machine 1986. N Engl J Med. 1993;329:103-109.
MMWR Morb M011al Wkly Rep. 1993;42:285-289. Thal Changed lhe World. New York, NY: Harpel' 98, Centers fo.. Disease Control. Yeal'S of potential
49. Rockenschaub A. TechnoJogy-f..ee obstetrics at Perennial: 1991. life lost before age 65, by race, Hispanic origin, and
the Semmelweis Clinic. Lancet. 1990;335:977-978. 74. Gl'umet GW. Health cm'e rationing through in- sexo United States, 1986-19 . MMWR Morb Mor-
50. Lopez-Zeno JA, Peaceman AM, Adashek JA, convenience: the third palty's secl'et weapon. lal Wkly Rep. 1992;41(suppl SS6):1 -19.
Socol ML. A contl'oUed tria! of a pl'ogram for the • Engl J Med. 19 9;:321:607-611. 99, Ber\\~ck DM, Enthoven A, Bunker JP. Quality
active management of labor, N Engl J Med. 1992; 75. Redelmeiel' DA, Fuchs VR. Hospital ex pendi- management in the HS: the doctol"s role. BMJ.
326:450-454. tUl'es in the nited States anel Canada. N Engl J 1992;304:235-239.304-308.

802 JAMA, September 14, 1994-Vol 272, No. 10 Aims for Health Syslem Reform-Berwick

S-ar putea să vă placă și