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Highlights Company Profile

The first body contouring solution to combine safety with effectiveness UltraShape, founded in 2000, develops, manufactures and markets innovative, non-invasive
An average reduction of two centimeters in body circumference after a single treatment solutions for the aesthetic medical field. The UltraShape expert team of scientists is dedicated to the
Lysed adipose tissue cleared via the body's natural mechanisms development of cutting edge body contouring technology that enhances patients' self image and
Tracking and guidance system ensures homogeneous treatment sense of well being.

Non-invasive, focused ultrasound technology First to market - UltraShape offers a unique technology that positions the company as the pioneer
Long-term reduction of fat cell population through mechanical effects in non-invasive body contouring. The revolutionary UltraShape Contour I is the first computer guided
Selective emulsification of adipose tissue, leaving neighboring tissues unharmed non-invasive body contouring system to emulsify fat cells selectively using focused ultrasound
technology.
A measurable difference to more patients' lives
UltraShape Inc. was established in Delaware by Ami Glicksman M.D., formerly a senior plastic surgeon
“Walk-in, walk-out” office based treatment
at the Sheba Medical Center, Tel Aviv, and Yoram Eshel, Ph.D, MBA, a leading expert in medical
An effective option when surgery is not desired
physics with fifteen years experience in high power ultrasound technology. UltraShape Ltd. operates
No disruption to patients’ daily routine
through its fully owned subsidiary in Israel.
No downtime and no need for maintenance treatment
The company adheres to the highest scientific and quality standards. UltraShape is ISO 13485: 2003 certified.

DBR-10004 Rev. C
Before treatment After two treatments System Components
Transducer:
Delivers the focused ultrasonic beam
Provides real-time feedback on acoustic contact
System Console:
Comprised of the ultrasound generator, power unit, cooling system and system computer
Courtesy of: C. Inglefield, M.D., BSc, London, UK Stand:
Illumination system and tracking system based on a single video camera
System display screen and control panel

Before treatment After a single treatment

Specifications
Technology Focused ultrasound
Key Standards IEC 60601-1, IEC 60601-1-2, IEC 60601-1-4, UL60601-1, CSA 22.2
Certifications CE Mark, CSA, CB Scheme
Acoustic output ISPTA= 17.5 W/cm2
Ultrasound operation frequency 200± 30KHz
Courtesy of: P. Heden, M.D., Stockholm, Sweden Input voltage 100, 115, 200, 230V, 50-60 Hz, factory set
Dimensions Where Safety and Effectiveness Finally Meet
Cabinet (HxLxW) 0.65 x 1.15 x 0.55 meters
Light Stand (Height) 2.2 meters
Before treatment After a single treatment Weight
Cabinet & light stand 150 kg
Transducer 1.85 kg

List of Patents:
This product and its use are protected by one or more of
the following patents and/or pending patent applications:
US 6607498; US 20030083536 A1; US 20040106867 A1;
WO 02/054018; WO 04/00011
* Contour I is not yet available in the US
© 2006 UltraShape Ltd. All rights reserved.

Courtesy of: J. Burns, M.D., Dallas, TX, USA 30 Habarzel St., Tel Aviv 69710 Israel, Tel:+972-3-6457100 Fax:+972-3-6479321
0344 Toll free number: +800-22557252 info@ultrashape.com www.ultrashape.com
Combining Safety with Effectiveness Revolutionary Technology Convenience for You and Your Patients
The only solution to combine non-invasive treatment with measurable results The Contour I system is based on two proprietary technological innovations: A safe and simple “walk-in, walk-out” office-based

Safe clearance of lysed adipose tissue via the body's natural mechanisms Focused non-invasive ultrasound A non-invasive option when surgery is not desired
Treatment areas include abdomen, flanks and thighs
An average reduction of two centimeters in body circumference after a single treatment Tracking and guidance software
No downtime, no recuperation period and no maintenance
treatments
Minimal training with short learning curve
Clinical Results Non-Invasive Focused Ultrasound
The safety and effectiveness of Contour I is backed by The UltraShape technology is based on focused therapeutic
Contour I - The practical patient-friendly alternative
scientifically demonstrated results from multi-center clinical ultrasound which selectively lyses adipocytes. A predetermined
trials performed on hundreds of patients worldwide. amount of ultrasound energy is applied to the subcutaneous The UltraShape treatment is the first non-invasive body
Results include: fat layer where acoustic waves converge in a confined focal contouring solution to lyse fat cells safely and effectively in
volume causing mechanical disruption of fat cell membranes. both men and women. The treatment takes an average of
An average reduction of two centimeters in body
Since energy is delivered in pulses, there is no significant one and a half hours and is carried out in an office environment.
circumference following a single treatment
temperature elevation. Afterward, patients can immediately resume their daily
The majority of patients reported no pain or
Most importantly, the mechanical effect allows for tissue routines. Measurable results are evident after a single treatment.
discomfort during or following treatment
selectivity - only adipose cells within the targeted area are The option of additional treatments is available to individuals
Normal blood and urine profiles confirmed
disrupted while surrounding tissues including blood vessels, seeking enhanced results*.
physiologically manageable fat clearance
Histological and clinical evidence of selective nerves, and connective tissue remain unharmed.
damage to adipose tissue
An embedded ultrasound imaging system concurrently
No serious adverse effects
provides real-time feedback regarding acoustic contact. Contour I - Making a measurable
difference to more patients' lives
Fat Clearance Process
Advanced Tracking and Guidance Software Designed by plastic surgeons with physicians
Selective fat cell lysis takes place without causing damage to in mind, the UltraShape treatment is easily
neighboring blood vessels and nerves. Triglycerides from the The UltraShape treatment is guided by a real-time tracking and guidance system designed to guarantee administered by physicians or other healthcare
disrupted adipocyte cells are released into the interstitial fluid homogenous body contouring results. The system includes a software algorithm that maps the three professionals. Intended for the office
and gradually transported through the vascular system to the dimensional treatment zone. Precision and safety are reinforced by an optical image guidance device environment, it eliminates operating room
liver. The liver makes no distinction between fat originating which prevents treatment beyond the pre-marked zone and precludes repeat treatment. and anesthesia expenses. The system provides
from the disrupted adipocytes and fat derived from a consumed a user friendly, time-saving and cost effective
meal. The cell debris is removed through the physiological The tracking system addresses the dynamic nature of the treated area, a major challenge in body treatment platform that safely delivers a
pathways. contouring. As the patient breathes and moves, the fat being non-rigid, undergoes spatial deformities. measurable reduction in body circumference.
To overcome these obstacles, the system records and synchronizes the body's position in real-time, Patients who previously avoided invasive
enabling the patient to move freely or even get up during treatment. When the patient returns, the treatments will welcome this new body
system accurately resumes treatment. contouring option.

Ultrasound imaging transducer

Focused ultrasound therapeutic


Figure 1: Histopathological sample immediately
transducer
following the UltraShape treatment (Hematoxylin-
Eosin staining, x50). Image shows disrupted adipose
Low energy everywhere except
tissue with no damage to adjacent blood vessels. in the focal area

Figure 2: Histopathological sample immediately


following the UltraShape treatment (Hematoxylin-Eosin
staining, x25). Image shows damage only to fat cells * Still under clinical evaluation. Please refer to the
while skin and connective tissue remain unharmed. UltraShape website for the latest clinical updates.
Combining Safety with Effectiveness Revolutionary Technology Convenience for You and Your Patients
The only solution to combine non-invasive treatment with measurable results The Contour I system is based on two proprietary technological innovations: A safe and simple “walk-in, walk-out” office-based

Safe clearance of lysed adipose tissue via the body's natural mechanisms Focused non-invasive ultrasound A non-invasive option when surgery is not desired
Treatment areas include abdomen, flanks and thighs
An average reduction of two centimeters in body circumference after a single treatment Tracking and guidance software
No downtime, no recuperation period and no maintenance
treatments
Minimal training with short learning curve
Clinical Results Non-Invasive Focused Ultrasound
The safety and effectiveness of Contour I is backed by The UltraShape technology is based on focused therapeutic
Contour I - The practical patient-friendly alternative
scientifically demonstrated results from multi-center clinical ultrasound which selectively lyses adipocytes. A predetermined
trials performed on hundreds of patients worldwide. amount of ultrasound energy is applied to the subcutaneous The UltraShape treatment is the first non-invasive body
Results include: fat layer where acoustic waves converge in a confined focal contouring solution to lyse fat cells safely and effectively in
volume causing mechanical disruption of fat cell membranes. both men and women. The treatment takes an average of
An average reduction of two centimeters in body
Since energy is delivered in pulses, there is no significant one and a half hours and is carried out in an office environment.
circumference following a single treatment
temperature elevation. Afterward, patients can immediately resume their daily
The majority of patients reported no pain or
Most importantly, the mechanical effect allows for tissue routines. Measurable results are evident after a single treatment.
discomfort during or following treatment
selectivity - only adipose cells within the targeted area are The option of additional treatments is available to individuals
Normal blood and urine profiles confirmed
disrupted while surrounding tissues including blood vessels, seeking enhanced results*.
physiologically manageable fat clearance
Histological and clinical evidence of selective nerves, and connective tissue remain unharmed.
damage to adipose tissue
An embedded ultrasound imaging system concurrently
No serious adverse effects
provides real-time feedback regarding acoustic contact. Contour I - Making a measurable
difference to more patients' lives
Fat Clearance Process
Advanced Tracking and Guidance Software Designed by plastic surgeons with physicians
Selective fat cell lysis takes place without causing damage to in mind, the UltraShape treatment is easily
neighboring blood vessels and nerves. Triglycerides from the The UltraShape treatment is guided by a real-time tracking and guidance system designed to guarantee administered by physicians or other healthcare
disrupted adipocyte cells are released into the interstitial fluid homogenous body contouring results. The system includes a software algorithm that maps the three professionals. Intended for the office
and gradually transported through the vascular system to the dimensional treatment zone. Precision and safety are reinforced by an optical image guidance device environment, it eliminates operating room
liver. The liver makes no distinction between fat originating which prevents treatment beyond the pre-marked zone and precludes repeat treatment. and anesthesia expenses. The system provides
from the disrupted adipocytes and fat derived from a consumed a user friendly, time-saving and cost effective
meal. The cell debris is removed through the physiological The tracking system addresses the dynamic nature of the treated area, a major challenge in body treatment platform that safely delivers a
pathways. contouring. As the patient breathes and moves, the fat being non-rigid, undergoes spatial deformities. measurable reduction in body circumference.
To overcome these obstacles, the system records and synchronizes the body's position in real-time, Patients who previously avoided invasive
enabling the patient to move freely or even get up during treatment. When the patient returns, the treatments will welcome this new body
system accurately resumes treatment. contouring option.

Ultrasound imaging transducer

Focused ultrasound therapeutic


Figure 1: Histopathological sample immediately
transducer
following the UltraShape treatment (Hematoxylin-
Eosin staining, x50). Image shows disrupted adipose
Low energy everywhere except
tissue with no damage to adjacent blood vessels. in the focal area

Figure 2: Histopathological sample immediately


following the UltraShape treatment (Hematoxylin-Eosin
staining, x25). Image shows damage only to fat cells * Still under clinical evaluation. Please refer to the
while skin and connective tissue remain unharmed. UltraShape website for the latest clinical updates.
Combining Safety with Effectiveness Revolutionary Technology Convenience for You and Your Patients
The only solution to combine non-invasive treatment with measurable results The Contour I system is based on two proprietary technological innovations: A safe and simple “walk-in, walk-out” office-based

Safe clearance of lysed adipose tissue via the body's natural mechanisms Non-invasive focused ultrasound treatment
A non-invasive option when surgery is not desired
An average reduction of two centimeters in body circumference after a single treatment Tracking and guidance software
Treatment areas include abdomen, flanks and thighs
No downtime, no recuperation period and no maintenance
treatments
Clinical Results Non-Invasive Focused Ultrasound Minimal training with short learning curve
The safety and effectiveness of Contour I is backed by The UltraShape technology is based on focused therapeutic
Contour I - The practical patient-friendly alternative
scientifically demonstrated results from multi-center clinical ultrasound which selectively lyses adipocytes. A predetermined
trials performed on hundreds of patients worldwide. amount of ultrasound energy is applied to the subcutaneous The UltraShape treatment is the first non-invasive body
Results include: fat layer where acoustic waves converge in a confined focal contouring solution to lyse fat cells safely and effectively in
volume causing mechanical disruption of fat cell membranes. both men and women. The treatment takes an average of
An average reduction of two centimeters in body
Since energy is delivered in pulses, there is no significant one and a half hours and is carried out in an office environment.
circumference following a single treatment
temperature elevation. Afterward, patients can immediately resume their daily routines.
The majority of patients reported no pain or
Most importantly, the mechanical effect allows for tissue Measurable results are evident after a single treatment. The
discomfort during or following treatment
selectivity - only adipose cells within the targeted area are option of additional treatments is available to individuals
Normal blood and urine profiles confirmed
disrupted while surrounding tissues including blood vessels, seeking enhanced results*.
physiologically manageable fat clearance
Histological and clinical evidence of selective nerves, and connective tissue remain unharmed.
damage to adipose tissue
An embedded ultrasound imaging system concurrently
No serious adverse effects
provides real-time feedback regarding acoustic contact. Contour I - Making a measurable
difference to more patients' lives
Fat Clearance Process
Advanced Tracking and Guidance Software Designed by plastic surgeons with physicians
Selective fat cell lysis takes place without causing damage to in mind, the UltraShape treatment is easily
neighboring blood vessels and nerves. Triglycerides from the The UltraShape treatment is guided by a real-time tracking and guidance system designed to guarantee administered by physicians or other healthcare
disrupted adipocyte cells are released into the interstitial fluid homogenous body contouring results. The system includes a software algorithm that maps the three professionals. Intended for the office
and gradually transported through the vascular system to the dimensional treatment zone. Precision and safety are reinforced by an optical image guidance device environment, it eliminates operating room
liver. The liver makes no distinction between fat originating which prevents treatment beyond the pre-marked zone and precludes repeat treatment. and anesthesia expenses. The system provides
from the disrupted adipocytes and fat derived from a consumed a user friendly, time-saving and cost effective
meal. The cell debris is removed through the physiological The tracking system addresses the dynamic nature of the treated area, a major challenge in body treatment platform that safely delivers a
pathways. contouring. As the patient breathes and moves, the fat being non-rigid, undergoes spatial deformities. measurable reduction in body circumference.
To overcome these obstacles, the system records and synchronizes the body's position in real-time, Patients who previously avoided invasive
enabling the patient to move freely or even get up during treatment. When the patient returns, the treatments will welcome this new body
system accurately resumes treatment. contouring option.

Ultrasound imaging transducer

Focused ultrasound therapeutic


Figure 1: Histopathological sample immediately
transducer
following the UltraShape treatment (Hematoxylin-
Eosin staining, x50). Image shows disrupted adipose
Low energy everywhere except
tissue with no damage to adjacent blood vessels. in the focal area

Figure 2: Histopathological sample immediately


following the UltraShape treatment (Hematoxylin-Eosin
staining, x25). Image shows damage only to fat cells * Still under clinical evaluation. Please refer to the
while skin and connective tissue remain unharmed. UltraShape website for the latest clinical updates.
Highlights Company Profile
The first body contouring solution to combine safety with effectiveness UltraShape, founded in 2000, develops, manufactures and markets innovative, non-invasive
An average reduction of two centimeters in body circumference after a single treatment solutions for the aesthetic medical field. The UltraShape expert team of scientists is dedicated to the
Lysed adipose tissue cleared via the body's natural mechanisms development of cutting edge body contouring technology that enhances patients' self image and
Tracking and guidance system ensures homogeneous treatment sense of well being.

Non-invasive, focused ultrasound technology First to market - UltraShape offers a unique technology that positions the company as the pioneer
Long-term reduction of fat cell population through mechanical effects in non-invasive body contouring. The revolutionary UltraShape Contour I is the first computer guided
Selective emulsification of adipose tissue, leaving neighboring tissues unharmed non-invasive body contouring system to emulsify fat cells selectively using focused ultrasound
technology.
A measurable difference to more patients' lives
UltraShape Inc. was established in Delaware by Ami Glicksman M.D., formerly a senior plastic surgeon
“Walk-in, walk-out” office based treatment
at the Sheba Medical Center, Tel Aviv, and Yoram Eshel, Ph.D, MBA, a leading expert in medical
An effective option when surgery is not desired
physics with fifteen years experience in high power ultrasound technology. UltraShape Ltd. operates
No disruption to patients’ daily routine
through its fully owned subsidiary in Israel.
No downtime and no need for maintenance treatment
The company adheres to the highest scientific and quality standards. UltraShape is ISO 13485: 2003 certified.

DBR-10004 Rev. C
Before treatment After two treatments System Components
Transducer:
Delivers the focused ultrasonic beam
Provides real-time feedback on acoustic contact
System Console:
Comprised of the ultrasound generator, power unit, cooling system and system computer
Courtesy of: C. Inglefield, M.D., BSc, London, UK Stand:
Illumination system and tracking system based on a single video camera
System display screen and control panel

Before treatment After a single treatment

Specifications
Technology Focused ultrasound
Key Standards IEC 60601-1, IEC 60601-1-2, IEC 60601-1-4, UL60601-1, CSA 22.2
Certifications CE Mark, CSA, CB Scheme
Acoustic output ISPTA= 17.5 W/cm2
Ultrasound operation frequency 200± 30KHz
Courtesy of: P. Heden, M.D., Stockholm, Sweden Input voltage 100, 115, 200, 230V, 50-60 Hz, factory set
Dimensions Where Safety and Effectiveness Finally Meet
Cabinet (HxLxW) 0.65 x 1.15 x 0.55 meters
Light Stand (Height) 2.2 meters
Before treatment After a single treatment Weight
Cabinet & light stand 150 kg
Transducer 1.85 kg

List of Patents:
This product and its use are protected by one or more of
the following patents and/or pending patent applications:
US 6607498; US 20030083536 A1; US 20040106867 A1;
WO 02/054018; WO 04/00011
* Contour I is not yet available in the US
© 2006 UltraShape Ltd. All rights reserved.

Courtesy of: J. Burns, M.D., Dallas, TX, USA 30 Habarzel St., Tel Aviv 69710 Israel, Tel:+972-3-6457100 Fax:+972-3-6479321
0344 Toll free number: +800-22557252 info@ultrashape.com www.ultrashape.com
Highlights Company Profile
The first body contouring solution to combine safety with effectiveness UltraShape, founded in 2000, develops, manufactures and markets innovative, non-invasive
An average reduction of two centimeters in body circumference after a single treatment solutions for the aesthetic medical field. The UltraShape expert team of scientists is dedicated to the
Lysed adipose tissue cleared via the body's natural mechanisms development of cutting edge body contouring technology that enhances patients' self image and
Tracking and guidance system ensures homogeneous treatment sense of well being.

Non-invasive, focused ultrasound technology First to market - UltraShape offers a unique technology that positions the company as the pioneer
Long-term reduction of fat cell population through mechanical effects in non-invasive body contouring. The revolutionary UltraShape Contour I is the first computer guided
Selective emulsification of adipose tissue, leaving neighboring tissues unharmed non-invasive body contouring system to emulsify fat cells selectively using focused ultrasound
technology.
A measurable difference to more patients' lives
UltraShape Inc. was established in Delaware by Ami Glicksman M.D., formerly a senior plastic surgeon
“Walk-in, walk-out” office based treatment
at the Sheba Medical Center, Tel Aviv, and Yoram Eshel, Ph.D, MBA, a leading expert in medical
An effective option when surgery is not desired
physics with fifteen years experience in high power ultrasound technology. UltraShape Ltd. operates
No disruption to patients’ daily routine
through its fully owned subsidiary in Israel.
No downtime and no need for maintenance treatment
The company adheres to the highest scientific and quality standards. UltraShape is ISO 13485: 2003 certified.

DBR-10004 Rev. C
Before treatment After two treatments System Components
Transducer:
Delivers the focused ultrasonic beam
Provides real-time feedback on acoustic contact
System Console:
Comprised of the ultrasound generator, power unit, cooling system and system computer
Courtesy of: C. Inglefield, M.D., BSc, London, UK Stand:
Illumination system and tracking system based on a single video camera
System display screen and control panel

Before treatment After a single treatment

Specifications
Technology Focused ultrasound
Key Standards IEC 60601-1, IEC 60601-1-2, IEC 60601-1-4, UL60601-1, CSA 22.2
Certifications CE Mark, CSA, CB Scheme
Acoustic output ISPTA= 17.5 W/cm2
Ultrasound operation frequency 200± 30KHz
Courtesy of: P. Heden, M.D., Stockholm, Sweden Input voltage 100, 115, 200, 230V, 50-60 Hz, factory set
Dimensions Where Safety and Effectiveness Finally Meet
Cabinet (HxLxW) 0.65 x 1.15 x 0.55 meters
Light Stand (Height) 2.2 meters
Before treatment After a single treatment Weight
Cabinet & light stand 150 kg
Transducer 1.85 kg

List of Patents:
This product and its use are protected by one or more of
the following patents and/or pending patent applications:
US 6607498; US 20030083536 A1; US 20040106867 A1;
WO 02/054018; WO 04/00011
* Contour I is not yet available in the US
© 2006 UltraShape Ltd. All rights reserved.

Courtesy of: J. Burns, M.D., Dallas, TX, USA 30 Habarzel St., Tel Aviv 69710 Israel, Tel:+972-3-6457100 Fax:+972-3-6479321
0344 Toll free number: +800-22557252 info@ultrashape.com www.ultrashape.com

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