Mock Board Exam 2019

Mock Board Exam Module 5

Pharmaceutical Dosage Form, Physical Pharmacy, Manufacturing Pharmacy & Pharmaceutical Jurisprudence
and Ethics

Name: _________________________________________________Date: _______________ Score: ______

Shade your answer on the examination answer sheet provided. STRICTLY NO ERASURES.

1. Used in tablet and capsule formulations to improve flow properties of the powder mixture.
a.Tablet lubricant b. Tablet glidant c. Tablet disintegrant d. Tablet opaquant
2. Used in tablet formulations to reduce friction during tablet compression.
a. Tablet lubricant b. Tablet glidant c. Tablet disintegrant d. Tablet opaquant
3. Which of the following given is consider as example of a tonicity agent?
a. Sodium chloride b. Mineral oil c. Sodium glycolate d. Liquid glucose
4. It describes the passage of (drug) molecule through a membrane that does not actively participate in the process.
a. Drug absorption b. Transport mechanism c. Passive diffusion d. Osmosis
5. The rate and extent to which an active drug ingredient or therapeutic moiety is absorbed from a drug product and
becomes available at the site of action.
a. Drug’s solubility b. Adsorption c. Peak concentration d. Bioavailability
6. Drug products that contain the identical therapeutic moiety or its precursor but not necessarily in the same amount
or dosage form as the same salt or ester.
a. Pharmaceutical alternatives c. Pharmaceutical equivalents
b. Bioequivalence drug product d. Therapeutic equivalent
7. Drug products that contain identical amounts of the identical active drug ingredients, that is, the same salt or ester
of the same therapeutic moiety, in identical dosage forms but not necessarily containing the same inactive
ingredients.
a. Pharmaceutical alternatives c. Pharmaceutical equivalents
b. Bioequivalent drug product d. Therapeutic equivalents
8. Drug substance physiochemical properties that influence bioavailability of oral drugs.
a. Particle size b. Liquid solubility c. Salt form d. All of the above
9. Pharmaceutical ingredients that influence bioavailability of oral drugs.
a. Fillers b. Lubricants c. Binders d. All of the above
10. Characteristics of dosage forms that influence the bioavailability of oral drugs.
a. Disintegration rate b. Storage condition c. Dissolution rate d. All of the above
11. Physiologic factors that influence the bioavailability of oral drugs.
a. Gastric emptying time c. Pathologic condition
b. Intestinal transit time d. All of the above
12. Site of sublingual route of administration
a. Rectal b. Under the tongue c. Heart d. Spine
13. A coronary vasodilator used in the prophylaxis and treatment of angina pectoris, which dissolve under the
tongue.
a. Aspirin b. Phenytoin c. Aspilet d. Nitroglycerin
14. Which statement is not true for rectal route of administration?
a. Used for local effect c. Used for systemic effect
d. 100% of drug absorbed bypass the liver d. Inconvenient
15. Semisolid that has greater aesthetic appeal for their non-greasy character, ability to vanish into the skin upon
rubbing and ability to absorb serous discharges from the skin lesions.
a. Pastes b. Powder c. Lotions d. Creams
16. Semisolid that contain more solid materials, stiffer and less penetrating, preferred when protective action is
desired.
a. Ointment b. Suspension c. Pastes d. Lotion
17. Dosage form of choice if increased spreadability over large areas of skin is desired.
a. Cream b. Pastes c. Ointment d. Lotion
18. Characteristics of ophthalmic preparations, EXCEPT
a. Sterile c. Usually absorbed in great extent
b. Free of grit d. None of the above
19. Site of excretion of volatile drugs
a. Kidney b. Saliva c. Sweat glands d. Lungs
20. Solid dosage forms in which medicinal agents and/or inert substances are enclosed in a small shell of gelatin.
a. Capsules b. Suppositories c. Tablets d. Coated tablet
21. It is obtained by the partial hydrolysis of collagen obtained from the skin, white connective tissue, and bones of
animals.
a. Agar b. Albumin c. Gelatin d. Dye
22. Temperatures that thermally bond the capsules’ cap and body.
a. 15°C-20°C b. 30°C-35°C c. 20°C-25°C d. 40°C-45°C
23. Preservative used for soft gelatin capsules
a. Glycerin b. 80% ethyl alcohol c. Sorbitol d. Methylparaben
24. Compressed tablets coated with a thin layer of a polymer capable of forming a skin like film.
a. Sugar coated b. Enteric coated c. Film coated d. Buccal tablet
25. Tablet which has a smooth rapid disintegration when chewed or allowed to dissolved in the mouth has a creamy
base, usually of specially flavored and colored mannitol.
a. Sugar coated tablet b. Buccal tablet c. Chewable tablet d. Sublingual tablet
26. The shaft portion of the needle is called the:
a. Bevel b. Cannula c. Lumen d. Hub
27. Alcoholic and hydroalcoholic solutions prepared from vegetable materials or from chemical substances,
prepared usually by maceration and percolation.
a. Extracts b. Tinctures c. Fluidextracts d. Elixirs
28. Concentrated (1g/mL) alcoholic or hydroalcoholic solutions representing the therapeutically active principles of
vegetable drugs prepared by percolation process:
a. Extracts b. Fluidextracts c. Tinctures d. Elixirs
29. Clear, pleasantly flavored, sweetened hydroalcoholic liquids intended for oral use as flavors and vehicles for
substances:
a. Elixirs b. Tinctures c Fluidextract d. Extracts
30. A homogenous mixture in which the molecules of the solute are dispersed among hose of the solvent:
a. Suspensions b Emulsions c. Solutions d. All of the above
31. A two-phase system prepared by combining 2 immiscible liquids, one of which is uniformly dispersed
throughout the other:
a. Suspension b. Solution c. Emulsion d. Magma
32. Preparations containing finely divided drug particles uniformly distributed throughout a vehicle in which the
drug exhibits a minimum degree of solubility:
a. Emulsion b. Suspension c. Solution d. None of the above
33. Lugol’s solution is:
a. Strong iodine solution c. Povidone-iodine solution
b. Potassium iodine oral solution d. None of the above
34. The following solvents are used in the preparation of oral solutions, syrups and elixirs except:
a. Alcohol, USP b. Purified water, USP c. Propylene glycol d. Ethylene glycol
35. An example of an anionic emulsifying agent is:
a. Benzalkonium chloride c. Polyethylene glycol
b. Sodium lauryl sulfate d. Magnesium trisilicate
36. The following substances produce which emulsions, except:
a. Gelatin b. Egg yolk c. Cholesterol d. Casein
37. Bougies is another term for:
a. Vaginal suppositories c. Urethral suppositories
b. Rectal suppositories d. None of the above
38. Anhydrous lanolin is a /an:
a. Hydrocarbon ointment base c. Absorption ointment base
b. Water-removable ointment base d. Water-soluble ointment base
39. The following are hydrocarbon ointment base except:
a. Petrolatum b. Hydrophilic petrolatum c. White petrolatum d. Mineral oil
40. Part of the usual aerosol valve assembly that holds the gasket in place and is the mechanism by which the
actuator retracts when pressure is released, returning the valve to the closed position.
a. Stem b. Mounting cup c. Gasket c. Spring
41. Part of the usual aerosol valve assembly that is attached to the aerosol can or container and holds the valve in
place.
a. Actuator b. Mounting cup c. Stem d. Spring
42. Part of the usual aerosol valve assembly which extends from the housing down into the product and brings the
formulation from the container to the valve.
a. Stem b. Spring c. Dip tube d. Actuator
43. Part of the usual aerosol valve assembly which are made of plastic EXCEPT
a. Actuator b. Housing c. Stem d. Mounting cup
44. Temperature necessary to liquefy the propellant gas in aerosol
a. 0°C and below b -10°C to -15°C c. -34.5°C to -40°C d. -15°C to -20°C
45. Sterile, pyrogen limited preparations intended to be administered parentally
a. Aerosols b. Injections c. Ophthalmic solution d. All of the above
46. Small amount of powder may be blended by the movement of a pharmaceutical spatula thru the powders on a
sheet of paper or pill tile
a. Spatulation b. Tumbling c. Trituration d. Sifting
47. Very fine powders intended for the different body cavity such as ears, nose, throats, teeth and vagina.
a. Douche powder b. Dusting powder c. Insufflations d. Teas
48. Study of particles
a. Micromeritics b. Micromerics c. Micrometics d. Micromintics
49. A thin semi-opaque paper having limited moisture resistant qualities.
a. Simple white bond paper b. Vegetable parchment c. Glassine d. Waxed
50. Tablets that are prepared by compressing granular effervescent salts or other materials having the capacity to
release gas (CO2) when in contact with water.
a. Effervescent tablet c. Layered tablets
b. Press coated tablet d. Enteric coated tablets
51. The dissolution of a drug is calculated using:
a. Henderson-Hasselbalch b. Arrhenius c. Noyes-Whitney d. Stokes
52. The number of moles of solute per liter of solution:
a. normality b. molality c. molarity d. none of the above
53. Crystalline form of NaCl:
a. tetragonal b. hexagonal c. cubic d. monoclinic
54. An equation which reveals the rate of diffusion of a drug:
a. Noyes-Whitney c. Nernst Film Theory
b. Fick’s First Law d. Fick’s Second Law
55. The attractive forces between polar molecules, that is, between molecules that possess dipole movement:
a. Keesom Forces c. Dispersion Forces
b. Van der Waals Forces d. Ion-Dipole Forces
56. The attractive interaction between a polar molecule and the induces dipole;
a. Ion-Induced Dipole Interaction c. Induced Dipole
b. Dipole-Induced Dipole Interaction d. Ion-Dipole Forces
57. When the stressed is removed, a ____ system returns to its original state of fluidity.
a. Plastic b. Dilatant c. Pseudoplastic d. Newtonian
58. An example of liquid-liquid interface.
a. Emulsion b. Suspension c. Mixture d. Gels
59. The ratio of the void volume to the bulk volume of the packing
a. porosity b. packing arrangement c. bulkiness d. flow properties
60. Kinematic viscosity is also known as:
a. relative viscosity b. absolute viscosity c. fluidity d. stress
61. The following are not organic molecular complexes, except;
a. Clathtrates b. Picric acid type c. Channel Lattice Type d. Olefin Type
62. The ff are hydrophilic substituents, except:
a. alkyl groups b. amino group c. hydroxyl group d. carbonyl group
63. Proposed Law of heat summation
a. Boyle’s Law b. Hess Law c. Charles’ Law d. Gay Lussac’s Law
64. The fastest order of reaction to decompose, since according to its differential rate expression, it is independent
of the remaining concentration of the drug after decomposition:
a. zero b. pseudo-first c. first d. second
65. The increase in mutual solubility of 2 partially miscible solvent by another agent is referred to as:
a. salvation b.salting out c. miscellar solubilization d. blending
66. One of these exhibit dilatant flow:
a. cream b. ointment c. paint d. acacia mucilage
67. Ascorbic acid is the least stable of all vitamins. Its instability is via this reaction:
a. photolysis b. hydrolysis c. none of the choices d. oxidation
68. If 1 gram of solute dissolves in 30-100 parts of solvent, the solute is said to be _________ in that solvent:
a. freely soluble b. soluble c. sparingly soluble d. slightly soluble
69. Equation showing the buffer capacity of a solution
a. Raoult’s Law c. Van Slyke Equation
b. Stoke’s Law equation d. Vant Hoff’s equation
70. Using White-Vincent Method, compute for the required volume to make 0.3 g of Atropine sulfate (E=0.13)
isotonic.
a. 4.3 ml b. 3.9 ml c. 25.6 ml d. 33.3 ml
71. Which of the following is not a derived dimension?
a. Volume b. Density c. Velosity d. Length
72. The critical pressure of water is ____.
a. 200 atm. b. 260 atm. c. 218 atm. d. 180 atm.
73. It is an example of solids which exists in tetragonal form.
a. Sodium chloride b. Iodoform c. Sucrose d. Urea
74. It is an example of solid which exists in rhombic form.
a. Iodine b. Sodium chloride c. Iodoform d. Boric acid
75. The following are example of amorphous solids except.
a. Glass b. Woods c. Plastics d. Minerals
76. It is the phenomenon where compounds exists in more than one crystalline and/or amorphous form.
a. Polymorph b. Polymorphic form c. Modification d. Polymorphism
77. Different polymorphic forms of a substance usually exhibit different.
a. X-ray diffraction patterns c. Stability activity
b. Dissolution behavior d. All of the above
78. It is the process of the transformation of solids directly into the vapor phase without passing into the intermediate
liquid phase.
a. Evaporation b. Condensation c. Distillation d. Sublimation
79. It is the heat which results in the change of matter without increasing the temperature.
a. Latent heat c. Heat of vaporization
b. Heat of fusion d. Heat of sublimation
80. As the temperature is raised, the density of the vapor increases while that of liquid ______.
a. Increase b. Decrease c. Maintained d. Critical
81. It is the temperature at which the vapor pressure of a liquid equals the external or atmospheric pressure.
a. Boiling point c. Freezing point
b. Melting point d. Latent heat of vaporization
82. It is the temperature at which a solid pass into liquid state under atmospheric pressure.
a. Latent heat b. Freezing point c. Melting point d. Boiling point
83. It is the diameter of a spherical powder particle having the same surface area as that of the asymmetric particle in
question.
a. Surface diameter b. Volume diameter c. Projected diameter d. Stroke’s diameter
84. A data set in which there is a considerable closeness among the values
a. Accurate b. Approximate c. Estimate d. Precise
85. A type of Van der Waals forces of attraction which involves permanent dipoles inducing polarity in non-polar
molecules.
a. Debye b. London c. Keesom d. H-bond
86. This law relates the volume and pressure of given mass of gas at constant temperature
a. Boyles b. Charles c. Gay-Lussac d. Ideal Gas Law
87. This law gives the relationship between the total pressure in a mixture of gases and the partial pressure of the
individual gases
a. Ideal Gas Law b. Raoult’s Law c. Graham’s Law d. Dalton’s Law
88. This is the heat absorbed by 1 mole of liquid when it passes into the vapour state
a. Molar Heat of Fusion c. Boiling point
b. Molar Heat of Vaporization d. Entropy
89. The temperature at which the vapour pressure of the liquid equals the external or atmospheric
a. Melting point b. Boiling point c. Freezing point d. Sublimation
90. Crystals showing different characteristics in various directions along the crystal are
a. Monotropic b. Isotropic c. Anisotropic d. Enantiotropic
91. This is are types of liquid crystals which are also known as the soap-like or grease-like crystals
a. Smectic b. Nematic c. Cholesteric d. Thermotropic
92. This was the first recorded type of liquid crystals that was derived through the application of heat
a. Cholesteryl benzoate b. Calcium sterate c. Sodium benzoate d. Potassium acetate
93. This is the property of crystals which the mesophase also possess characterized as the ability to let light pass
through and divide into two components with different velocities and refractive index
a. Refraction b. Polymorphism c. Birefringence d. Isomerism
94. The resistance of the liquid to flow is termed as;
a. Bulkiness b. Fluidity c. Liquidity d. Viscosity
95. The physical property of liquid which is directly proportional to temperature is;
a. Boiling point b. Heat of vaporization c. Surface tension d. Vapor pressure
96. Which of the following crystals is held together by covalent bonds?
a. Sodium chloride b. HCl c. Graphite d. Kl
97. The geometric pattern exhibited by iodine is;
a. Cubic b. Hexagonal c. Triclinic d. Rhombic
98. The condition wherein substances can exist in more than one crystalline form is known as;
a. Anisotropicity b. Polymorphism c. Fusion d. Sublimation
99. Which property of the mesophase is associated with the crystalline state?
a. Flow property b. High property c. Permeability d. Birefringence
100.The type of liquid crystal used in developing display system is;
a. Cholesterol b. Nematic c. Pneumatic d. Isotropic