NATIONAL UNIVERSITY OF SCIENCE AND TECHNOLOGY

DEPARTMENT OF APPLIED CHEMISTRY

ANALYTICAL CHEMISTRY 1: SCH1206

Lecturer: Dr. A. Maringa, Office SD68

Office Hours/Consultation: All free slots in my work schedule from Monday to Friday
between 0800hrs and 1600hrs.

COURSE AIM:
This course introduces students to analytical chemistry and the fundamental principles that
make up analytical chemistry.

EVALUATION:
Final grades for the Course will be based on one 3-hour exams at the end of the semester.
Final Exam: (EX) 60%
Continuous Assessment (CA) 20%
Practical assessment (PA) 20%

DETAILED COURSE OUTLINE

1. Introduction to Analytical Chemistry

1.1 Aims of chemical analysis and role of the analyst.
1.2 Steps in the analytical investigation.

2. Statistical Treatment of Data

2.1 Precision, Accuracy, confidence limits.
2.2 Errors in chemical analysis.

3. Chemical Equilibrium
3.1 Stepwise and overall equilibrium constants.
3.2 Conditional equilibrium constants.
3.3 Le Chartelier’s principle

4. Acid-base Equilibria
4.1 Bronsted-Lowry theory, strong and weak acids and bases.
4.2 Buffer solutions involving monoprotic and polyprotic systems.
4.3 Titration curves, acid-base indicators.
4.4 Titration in non-aqueous solvents.
4.5 Application of acid-base titrations.

5. Complex-formation Equilibria
5.1 Complex-formation processes. Stability constants.
5.2 Titrations with inorganic complexing reagents.
5.3 Titrations with aminopolycarboxylic acids.
5.4 Metallochromic indicators.
5.5 Application of acid-base tritrations.

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6. Redox Equilibria
6.1 Redox processes and redox equilibrium constants.
6.2 Titrations with inorganic complexing reagents.
6.3 Oxidation and reducing agents in redox titrations.
6.4 Application of redox titrations.

7. Precipitation Equilibria
7.1 Precipitation processes. Solubility and solubility product. Differential
precipitation.
7.2 Effect of common ion, pH and complex ion formation on solubility.
7.3 Precipitation titrations. Indicators.
7.4 Gravimetric analysis.

Selected References
1. Skoog, D.A., West, D.M. and Holler, F.J., (1996), Fundamentals of Analytical Chemistry
(7th edition), Saunders College Publishing.
2. Skoog, D.A., Holler, F.J. and Nieman, T.A., (1998) Principles of Instrumental Analysis (5th
Edition), Saunders.
3. Harris, D.C., 1998, Quantitative Chemical Analysis, Freeman
4. F. W. Fifield and D. Kealey, Principle and Practice of Analytical Chemistry, 5th
Edition