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Reference: G. Kaur, H‐C. Cheung, W. Xu, J.V. Wong, F.F. Chan, Y. Li, L. McReynolds, L. Huang
“Milligram scale production of potent recombinant small interfering RNAs in Escherichia coli”,
Biotechnology and Bioengineering. 2018;1–12.
Innovations help to select the best strain in shortest time!
Selection of best clones that are producing your product of interest is a time-consuming process,
especially if the optimization and selection performed in a fermenter. Cleaning, preparation, setting up a
fermenter for Autoclave before a Run is a difficult job with traditional fermenters. But
these problems are eliminated in the MINIFOR Fermenter and Bioreactor system by introducing
many revolutionary changes.
MINIFOR is advantageous to work with aerobic and micro-aerophilic or anaerobic bacterial (e.g.: E.
coli, B. subtilis, B. anthracis, B. amyloliquefaciens, B. pumilus, B. licheniformis, S. aureus, etc.) and yeast
(e.g.: S. cerevisiae, P. pastoris, S. pastorianus, S. uvarum, etc.) cultures (co-culture) under batch, fed-
batch or continuous (chemostat) mode of operation.
Parameter control: temperature, agitation, pO2 (OD), pH, air flow rate by internal thermal MASSFLOW
gas flow control (controlled supply of air for aerobic or N2 for anaerobic process)