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Thank you for having selected our system and welcome to the ever growing world club of users for Milestone
laboratory instrumentation.
We are sure that you will be completely satisfied with this new tool entering your laboratory.
We invite you to read caCODEully this operator manual and to keep it in reach for convenient and fast
consulting.
For any possible clarification or any request for assistance please contact either our Representative in your
country:
Or contact
Milestone s.r.l.
Via Fatebenefratelli, 1/5
24010 Sorisole (BG) Italy
Tel. +39.035.412 8264
Fax +39.035.575498
web site www.milestonemedsrl.com
e-mail marketing@milestonemedsrl.com
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MacroPATH pro-x MM113-002 – Operator Manual
SUMMARY
SUMMARY ........................................................................................................................................................ 4
1. INTRODUCTION ........................................................................................................................................ 6
1.1. Symbols used .................................................................................................................................... 6
1.2. Introduction to MacroPATH pro-x ...................................................................................................... 6
1.3. Technical Specifications .................................................................................................................... 7
1.4. Transport and storage conditions ...................................................................................................... 7
1.5. Warning explanation .......................................................................................................................... 8
1.6. Antivirus ............................................................................................................................................. 8
1.7. Backup MacroPATH pro-x data (IMAGES CASES) .......................................................................... 9
1.8. Milestone Remote Connection........................................................................................................... 9
1.9. Marking plates for MacroPATH pro-x ................................................................................................ 9
2. INSTALLATION ........................................................................................................................................ 10
2.1. Unpacking check list MacroPATH pro-x .......................................................................................... 10
2.2. PC panel connections overview ...................................................................................................... 11
2.3. MacroPATH pro-x installation .......................................................................................................... 12
2.3.1. Camera connections ................................................................................................................ 12
2.3.2. Panel connections ................................................................................................................... 13
2.3.3. Camera Lens Setup ................................................................................................................. 14
2.3.4. Camera orientation .................................................................................................................. 15
3. OPERATING MacroPATH pro-x .............................................................................................................. 16
3.1. Start the MacroPATH....................................................................................................................... 16
3.2. Log in and Log out ........................................................................................................................... 17
3.3. How to operate ................................................................................................................................ 17
3.3.1. Create a case........................................................................................................................... 17
3.3.2. Enable led light ........................................................................................................................ 18
3.3.3. Edit a case ............................................................................................................................... 18
3.4. Overview of the functions ................................................................................................................ 19
3.4.1. Keyboard hot keys ................................................................................................................... 20
3.4.2. Multifunctional buttons ............................................................................................................. 21
3.4.3. Foot pedal ................................................................................................................................ 22
3.5. FILE functions .................................................................................................................................. 22
3.6. LIVE functions .................................................................................................................................. 26
3.6.1. Create/retrieve ......................................................................................................................... 27
3.6.2. Save Image/Video/Audio ......................................................................................................... 27
3.6.3. Thumbnails .............................................................................................................................. 29
3.6.4. Extra camera settings .............................................................................................................. 29
3.6.4.1 Camera Tab ............................................................................................................................. 30
3.6.4.2 AWB Tab (auto white balance) ................................................................................................ 30
3.6.4.3 Areas ........................................................................................................................................ 31
3.6.4.4 Camera firmware version ......................................................................................................... 32
3.7. EDIT functions ................................................................................................................................. 33
3.7.1. Tools ........................................................................................................................................ 33
3.7.2. Utility display ............................................................................................................................ 37
3.7.3. Utility functions ......................................................................................................................... 38
3.8. SETTINGS ....................................................................................................................................... 40
3.8.1. General settings ....................................................................................................................... 40
3.8.2. User settings ............................................................................................................................ 40
3.8.3. Licensing settings .................................................................................................................... 41
3.8.4. Storage settings ....................................................................................................................... 43
3.8.5. Camera settings ....................................................................................................................... 44
3.8.6. Calibration ................................................................................................................................ 45
3.8.7. Third party settings .................................................................................................................. 45
3.8.8. Localization settings ................................................................................................................ 47
3.8.9. Appearance settings ................................................................................................................ 48
3.8.10. Tools settings ........................................................................................................................... 49
3.8.11. PCODEerences settings .......................................................................................................... 51
4. MacroPATH pro-x AS A MULTISTATION VIEWER................................................................................. 53
4.1. How to install the MacroPATH pro-x as viewer ............................................................................... 53
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MacroPATH pro-x MM113-002 – Operator Manual
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MacroPATH pro-x MM113-002 – Operator Manual
1. INTRODUCTION
Biohazard: be caCODEul when you execute the procedure marked with this symbol:
danger of biohazard contamination.
Manufacturer.
MacroPATH pro-x has been designed to carry out complete, safe and reliable image handling of gross
histological samples.
The system has been conceived for laboratory use and can theCODEore withstand the harshest laboratory
conditions; equipment is intended for laboratory use (indoor use only).
Because the MacroPATH pro-x auto-sizing tool is strictly related to the calibration done
by the operator and is not controlled by the software of the unit, sample measurements
obtained with MacroPATH pro-x are NOT TO BE CONSIDERED AS DIAGNOSTIC values.
It is in fact necessary to position a ruler by the sample (see picture below) or to use a caliper to get a
diagnostic value of the tumor growth, lesion extension etc…
It is necessary to calibrate the system (see chapter 3.8.6 for calibration procedure) when making a
measurement with MacroPATH pro-x.
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MacroPATH pro-x MM113-002 – Operator Manual
- 4 ports inside the cover dedicated to the connection of: camera, foot pedal and keyboard (if present).
- 4 USB ports located on the lower portion of the PC, which can be used to connect the barcode reader, for
example.
Camera pro-x:
Camera resolution: up to 16Megapixel
Focus: Automatic
White balancing: Automatic
Zoom magnification: 10x optical (Provided with set of three lenses at different close-up)
Weight: 3.9kg +250g the power supply (8.6Ibs+0.55lbs)
Power Supply: Input rating: 100÷240V~ 50/60Hz, 0.7A
Including: Camera holder for photographic stand
Built-in LED
Dimensions: WxHxD 250 x 120 x 210mm (9.85” x 4.72” x 8.27”)
Software
Operating system: Windows 7 Ultimate ® 64bit
Microsoft Windows 7 and Microsoft Word are Microsoft Corporation registered brands
MacroPATH 5 software: Installed (complete with license)
The manufacturer reserves the right to change and/or improve specifications without notice and
without incurring in any obligation.
Environmental conditions:
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MacroPATH pro-x MM113-002 – Operator Manual
Use of the equipment in ways different than those specified may void the warranty provided by the
manufacturer.
The panel PC shall be connected only to 3-pole earthed main socket outlet (Protective earth must be
provided). This note is not valid for the camera power supply.
Main plugs are considered as disconnecting device. Disconnect both main plugs from the socket outlet
before assembly of the system, before connection of the accessories and before cleaning.
Equipment shall be connected to main sockets outlets which is accessible and visible by the operator.
Equipment is not provided with replaceable fuses. If the system is still not properly working, please contact
your local representative or the manufacturer (always provide the serial number of the unit, see label on the
back of the PC panel unit).
All parts of the equipment and all accessories shall be supplied only by the manufacturer.
In case of malfunction, please shutdown the PC Panel, then restart them again. If the system is still not
properly working, please contact local representative or the manufacturer.
It is very important to switch the PC OFF before disconnecting the MacroPATH pro-x
Camera and then disconnecting the camera USB/LAN connection and cable in order not to
damage the Camera interface board.
Besides the CDs of the MacroPATH pro-x software, Milestone will also provide for each
unit genuine Microsoft Windows 7 CDs. We strongly recommend that each user makes
sure that the original CDs provided with each unit are kept in a safe place, as Milestone is
not in a position to supply other CDs or copy of them.
The License serial number is on the backside of the PC Panel and reported in the QC
Report of the unit.
1.6. Antivirus
Milestone suggests to install an antivirus software. Milestone does not install antivirus software so that you
can choose your pCODEerred version, according to your needs.
Pay attention when setting the Antivirus so that data flow on the USB/LAN protocols and accesses to the
Hard Disk are not limited.
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MacroPATH pro-x MM113-002 – Operator Manual
Milestone strongly suggests storing all cases with relative images on a server with an
automated backup procedure.
Contact your local Network/IT Manager.
The dimension of the images with the suggested settings is around 1.2Mb/image (see Chapter 3.6.4).
The unit is provided with a DVD burner to be used for back up of the cases folder using the provided tools.
Do not run any burning program during the LIVE mode of MacroPATH pro-x application.
MacroPATH pro-x software is provided with Milestone Remote Connection that allows our Customer Support
to manage the unit remotely. To be able to obtain support from Milestone, connect the PC to Internet, then
contact customer support at customersupport@milestonemedsrl.com and communicate these data:
MILESTONE SRL
Via Fatebenefratelli, 1/5 – 24010 Sorisole (BG) – ITALY
Tel. +39.035.4128264 Fax. +39.035.575498
MACROPATH PRO-X
CODE 370410 SERIAL NUMBER (SN)
MANUFACTURED:
ID Model Rev.
For the explanations of the symbols, please CODEer to the chapter 1.1.
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MacroPATH pro-x MM113-002 – Operator Manual
2. INSTALLATION
Installation and preliminary operations are illustrated in this section. Please caCODEully read the following
chapters before operating the MacroPATH pro-x.
When unpacking, verify that all parts correspond your product order.
Description CODE
A) POINT-OF-CARE CONTROL TERMINAL (PC Panel) + Pointer Pen 370254/S
B) Camera Pro-x + Set of three lens 370449
C) Foot Pedal Control 370033
D) MacroPath pro-x proprietary software and License CODE
370262
E) Table stand microphone 370039
F) Sizing Ruler 40219
B
C
F
D
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MacroPATH pro-x MM113-002 – Operator Manual
A C
Description:
A. Power cable connection
B. PC-Panel power switch
C. LAN connections
USB Camera connection to the Panel PC
USB Foot pedal connection for remote control of Zoom-in/out and save (connect to the BROWN
marked)
USB available for keyboard and barcode reader
DVI-I VGA for external video connection
D USB ports
Microphone (“MIC-IN” connector) and audio line out (“SPEAKER OUT” connector) connections
MIC-IN
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MacroPATH pro-x MM113-002 – Operator Manual
The installation of MacroPATH pro-x is a simple process, only taking a few minutes. Make sure that the
power is not connected when installing the cables.
This is not a standard lan connection. Never connect to the net facility network.
The camera Pro-x is a “USB device” of the PC. For that if you have a USB device (for
example a USB key) connected to the PC and you want to disconnect it, pay attention to
do not disconnect the camera from the PC. If this happens, follow the procedure reported
in the chapter 7.1.
Insert the proper (115V or 230V) power supply cord in the connector of the camera’s power supplier.
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MacroPATH pro-x MM113-002 – Operator Manual
Connect the camera’s power supplier to the 12-24V DC camera connector, as shown in the picture below.
When all connections are done, the led shown in the photo below positioned on the back of the camera lights
up.
Connect the USB foot pedal to the USB port marked with BROWN.
Connect the keyboard USB connector (if present) to a USB port.
Connect the bar code reader USB connector (if present) to a USB port.
Connect microphone to the MIC-IN connector.
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MacroPATH pro-x MM113-002 – Operator Manual
By default the lens +1 is mounted on the camera; at the installation time it is possible to
change it if required, depending on the information reported in the table below.
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MacroPATH pro-x MM113-002 – Operator Manual
GUIDE FOR DETERMINING THE DISTANCE OF THE CAMERA PRO-X FROM THE SPECIMEN
AND TYPE OF LENS USED
We suggest installing the objective of the camera at about 65cm (25.6inch) from the
working surface using a +1 lens.
The automatic autofocus capability of the camera depends on environmental conditions. The values reported
above are experimental results obtained from Milestone tests captured at 100% of zoom level.
If you loose the two white knobs, the camera turns on the right or on the left; when you find the best
orientation, fix its position tight the 2 knobs.
On the back of the camera there is a support for photographic stands, as shown in the square below.
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MacroPATH pro-x MM113-002 – Operator Manual
Working with MacroPATH pro-x is a very easy and friendly operation. All functions are described in the
following paragraphs.
Start the MacroPATH pro-x PC Panel by pressing to “I” on the switch on the back.
Let Windows starts up and wait almost 30 seconds. Then double click on the MacroPATH Pro icon on the
desktop.
Pro1
It is required to wait almost 30seconds before starting the software; this is a time
necessary to the PC to see the camera.
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MacroPATH pro-x MM113-002 – Operator Manual
Acquire images, video and audio by using the icons at the left side of the screen or the foot pedal. (See 3.6.2
chapter).
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MacroPATH pro-x MM113-002 – Operator Manual
If you switch off the PC, the light will continue. If you want to switch off it, you need to press again the button.
Double click on a thumbnail or select EDIT icon on the right top of the screen to enter EDIT mode.
Edit the images using the tools in this area (see 3.7 chapter).
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MacroPATH pro-x MM113-002 – Operator Manual
MacroPATH pro-x functions are grouped in 4 areas: FILE, LIVE, EDIT and SETTINGS.
AREA FUNCTIONS
FILE Browse, delete, tag and present the existing cases
LIVE Save image, video and audio files
EDIT Modify acquired images
SETTINGS Modify settings of the FILE, LIVE and EDIT
The following screen is available only for MacroPATH pro-x complete software (but not for the Viewer).
E C
A B
D
G
F
L M
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MacroPATH pro-x MM113-002 – Operator Manual
Some functions can also be accessed by pressing on the keyboard (see table below):
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MacroPATH pro-x MM113-002 – Operator Manual
Multifunctional buttons:
Camera management
Measuring tool
Line tool
Text tool
Quadrant
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MacroPATH pro-x MM113-002 – Operator Manual
5
4
2
1 3
1 Zoom in control
2 Zoom out control
3 Save control: allows to acquire images (snapshot) and to save modified images
4 Back to live: allows to go back to LIVE
5 Audio rec: allows to record an audio file in LIVE and or in EDIT
A case can be retrieved by inserting either the name, creation/last edited date, creator/last editor or tag, and
then pressing “filter” button.
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MacroPATH pro-x MM113-002 – Operator Manual
Reset Search: press this icon to undo all previous modifications and see the case list.
Print case: press this icon for a complete or partial printout of the case. Select the template and
then the picture to print.
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MacroPATH pro-x MM113-002 – Operator Manual
Present case: press this icon and the whole case (images, video and audio) is displayed
It is possible to tag a case also by the live screen. When a case is opened and you are in live screen, you
can add a tag of the current case by pressing the icon “Add tag”, as shown in the image below.
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MacroPATH pro-x MM113-002 – Operator Manual
Delete case: press this icon to delete a case. Double confirmation is requested to avoid errors.
Yes Yes
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MacroPATH pro-x MM113-002 – Operator Manual
In LIVE it is possible to create/retrieve a case, acquire images, take a video and modify extra camera
settings.
When the camera has not been used for about 6 hours, it turns off automatically to
preserve its life, as explained below.
At this time, the procedure of “camera wake up” starts: the live screen is stopped and the following message
appears. The maximum time is 90 seconds, during this period do not press any button, just wait.
During the normal use of the camera, sometimes a fast buffering is automatically executed to extend its life.
In this case the following message appears, for a maximum of 20 seconds. During this time do not touch any
button.
In particular this procedure may be applied also when the camera is switched off by pressing its icon
and then switched on and when entering in edit mode. In these cases the message “Buffering” showed
above may appear for a few seconds, do not touch any button and wait.
To extend the life of the camera, by default under “Settings” screen (see the chapter 3.8.11), it is set a
standby of the camera after 1hour. So when Macropath will not be used for 1hour, the camera turns off and
the live screen becomes black. If you want to switch on the camera, press its icon, as shown below.
When the camera is switched on, the message “Buffering” showed above may appear for a few seconds.
If you want to unable the standy of the camera, please contact our service department at
customersupport@milestonemedsrl.com.
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MacroPATH pro-x MM113-002 – Operator Manual
3.6.1. Create/retrieve
Enter case identifier by barcode reader or manually with keyboard to create or retrieve a patient file. When
Save an image of the specimen by zooming in/out with the foot pedal control until the desired
area of interest is viewed, then press Snapshot button on CPU screen or Save on foot pedal.
When you press “Save”, if the image is not taken (“Image not taken”), please retry again.
Import an image from a TWAIN camera (for example a microscope camera): press the “TWAIN”
icon and select the TWAIN source
Use the TWAIN camera software to acquire the image (the software is provided by the twain camera
supplier).
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MacroPATH pro-x MM113-002 – Operator Manual
Check that microphone audio switch is ON before using it. See below.
Take video by pressing Rec Video button. Press again to stop recording
Before taking a video for the first time, when you press the icon “Rec video” you will be required to choose
the correct video Codec.
Milestone suggests to use “Microsoft video 1” compression.
Go to settings screen to change compression type in the settings screen (see chapter 3.8.11).
Press Rec Audio button to record. Press again to stop the recording.
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MacroPATH pro-x MM113-002 – Operator Manual
3.6.3. Thumbnails
Saved images, videos and audio appear on the right of the screen (Thumbnails).
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MacroPATH pro-x MM113-002 – Operator Manual
Skip focus before snapshot: enable this option to maintain the showed focus. It allows a faster image
acquisition.
Snapshot quality: allows to set the acquisition quality. Follow also the 3.8.4 chapter settings to decide the
best compression quality for images.
To set the image quality taken it is required to set properly two parameters as follows:
1. Compression Quality: the amount of compression applied to the image file (see chapter 3.8.4).
2. Snapshot quality: the dimension of the image.
From these two parameters depends the size of the image file.
The table below lists all possible combinations.
Milestone suggests setting cameras to get Snapshot quality “16 Mpx” and Compression Quality “Standard”
(see chapter 3.8.4). As this is a good compromise between file size (disk consumption space) and quality of
the image to report.
Should images be used for publications (articles, papers etc), Milestone suggests to choose quality “16 Mpx”
and “Full” Data compression.
Note that the space required for each image is the double that which is reported on the
table above. In fact, the system automatically saves each image in both JPEG and m5p
formats.
The changes will be saved in the configuration in use (see chapter 3.8.5).
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MacroPATH pro-x MM113-002 – Operator Manual
By default “Auto” is selected and it is suitable when you are not aware of the type of light source of the
grossing room.
These modifications take place when the user press “yes” to the message that asks to confirm the saving of
the modifications, and it is not necessary to restart the software.
If several cams are present, start each one and modify settings for each cam.
The changes will be saved in the configuration in use (see chapter 3.8.1).
3.6.4.3 Areas
Select “Areas” as shown below.
By default, the camera applies a focus in the center of the screen; it is done automatically and it is suggested
to use it. Anyway if you want to resize the focus area applied into the center, you can check “Enable Focus
area” showed above. If enabled, the Focus area will use the values showed under “Focus area” that are:
“500” as width and “400” as height. It is possible to modify these fields, if required.
If you want also to visualize the focus area into the live screen, select also “Show Focus Area” (a green
square will show the focus area before to get the snapshot).
As explained above, the Area Focus is automatically centered in the middle of the screen. However it is
possible to click on any point of the live window: the area will be automatically re-centered on the selected
point and it will be resized to fit to the values indicated under “Area Focus Click”, showed in figure above. For
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MacroPATH pro-x MM113-002 – Operator Manual
example below the green Area Focus is shown and it is centered on the lower right part of the screen, after a
click in that zone.
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MacroPATH pro-x MM113-002 – Operator Manual
Single click on the desired picture, video or audio, or click on the EDIT button to enter the Annotation mode.
In the Annotation mode, it is possible to add text, measurements, graphic elements and sections to the
picture, examine the tissue, record audio or directly print out.
Select: click the “SELECT” button to use the mouse as a pointer, or to select every item to be
modified. Once selected the graph annotating draw (follows as “item”) it is possible to move the
item, or to modify the color line of the item, color background of the item, color text and text size
of the item with the Multifunction Keypad.
Section letter
Section number
Text and line color
Background color
Line thickness
Text size
Annotation rotation
Labels enable/disable
3.7.1. Tools
Sizing
Click and keep the “Sizing” icon pressed with the mouse or the touch pen. The toolbar circled in
red appears.
Click on “Sizing line” icon to draw linear measurement; the system calculates the length of the line.
Click on “Sizing area” icon to draw an area on the specimen; the system calculates the area taken.
Click on “Sizing free” icon to draw freehand lines; the system calculates the length of the line.
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MacroPATH pro-x MM113-002 – Operator Manual
Software needs to be calibrated when unit is installed and every time camera height changes.
See chapter 3.8.6 for calibration procedures. Because MacroPATH pro-x auto-sizing tool is
strictly related to the calibration done by the operator and is not controlled by the
software of the unit, sample measurements obtained with MacroPATH pro-x are NOT TO
BE CONSIDERED AS DIAGNOSTIC values.
It is in fact necessary to position a ruler by the sample (see picture below) to use a caliper to get a
diagnostic value of the tumor growth, lesion extension etc…
Draw Lines
Click onto the Lines icon with the mouse or the touch pen. Point and drag the desired line on the
picture.
Keep holding the button to activate the multiple choice of Lines, Circles, Squares, Arrows,
Compass, and freehand drawing tool.
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MacroPATH pro-x MM113-002 – Operator Manual
Add Texts
The addition of text can be made by selecting the “AbcText” icon, then pointing and dragging
until the desired text box appears: release and enter desired text by the keyboard or bar code.
PRESET CUSTOM TEXT: (see also chapter 3.8.8 to see how add preset texts)
Once the list has been customized, click on the “AbcText” icon and keep it pressed until the list is displayed:
chose the text required to enter it.
Add Sections
Click onto the Section icon with the mouse or the touch pen. Point and drag the desired line on
the picture
Keep holding the button thus activating the multiple choice of labeling styles (either A, 1, A-1 or 1-A).
Modify the sequence of the letters and numbers by clicking with the pointer on the section line and then the
relatives button on the multifunctional keypad. See the arrow to adjust the sequence of letters and numbers
(see Multifunction keypad description in this chapter).
Add multisections
Click onto the Multi Section icon to display the available tool options (4 or 6 quadrants). Choose
a point on the screen and drag the desired sections onto the picture.
By press the section button line with the SELECT function, it is possible to deactivate labels and rotate
sections. See Edit functions (3.7) “Select” tool.
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MacroPATH pro-x MM113-002 – Operator Manual
Click and hold the Cassette Footprint icon to display the available tool options (Standard
cassette or Super Mega cassette). Choose a point on the screen and drag the desired sections
on the picture.
Rotate the Cassettes Footprint using the Multifunction Keypad on the lower left corner of the work area. See
Edit functions (3.7) “Select” tool.
Zoom region
Click onto the ZOOM icon with the mouse or the touch pen. Point and drag the desired zoom
region on the picture: the software automatically creates a new cropped image
Keep holding the button thus activating the multiple choice of section styles (zoom in, zoom out and zoom
fit).
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MacroPATH pro-x MM113-002 – Operator Manual
Grid
Click onto the GRID icon with the mouse or the touch pen to add a grid. In SETTINGS screen it
is possible to modify color, thickness and spacing of lines. Camera calibration will have to take
place prior to use of the Grid tool. See section 3.8.6.
User can easily view case assets in the library by using the following controls.
1. Scroll arrows (up/down) at the top and bottom of the library allow for movement through the case.
2. Images/Audio/Video tabs at the top of the library allow for the filtering of individual file types.
(Example: having only the Images tab highlighted causes only the still captured images to be
displayed in the library)
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MacroPATH pro-x MM113-002 – Operator Manual
Remove the last edit on the image: press the Undo button and the last entry on the
screen disappears (cancellation is done from the last to the first edit). Press Redo
button to restore a removed edit.
Undo/Redo functions are not operational in case of images with edits already saved.
Delete
The Delete function allows for the removal of case assets in multiple ways. A deleted image
cannot retrieved later.
1. Choose an image, audio or video thumbnail from the Library and press the Delete
icon.
2. Selecting and holding down the Delete icon will display and window containing all
case assets. You will be able to select multiple files for removal.
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MacroPATH pro-x MM113-002 – Operator Manual
Rec Audio
Save image
When all necessary edits have been made, click or touch on Save icon, as indicated, to save
them. Images can also be saved by foot pedal by pressing the Save command.
If Exit to Live icon is pressed and edits have not been saved, the system warns if you wish to
save them
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MacroPATH pro-x MM113-002 – Operator Manual
3.8. SETTINGS
Access and modification of settings is possible according to users access level (see chapter 3.8.2).
Press SAVE and it restart the software to enable the changes
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MacroPATH pro-x MM113-002 – Operator Manual
It’s possible to set default settings collected under green tabs, as “Localization”, “Appearance”, “Tool” and
“PCODEerences”, for all existing users by clicking “Set for all existing users” under the paragraph 3.8.1
“General”.
DO NOT PERFORM THE PROCEDURE WITHOUT THE SUPPORT NEITHER CHANGE ANY
DATA.
Click on Licensing button to manage the licensing file or to verify your licensing status.
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MacroPATH pro-x MM113-002 – Operator Manual
To obtain (in case after a problem, you wish to receive a new license file):
• Insert the Product Key printed on the MacroPATH CD (see the arrow in the previous picture)
• Press “Regenerate” (indicated by the circle in the figure above),
• Press “Copy to Clipboard” button, to copy the Machine ID (indicated by the circle in the figure above),
• Paste in a text file or directly in the e-mail message,
• Describe the reason why it is necessary to have a new license,
• Send email to customersupport@milestonemedsrl.com,
• On receipt the reply mail save the file you received from Milestone customer support,
• Press “Import file” (indicated by the circle in left figure below) and select the .lic5 file saved,
• Press “Save” button of “settings” screen (indicated by the arrow below).
• Restart MACROPATH and verify in “Settings” that the license level is “Unlimited”, as shown below.
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MacroPATH pro-x MM113-002 – Operator Manual
In order to perform an adequate and proper installation, in particular in case of multistation (more than one
MacroPATH unit installed), it is strongly required that the units store the data on to a share folder stored on a
server. To correctly perform the installation, as the software allows to store the data to more than one path,
the 1st path has to be the shared folder present on the server. The shared folder has to be set with FULL
CONTROL for each account and for each PC running the MacroPATH software.
So the 2nd path should be the local folder (present on the internal hard disk drive of the PC-panel), then we
can suggest the path, for Microsoft Windows 7:
C:\Users\Public\Documents\Milestone srl\MacroPath5\IMAGES
As shown in the image below (that shows an example for the 1st path):
\\SERVER\Pathological Anatomy\Laboratory\MacroPath\IMAGES
In the local folder will storage ONLY the cases created and opened by the local MacroPATH that you are
using. The shared folder on the server will collect ALL the cases created and managed by all the
stations/units.
Data compression: it is possible to set three different compression qualities: “Full Quality”, “Standard” and
“Low file size”. CODEer to chapter 3.6.4.1 to set the best compression according with the snapshot quality.
High definition: if selected, a filter is applied on the image to have more constrast. By default it is not
checked. When used, more seconds are required to make a picture.
This function is not needed for camera pro-x (developed for previus models of camera).
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Enabled shared folder management: The shared folder management is useful when more MacroPATH
stations are working on the same cases. In fact, with this function activated, when a case is opened by a
station and another MacroPATH tries to open it, a warning message appears, communicating that the case
is already opened by another system and displaying its IP address and when the case has been opened.
Below an example.
Before using this function, please contact our Service Department at:
customersupport@milestonemedsrl.com.
Select “Cam1” or more such as “Cam2”, “Cam3”, “Cam4” and “Cam5” depending
of number of cameras present.
Click on Camera short name field to modify the name of the camera.
Select:
• Trust external calibration: MacroPATH pro-x keeps the calibration factor from previous case
• Force calibration so that MacroPATH pro-x requires to calibrate every image (useful if camera is
moved before capturing the image).
• Auto measure function not available.
• Vertical Flip Image: vertical mirroring.
• Horizontal Flip: horizontal mirroring
• Priority: in case of two or more cameras connected to MacroPATH pro-x, choose the selection
sequence.
Zoom mode: choose either Extended mode (default and recommended: 100% optical zoom) or standard
mode (reduced optical zoom for optimal focus in special cases).
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MacroPATH pro-x MM113-002 – Operator Manual
Foot Pedal: enable foot pedal (if connected) by choosing the serial number in the list shown.
Calibration Procedure: by pressing this button it is possible to calibrate the Unit, as explained in the
following chapter.
3.8.6. Calibration
Click the “Calibration Procedure” button and position the ruler on the work surface. Press Focus if the
image is not well focused and press Go.
Insert the distance (in mm) between the two edges of the image (see picture)
Repeat the operation for different zoom levels (7 times). At the end press Save.
The calibration procedure is required whenever the position of the camera or the type of
the lens are changed.
Each camera has its calibration, then each camera must be calibrated independently of
each other.
Select the “External application” checkbox, as show below. In the image is reported an example to recall
“Notepad”. To do that it is required to fill the fields under External application1:
- “Application”: it is the address, in this case “C:\Windows\System32\notepad.exe”
- “Process”: it is the name of the application, in this case “Notepad”
- “Image”: it represents the image of the icon that will be visualized to open the application, it is required to
browse an image “.CODEg”,
- Label: in this case “Notepad”.
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MacroPATH pro-x MM113-002 – Operator Manual
By clicking Shutdown MacroPATH after launch, at the starting of the external application, MacroPATH pro-
x closes down.
By clicking Disable MacroPATH after launch option, at the starting of the external application, MacroPATH
pro-x is disabled.
When “Disable MacroPATH after launch” box is selected, a dedicated program (not
included, to be provided by the customer/final user) must also be installed to enable user
to return to MacroPATH. On the contrary, return to MacroPATH is not possible and user
will have to restart the application MacroPATH trough the red cross “CLOSE” of windows
system.
DO NOT thick if not sure.
Customization of the Exit button is also possible: add label name and icon path.
Use MacroPATH pro-x camera and software as TWAIN devices of an external software (not included) is also
possible: enable Install virtual driver and choose:
Mode Description
To remove the case data and close the MacroPATH after importing the
Volatile Shutdown
images
To remove the case data and maintain active (reduced to icon) the
Volatile Minimize
MacroPATH after importing the images
To maintain the case data in the “TWAIN” folder and close the MacroPATH
Permanent Shutdown
after importing the images
To maintain the case data in the “TWAIN” folder and maintain active (reduced
Permanent Minimize
to icon) the MacroPATH after importing the images
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MacroPATH pro-x MM113-002 – Operator Manual
Tick Enable Twain acquisition to import images from an external imaging acquisition device (such as a
microscope, not included). On the main screen a new icon “From Twain” appears.
Preset custom text allows insertion of up to 100 different preset texts: press “Add” (see the circle in left
figure below) and type the category name (example “1”), then press the second “Add” (see the circle in the
right image below) icon and type the text (example “text1”)
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MacroPATH pro-x MM113-002 – Operator Manual
Tick Fullscreen checkbox to disable the preset titlebar and fill with your laboratory name.
Tick Virtual Keyboard to enable the keyboard icon. Clicking the icon, the virtual keyboard appears.
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Thick Fine Tune Mode: it is possible to modify icons, font and thumbs size.
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MacroPATH pro-x MM113-002 – Operator Manual
Set here your favorite configuration for each tool like font, color etc. and have them as default for each case.
Check the field to change the line drawing system (for size line and section line:
suggested for touch screen routine operation)
It is also possible to change font, color and thickness of text and lines in Edit screen (see picture below), but
these changes are valid just for the current case.
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A. AutoLive. Check the box to return to Live Mode when an image has been acquired and saved.
B. Auto Edit Mode. Check to automatically enter in Edit after image acquisition
C. Shutdown camera entering Edit mode. Check to shutdown camera during Edit operations. This
feature increases camera lifetime. By default it is checked, please do not modify it.
D. Force double entry. By checking this box, every time you create a case, you will be required two
times to enter the case name, thus avoiding misspelling and/or errors.
IT IS NOT POSSIBLE TO CHANGE THE CASE NUMBER AFTER ITS CREATION.
E. Live at start. Enable this check to go directly to LIVE when the software starts.
H. Cam standby after. Set the time (in seconds) after which the camera turns in standby mode. This
feature increases the camera lifetime. By default it is 1h, as explained in the chapter 3.6.
I. Delay for image during Present. Set delay time between each image in a presentation.
K. Reset recording video options. Press this button to cancel video settings. First time a video is taken,
user will need to set quality (see 3.6.2 chapter).
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MacroPATH pro-x MM113-002 – Operator Manual
Watermark settings can be modified in PCODEerences tab: select None, Simple or Bordered.
Bordered mode allows the insertions of information in the watermark. Uncheck data is not required.
In Simple mode a watermark is positioned over the image, while in bordered mode is put
below it.
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MacroPATH pro-x as viewer allows simple retrieval of MacroPATH pro-x images, using either barcode or
manual entry of patient identifying number. Images can only be viewed and printed (generating report as
explained in the previous chapter), but no modifications i.e. annotations are possible.
To carry out any modification on images (such as add notes, section and so on), an extra
license of MacroPATH pro-x software must be available. For this, contact your local
distributor.
MacroPATH pro-x as viewer is the same software installed on the MacroPATH pro-x unit
and it does not need a license. TheCODEore, user is authorized to install MacroPATH pro-
x as Viewer software on any PC.
MacroPATH pro-x Viewer can be installed on any computer: using the MacroPATH pro-x CD and open the
MacroPATH pro-x folder. Click on Set Up installer and follow the instructions to proceed with the installation
of the MacroPATH pro-x software.
Milestone strongly suggests that the following procedures are carried out by your local
Network/IT Manager.
Before proceeding with the instructions below, it is necessary to connect the MacroPATH
pro-x PC and the MacroPATH pro-x as viewer PC to a local network, setting it with
appropriate parameters.
It is now possible to work from both (or more) working stations. When a new case is added from histological
laboratory, every additional station is able to view and print the same images.
Milestone strongly suggests storing the cases on a server with an automated backup
procedure. Contact your local Network/IT Manager.
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MacroPATH pro-x MM113-002 – Operator Manual
The images created with Macropath pro-x are 100% compatible (open system). Images are stored in .JPG
formats which is universal formats. Any commercial software, pathology reporting, LIMS that are image
capable are suitable to retrieve and view images collected by Macropath Pro-x.
The system also produces a session file in each specimen directory detailing the Patient file ID, opening and
closing time for the specimen gross file.
The MacroPATH system can also receive the ID number directly by the LIMS system.
With Windows 7 all the specimens directory created by the user by typing the specimens codes are saved
(as default) in the directory path
C:\Users\Public\Documents\Milestone srl\MacroPath5\IMAGES
While Windows XP the images are saved (as default) in the folder path
C:\Documents and settings\All Users\ Documents\Milestone srl\MacroPath5\IMAGES.
As default this directory is created into the hard-disk C:, but the folder Images can be set on any different
location on the local network.
The example below shows the way as 5 images taken under the case ABC are saved into the directory
C:\Users\Public\Documents\Milestone srl\MacroPath5\IMAGES
All the images are saved in .JPG format. The MacropathD/PRO-Xsoftware automatically saves the images
with the ID name:
ABC_0001.JPG
ABC _0002.JPG
ABC _0003.JPG
ABC _0004.JPG
ABC _0005.JPG
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MacroPATH pro-x MM113-002 – Operator Manual
For every specimen case the software generates also an XML file with the information on the saved session.
All the images are then available to be retrieved and visualized by any other software.
With this command the LIMS can open the selected case directly in the MacroPATH pro-x software
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MacroPATH pro-x MM113-002 – Operator Manual
5. MAINTENANCE
DISCONNECT THE PLUGS FROM THE SOCKET BEFORE STARTING THE CLEANING
PROCEDURE.
During normal use the PC Panel and camera may become soiled and should, theCODEore, be cleaned
regularly.
Agents: Green tinctured soap and Enzymatic detergents.
Steps:
1. Prepare agent as per the manufacturer’s instructions or hospital protocol,
2. Wipe the PC Panel with a clean cloth that has been moistened in the cleaning solution,
3. Wipe thoroughly a clean cloth.
Do not immerse or rinse the PC Panel and its peripherals and the camera.
Do not use an abrasive cloth to clean the camera’s lens.
If you accidentally spill liquid on the device, disconnect the unit from the power source.
Contact your Biomed regarding the continued safety of the unit before placing it back in
operation.
Do not spray cleaning agent on the chassis.
Do not use disinfectants that contain phenol.
Do not autoclave or clean the PC Panel or its peripherals or the camera with strong
aromatic, chlorinated, ketone, ether, or Esther solvents, sharp tools or abrasives.
Never immerse electrical connectors in water or other liquids.
5.1.2. Keyboard
To clean while the keyboard is plugged in, lock the keyboard by pressing the Locking Key for three
seconds.
Clean the surface of the product by wiping, brushing, spraying or dipping it. Use only rags, sponges or soft
bristle brushes.
DO NOT place the USB connector into the fluid.
Either wipe with dry cloth or allow to air dry.
Unlock the keyboard by pressing the Locking key for three seconds.
Disinfectants recommended:
• Chlorine based (max 10% solution) – Chlorox, Novalsan, etc.
• Formaldehyde based - Formaldehyde Solution 37%, Vinco Formaldegen.
• Glutaraldehyde based – Aldacide 200, Lysofume, Wavicide, etc.
• Phenol based – Lysol I.C., Beaucoup, Magna Clean, Tek-Trol, etc.
• Alcohol based – Cavicide, Isopropyl Alcohol, Medicide, etc.
• Oxidizing – Hydrogen Peroxide 3% Solution, Lifegard Series, etc.
• Quaternary Ammonium – Roccal-D, Bacto-Sep, Parvosol, etc.
• Soap and water.
DO NOT USE: Petroleum based cleaning fluids, such as Gasoline, Acetone, over 10% bleach solutions,
temperature or pressure sterilization, buffing pads or scrubbing pads.
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MacroPATH pro-x MM113-002 – Operator Manual
6. ACCESSORIES (Optional)
Table top camera holder for MacroPATH pro-x camera. Heavy duty stainless steel cabinet. Includes also one
Macrostand WA (CODE 370285) showed in the chapter 6.7.
Only at the installation time you have to connect the base of the macrostand, as shown below. Use the 6
screws and the allen included.
Then you have to connect the camera pro-x to the table top camera holder, below it is shown the final
configuration.
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MacroPATH pro-x MM113-002 – Operator Manual
6.2. Pro-x Camera holder for hood type grossing station (CODE 370440)
In the following picture it is shown the clamp for mounting to the ceiling.
Below an example of the camera attached by the camera holder to a fumes hood.
In the following picture it is shown the bracket for mounting to the ceiling.
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MacroPATH pro-x MM113-002 – Operator Manual
This accessory allows to fix the camera to a pole with section between Ø30 and Ø50mm.
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MacroPATH pro-x MM113-002 – Operator Manual
Suited for mounting the touch screen terminal where space is restricted inside the grossing area, but with
sufficient floor space to mount the terminal on a mobile floor stand, that can be moved between grossing
stations, as required.
Description:
CODE 360073 Floor Type Terminal Holder on wheels (Schuko Socket)
CODE 360074 Floor Type Terminal Holder on wheels (US Socket)
CODE 360075 Floor Type Terminal Holder on wheels (Without Socket)
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MacroPATH pro-x MM113-002 – Operator Manual
Complete set-up for wet area photography i.e. over the dissection area.
including.
Bar code reader is usefull to automatically enter the patient/specimen number to open a new file or retrieve
an existing file.
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MacroPATH pro-x MM113-002 – Operator Manual
Bar code reader is usefull to automatically enter the patient/specimen number to open a new file or retrieve
an existing file. This model can read 2D barcodes also.
Water proof (sealed) keyboard with touch-pad built in, with IP68 protection against water and dust.
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MacroPATH pro-x MM113-002 – Operator Manual
If you get the following message “The camera is not responding” follow the procedure explained below.
• Press OK, then log out from the software.
• Switch off the PC.
• Then disconnect the camera’s power supplier, disconnecting the 12-24V DC camera connector shown
in the image below.
• Wait at least 5 seconds and then reconnect the 12-24V DC camera connector.
• Wait few seconds and restart the PC.
• Wait at least 30 seconds and then restart the software.
Open “Settings” from the relative icon and click the camera button. Select the serial number (each
foot pedal has its own serial number)
If two or more serial number are displayed, check if any external tool using the same drivers is connected.
Select a serial number, save and restart the software. If it still does not work, select the other serial number.
If any serial number is displayed:
1) Install the driver included in MacroPATH CD
2) Connect foot pedal control to another USB port.
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MacroPATH pro-x MM113-002 – Operator Manual
If touching the monitor with the pen the mouse arrow moves to another direction, recalibrate the
touch-screen as follows:
Select “TouchKit” icon from the “Windows” icon or from the “Start” menu, go to “Programs”, then
“TouchKit” and select “Configure Utility”.
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MacroPATH pro-x MM113-002 – Operator Manual
Press OK to close the window. Choose the “Tools” folder (see the circle below).
Now the green target appears: touch on its center with the pen pointer. Repeat for all the green targets that
are displayed.
At the end, a message appears to advise that the calibration is completed, press “OK” to continue.
The recalibration is now completed.
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MacroPATH pro-x MM113-002 – Operator Manual
This instrument is an in-vitro medical device and it is usually installed in a laboratory where specimens and
other biological tissues are present. For your safety, it is theCODEore required to clean and disinfect before
entering in contact with it.
Also you must wear gloves when operating with the system.
It is required in case of return that the unit is cleaned and disinfected before sending it back to
MILESTONE S.R.L. Non-disinfected devices will be no longer accepted and you will be contacted to get the
relative disinfection cost.
International health rules require that shipments of biohazard materials are not don in standard packages
(risk of sanctions).
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MacroPATH pro-x MM113-002 – Operator Manual
1) Switch the panel PC OFF. Disconnect the main plugs of the panel PC from the main socket outlets
2) Disconnect the main plug of the camera power supply from the main socket outlet.
3) Disconnect all accessories (foot pedal, keyboard, bar-code reader, camera, camera power supply).
4) Clean and disinfect all parts of the equipment according to the manufacturer specification.
5) Dispose all electric and electronic parts of the equipment according to the manufacturer:
Complying with directive 2002/96/EC of the European Parliament and of the Council of 27 January 2003 on
waste electrical and electronic equipment (WEEE), the separate collection environmental managed of
equipment is mandatory.
It is necessary to return the used equipment to the distributor or to inquire about the presence of a local
empowered system for collection and disposal of WEEE.
The in-observance of Directive 2002/96/EC or of the local law which acknowledge it can have potential
effects on the environment and human health
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Milestone Srl
marketing@milestonemedsrl.com
Via Fatebenefratelli, 1/5 - 24010 Sorisole (BG) - Italy www.milestonemed.com
Tel +39 035 4128264 - Fax +39 035 575498