COLLEGE OF PHARMACY AND CHEMISTRY

University of the Immaculate Conception Page 1 of 5

Father Selga St., Davao City
Title: PURPLE Review – Quality Control 1 and 2 Pretest Date: 25 APRIL 2019
Encoded by: P.A. M. SABIDO, BSPharm Batch: 2018 - 2019

1) Total Quality Management is responsible for establishing the system to ensure product quality.
Quality Control is responsible for the test and measure of materials and product.

A. Only 1st statement is true.

B. Only 2nd statement is true.
C. Both statements are false.
D. Both statements are true.

2) The basket rack assembly is a component of which of the following instrument?

A. Vernier Caliper
B. Hardness tester
C. Dissolution apparatus
D. Disintegration apparatus
E. Friabilator

3) Content uniformity is to be performed for all tablets whose active ingredient is

A. < 50 mcg
B. > 50 mcg
C. < 50 mg
D. > 50 mg
E. < 50 g

4) What is the maximum satisfactory hardness value of a compressed tablet?

A. 2 kg
B. 3 kg
C. 4 kg
D. 10 kg
E. 4 – 10 kg

5) Which of the following is not a basic component of the instrument used in NMR studies?

A. Detector and recorder

B. Radiofrequency transmitter
C. Magnet
D. Prism or diffraction grating
E. Method of sweeping through spectrum

6) If the requirement for the pyrogen test was not met, a retest is required using additional ____ rabbits
and the total sum of individual increase should not be more than ____.

A. 3 ; 3 oC
B. 5 ; 37.94 oF
C. 3 ; 37.94 oF
D. 3 ; 39.52 oF
E. 5 ; 39.52 oF
 COLLEGE OF PHARMACY AND CHEMISTRY
University of the Immaculate Conception Page 2 of 5
Father Selga St., Davao City
Title: PURPLE Review – Quality Control 1 and 2 Pretest Date: 25 APRIL 2019
Encoded by: P.A. M. SABIDO, BSPharm Batch: 2018 - 2019

7) Mull technique in IR spectroscopy is:

A. Dissolving the solid in a suitable organic solvent

B. Dissolving the solid in liquid petrolatum
C. Dispersing the finely ground solid in organic solvent
D. Dispersing the finely ground solid in liquid petrolatum
E. Incorporating the solid in a pellet

8) Wavelength used in all polarimetric measurements

A. 859 nm
B. 598 µm
C. 598 nm
D. 589 nm
E. 589 µm

9) It is used as a reference in proton NMR and is assigned a chemical shift of zero.

A. Trimethoxsilane
B. Trimethylsilane
C. Tetramethoxsilane
D. Tetramethylsilane
E. None of the Above

10) Which of the following is/are true regarding the transfer or delivery pipets?

A. Filling pipets by mouth is sometimes recommended

B. Wipe off any liquid adhering to the outer surface of the pipet
C. Pipets should be filled above 1 mm above the mark
D. Two of the above
E. All of the above

11) Bismuth could be solely analyzed in the presence of other metals through masking specifically by
adjusting the pH level at

A. pH 13
B. pH 11
C. pH 7
D. pH 5
E. pH 2

12) Which of the following factors affect the yield of alkaloids in plants except

A. Age of plant
B. Soil and climate
C. Conditions when collected, dried, & stored
D. Menstruum used in the extraction of the alkaloid
E. None of the above
 COLLEGE OF PHARMACY AND CHEMISTRY
University of the Immaculate Conception Page 3 of 5
Father Selga St., Davao City
Title: PURPLE Review – Quality Control 1 and 2 Pretest Date: 25 APRIL 2019
Encoded by: P.A. M. SABIDO, BSPharm Batch: 2018 - 2019

13) What drug/drug class is assayed with spectrophotometry?

A. Phenylmercuric nitrate
B. Chlorobutanol
C. Barbiturates
D. Sulfonamides
E. Steroids

14) What animal test is used to assay the nutritional completeness of protein hydrolysate injection?**

A. Guinea pigs
B. Mice
C. Rabbits
D. Rats**
E. Dogs

15) Which masking agent masks the presence of Co, Ni, Cu, and Zn?

A. Ascorbic acid
B. Ammonium fluoride
C. Potassium cyanide
D. Thioglycols
E. Citrate

16) In complexometry, what is the color transition when hydroxynaphthol blue is used as indicator and
Calcium as its analyte?

A. Red to Blue
B. Blue to Red
C. Purplish-green to Rose Pink
D. Rose Pink to Purplish-green
E. Blue to Green

17) Which among the following is a tetradentate ligand used in complexometry?

A. Ethylenediaminetetraacetic acid
B. Ethylenediamine
C. Glycine
D. Nitrilotriacetic acid**
E. Two of the choices

18) What volumetric precipitation method uses cyanide as analyte and it is a direct titration of silver
nitrate?

A. Mohr method
B. Fajan’s method
C. Volhard method
D. Gay-Lussac method
E. Liebig method**
 COLLEGE OF PHARMACY AND CHEMISTRY
University of the Immaculate Conception Page 4 of 5
Father Selga St., Davao City
Title: PURPLE Review – Quality Control 1 and 2 Pretest Date: 25 APRIL 2019
Encoded by: P.A. M. SABIDO, BSPharm Batch: 2018 - 2019

19) Before distillation process of Kjeldahl method, what is added to liberate ammonia which is then
distilled into a solution of boric acid?

A. H2SO4
B. conc. H2SO4
C. excess H2SO4
D. NaOH**
E. KOH

20) Which among the following substances is/are assayed with residual alkalimetry?

A. ZnO
B. Sodium potassium tartrate
C. Methenamine
D. Ethyl acetate
E. A&B

21) Which among the following sulfonphthalein indicators is color blue in base solutions?

A. Thymolphthalein
B. Bromocresol green
C. Methyl Orange
D. Methylene Blue
E. None of these

22) What indicator is used to assay morphine?

A. Methyl red
B. Methyl orange
C. Phenolphthalein
D. A&B
E. All of these

23) Reagent/s used in the limit test of Lead**

A. Hydroxylamine
B. Ammonium citrate
C. Ammonium cyanide
D. Two of the choices
E. All of the choices

24) Not a function of Material Inspection Section is:

A. To maintain periodic examination on the quality of inventories throughout all phases of storage,
shipping, and distribution
B. To sample and examine all raw materials received
C. To validate existing and tentative procedures of testing
D. Two of the above
E. None of the above
 COLLEGE OF PHARMACY AND CHEMISTRY
University of the Immaculate Conception Page 5 of 5
Father Selga St., Davao City
Title: PURPLE Review – Quality Control 1 and 2 Pretest Date: 25 APRIL 2019
Encoded by: P.A. M. SABIDO, BSPharm Batch: 2018 - 2019

25) What is used to determine the position of the separated radioactive components following
chromatography?**

A. Iodine vapors
B. Charring
C. Painting the column
D. Spraying with colored solutions
E. Geiger-Muller counter

26) What is the minimum required temperature of the disintegration media?

A. 95 oF
B. 98.6 oF
C. 35 – 37 oC
D. 97.7 oC
E. 36.5 – 37.5 oC

27) What temperature and description of the electric furnace that refers to ignition to constant weight?

A. 110 - 120 oC; very dull red heat

B. 105 oC; very dull red heat
C. 675 oC; dull red heat
D. 800 oC; bright red heat
E. 600 oC; dull red heat

28) Which among the following oils is/are heavier than water?

A. Clove oil
B. Cinnamon oil
C. Orange oil
D. A&B
E. None of these

29) It is a semi-conservative detection method in thin layer chromatography that detects derivatizing
agents.

A. UV Light
B. Visible Light
C. Iodine vapor
D. Ninhydrin
E. Charring

30) What is the equivalent weight of potassium permanganate?

A. 2
B. 3
C. 4
D. 5
E. 7