i.e.

Doce Vitamin A Protocol [for

measles virus]
[The first portion of this page was
written by Dr. Jaquelyn McCandless.]
Message #1
Re the 400,000iu for two days (Mega A Rx
for measles): This is reposting of Vit A Rx
for those who missed it. I'm concerned
that someone is giving 500,000iu in the
CLO form because of the danger of Vit D
toxicity. Though current fears of that are
probably overestimated, I think it is
unwise to give that much until we learn a
lot more.
At the DAN!, (in PA) Dr. Sidney Baker
spoke of a study showing that 200,000 iu
of Vitamin A was not enough to
ameliorate the impact of measles
infection - the children needed 400,000 iu
for two days (800,000 iu total). As I have
said, if the rubeola IgA salivary titers are
elevated (per our study), IgG levels are
very elevated, the child has a history of
strong reaction to MMR and/or followed
by regression soon thereafter, and
certainly with brain antibodies indicating
autoimmune reaction, I believe there is
indication they may benefit from this
large dose, followed by 10,000 to 25,000
per day per age and size. Some parents
are reporting benefit from even smaller
doses, as I was originally suggesting
250,000 iu 1st day, then 200,000, then
150,000 etc. with maintenance at 10,000
to 25,000 (subtracting the up to 5000 in
CLO, with the rest in fish oil A or vit A
palmitate.)
What kind to use? Fish oil vit. A vs vit. A
palmitate? Dr. Pangborn has given me the
following information - "Per the Merck
Index, the palmitate form of all-trans or
retinol is the preponderant ester in fish
liver oils (cod, shark). But I do not like
synthetic vit A palmitate unless one has
to use pharmacologic doses such as Sid
(Baker) is describing. ------ Synthetic
palmitate can be a problem in allergically
sensitive individuals. ----- Natural fish oil
includes all-trans-retinol, -ci-retinol, and
probably some very similar molecules.
There's no guarantee that a synthetic
palmitate will have these. -----I'm wary of
synthetics, but again, for >200,000 iu
doses one may have to use what's
practical. (This is item 10150 ("Vitamin
A") in the Merck index.)
To be practical in solid or powder
supplements, one finds vit A acetate.
Some potency is lost in the acetate form,
about 15%.
Under 5000 iu, there's no reason to test
serum retinol levels. Actually, tests are
not reliable anyway. The most important
thing is to watch for symptoms of A
overdose: headache, nausea, dry scaly
skin, vertigo, blurred vision and erythema
or rash. Serum calcium will be elevated,
as hypervitaminosis A features
hypercalcemia."

Message #2
I am getting lots of personal e-mails on
this subject, so want to clarify. Vitamin A
is particularly "used up" when measles
virus is present, and it has been shown
that in the presence of active measles
virus, a 2-day mega-dosing of 400,000 iu
of Vitamin A will affect the measles virus,
maybe not to completely exterminate it
but to create an extremely mild short-
lived case in those who have already
contracted the disease. 200,000 iu for 2
days was not effective. Definitive studies
on all this are on the horizon. In a
preliminary study of rubeola secretory IgA
from saliva from volunteers from your
groups, Dr. Vojdani at Immunosciences
discovered 14 out of 32 kids had positive
scores, 5 of them at 5+. We are in the
process of a more definitive study
analyzing both IgG in serum as well as
secretory IgA in saliva to try and get a
correlation between the two.
My current recommendations based on
the evidence is that IF your child:
has high serum IgG rubeola antibodies
and/or high secretory IgA antibodies
(saliva),
the MBP or other neural antibodies are
elevated (indication of autoimmune
process),
there is a history of reaction to or
regression after the MMR vaccine,
and there is ongoing gut problems,
your child may have intestinal measles,
as many who have been scoped and
PCR'd do (even spinal fluid has been
found in a group of kids to have positive
vaccine strain measles). Without the
benefit of scoping and getting positive
biopsy reports on the gut, many parents
have given their kids high doses of
Vitamin A. The protocols change, but
currently is 400,000 IU for two days,
followed by 10,000 to 25,000 depending
upon the size and age of the child. Blood
tests are unfortunately not useful, but
clinical observation is very important. A
scruffy rash usually around the neck, is
one evidence of Vit A toxicity; headache
which kids may not be able to tell us
about, is another. Lethargy or excessive
hyperactivity or any unusual sign should
be considered a possible overdose of A.
The toxicity of this is highly overstated,
and though there is a history of a child
getting hydrocephalus after getting
100,000, I heard that the child became
normalized after being taken off the
Vitamin A. There has been one death
from Vit A toxicity in an adult male who
ate nothing but polar bear livers.
Otherwise, it is a much needed and quite
safe vitamin, but it does store in the liver,
so 400,000 iu should be probably a one-
shot treatment, or certainly not to be
repeated more than twice a year. PLEASE
NOTE: These are MY recommendations
and not others at this point, and there
have been NO peer-reviewed studies, so
please know there's a lot we don't know,
and we need as much input as possible.
Some parents are reporting miraculous
improvements with these doses of A, but
not all by any means. As far as testing,
please at least get the serum IgG tests
and if you can get your child to spit, the
salivary IgA. I'll let you know more as I
find out.
Jaquelyn
For more information written by Dr.
McCandless about vitamin A, click here.

[my thanks to Dr. McCandless for allowing

me to use this information on my site]

Additional signs of toxicity

In addition to those sign of toxicity
indicated by Dr. McCandless above, I
found the following list on another
message board
Symptoms of vitamin A toxicity:
Bulging fontanelles (infants)
Bone pain or swelling
Craniotabes (infants and children)
Skin and hair changes
hair loss
seborrhea
cracking at corners of the mouth
Irritability
Decreased appetite
Poor weight gain (infants and children)
Vomiting
Drowsiness
For my kids, toxicity symptoms have
included dry and itchy rash, headache,
upset stomach, and cracks in the corners
of the mouth. I have read a few accounts
of children alternating between lethargy
and hyperactivity.

[This section is my son's experience.

I am not a medical doctor. Following
this section is the experience of
another family.]
[NOTE: Viruses are not technically "alive",
so any reference I make to "viral die off"
or "killing virus" is not technically correct.
I have tried to use the term "eliminate the
virus". Many medical professionals prefer
to use the term "suppress the virus".]
Brief history: Son age 7-1/2, always has
had visual stim issues, sometimes better
than other times. Addressing food and
supplement requirements, and chelation,
made them tolerable but still there.
I gave TwinLabs Allergy A at a very high
dose, altho not as high as recommended
above, every day for about a month with
no change, still had visual stim issues,
never developed signs of toxicity.
I tried the high dose vitamin A protocol as
recommended by Dr. McCandless to kill
measles virus. I used TwinLabs Allergy A,
and followed the protocol as indicated
above, for two days, then reduced slowly
over the next few days. On the 6th day,
my son developed the toxicity rash. I
reduced more quickly over the next few
days, finally stopping for a few days to let
the rash go away. Then I started it again
when the rash was gone and his visuals
had returned.
After a few weeks, this maintenance dose
was not enough, he was developing his
visuals again.
AARRGGHH!!!!!!
[My after-the-fact comment: It appears
that what is reported about measles virus
sucking vitamin A is correct. Until I did
this protocol again, see below, no matter
how high I went with vitamin A dosing, it
would just be sucked right out of my son's
body. If lower dose, the effect was gone
in minutes. At higher doses, it took days.
But it was still just sucked right out of his
body.]
So I tried a "more aggressive approach".
His rash was gone, visuals back again
even at a relatively high daily
maintenance dose.
So this time I gave an even higher dose of
TwinLabs Allergy A, plus 10,000 IU CLO.
The toxicity rash appeared on the second
day. When the rash appeared, I gave him
olive leaf extract [an anti-viral]. The third
day, I reduced to the 25,000 IU [TwinLabs
plus CLO], plus olive leaf extract. About
an hour after this second dose of OLE, he
had a major runny bm, ran all down his
leg and all over his shoes. Nasty stuff.
No visual problems for several days, even
at the "lower maintenance dose". I
removed the OLE and then a few days
later the TwinLabs. Now I give him about
10,000 IU CLO per day and it seems to be
sufficient for him.
I sent email to Dr. McCandless "for her
information and research purposes" and
asked if she could give suggestions on
what I might try if the visuals came back
again. She gave me information for
certain tests, rx and OTC items, including
Lauricidin [because of the olive leaf
extract success].
I had also given #3 and #4 the OLE when
I was giving it to #2. When I removed it
from #2, I also removed it from #3 and
#4. #2 showed no problems with it
removed. #3 and #4 had not shown any
changes when I was giving it. However,
when I removed it, #3 and #4 both
exploded in major skin rashes, and #4
also had goo in her eye, which she had
not had since about round 50 of
chelation. So I started back the OLE for
them. #3 has had a lingering skin rash,
which was *almost* gone with chelation
and addressing various other food and
supplement issues, but was still lingering
in a small amount and was much more
pronounced when OLE was removed. Now
it is gone. #4 new skin rash is gone now
also, plus the goo is gone from her eye.
During this time, my #2 developed the
vitamin A toxicity rash at the 10,000 IU
per day dose, so I reduced to 5000 IU.
This worked for a few weeks, then the
rash appeared again. So I reduced to
2500 IU per day CLO. This is really
amusing to me, that my son who had
major visual stims for basically the first 7
years of his life, now has no stims and
can only tolerate 2500 IU per day! In
addition to the rash, my son will also be
slightly hyper and begin his visual stims
when he has too much vitamin A. Very
strange.
The Lauricidin arrived on January 3. I had
been experimenting with the OLE, and
the rashes come and go depending on
how much OLE I give to #3 and #4. I will
drop the OLE for now and try the
Lauricidin for the rash issue.
#2 now has the vitamin A toxicity rash,
slight hyper, and return of visual stims
with 2500 IU of CLO. Very very very very
strange. I will now try the 1250 IU CLO.
Update
My kids had problems with the Lauricidin,
so I dropped it and began olive leaf
extract again. This removed all the
negatives of the Lauricidin, and the
positives of anti-viral are increasing. After
about a month, I was able to add the
Lauricidin again, altho viral die off now
causes yeast. For specifics on this
experience, click here.
I had to entirely drop the vitamin A for my
#2 son for about a month, then the
visuals returned and so I added it back.
After much experimenting with the dose, I
determined that 1,000 IU per day is okay.
Less than that, or more than that, and the
visuals return.
My son's benefits from this protocol:
No more visual stims! Increased
language, especially in spontaneity of use
of words rather than gestures. Loss of
residual echolalic speech. Increased
social interaction and pretend play. My
#4 received a dollhouse from Grandpa for
Christmas. When we set it up here, #2
went right over to it and did NOT line up
the people figures like he would have
done a few years ago. He sat the people
at the tables and said "man eat" [he is
still at phrases only, for the most part], he
put them in the beds and said "man
sleep". He had so much fun that #4 had
trouble getting him to let HER play with it.
So I went out and bought another one,
this one is a hotel. #2 put the people in
the pool and said "water, slide, weeeeee".
He puts them in the elevator and says
"man go up, go down", they "see TV",
they "sit on couch". They "sit on chair, eat
on table". They even call out to each
other "hey man, come here, sit on couch,
see TV".
My *non-medical* observations:
My son needed a higher dose than that
recommended above, plus the addition of
olive leaf extract. I would not recommend
giving the high dose for more than two
days. After two days, reduce down to a
maintenance dose. If the visuals return,
your child *might* need this protocol
again, or he might need OTHER anti-viral
[like olive leaf extract]. Or your child
might need a higher or LOWER
maintenance dose. Or your child might
need something else entirely [for
example, yeast will cause my son's
visuals to return, and for my son, viral
die-off caused yeast].
During the high dose protocol, watch for
signs of toxicity. These might be the rash,
as my son experienced. But your child's
signs might be different, for example
lethargy, nausea, headache, or any of the
symptoms listed above in Dr. McCandless'
information. If you notice any of those
symptoms, stop the high dose protocol.
Another family's experience
My daughter was 5-1/2 when we did the
high dose vitamin A. She had regressed
at 20 months, two weeks to the day after
her second MMR shot. She lost motor
skills previously acquired and began
looking from the sides of her eyes. She
had symptoms of poor fat digestion and
other GI issues. I had held off doing the
high dose vitamin A because of an active
seizure disorder. She was not on any
medication.
She had taken 10,000 iu of vitamin A
every day for approximately 8 months
when she was 4 years old. I stopped it
briefly and then increased it to 20,000 iu
for about 3 months. She appeared to
have less stomach troubles and a more
even mood with the vitamin A. I had
stopped giving vitamin A prior to the high
dosing. In part because I was trying to
solve her anxiety issues and in part
because I was readying to do the high
dose.
Her health was stable in spite of the
anxiety so I started her on 1000 mcg of
sublingual methyl B12. She had a hyper
reaction to it, I experimented but gave up
by the fifth day. She had a white stool
that day which is the sign of gut crisis of
unknown quantity, so I stopped the B12
experiment.
I tried to bring her back to her previous
stability but her health declined and the
anxiety became extreme. Dana posted on
the enzymes list that Olive Leaf Extract
worked for anxiety so I implemented it,
working up to 500 mg three times a day.
This eliminated anxiety but I had
increasing difficulty controlling yeast.
I ran out of OLE, she had been on 500
mg, 3 times a day dose for approx 6
weeks. 2-1/2 weeks ago later she spiked
a high fever that ran for 2 days. Then
developed white spots with red rings in
her mouth. She ran a low grade fever,
swollen tonsils and pink inside her ears.
Her mood was all over the place. I noticed
an increase in seizures which is normal
during illness. I believe this was
subclinical measles, measles without
rash.
On the fourth day from the start of fever,
I gave her 25,000 iu of vitamin A from
halibut liver. This caused a significant
improvement in mood. Seizure activity
normalized but that may be because her
health was improving any way, not a
direct result of the vitamin A. The next
day I gave her 50,000 iu of vit A and her
mood stabilized. The 6th day I gave none
and her mood stability disintegrated.
I gave 400,000 iu of vit A on day 7. Her
mood stabilized and her eye contact
became perfect, she has retained eye
contact since. I gave 400,000 iu of vit A
on day 8 and she had mild irritability. She
has no anxiety and she is no longer
taking OLE. She is still having seizures.
6 months later the benefits have not worn
off yet and she can take 5,000 iu of
vitamin A two days in a row before she
begins to show irritability.
Seizure info:
A few days after completing the high dose
vitamin A, I began trials of folinic acid and
methylcobalamin sublingual tabs. The
intent was to find something that would
allow her to tolerate B6. I settled on 1
capsule of folinic, 800 mcg given at the
same time as 2 mg of mB12. To my
surprise she stopped having head drops
and the amount of simple partials
declined significantly. I was quite excited
when I added B6, found that she now
tolerated it and stopped having seizures
of any type. It only takes about 24 hours
without her B vitamins and a simple
partial seizure will occur. She has not had
a head drop since starting the B12.
[My thanks to Sandra for allowing me to
use her story on my site.]