MARS SMALL BORE SCANNER

MARS Bioimaging Ltd

www.marsbioimaging.com

● X-ray imaging at histology levels

● Measures the concentration of materials (lipid, water, Au, Gd, Ca, I) in mg/mL

● Rapid imaging. 30mm diameter by 30mm length in 15 minutes

● Human-translatable: imaging parameters enable direct translation to human research

● Intuitive user interface with one click “scan-to-recon” operation

● Advanced image visualisation and analysis tools

Material quantification

Grey scale CT image MARS image

Clinical applications
Cartilage imaging
Measure glycosoaminoglycan
changes in osteoarthritis

Using routine x-ray contrast agents the gradient

of biochemical changes can be quantified

Cancer imaging
Better characterisation
and better drug delivery

The technology opens the door

to targeted imaging probes on CT

Gold-nano probes within a murine model of lung cancer,

with a 2D magic lens used to enhance the view of the region of interest

Multiple targeted agents

Many agents have their own spectral signatures gold
iodine
The MARS system can measure gadolinium
multiple targeting agents simultaneosly calcium
water
Clinical applications
Spectral imaging of atherosclerosis
Histological scale imaging of the components
of a plaque, including its lipid-rich core
and micro-calcifications Reducing metal artifacts in bone
Streak and beam hardening artifacts
caused by metal can be removed

This enables clear visualisation

of the bone-metal interface

Water Calcium Lipid Combined

 MARS scanner specifications Reference sites
● Spectral range: 15-120 keV Rensselaer Polytechnic Institute
● Sample bed ready for gas lines, monitoring inputs Troy, New York, USA
and temperature sensors
University of Notre Dame
● Variable source and detector distances
giving variable magnification
South Bend, Indiana, USA

● Molecular image visualisation and analysis software

University of Otago
● MARS Vision workstation with HP zVR 3D Christchurch, New Zealand
interactive virtual reality system

● Radiation dose similar to conventional CT (20-80 mGy)

University of Canterbury
Christchurch, New Zealand
● LED illumination of the sample. HD webcam
for real-time sample monitoring

● Fully x-ray shielded cabinet on industrial,

locking caster wheels MARS Bioimaging Ltd
● Reconstruction, processing and PACS server
rack-mounted inside scanner
www.marsbioimaging.com
sales@marsbioimaging.com
● Data acquired and stored in a standard
medical format (DICOM)

● Adjustable filters, and x, y automatic tracking collimators

● Small footprint - fits through most doorways:

75 x 140 x 117 cm, 450 kg