Documente Academic
Documente Profesional
Documente Cultură
Prostaglandin Both PGE2&PGF2 alpha have an 1) For induction 1)Hypersensitivity 1) Assess patient RR,
oxytocic effects on the pregnant of a abortion 2) Uterine rhythm & depth, vaginal
uterus. They have sensitized the during 2nd fibroids discharge,
myometrium to oxytocin. PGF2 trimester & 3) Cervical itching/irritation
alpha acts predominantly on the expulsion of stenosis 2) Administer
myometrium, while PGE2 acts hydatidiform 4) PID antiemetic/
mainly on the cervix mole antidiarrheal
2) For induction preparation prior to
of labour in IUD giving this drug, high in
of foetus vagina, after warming
3) In the suppository by
augmentation/ running water over the
acceleration of package
labour 3) Evaluate patient for
4) To stop length& duration of
bleeding from the contractions, notify
open uterine physician of
sinuses as in contractions lasting
refractory cases over 1minute or
of atonic PPH absence of contractions,
Cervical ripening fever& chills
4) Advise patient to
remain supine for 10-15
minutes after vaginal
insertion.
Sr. Name of drug Doses M.O. A Indication Contra-indication Nursing responsibilities
no
1) Epidosin Orally: 10 – It is both central and peripheral 1) Cervical 1) Paralytic ileus 1) Advise patient to
(valethmate 20mg in a antimuscarininc agent, which is a dilation in the 2) Myasthenia report for any blurred
bromide) day competitive inhibitor of first stage of gravis vision, giddiness, dry
Parenteral: 4 acetylcholine at the muscarinic labour. 3) mouth immediately
- 8mg receptor 2) Symptomatic Ulcerative colitis 2) Advise patient to get
relief of GI tract 4) Closed angle up from the bed
and ureteric colic glaucoma carefully and slowly.
5) CVS disorders 3) Advise do not drive or
6) Alcohol operate machinery
7) Benign 4) Advise take
prostatic precautions if you have
hyperplasia thyrotoxicosis, cardiac
8) Tachycardia insufficiency, cardiac
9) Sever hepatic failure and cardiac
and renal surgery
impairment
10) Pyloric
stenosis
11) Megacolon
Sr. Name of drug Doses M.O. A Indications Contra-indication Nursing responsibilities
no
Misoprostol 800mg as a It binds to myometrial cells to 1) Cervical 1)Previous 1) Administer this drug
single dose cause strong myometrial dilation before caesarean section to prevent stomach
contractions leading to expulsion aspiration or 2) Grand ulcers, take it by mouth
of tissue. This agent also causes curettage multiparity usually four times a day,
cervical ripening with the 2) First trimester 3) Ectopic after meals and at
softening and dilation of the incomplete pregnancy bedtime to minimize
cervix abortion 4) Foetal distress diarrhoea, or as
3) Termination of 5) Incomplete directed by your doctor
intra-uterine abortion 2) Avoids taking
pregnancy 6) Placenta Previa antacids that contain
4) Induction of Infection magnesium while using
labour 7) Abnormal misoprostol because
5) Treatment of foetal position they may make the
post-partum 8) Vasa Previa diarrhoea it cause
haemorrhage 9) Ulcerative worse
6) Atonic uterus colitis 3) For ulcer prevention
continue to take this
drug for as long as you
take
Sr. Name of drug Doses M.O. A Indication Contra-indication Nursing responsibilities
no
Methotrexate 25mg/ml 1) It is an antimetabolite that 1) Patient must 1) Breast feeding 1) Solution for injection
binds to the enzyme dihydrololete be 2)Immunodeficie must be prepared in a
seducrase , which is involved in hemodynamically ncy biologic cabinet. Gloves,
syntheses of purine nucleotides. stable, with the 3) Alcoholism gown and mask are
This interference with DNA no S/S of active 4) Blood worn while preparing
syntheses and disputes cell bleeding dysceasias and handling the
multiplication 2) Gestational 5) Leukopenia medication
2) Used in treatment of ectopic size shouldn’t 6) Peptic ulcer 2) Administer
pregnancy single or multiple IM exceed 4cm on 7) Anaemia allopurinol per doctor’s
injection is given USG 8) order to decrease uric
measurement Hypersensitivity level
3) Absence of 3) Instruct patient to
fetal cardiac avoid caffeine as it may
activity on USG decrease the efficacy of
finding the drug
4) No evidence of 4) To prevent
tubal rupture hematologic toxicity
5) B- HCG level salicylates, NSAIDS,
less than phenytoin, tetracycline,
5000mIu/ml should be avoided
6) Rheumatoid
arthritis
7) Ectopic
pregnancy
8) Leukaemia
Sr. Name of drug Doses M.O. A Indication Contra- indication Nursing responsibilities
no
Calcium Neonate Calcium gluconate is the 1)Severe 1) Do not Assess for cutaneous
gluconate 2ml/kg gluconate salt of calcium. An hypocalcaemia administer to burning sensation and
Adult :10 ml element or mineral necessary for 2) Hypocalcaemia patients with peripheral vasodilation
by slow IV normal nerve, muscle, and tetany severe renal with the moderate fall
injection cardiac function. The uptake and 3) Neonatal disease or patient in BP, during direct IV
binding of amino acids, hypocalcaemia receiving cardiac injection
absorption of vitamin B 12 and 4) Symptomatic glycosides Monitor ECG during IV
gastric secretion hypomagnesemia 2) Do not administration to detect
administer by IM evidence of
or SC route (pain hypocalcaemia;
and risk of tissue decreased QT interval
necrosis or associated with inverted
abscess T wave
formation at Observe IV site closely.
injection site, Extravasation may
especially in result in tissue irritation
infants and and necrosis
children) Monitor for
hypocalcaemia and
hypercalcaemia
Do not breast feed
while taking this drug
without consulting
physician.